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Items: 1 to 50 of 57

1.

Humans and Chimpanzees Display Opposite Patterns of Diversity in Arylamine N-Acetyltransferase Genes.

Vangenot C, Gagneux P, de Groot NG, Baumeyer A, Mouterde M, Crouau-Roy B, Darlu P, Sanchez-Mazas A, Sabbagh A, Poloni ES.

G3 (Bethesda). 2019 Jul 9;9(7):2199-2224. doi: 10.1534/g3.119.400223.

2.

Extensive Alternative Splicing of KIR Transcripts.

Bruijnesteijn J, van der Wiel MKH, de Groot N, Otting N, de Vos-Rouweler AJM, Lardy NM, de Groot NG, Bontrop RE.

Front Immunol. 2018 Dec 4;9:2846. doi: 10.3389/fimmu.2018.02846. eCollection 2018.

3.

Correction to: Limited MHC class II gene polymorphism in the West African chimpanzee is distributed maximally by haplotype diversity.

Otting N, de Groot NG, Bontrop RE.

Immunogenetics. 2018 Nov;70(10):689-691. doi: 10.1007/s00251-018-1089-8.

PMID:
30283990
4.

Limited MHC class II gene polymorphism in the West African chimpanzee is distributed maximally by haplotype diversity.

Otting N, de Groot NG, Bontrop RE.

Immunogenetics. 2019 Jan;71(1):13-23. doi: 10.1007/s00251-018-1080-4. Epub 2018 Aug 29. Erratum in: Immunogenetics. 2018 Nov;70(10):689-691.

PMID:
30159708
5.

Does the MHC Confer Protection against Malaria in Bonobos?

de Groot NG, Stevens JMG, Bontrop RE.

Trends Immunol. 2018 Oct;39(10):768-771. doi: 10.1016/j.it.2018.07.004. Epub 2018 Aug 17.

PMID:
30126696
6.

IPD-MHC: nomenclature requirements for the non-human major histocompatibility complex in the next-generation sequencing era.

Maccari G, Robinson J, Bontrop RE, Otting N, de Groot NG, Ho CS, Ballingall KT, Marsh SGE, Hammond JA.

Immunogenetics. 2018 Nov;70(10):619-623. doi: 10.1007/s00251-018-1072-4. Epub 2018 Jul 19.

7.

Nomenclature for the KIR of non-human species.

Robinson J, Guethlein LA, Maccari G, Blokhuis J, Bimber BN, de Groot NG, Sanderson ND, Abi-Rached L, Walter L, Bontrop RE, Hammond JA, Marsh SGE, Parham P.

Immunogenetics. 2018 Sep;70(9):571-583. doi: 10.1007/s00251-018-1064-4. Epub 2018 Jun 4.

8.

MHC class I diversity of olive baboons (Papio anubis) unravelled by next-generation sequencing.

van der Wiel MKH, Doxiadis GGM, de Groot N, Otting N, de Groot NG, Poirier N, Blancho G, Bontrop RE.

Immunogenetics. 2018 Jul;70(7):439-448. doi: 10.1007/s00251-018-1053-7. Epub 2018 Feb 24.

9.

Human and Rhesus Macaque KIR Haplotypes Defined by Their Transcriptomes.

Bruijnesteijn J, van der Wiel MKH, Swelsen WTN, Otting N, de Vos-Rouweler AJM, Elferink D, Doxiadis GG, Claas FHJ, Lardy NM, de Groot NG, Bontrop RE.

J Immunol. 2018 Mar 1;200(5):1692-1701. doi: 10.4049/jimmunol.1701480. Epub 2018 Jan 22.

10.

A Specialist Macaque MHC Class I Molecule with HLA-B*27-like Peptide-Binding Characteristics.

de Groot NG, Heijmans CMC, de Ru AH, Janssen GMC, Drijfhout JW, Otting N, Vangenot C, Doxiadis GGM, Koning F, van Veelen PA, Bontrop RE.

J Immunol. 2017 Nov 15;199(10):3679-3690. doi: 10.4049/jimmunol.1700502. Epub 2017 Oct 11.

11.

AIDS in chimpanzees: the role of MHC genes.

de Groot NG, Heijmans CMC, Bontrop RE.

Immunogenetics. 2017 Aug;69(8-9):499-509. doi: 10.1007/s00251-017-1006-6. Epub 2017 Jul 10. Review.

PMID:
28695283
12.

Limited MHC class I intron 2 repertoire variation in bonobos.

de Groot NG, Heijmans CMC, Helsen P, Otting N, Pereboom Z, Stevens JMG, Bontrop RE.

Immunogenetics. 2017 Oct;69(10):677-688. doi: 10.1007/s00251-017-1010-x. Epub 2017 Jun 16.

