Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 38

1.

The Dual Oxidase Duox2 stabilized with DuoxA2 in an enzymatic complex at the surface of the cell produces extracellular H2O2 able to induce DNA damage in an inducible cellular model.

Poncelet L, Dumont JE, Miot F, De Deken X.

Exp Cell Res. 2019 Sep 9:111620. doi: 10.1016/j.yexcr.2019.111620. [Epub ahead of print]

PMID:
31513783
2.

DUOX Defects and Their Roles in Congenital Hypothyroidism.

De Deken X, Miot F.

Methods Mol Biol. 2019;1982:667-693. doi: 10.1007/978-1-4939-9424-3_37.

PMID:
31172499
3.

Guidelines for the Detection of NADPH Oxidases by Immunoblot and RT-qPCR.

Diebold BA, Wilder SG, De Deken X, Meitzler JL, Doroshow JH, McCoy JW, Zhu Y, Lambeth JD.

Methods Mol Biol. 2019;1982:191-229. doi: 10.1007/978-1-4939-9424-3_12.

PMID:
31172474
4.

Wide Spectrum of DUOX2 Deficiency: From Life-Threatening Compressive Goiter in Infancy to Lifelong Euthyroidism.

Dufort G, Larrivée-Vanier S, Eugène D, De Deken X, Seebauer B, Heinimann K, Lévesque S, Gravel S, Szinnai G, Van Vliet G, Deladoëy J.

Thyroid. 2019 Jul;29(7):1018-1022. doi: 10.1089/thy.2018.0461. Epub 2019 May 31. Erratum in: Thyroid. 2019 Sep;29(9):1347.

PMID:
31030636
5.

Expression, Localization, and Regulation of the Sodium Bicarbonate Cotransporter NBCe1 in the Thyroid.

Virreira M, Jin L, Djerbib S, De Deken X, Miot F, Massart C, Svoboda M, Van Sande J, Beauwens R, Dumont JE, Boom A.

Thyroid. 2019 Feb;29(2):290-301. doi: 10.1089/thy.2017.0576. Epub 2019 Jan 23.

PMID:
30526387
6.

Factors contributing to the resistance of the thyrocyte to hydrogen peroxide.

Ghaddhab C, Kyrilli A, Driessens N, Van Den Eeckhaute E, Hancisse O, De Deken X, Dumont JE, Detours V, Miot F, Corvilain B.

Mol Cell Endocrinol. 2019 Feb 5;481:62-70. doi: 10.1016/j.mce.2018.11.010. Epub 2018 Nov 23.

PMID:
30476559
7.

A Rapid CRISPR/Cas-based Mutagenesis Assay in Zebrafish for Identification of Genes Involved in Thyroid Morphogenesis and Function.

Trubiroha A, Gillotay P, Giusti N, Gacquer D, Libert F, Lefort A, Haerlingen B, De Deken X, Opitz R, Costagliola S.

Sci Rep. 2018 Apr 4;8(1):5647. doi: 10.1038/s41598-018-24036-4.

8.

Autophagy regulates DUOX1 localization and superoxide production in airway epithelial cells during chronic IL-13 stimulation.

Dickinson JD, Sweeter JM, Warren KJ, Ahmad IM, De Deken X, Zimmerman MC, Brody SL.

Redox Biol. 2018 Apr;14:272-284. doi: 10.1016/j.redox.2017.09.013. Epub 2017 Sep 22.

9.

Cancer heterogeneity is not compatible with one unique cancer cell metabolic map.

Strickaert A, Saiselet M, Dom G, De Deken X, Dumont JE, Feron O, Sonveaux P, Maenhaut C.

Oncogene. 2017 May 11;36(19):2637-2642. doi: 10.1038/onc.2016.411. Epub 2016 Oct 31. Review.

10.

Overexpression of Interleukin-4 in the Thyroid of Transgenic Mice Upregulates the Expression of Duox1 and the Anion Transporter Pendrin.

Eskalli Z, Achouri Y, Hahn S, Many MC, Craps J, Refetoff S, Liao XH, Dumont JE, Van Sande J, Corvilain B, Miot F, De Deken X.

Thyroid. 2016 Oct;26(10):1499-1512.

11.

NADPH oxidase DUOX1 promotes long-term persistence of oxidative stress after an exposure to irradiation.

Ameziane-El-Hassani R, Talbot M, de Souza Dos Santos MC, Al Ghuzlan A, Hartl D, Bidart JM, De Deken X, Miot F, Diallo I, de Vathaire F, Schlumberger M, Dupuy C.

Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):5051-6. doi: 10.1073/pnas.1420707112. Epub 2015 Apr 6.

12.

Roles of DUOX-mediated hydrogen peroxide in metabolism, host defense, and signaling.

De Deken X, Corvilain B, Dumont JE, Miot F.

Antioxid Redox Signal. 2014 Jun 10;20(17):2776-93. doi: 10.1089/ars.2013.5602. Epub 2013 Oct 25. Review.

