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Items: 1 to 50 of 181

1.

Sunbeds and Melanoma Risk: Many Open Questions, Not Yet Time to Close the Debate.

Reichrath J, Lindqvist PG, Pilz S, März W, Grant WB, Holick MF, DE Gruijl FR.

Anticancer Res. 2020 Jan;40(1):501-509. doi: 10.21873/anticanres.13978. Review.

PMID:
31892605
2.

Everyday sunscreen use may compromise vitamin D in temperate climes.

De Gruijl FR, Webb AR, Rhodes LE.

Br J Dermatol. 2019 Dec 19. doi: 10.1111/bjd.18811. [Epub ahead of print]

PMID:
31853945
3.

Human health in relation to exposure to solar ultraviolet radiation under changing stratospheric ozone and climate.

Lucas RM, Yazar S, Young AR, Norval M, de Gruijl FR, Takizawa Y, Rhodes LE, Sinclair CA, Neale RE.

Photochem Photobiol Sci. 2019 Mar 1;18(3):641-680. doi: 10.1039/c8pp90060d. Epub 2019 Feb 27.

PMID:
30810559
4.

Sun Exposure Public Health Directives.

Hoel DG, de Gruijl FR.

Int J Environ Res Public Health. 2018 Dec 10;15(12). pii: E2794. doi: 10.3390/ijerph15122794.

5.

Commemorative issue in honour of Jan van der Leun, 14 June 1928-6 July 2016.

Bornman JF, de Gruijl FR.

Photochem Photobiol Sci. 2018 Dec 5;17(12):1815. doi: 10.1039/c8pp90050g. No abstract available.

PMID:
30483685
6.

Low wintertime pre-diagnostic vitamin D status is associated with an increased risk of internal malignancies in kidney transplant recipients.

de Gruijl FR, Wolterbeek R, Pavel S, de Fijter JW, Hamdy NAT, Bouwes Bavinck JN.

Photochem Photobiol Sci. 2018 Dec 5;17(12):1946-1955. doi: 10.1039/c7pp00404d.

PMID:
30397693
7.

Pathogenesis of Skin Carcinomas and a Stem Cell as Focal Origin.

de Gruijl FR, Tensen CP.

Front Med (Lausanne). 2018 May 29;5:165. doi: 10.3389/fmed.2018.00165. eCollection 2018. Review.

8.

Fractional Sunburn Threshold UVR Doses Generate Equivalent Vitamin D and DNA Damage in Skin Types I-VI but with Epidermal DNA Damage Gradient Correlated to Skin Darkness.

Shih BB, Farrar MD, Cooke MS, Osman J, Langton AK, Kift R, Webb AR, Berry JL, Watson REB, Vail A, de Gruijl FR, Rhodes LE.

J Invest Dermatol. 2018 Oct;138(10):2244-2252. doi: 10.1016/j.jid.2018.04.015. Epub 2018 May 3.

9.

Environmental effects of ozone depletion, UV radiation and interactions with climate change: UNEP Environmental Effects Assessment Panel, update 2017.

Bais AF, Lucas RM, Bornman JF, Williamson CE, Sulzberger B, Austin AT, Wilson SR, Andrady AL, Bernhard G, McKenzie RL, Aucamp PJ, Madronich S, Neale RE, Yazar S, Young AR, de Gruijl FR, Norval M, Takizawa Y, Barnes PW, Robson TM, Robinson SA, Ballaré CL, Flint SD, Neale PJ, Hylander S, Rose KC, Wängberg SÅ, Häder DP, Worrest RC, Zepp RG, Paul ND, Cory RM, Solomon KR, Longstreth J, Pandey KK, Redhwi HH, Torikai A, Heikkilä AM.

Photochem Photobiol Sci. 2018 Feb 14;17(2):127-179. doi: 10.1039/c7pp90043k.

10.

A Critical Appraisal of the Recent Reports on Sunbeds from the European Commission's Scientific Committee on Health, Environmental and Emerging Risks and from the World Health Organization.

Reichrath J, Lindqvist PG, DE Gruijl FR, Pilz S, Kimball SM, Grant WB, Holick MF.

