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Items: 1 to 50 of 97

1.

Analytical Performance and Clinicopathologic Correlation of Four Fecal Calprotectin Methods.

Pelkmans LPJ, de Groot MJM, Curvers J.

Am J Clin Pathol. 2019 Aug 1;152(3):392-398. doi: 10.1093/ajcp/aqz051.

PMID:
31152542
2.

Opportunistic salpingectomy in women undergoing hysterectomy: Results from the HYSTUB randomised controlled trial.

Van Lieshout LAM, Pijlman B, Vos MC, de Groot MJM, Houterman S, Coppus SFPJ, Harmsen MG, Vandenput I, Piek JMJ.

Maturitas. 2018 Jan;107:1-6. doi: 10.1016/j.maturitas.2017.09.012. Epub 2017 Oct 3.

PMID:
29169572
3.

Discovery of Clinical Candidate 4-[2-(5-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-1,3-thiazol-4-ylbenzenesulfonamide (PF-05089771): Design and Optimization of Diaryl Ether Aryl Sulfonamides as Selective Inhibitors of NaV1.7.

Swain NA, Batchelor D, Beaudoin S, Bechle BM, Bradley PA, Brown AD, Brown B, Butcher KJ, Butt RP, Chapman ML, Denton S, Ellis D, Galan SRG, Gaulier SM, Greener BS, de Groot MJ, Glossop MS, Gurrell IK, Hannam J, Johnson MS, Lin Z, Markworth CJ, Marron BE, Millan DS, Nakagawa S, Pike A, Printzenhoff D, Rawson DJ, Ransley SJ, Reister SM, Sasaki K, Storer RI, Stupple PA, West CW.

J Med Chem. 2017 Aug 24;60(16):7029-7042. doi: 10.1021/acs.jmedchem.7b00598. Epub 2017 Aug 10.

PMID:
28682065
4.

Reference intervals and longitudinal changes in copeptin and MR-proADM concentrations during pregnancy.

Joosen AMCP, van der Linden IJM, Schrauwen L, Theeuwes A, de Groot MJM, Ermens AAM.

Clin Chem Lab Med. 2017 Nov 27;56(1):113-119. doi: 10.1515/cclm-2017-0110.

PMID:
28672769
5.

The Behavioral Consequence of Phenylketonuria in Mice Depends on the Genetic Background.

Bruinenberg VM, van der Goot E, van Vliet D, de Groot MJ, Mazzola PN, Heiner-Fokkema MR, van Faassen M, van Spronsen FJ, van der Zee EA.

Front Behav Neurosci. 2016 Dec 20;10:233. doi: 10.3389/fnbeh.2016.00233. eCollection 2016.

6.

Lactate point-of-care testing for acidosis: Cross-comparison of two devices with routine laboratory results.

van Horssen R, Schuurman TN, de Groot MJM, Jakobs BS.

Pract Lab Med. 2015 Dec 24;4:41-49. doi: 10.1016/j.plabm.2015.12.005. eCollection 2016 Apr 1.

7.

TSH and fT4 during pregnancy: an observational study and a review of the literature.

Joosen AM, van der Linden IJ, de Jong-Aarts N, Hermus MA, Ermens AA, de Groot MJ.

Clin Chem Lab Med. 2016 Jul 1;54(7):1239-46. doi: 10.1515/cclm-2015-0629.

PMID:
26641966
8.

Pregnancy diabetes: A comparison of diagnostic protocols based on point-of-care, routine and optimized laboratory conditions.

van den Berg SA, de Groot MJ, Salden LP, Draad PJ, Dijkstra IM, Lunshof S, van Thiel SW, Boonen KJ, Thelen MH.

Sci Rep. 2015 Nov 6;5:16302. doi: 10.1038/srep16302.

9.

The Mechanism Underlying the Brückner Effect Studied with an Automated, High-Resolution, Continuously Scanning Brückner Device.

de Groot MJ, van der Helm FC, Simonsz HJ.

Strabismus. 2015;23(2):85-100. doi: 10.3109/09273972.2015.1036081.

PMID:
26158475
10.

Thyrotropin versus age relation as an indicator of historical iodine intake.

van de Ven AC, Netea-Maier RT, Smit JW, Kusters R, van der Stappen JW, Pronk-Admiraal CJ, Buijs MM, Schoenmakers CH, Koehorst SG, de Groot MJ, Sweep FC, Hermus AR, den Heijer M.