PMID:
28623393
13.

Two Orangutan Species Have Evolved Different KIR Alleles and Haplotypes.

Guethlein LA, Norman PJ, Heijmans CM, de Groot NG, Hilton HG, Babrzadeh F, Abi-Rached L, Bontrop RE, Parham P.

J Immunol. 2017 Apr 15;198(8):3157-3169. doi: 10.4049/jimmunol.1602163. Epub 2017 Mar 6.

14.

A quick and robust MHC typing method for free-ranging and captive primate species.

de Groot N, Stanbury K, de Vos-Rouweler AJ, de Groot NG, Poirier N, Blancho G, de Luna C, Doxiadis GG, Bontrop RE.

Immunogenetics. 2017 Apr;69(4):231-240. doi: 10.1007/s00251-016-0968-0. Epub 2017 Jan 13.

15.

IPD-MHC 2.0: an improved inter-species database for the study of the major histocompatibility complex.

Maccari G, Robinson J, Ballingall K, Guethlein LA, Grimholt U, Kaufman J, Ho CS, de Groot NG, Flicek P, Bontrop RE, Hammond JA, Marsh SG.

Nucleic Acids Res. 2017 Jan 4;45(D1):D860-D864. doi: 10.1093/nar/gkw1050. Epub 2016 Nov 28.

16.

The orthologs of HLA-DQ and -DP genes display abundant levels of variability in macaque species.

Otting N, van der Wiel MK, de Groot N, de Vos-Rouweler AJ, de Groot NG, Doxiadis GG, Wiseman RW, O'Connor DH, Bontrop RE.

Immunogenetics. 2017 Feb;69(2):87-99. doi: 10.1007/s00251-016-0954-6. Epub 2016 Oct 22.

PMID:
27771735
17.

Complex MHC Class I Gene Transcription Profiles and Their Functional Impact in Orangutans.

de Groot NG, Heijmans CM, van der Wiel MK, Blokhuis JH, Mulder A, Guethlein LA, Doxiadis GG, Claas FH, Parham P, Bontrop RE.

J Immunol. 2016 Jan 15;196(2):750-8. doi: 10.4049/jimmunol.1500820. Epub 2015 Dec 18.

18.

Co-evolution of the MHC class I and KIR gene families in rhesus macaques: ancestry and plasticity.

de Groot NG, Blokhuis JH, Otting N, Doxiadis GG, Bontrop RE.

Immunol Rev. 2015 Sep;267(1):228-45. doi: 10.1111/imr.12313. Review.

19.

Strong vaccine-induced CD8 T-cell responses have cytolytic function in a chimpanzee clearing HCV infection.

Verstrepen BE, Verschoor EJ, Fagrouch ZC, Mooij P, de Groot NG, Bontrop RE, Bogers WM, Heeney JL, Koopman G.

PLoS One. 2014 Apr 16;9(4):e95103. doi: 10.1371/journal.pone.0095103. eCollection 2014.

20.

Unique peptide-binding motif for Mamu-B*037:01: an MHC class I allele common to Indian and Chinese rhesus macaques.

de Groot NG, Heijmans CM, de Ru AH, Hassan C, Otting N, Doxiadis GG, Koning F, van Veelen PA, Bontrop RE.

Immunogenetics. 2013 Dec;65(12):897-900. doi: 10.1007/s00251-013-0734-5. Epub 2013 Sep 17.

PMID:
24042460
21.

The repertoire of MHC class I genes in the common marmoset: evidence for functional plasticity.

van der Wiel MK, Otting N, de Groot NG, Doxiadis GG, Bontrop RE.

Immunogenetics. 2013 Dec;65(12):841-9. doi: 10.1007/s00251-013-0732-7. Epub 2013 Sep 10.

PMID:
24018468
22.

Haplotype diversity generated by ancient recombination-like events in the MHC of Indian rhesus macaques.

Doxiadis GG, de Groot N, Otting N, de Vos-Rouweler AJ, Bolijn MJ, Heijmans CM, de Groot NG, van der Wiel MK, Remarque EJ, Vangenot C, Nunes JM, Sanchez-Mazas A, Bontrop RE.

Immunogenetics. 2013 Aug;65(8):569-84. doi: 10.1007/s00251-013-0707-8. Epub 2013 May 29.

23.

The HIV-1 pandemic: does the selective sweep in chimpanzees mirror humankind's future?

de Groot NG, Bontrop RE.

Retrovirology. 2013 May 24;10:53. doi: 10.1186/1742-4690-10-53. Review.

24.

Evaluation of IL-28B polymorphisms and serum IP-10 in hepatitis C infected chimpanzees.