Anticancer Res. 2018 Feb;38(2):1111-1120. Review.

PMID:
29374748
11.

RNA-seq analysis of Lgr6+ stem cells and identification of an Lgr6 isoform.

van de Glind GC, Bastidas Torres AN, Zoutman WH, van der Zeeuw SAJ, Kiełbasa SM, de Gruijl FR, Tensen CP.

Exp Dermatol. 2018 Oct;27(10):1172-1175. doi: 10.1111/exd.13453. Epub 2017 Dec 20.

PMID:
28987003
12.

UV adaptation: Pigmentation and protection against overexposure.

de Gruijl FR.

Exp Dermatol. 2017 Jul;26(7):557-562. doi: 10.1111/exd.13332. Epub 2017 May 9. Review.

PMID:
28266726
13.

The risks and benefits of sun exposure 2016.

Hoel DG, Berwick M, de Gruijl FR, Holick MF.

Dermatoendocrinol. 2016 Oct 19;8(1):e1248325. eCollection 2016 Jan-Dec. Review.

14.

Lgr6+ stem cells and their progeny in mouse epidermis under regimens of exogenous skin carcinogenesis, and their absence in ensuing skin tumors.

van de Glind GC, Rebel HG, Out-Luiting JJ, Zoutman W, Tensen CP, de Gruijl FR.

Oncotarget. 2016 Dec 27;7(52):86740-86754. doi: 10.18632/oncotarget.13436.

15.

p16 immunostaining in keratinocytic neoplasia in organ transplant recipients: Bowen's disease shows a characteristic pattern.

Genders RE, Beck S, Bouwes Bavinck JN, van den Munckhof HA, Kouwenhoven ST, de Koning MN, de Gruijl FR, Jenkins D, Willemze R, Quint KD.

J Cutan Pathol. 2017 Jan;44(1):28-33. doi: 10.1111/cup.12840. Epub 2016 Oct 25.

PMID:
27717097
16.

For better or for worse, UV in psoriasis.

de Gruijl FR.

Exp Dermatol. 2016 Dec;25(12):945-946. doi: 10.1111/exd.13216. No abstract available.

PMID:
27673561
17.

Concurrent beneficial (vitamin D production) and hazardous (cutaneous DNA damage) impact of repeated low-level summer sunlight exposures.

Felton SJ, Cooke MS, Kift R, Berry JL, Webb AR, Lam PM, de Gruijl FR, Vail A, Rhodes LE.

Br J Dermatol. 2016 Dec;175(6):1320-1328. doi: 10.1111/bjd.14863. Epub 2016 Nov 18.

18.

Lgr5+ stem cells and their progeny in mouse epidermis under regimens of exogenous skin carcinogenesis, and their absence in ensuing skin tumors.

van de Glind GC, Out-Luiting JJ, Rebel HG, Tensen CP, de Gruijl FR.

Oncotarget. 2016 Aug 9;7(32):52085-52094. doi: 10.18632/oncotarget.10475.

19.

Studying skin tumourigenesis and progression in immunocompetent hairless SKH1-hr mice using chronic 7,12-dimethylbenz(a)anthracene topical applications to develop a useful experimental skin cancer model.

Thomas G, Tuk B, Song JY, Truong H, Gerritsen HC, de Gruijl FR, Sterenborg HJ.

Lab Anim. 2017 Feb;51(1):24-35. doi: 10.1177/0023677216637305. Epub 2016 Jul 10.

PMID:
26946120
20.

Distribution of GNAQ and GNA11 Mutation Signatures in Uveal Melanoma Points to a Light Dependent Mutation Mechanism.

de Lange MJ, Razzaq L, Versluis M, Verlinde S, Dogrusöz M, Böhringer S, Marinkovic M, Luyten GP, de Keizer RJ, de Gruijl FR, Jager MJ, van der Velden PA.

PLoS One. 2015 Sep 14;10(9):e0138002. doi: 10.1371/journal.pone.0138002. eCollection 2015.

21.

The mastocyte: the off switch of UV itch.

de Gruijl FR.

Exp Dermatol. 2015 Jul;24(7):489-90. doi: 10.1111/exd.12742. No abstract available.