Thyroid. 2015 Jun;25(6):629-34. doi: 10.1089/thy.2014.0574. Epub 2015 Apr 20.

PMID:
25811973
11.

BH4 treatment in BH4-responsive PKU patients: preliminary data on blood prolactin concentrations suggest increased cerebral dopamine concentrations.

van Vliet D, Anjema K, Jahja R, de Groot MJ, Liemburg GB, Heiner-Fokkema MR, van der Zee EA, Derks TG, Kema IP, van Spronsen FJ.

Mol Genet Metab. 2015 Jan;114(1):29-33. doi: 10.1016/j.ymgme.2014.11.009. Epub 2014 Nov 15.

PMID:
25466353
12.

Phenylketonuria: brain phenylalanine concentrations relate inversely to cerebral protein synthesis.

de Groot MJ, Sijens PE, Reijngoud DJ, Paans AM, van Spronsen FJ.

J Cereb Blood Flow Metab. 2015 Feb;35(2):200-5. doi: 10.1038/jcbfm.2014.183. Epub 2014 Oct 29.

13.

Salivary morning androstenedione and 17α-OH progesterone levels in childhood and puberty in patients with classic congenital adrenal hyperplasia.

de Groot MJ, Pijnenburg-Kleizen KJ, Thomas CM, Sweep FC, Stikkelbroeck NM, Otten BJ, Claahsen-van der Grinten HL.

Clin Chem Lab Med. 2015 Feb;53(3):461-8. doi: 10.1515/cclm-2014-0375.

PMID:
25283138
14.

From virtual to clinical: The discovery of PGN-1531, a novel antagonist of the prostanoid EP4 receptor.

Sutton J, Clark DE, Higgs C, de Groot MJ, Harris NV, Taylor A, Lockey PM, Maubach K, Woodrooffe A, Davis RJ, Coleman RA, Clark KL.

Bioorg Med Chem Lett. 2014 May 1;24(9):2212-21. doi: 10.1016/j.bmcl.2014.02.068. Epub 2014 Mar 12.

PMID:
24703233
15.

Single amino acid supplementation in aminoacidopathies: a systematic review.

van Vliet D, Derks TG, van Rijn M, de Groot MJ, MacDonald A, Heiner-Fokkema MR, van Spronsen FJ.

Orphanet J Rare Dis. 2014 Jan 13;9:7. doi: 10.1186/1750-1172-9-7. Review.

16.

Phenylketonuria: reduced tyrosine brain influx relates to reduced cerebral protein synthesis.

de Groot MJ, Hoeksma M, Reijngoud DJ, de Valk HW, Paans AM, Sauer PJ, van Spronsen FJ.

Orphanet J Rare Dis. 2013 Sep 4;8:133. doi: 10.1186/1750-1172-8-133.

17.

Quantum mechanics/molecular mechanics modeling of regioselectivity of drug metabolism in cytochrome P450 2C9.

Lonsdale R, Houghton KT, Żurek J, Bathelt CM, Foloppe N, de Groot MJ, Harvey JN, Mulholland AJ.

J Am Chem Soc. 2013 May 29;135(21):8001-15. doi: 10.1021/ja402016p. Epub 2013 May 16.

18.

Relationships between lumbar bone mineral density and biochemical parameters in phenylketonuria patients.

de Groot MJ, Hoeksma M, van Rijn M, Slart RH, van Spronsen FJ.

Mol Genet Metab. 2012 Apr;105(4):566-70. doi: 10.1016/j.ymgme.2012.01.006. Epub 2012 Jan 16.

PMID:
22300845
19.

The diagnostic performance of allergen-molecules in comparison to allergen-extracts.

van der Linden IJ, de Groot MJ, de Jong NC, Bozkurt Z, Cobbaert CM.

Clin Chem Lab Med. 2011 Oct 6;50(1):129-32. doi: 10.1515/CCLM.2011.729.

PMID:
21973104
20.

Understanding ion channels using computational approaches.

de Groot MJ.

Future Med Chem. 2010 May;2(5):697-701. doi: 10.4155/fmc.10.177. No abstract available.

21.

Large neutral amino acids in the treatment of PKU: from theory to practice.

van Spronsen FJ, de Groot MJ, Hoeksma M, Reijngoud DJ, van Rijn M.

J Inherit Metab Dis. 2010 Dec;33(6):671-6. doi: 10.1007/s10545-010-9216-1. Epub 2010 Oct 26. Review.