Verstrepen BE, de Groot NG, Groothuismink ZM, Verschoor EJ, de Groen RA, Bogers WM, Janssen HL, Mooij P, Bontrop RE, Koopman G, Boonstra A.

PLoS One. 2012;7(10):e46645. doi: 10.1371/journal.pone.0046645. Epub 2012 Oct 30.

25.

Nomenclature report on the major histocompatibility complex genes and alleles of Great Ape, Old and New World monkey species.

de Groot NG, Otting N, Robinson J, Blancher A, Lafont BA, Marsh SG, O'Connor DH, Shiina T, Walter L, Watkins DI, Bontrop RE.

Immunogenetics. 2012 Aug;64(8):615-31. doi: 10.1007/s00251-012-0617-1. Epub 2012 Apr 18.

26.

TRIM5 allelic polymorphism in macaque species/populations of different geographic origins: its impact on SIV vaccine studies.

de Groot NG, Heijmans CM, Koopman G, Verschoor EJ, Bogers WM, Bontrop RE.

Tissue Antigens. 2011 Oct;78(4):256-62. doi: 10.1111/j.1399-0039.2011.01768.x.

PMID:
21929574
27.

AIDS-protective HLA-B*27/B*57 and chimpanzee MHC class I molecules target analogous conserved areas of HIV-1/SIVcpz.

de Groot NG, Heijmans CM, Zoet YM, de Ru AH, Verreck FA, van Veelen PA, Drijfhout JW, Doxiadis GG, Remarque EJ, Doxiadis II, van Rood JJ, Koning F, Bontrop RE.

Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15175-80. doi: 10.1073/pnas.1009136107. Epub 2010 Aug 9.

28.

Extensive DRB region diversity in cynomolgus macaques: recombination as a driving force.

Doxiadis GG, de Groot N, de Groot NG, Rotmans G, de Vos-Rouweler AJ, Bontrop RE.

Immunogenetics. 2010 Mar;62(3):137-47. doi: 10.1007/s00251-010-0422-7. Epub 2010 Feb 4.

29.

The chimpanzee Mhc-DRB region revisited: gene content, polymorphism, pseudogenes, and transcripts.

de Groot NG, Heijmans CM, de Groot N, Doxiadis GG, Otting N, Bontrop RE.

Mol Immunol. 2009 Dec;47(2-3):381-9. doi: 10.1016/j.molimm.2009.09.003. Epub 2009 Oct 2.

30.

Correlated evolution of nucleotide substitution rates and allelic variation in Mhc-DRB lineages of primates.

Garamszegi LZ, de Groot NG, Bontrop RE.

BMC Evol Biol. 2009 Apr 12;9:73. doi: 10.1186/1471-2148-9-73.

31.

Patterns of diversity in HIV-related loci among subspecies of chimpanzee: concordance at CCR5 and differences at CXCR4 and CX3CR1.

MacFie TS, Nerrienet E, de Groot NG, Bontrop RE, Mundy NI.

Mol Biol Evol. 2009 Apr;26(4):719-27. doi: 10.1093/molbev/msp016. Epub 2009 Jan 30.

PMID:
19182224
32.

Comparative genetics of a highly divergent DRB microsatellite in different macaque species.

de Groot N, Doxiadis GG, de Vos-Rouweler AJ, de Groot NG, Verschoor EJ, Bontrop RE.

Immunogenetics. 2008 Dec;60(12):737-48. doi: 10.1007/s00251-008-0333-z. Epub 2008 Oct 28.

33.

A snapshot of the Mamu-B genes and their allelic repertoire in rhesus macaques of Chinese origin.

Otting N, Heijmans CM, van der Wiel M, de Groot NG, Doxiadis GG, Bontrop RE.

Immunogenetics. 2008 Sep;60(9):507-14. doi: 10.1007/s00251-008-0311-5. Epub 2008 Jul 11.

34.

Reshuffling of ancient peptide binding motifs between HLA-DRB multigene family members: old wine served in new skins.

Doxiadis GG, de Groot N, de Groot NG, Doxiadis II, Bontrop RE.

Mol Immunol. 2008 May;45(10):2743-51. doi: 10.1016/j.molimm.2008.02.017.

PMID:
18395261
35.

Pinpointing a selective sweep to the chimpanzee MHC class I region by comparative genomics.

de Groot NG, Heijmans CM, de Groot N, Otting N, de Vos-Rouweller AJ, Remarque EJ, Bonhomme M, Doxiadis GG, Crouau-Roy B, Bontrop RE.

Mol Ecol. 2008 Apr;17(8):2074-88. doi: 10.1111/j.1365-294X.2008.03716.x. Epub 2008 Mar 10.

PMID:
18346126
36.

MHC class I A region diversity and polymorphism in macaque species.