PMID:
25940228
22.

Predicted increased risk of squamous cell carcinoma induction associated with sunbed exposure habits.

Tierney P, de Gruijl FR, Ibbotson S, Moseley H.

Br J Dermatol. 2015 Jul;173(1):201-8. doi: 10.1111/bjd.13714. Epub 2015 May 26.

PMID:
25645571
23.

Robust detection of minimal sunburn in pigmented skin by 785 nm laser speckle contrast imaging of blood flux.

Shih BB, Allan D, de Gruijl FR, Rhodes LE.

J Invest Dermatol. 2015 Apr;135(4):1197-1199. doi: 10.1038/jid.2014.507. Epub 2014 Nov 28. No abstract available.

24.

The consequences for human health of stratospheric ozone depletion in association with other environmental factors.

Lucas RM, Norval M, Neale RE, Young AR, de Gruijl FR, Takizawa Y, van der Leun JC.

Photochem Photobiol Sci. 2015 Jan;14(1):53-87. doi: 10.1039/c4pp90033b.

25.

UV exposure inhibits intestinal tumor growth and progression to malignancy in intestine-specific Apc mutant mice kept on low vitamin D diet.

Rebel H, der Spek CD, Salvatori D, van Leeuwen JP, Robanus-Maandag EC, de Gruijl FR.

Int J Cancer. 2015 Jan 15;136(2):271-7. doi: 10.1002/ijc.29002. Epub 2014 Jun 5.

26.

Comment on Sallander et al. 'Vitamin D levels after UVB radiation: effects by UVA additions in a randomized controlled trial'.

Norval M, de Gruijl FR.

Photodermatol Photoimmunol Photomed. 2014 Aug;30(4):176-7. doi: 10.1111/phpp.12122. Epub 2014 Jun 9. No abstract available.

PMID:
24684201
27.

No acceleration of UV-induced skin carcinogenesis from evenly spread dietary intake of cyclosporine in contrast to oral bolus dosages.

Voskamp P, Bodmann CA, Koehl GE, Tensen CP, Bavinck JN, Willemze R, Geissler EK, de Gruijl FR.

Transplantation. 2013 Nov 27;96(10):871-6. doi: 10.1097/TP.0b013e3182a3dfa3.

PMID:
23958926
28.

Molecular profiling of cutaneous squamous cell carcinomas and actinic keratoses from organ transplant recipients.

Hameetman L, Commandeur S, Bavinck JN, Wisgerhof HC, de Gruijl FR, Willemze R, Mullenders L, Tensen CP, Vrieling H.

BMC Cancer. 2013 Feb 5;13:58. doi: 10.1186/1471-2407-13-58.

29.

Dietary immunosuppressants do not enhance UV-induced skin carcinogenesis, and reveal discordance between p53-mutant early clones and carcinomas.

Voskamp P, Bodmann CA, Koehl GE, Rebel HG, Van Olderen MG, Gaumann A, El Ghalbzouri A, Tensen CP, Bavinck JN, Willemze R, Geissler EK, De Gruijl FR.

Cancer Prev Res (Phila). 2013 Feb;6(2):129-38. doi: 10.1158/1940-6207.CAPR-12-0361. Epub 2012 Dec 11.

30.

The effects of a mid-winter 8-week course of sub-sunburn sunbed exposures on tanning, vitamin D status and colds.

de Gruijl FR, Pavel S.

Photochem Photobiol Sci. 2012 Dec;11(12):1848-54. doi: 10.1039/c2pp25179e.

PMID:
23104230
31.

Epidermal growth factor receptor activation and inhibition in 3D in vitro models of normal skin and human cutaneous squamous cell carcinoma.

Commandeur S, van Drongelen V, de Gruijl FR, El Ghalbzouri A.

Cancer Sci. 2012 Dec;103(12):2120-6. doi: 10.1111/cas.12026. Epub 2012 Oct 26.

32.

Environmental effects of ozone depletion and its interactions with climate change: progress report, 2011.