22.

Metabolic investigations prevent liver transplantation in two young children with citrullinemia type I.

de Groot MJ, Cuppen M, Eling M, Verheijen FW, Rings EH, Reijngoud DJ, de Vries MM, van Spronsen FJ.

J Inherit Metab Dis. 2010 Dec;33 Suppl 3:S413-6. doi: 10.1007/s10545-010-9207-2. Epub 2010 Sep 18.

23.

Pathogenesis of cognitive dysfunction in phenylketonuria: review of hypotheses.

de Groot MJ, Hoeksma M, Blau N, Reijngoud DJ, van Spronsen FJ.

Mol Genet Metab. 2010;99 Suppl 1:S86-9. doi: 10.1016/j.ymgme.2009.10.016. Review.

PMID:
20123477
24.

Subtype-selective targeting of voltage-gated sodium channels.

England S, de Groot MJ.

Br J Pharmacol. 2009 Nov;158(6):1413-25. doi: 10.1111/j.1476-5381.2009.00437.x. Epub 2009 Oct 20. Review.

25.

A three-way proteomics strategy allows differential analysis of yeast mitochondrial membrane protein complexes under anaerobic and aerobic conditions.

Helbig AO, de Groot MJ, van Gestel RA, Mohammed S, de Hulster EA, Luttik MA, Daran-Lapujade P, Pronk JT, Heck AJ, Slijper M.

Proteomics. 2009 Oct;9(20):4787-98. doi: 10.1002/pmic.200800951.

PMID:
19750512
26.

Metabolite and reaction inference based on enzyme specificities.

de Groot MJ, van Berlo RJ, van Winden WA, Verheijen PJ, Reinders MJ, de Ridder D.

Bioinformatics. 2009 Nov 15;25(22):2975-82. doi: 10.1093/bioinformatics/btp507. Epub 2009 Aug 20.

27.

Understanding CYP2D6 interactions.

de Groot MJ, Wakenhut F, Whitlock G, Hyland R.

Drug Discov Today. 2009 Oct;14(19-20):964-72. doi: 10.1016/j.drudis.2009.07.005. Epub 2009 Jul 26. Review.

PMID:
19638317
28.

Metabolic pathway alignment between species using a comprehensive and flexible similarity measure.

Li Y, de Ridder D, de Groot MJ, Reinders MJ.

BMC Syst Biol. 2008 Dec 24;2:111. doi: 10.1186/1752-0509-2-111.

29.

Analytical performance evaluation of the Cobas 6000 analyzer - special emphasis on trueness verification.

van Gammeren AJ, van Gool N, de Groot MJ, Cobbaert CM.

Clin Chem Lab Med. 2008;46(6):863-71. doi: 10.1515/CCLM.2008.159.

PMID:
18601611
30.

Quantitative proteomics and transcriptomics of anaerobic and aerobic yeast cultures reveals post-transcriptional regulation of key cellular processes.

de Groot MJ, Daran-Lapujade P, van Breukelen B, Knijnenburg TA, de Hulster EA, Reinders MJ, Pronk JT, Heck AJ, Slijper M.

Microbiology. 2007 Nov;153(Pt 11):3864-78.

PMID:
17975095
31.

The fluxes through glycolytic enzymes in Saccharomyces cerevisiae are predominantly regulated at posttranscriptional levels.

Daran-Lapujade P, Rossell S, van Gulik WM, Luttik MA, de Groot MJ, Slijper M, Heck AJ, Daran JM, de Winde JH, Westerhoff HV, Pronk JT, Bakker BM.

Proc Natl Acad Sci U S A. 2007 Oct 2;104(40):15753-8. Epub 2007 Sep 26.

32.

Predicting penetration across the blood-brain barrier from simple descriptors and fragmentation schemes.

Zhao YH, Abraham MH, Ibrahim A, Fish PV, Cole S, Lewis ML, de Groot MJ, Reynolds DP.

J Chem Inf Model. 2007 Jan-Feb;47(1):170-5.

PMID:
17238262
33.

Pharmacophoric fingerprint method (TOPP) for 3D-QSAR modeling: application to CYP2D6 metabolic stability.

Sciabola S, Morao I, de Groot MJ.

J Chem Inf Model. 2007 Jan-Feb;47(1):76-84.

PMID:
17238251
34.