Otting N, de Vos-Rouweler AJ, Heijmans CM, de Groot NG, Doxiadis GG, Bontrop RE.

Immunogenetics. 2007 May;59(5):367-75. Epub 2007 Mar 3.

37.

Reactivation by exon shuffling of a conserved HLA-DR3-like pseudogene segment in a New World primate species.

Doxiadis GG, van der Wiel MK, Brok HP, de Groot NG, Otting N, 't Hart BA, van Rood JJ, Bontrop RE.

Proc Natl Acad Sci U S A. 2006 Apr 11;103(15):5864-8. Epub 2006 Mar 31.

38.

Extensive sharing of MHC class II alleles between rhesus and cynomolgus macaques.

Doxiadis GG, Rouweler AJ, de Groot NG, Louwerse A, Otting N, Verschoor EJ, Bontrop RE.

Immunogenetics. 2006 May;58(4):259-68. Epub 2006 Feb 10.

PMID:
16470376
39.

Microsatellite typing of the rhesus macaque MHC region.

Penedo MC, Bontrop RE, Heijmans CM, Otting N, Noort R, Rouweler AJ, de Groot N, de Groot NG, Ward T, Doxiadis GG.

Immunogenetics. 2005 May;57(3-4):198-209. Epub 2005 Apr 5.

PMID:
15900491
40.

Reduced MIC gene repertoire variation in West African chimpanzees as compared to humans.

de Groot NG, Garcia CA, Verschoor EJ, Doxiadis GG, Marsh SG, Otting N, Bontrop RE.

Mol Biol Evol. 2005 Jun;22(6):1375-85. Epub 2005 Mar 9.

PMID:
15758205
41.

Unparalleled complexity of the MHC class I region in rhesus macaques.

Otting N, Heijmans CM, Noort RC, de Groot NG, Doxiadis GG, van Rood JJ, Watkins DI, Bontrop RE.

Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1626-31. Epub 2005 Jan 21.

42.

Allelic polymorphism in introns 1 and 2 of the HLA-DQA1 gene.

Voorter CE, de Groot NG, Meertens CM, Bontrop RE, van den Berg-Loonen EM.

Tissue Antigens. 2005 Jan;65(1):56-66.

PMID:
15663742
43.

Genetic makeup of the DR region in rhesus macaques: gene content, transcripts, and pseudogenes.

de Groot N, Doxiadis GG, De Groot NG, Otting N, Heijmans C, Rouweler AJ, Bontrop RE.

J Immunol. 2004 May 15;172(10):6152-7.

44.

Evolutionary stability of MHC class II haplotypes in diverse rhesus macaque populations.

Doxiadis GG, Otting N, de Groot NG, de Groot N, Rouweler AJ, Noort R, Verschoor EJ, Bontjer I, Bontrop RE.

Immunogenetics. 2003 Nov;55(8):540-51. Epub 2003 Oct 18.

PMID:
14566434
45.

Evidence for an ancient selective sweep in the MHC class I gene repertoire of chimpanzees.

de Groot NG, Otting N, Doxiadis GG, Balla-Jhagjhoorsingh SS, Heeney JL, van Rood JJ, Gagneux P, Bontrop RE.

Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11748-53. Epub 2002 Aug 19.

46.

Extensive Mhc-DQB variation in humans and non-human primate species.

Otting N, de Groot NG, Doxiadis GG, Bontrop RE.

Immunogenetics. 2002 Jul;54(4):230-9. Epub 2002 Jun 20.

PMID:
12136334
47.

Differential evolutionary MHC class II strategies in humans and rhesus macaques: relevance for biomedical studies.

Doxiadis GG, Otting N, de Groot NG, Bontrop RE.

Immunol Rev. 2001 Oct;183:76-85. Review.

PMID:
11782248
48.

Allelic diversity of Mhc-DRB alleles in rhesus macaques.

Otting N, de Groot NG, Noort MC, Doxiadis GG, Bontrop RE.

Tissue Antigens. 2000 Jul;56(1):58-68.

PMID:
10958357
49.

Myelin/oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis in common marmosets: the encephalitogenic T cell epitope pMOG24-36 is presented by a monomorphic MHC class II molecule.

Brok HP, Uccelli A, Kerlero De Rosbo N, Bontrop RE, Roccatagliata L, de Groot NG, Capello E, Laman JD, Nicolay K, Mancardi GL, Ben-Nun A, Hart BA.

J Immunol. 2000 Jul 15;165(2):1093-101.

50.

Major histocompatibility complex class I diversity in a West African chimpanzee population: implications for HIV research.

de Groot NG, Otting N, Arg├╝ello R, Watkins DI, Doxiadis GG, Madrigal JA, Bontrop RE.

Immunogenetics. 2000 May;51(6):398-409.

PMID:
10866106

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