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Items: 16


Ultraviolet Photodissociation of ESI- and MALDI-Generated Protein Ions on a Q-Exactive Mass Spectrometer.

Dilillo M, de Graaf EL, Yadav A, Belov ME, McDonnell LA.

J Proteome Res. 2019 Jan 4;18(1):557-564. doi: 10.1021/acs.jproteome.8b00896. Epub 2018 Dec 4.


Mass Spectrometry Imaging, Laser Capture Microdissection, and LC-MS/MS of the Same Tissue Section.

Dilillo M, Pellegrini D, Ait-Belkacem R, de Graaf EL, Caleo M, McDonnell LA.

J Proteome Res. 2017 Aug 4;16(8):2993-3001. doi: 10.1021/acs.jproteome.7b00284. Epub 2017 Jul 5.


Design and Performance of a Novel Interface for Combined Matrix-Assisted Laser Desorption Ionization at Elevated Pressure and Electrospray Ionization with Orbitrap Mass Spectrometry.

Belov ME, Ellis SR, Dilillo M, Paine MRL, Danielson WF, Anderson GA, de Graaf EL, Eijkel GB, Heeren RMA, McDonnell LA.

Anal Chem. 2017 Jul 18;89(14):7493-7501. doi: 10.1021/acs.analchem.7b01168. Epub 2017 Jun 28.


Set of Novel Automated Quantitative Microproteomics Protocols for Small Sample Amounts and Its Application to Kidney Tissue Substructures.

de Graaf EL, Pellegrini D, McDonnell LA.

J Proteome Res. 2016 Dec 2;15(12):4722-4730. Epub 2016 Nov 10.


In-Source Decay and Pseudo-MS3 of Peptide and Protein Ions Using Liquid AP-MALDI.

Ait-Belkacem R, Dilillo M, Pellegrini D, Yadav A, de Graaf EL, McDonnell LA.

J Am Soc Mass Spectrom. 2016 Dec;27(12):2075-2079. Epub 2016 Oct 17.


Electrophysiology of glioma: a Rho GTPase-activating protein reduces tumor growth and spares neuron structure and function.

Vannini E, Olimpico F, Middei S, Ammassari-Teule M, de Graaf EL, McDonnell L, Schmidt G, Fabbri A, Fiorentini C, Baroncelli L, Costa M, Caleo M.

Neuro Oncol. 2016 Dec;18(12):1634-1643. Epub 2016 Jun 13.


Assessment of SRM, MRM(3) , and DIA for the targeted analysis of phosphorylation dynamics in non-small cell lung cancer.

Schmidlin T, Garrigues L, Lane CS, Mulder TC, van Doorn S, Post H, de Graaf EL, Lemeer S, Heck AJ, Altelaar AF.

Proteomics. 2016 Aug;16(15-16):2193-205. doi: 10.1002/pmic.201500453. Epub 2016 Jun 27.


Signal Transduction Reaction Monitoring Deciphers Site-Specific PI3K-mTOR/MAPK Pathway Dynamics in Oncogene-Induced Senescence.

de Graaf EL, Kaplon J, Mohammed S, Vereijken LA, Duarte DP, Redondo Gallego L, Heck AJ, Peeper DS, Altelaar AF.

J Proteome Res. 2015 Jul 2;14(7):2906-14. doi: 10.1021/acs.jproteome.5b00236. Epub 2015 Jun 2.


Dot1 histone methyltransferases share a distributive mechanism but have highly diverged catalytic properties.

Stulemeijer IJ, De Vos D, van Harten K, Joshi OK, Blomberg O, van Welsem T, Terweij M, Vlaming H, de Graaf EL, Altelaar AF, Bakker BM, van Leeuwen F.

Sci Rep. 2015 May 12;5:9824. doi: 10.1038/srep09824.


Flexibility in crosstalk between H2B ubiquitination and H3 methylation in vivo.

Vlaming H, van Welsem T, de Graaf EL, Ontoso D, Altelaar AF, San-Segundo PA, Heck AJ, van Leeuwen F.

EMBO Rep. 2014 Oct;15(10):1077-84. doi: 10.15252/embr.201438793. Epub 2014 Aug 20. Erratum in: EMBO Rep. 2014 Nov;15(11):1220-1.


Phosphoproteome dynamics in onset and maintenance of oncogene-induced senescence.

de Graaf EL, Kaplon J, Zhou H, Heck AJ, Peeper DS, Altelaar AF.

Mol Cell Proteomics. 2014 Aug;13(8):2089-100. doi: 10.1074/mcp.M113.035436. Epub 2014 Jun 24.


Single-step enrichment by Ti4+-IMAC and label-free quantitation enables in-depth monitoring of phosphorylation dynamics with high reproducibility and temporal resolution.

de Graaf EL, Giansanti P, Altelaar AF, Heck AJ.

Mol Cell Proteomics. 2014 Sep;13(9):2426-34. doi: 10.1074/mcp.O113.036608. Epub 2014 May 21.


Spatio-temporal analysis of molecular determinants of neuronal degeneration in the aging mouse cerebellum.

de Graaf EL, Vermeij WP, de Waard MC, Rijksen Y, van der Pluijm I, Hoogenraad CC, Hoeijmakers JH, Altelaar AF, Heck AJ.

Mol Cell Proteomics. 2013 May;12(5):1350-62. doi: 10.1074/mcp.M112.024950. Epub 2013 Feb 11.


Grade of deceased donor liver macrovesicular steatosis impacts graft and recipient outcomes more than the Donor Risk Index.

de Graaf EL, Kench J, Dilworth P, Shackel NA, Strasser SI, Joseph D, Pleass H, Crawford M, McCaughan GW, Verran DJ.

J Gastroenterol Hepatol. 2012 Mar;27(3):540-6. doi: 10.1111/j.1440-1746.2011.06844.x.


Progressive methylation of ageing histones by Dot1 functions as a timer.

De Vos D, Frederiks F, Terweij M, van Welsem T, Verzijlbergen KF, Iachina E, de Graaf EL, Altelaar AF, Oudgenoeg G, Heck AJ, Krijgsveld J, Bakker BM, van Leeuwen F.

EMBO Rep. 2011 Sep 1;12(9):956-62. doi: 10.1038/embor.2011.131.


Improving SRM assay development: a global comparison between triple quadrupole, ion trap, and higher energy CID peptide fragmentation spectra.

de Graaf EL, Altelaar AF, van Breukelen B, Mohammed S, Heck AJ.

J Proteome Res. 2011 Sep 2;10(9):4334-41. doi: 10.1021/pr200156b. Epub 2011 Jul 21.


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