Selection and characterisation of a xylitol-derepressed Aspergillus niger mutant that is apparently impaired in xylitol transport.

van de Vondervoort PJ, de Groot MJ, Ruijter GJ, Visser J.

Appl Microbiol Biotechnol. 2006 Dec;73(4):881-6. Epub 2006 Aug 25.

PMID:
16932954
35.

The discovery of CCR5 receptor antagonists for the treatment of HIV infection: hit-to-lead studies.

Armour D, de Groot MJ, Edwards M, Perros M, Price DA, Stammen BL, Wood A.

ChemMedChem. 2006 Jul;1(7):706-9. No abstract available.

PMID:
16902922
36.

Designing better drugs: predicting cytochrome P450 metabolism.

de Groot MJ.

Drug Discov Today. 2006 Jul;11(13-14):601-6.

PMID:
16793528
37.

The discovery of tropane-derived CCR5 receptor antagonists.

Armour DR, de Groot MJ, Price DA, Stammen BL, Wood A, Perros M, Burt C.

Chem Biol Drug Des. 2006 Apr;67(4):305-8.

PMID:
16629828
38.

Metabolic control analysis of Aspergillus niger L-arabinose catabolism.

de Groot MJ, Prathumpai W, Visser J, Ruijter GJ.

Biotechnol Prog. 2005 Nov-Dec;21(6):1610-6.

PMID:
16321042
39.

Drug binding interactions in the inner cavity of HERG channels: molecular insights from structure-activity relationships of clofilium and ibutilide analogs.

Perry M, Stansfeld PJ, Leaney J, Wood C, de Groot MJ, Leishman D, Sutcliffe MJ, Mitcheson JS.

Mol Pharmacol. 2006 Feb;69(2):509-19. Epub 2005 Nov 16.

PMID:
16291873
40.

Surface-integral QSPR models: local energy properties.

Ehresmann B, de Groot MJ, Clark T.

J Chem Inf Model. 2005 Jul-Aug;45(4):1053-60.

PMID:
16045301
41.

Greater than the sum of its parts: combining models for useful ADMET prediction.

O'Brien SE, de Groot MJ.

J Med Chem. 2005 Feb 24;48(4):1287-91.

PMID:
15715500
42.

In silico methods for predicting ligand binding determinants of cytochromes P450.

de Groot MJ, Kirton SB, Sutcliffe MJ.

Curr Top Med Chem. 2004;4(16):1803-24. Review.

PMID:
15579109
43.

Structural determinants of HERG channel block by clofilium and ibutilide.

Perry M, de Groot MJ, Helliwell R, Leishman D, Tristani-Firouzi M, Sanguinetti MC, Mitcheson J.

Mol Pharmacol. 2004 Aug;66(2):240-9.

PMID:
15266014
44.

New molecular descriptors based on local properties at the molecular surface and a boiling-point model derived from them.

Ehresmann B, de Groot MJ, Alex A, Clark T.

J Chem Inf Comput Sci. 2004 Mar-Apr;44(2):658-68.

PMID:
15032548
45.

Metabolic control analysis of xylose catabolism in Aspergillus.

Prathumpai W, Gabelgaard JB, Wanchanthuek P, van de Vondervoort PJ, de Groot MJ, McIntyre M, Nielsen J.

Biotechnol Prog. 2003 Jul-Aug;19(4):1136-41.

PMID:
12892473
46.

Isolation and characterization of two specific regulatory Aspergillus niger mutants shows antagonistic regulation of arabinan and xylan metabolism.

de Groot MJ, van de Vondervoort PJ, de Vries RP, vanKuyk PA, Ruijter GJ, Visser J.

Microbiology. 2003 May;149(Pt 5):1183-91.

PMID:
12724380
47.

Genetic basis for differential activities of fluconazole and voriconazole against Candida krusei.

Fukuoka T, Johnston DA, Winslow CA, de Groot MJ, Burt C, Hitchcock CA, Filler SG.

Antimicrob Agents Chemother. 2003 Apr;47(4):1213-9.

48.

Development of a combined protein and pharmacophore model for cytochrome P450 2C9.

de Groot MJ, Alex AA, Jones BC.

J Med Chem. 2002 May 9;45(10):1983-93.

PMID:
11985466
49.

Pharmacophore modeling of cytochromes P450.

de Groot MJ, Ekins S.

Adv Drug Deliv Rev. 2002 Mar 31;54(3):367-83. Review.

PMID:
11922953
50.

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