United Nations Environment Programme, Environmental Effects Assessment Panel, Andrady AL, Aucamp PJ, Austin AT, Bais AF, Ballaré CL, Björn LO, Bornman JF, Caldwell M, Cullen AP, Erickson DJ, de Gruijl FR, Häder DP, He W, Ilyas M, Longstreth J, Lucas R, McKenzie RL, Madronich S, Norval M, Paul ND, Redhwi HH, Robinson S, Shao M, Solomon KR, Sulzberger B, Takizawa Y, Tang X, Torikai A, van der Leun JC, Williamson CE, Wilson SR, Worrest RC, Zepp RG.

Photochem Photobiol Sci. 2012 Jan;11(1):13-27.

PMID:
22279621
33.

Human papillomavirus 8 E6 disrupts terminal skin differentiation and prevents pro-Caspase-14 cleavage.

Kazem S, van der Meijden E, Struijk L, de Gruijl FR, Feltkamp MC.

Virus Res. 2012 Feb;163(2):609-16. doi: 10.1016/j.virusres.2011.12.015. Epub 2011 Dec 31.

PMID:
22230316
34.

UV-induced ablation of the epidermal basal layer including p53-mutant clones resets UV carcinogenesis showing squamous cell carcinomas to originate from interfollicular epidermis.

Rebel HG, Bodmann CA, van de Glind GC, de Gruijl FR.

Carcinogenesis. 2012 Mar;33(3):714-20. doi: 10.1093/carcin/bgs004. Epub 2012 Jan 6.

PMID:
22227037
35.

Ingenol mebutate field-directed treatment of UVB-damaged skin reduces lesion formation and removes mutant p53 patches.

Cozzi SJ, Ogbourne SM, James C, Rebel HG, de Gruijl FR, Ferguson B, Gardner J, Lee TT, Larcher T, Suhrbier A.

J Invest Dermatol. 2012 Apr;132(4):1263-71. doi: 10.1038/jid.2011.418. Epub 2011 Dec 22.

36.

Rapamycin impairs UV induction of mutant-p53 overexpressing cell clusters without affecting tumor onset.

Voskamp P, Bodmann CA, Rebel HG, Koehl GE, Tensen CP, Bouwes Bavinck JN, El Ghalbzouri A, Van Kranen HJ, Willemze R, Geissler EK, De Gruijl FR.

Int J Cancer. 2012 Sep 15;131(6):1267-76. doi: 10.1002/ijc.27391. Epub 2012 Jan 27.

37.

Skin hardening effect in patients with polymorphic light eruption: comparison of UVB hardening in hospital with a novel home UV-hardening device.

Franken SM, Genders RE, de Gruijl FR, Rustemeyer T, Pavel S.

J Eur Acad Dermatol Venereol. 2013 Jan;27(1):67-72. doi: 10.1111/j.1468-3083.2011.04358.x. Epub 2011 Dec 6.

PMID:
22142537
38.

The sun's vitamin against sun allergy.

De Gruijl FR.

Br J Dermatol. 2011 Jul;165(1):2-3. doi: 10.1111/j.1365-2133.2011.10421.x. No abstract available.

PMID:
21707571
39.

Functional characterization of cancer-associated fibroblasts of human cutaneous squamous cell carcinoma.

Commandeur S, Ho SH, de Gruijl FR, Willemze R, Tensen CP, El Ghalbzouri A.

Exp Dermatol. 2011 Sep;20(9):737-42. doi: 10.1111/j.1600-0625.2011.01305.x. Epub 2011 May 25.

PMID:
21615509
40.

Sufficient vitamin D from casual sun exposure?

de Gruijl FR.

Photochem Photobiol. 2011 May-Jun;87(3):598-601. doi: 10.1111/j.1751-1097.2011.00918.x. Epub 2011 Apr 6.

PMID:
21388384
41.

The human health effects of ozone depletion and interactions with climate change.

Norval M, Lucas RM, Cullen AP, de Gruijl FR, Longstreth J, Takizawa Y, van der Leun JC.

Photochem Photobiol Sci. 2011 Feb;10(2):199-225. doi: 10.1039/c0pp90044c. Epub 2011 Jan 20. Review.

PMID:
21253670
42.

Enhanced global genome nucleotide excision repair reduces UV carcinogenesis and nullifies strand bias in p53 mutations in Csb-/- mice.

Pines A, Hameetman L, de Wilde J, Alekseev S, de Gruijl FR, Vrieling H, Mullenders LH.

J Invest Dermatol. 2010 Jun;130(6):1746-9. doi: 10.1038/jid.2010.18. Epub 2010 Feb 11. No abstract available.

43.

Is the action spectrum for the UV-induced production of previtamin D3 in human skin correct?

Norval M, Björn LO, de Gruijl FR.

Photochem Photobiol Sci. 2010 Jan;9(1):11-7. doi: 10.1039/b9pp00012g. Epub 2009 Oct 19. Review.

PMID:
20062839
44.

Error-prone translesion replication of damaged DNA suppresses skin carcinogenesis by controlling inflammatory hyperplasia.

Tsaalbi-Shtylik A, Verspuy JW, Jansen JG, Rebel H, Carlée LM, van der Valk MA, Jonkers J, de Gruijl FR, de Wind N.

Proc Natl Acad Sci U S A. 2009 Dec 22;106(51):21836-41. doi: 10.1073/pnas.0909507106. Epub 2009 Dec 10.

45.

Early and late effects of the immunosuppressants rapamycin and mycophenolate mofetil on UV carcinogenesis.

de Gruijl FR, Koehl GE, Voskamp P, Strik A, Rebel HG, Gaumann A, de Fijter JW, Tensen CP, Bavinck JN, Geissler EK.

Int J Cancer. 2010 Aug 15;127(4):796-804. doi: 10.1002/ijc.25097.

46.

Polymorphic light eruption occurs in 18% of Europeans and does not show higher prevalence with increasing latitude: multicenter survey of 6,895 individuals residing from the Mediterranean to Scandinavia.

Rhodes LE, Bock M, Janssens AS, Ling TC, Anastasopoulou L, Antoniou C, Aubin F, Bruckner T, Faivre B, Gibbs NK, Jansen C, Pavel S, Stratigos AJ, de Gruijl FR, Diepgen TL.

J Invest Dermatol. 2010 Feb;130(2):626-8. doi: 10.1038/jid.2009.250. Epub 2009 Aug 20. No abstract available.

47.

An in vitro three-dimensional model of primary human cutaneous squamous cell carcinoma.

Commandeur S, de Gruijl FR, Willemze R, Tensen CP, El Ghalbzouri A.

Exp Dermatol. 2009 Oct;18(10):849-56. doi: 10.1111/j.1600-0625.2009.00856.x. Epub 2009 Mar 12.

PMID:
19469895
48.

Photocarcinogenesis--DNA damage and gene mutations.

de Gruijl FR, Voskamp P.

Cancer Treat Res. 2009;146:101-8. doi: 10.1007/978-0-387-78574-5_9. Review. No abstract available.

PMID:
19415196
49.

Comment on "In vitro model of vitamin D(3) (cholecalciferol) synthesis by UV radiation: dose-response relationships" by W.J. Olds, A.R. McKinley, M.R. Moore and M.G. Kimlin, J. Photochem. Photobiol. B: Biol. 93 (2008) 88-93.

Björn LO, de Gruijl FR, Norval M, Dmitrenko O.

J Photochem Photobiol B. 2009 May 4;95(2):138-9. doi: 10.1016/j.jphotobiol.2009.01.006. Epub 2009 Feb 12.

PMID:
19269846
50.

Environmental effects of ozone depletion and its interactions with climate change: progress report, 2008.

Andrady A, Aucamp PJ, Bais A, Ballaré CL, Björn LO, Bornman JF, Caldwell M, Cullen AP, Erickson DJ, de Gruijl FR, Häder DP, Ilyas M, Kulandaivelu G, Kumar HD, Longstreth J, McKenzie RL, Norval M, Paul N, Redhwi HH, Smith RC, Solomon KR, Sulzberger B, Takizawa Y, Tang X, Teramura AH, Torikai A, van der Leun JC, Wilson SR, Worrest RC, Zepp RG; United Nations Environment Programme, Environmental Effects Assessment Panel.

Photochem Photobiol Sci. 2009 Jan;8(1):13-22.

PMID:
19256109

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