PMID:
24161126
13.

IFNβ/TNFα synergism induces a non-canonical STAT2/IRF9-dependent pathway triggering a novel DUOX2 NADPH oxidase-mediated airway antiviral response.

Fink K, Martin L, Mukawera E, Chartier S, De Deken X, Brochiero E, Miot F, Grandvaux N.

Cell Res. 2013 May;23(5):673-90. doi: 10.1038/cr.2013.47. Epub 2013 Apr 2. Erratum in: Cell Res. 2014 Apr;24(4):509.

14.

Stroma cell-derived factor-1α signaling enhances calcium transients and beating frequency in rat neonatal cardiomyocytes.

Hadad I, Veithen A, Springael JY, Sotiropoulou PA, Mendes Da Costa A, Miot F, Naeije R, De Deken X, Entee KM.

PLoS One. 2013;8(2):e56007. doi: 10.1371/journal.pone.0056007. Epub 2013 Feb 27.

15.

Thyroid hydrogen peroxide production is enhanced by the Th2 cytokines, IL-4 and IL-13, through increased expression of the dual oxidase 2 and its maturation factor DUOXA2.

Raad H, Eskalli Z, Corvilain B, Miot F, De Deken X.

Free Radic Biol Med. 2013 Mar;56:216-25. doi: 10.1016/j.freeradbiomed.2012.09.003. Epub 2012 Sep 23.

PMID:
23010498
16.

The type of DUOX-dependent ROS production is dictated by defined sequences in DUOXA.

Hoste C, Dumont JE, Miot F, De Deken X.

Exp Cell Res. 2012 Nov 1;318(18):2353-64. doi: 10.1016/j.yexcr.2012.07.007. Epub 2012 Jul 16.

PMID:
22814254
17.

Mice deficient in dual oxidase maturation factors are severely hypothyroid.

Grasberger H, De Deken X, Mayo OB, Raad H, Weiss M, Liao XH, Refetoff S.

Mol Endocrinol. 2012 Mar;26(3):481-92. doi: 10.1210/me.2011-1320. Epub 2012 Feb 2.

18.

Urothelial cells produce hydrogen peroxide through the activation of Duox1.

Donkó A, Ruisanchez E, Orient A, Enyedi B, Kapui R, Péterfi Z, de Deken X, Benyó Z, Geiszt M.

Free Radic Biol Med. 2010 Dec 15;49(12):2040-8. doi: 10.1016/j.freeradbiomed.2010.09.027.

PMID:
21146788
19.

The nonphagocytic NADPH oxidase Duox1 mediates a positive feedback loop during T cell receptor signaling.

Kwon J, Shatynski KE, Chen H, Morand S, de Deken X, Miot F, Leto TL, Williams MS.

Sci Signal. 2010 Aug 3;3(133):ra59. doi: 10.1126/scisignal.2000976.

20.
21.

H2O2, signal, substrate, mutagen and chemorepellent from physiology to biochemistry and disease.

Dumont JE, De Deken X, Miot F, Corvilain V, Contempré B, Goyens R, Massart C, Van Sande J, Allaoui A, Botteaux A.

Bull Mem Acad R Med Belg. 2010;165(5-6):231-4; discussion 235.

PMID:
21510483
22.

Association of duoxes with thyroid peroxidase and its regulation in thyrocytes.

Song Y, Ruf J, Lothaire P, Dequanter D, Andry G, Willemse E, Dumont JE, Van Sande J, De Deken X.

J Clin Endocrinol Metab. 2010 Jan;95(1):375-82. doi: 10.1210/jc.2009-1727. Epub 2009 Dec 1.

PMID:
19952225
23.

Dual oxidases and hydrogen peroxide in a complex dialogue between host mucosae and bacteria.

Allaoui A, Botteaux A, Dumont JE, Hoste C, De Deken X.

Trends Mol Med. 2009 Dec;15(12):571-9. doi: 10.1016/j.molmed.2009.10.003. Epub 2009 Nov 11.

PMID:
19913458
24.

Hydrogen peroxide induces DNA single- and double-strand breaks in thyroid cells and is therefore a potential mutagen for this organ.

Driessens N, Versteyhe S, Ghaddhab C, Burniat A, De Deken X, Van Sande J, Dumont JE, Miot F, Corvilain B.

Endocr Relat Cancer. 2009 Sep;16(3):845-56. doi: 10.1677/ERC-09-0020. Epub 2009 Jun 9.

PMID:
19509065
25.

Activation of dual oxidases Duox1 and Duox2: differential regulation mediated by camp-dependent protein kinase and protein kinase C-dependent phosphorylation.

Rigutto S, Hoste C, Grasberger H, Milenkovic M, Communi D, Dumont JE, Corvilain B, Miot F, De Deken X.

J Biol Chem. 2009 Mar 13;284(11):6725-34. doi: 10.1074/jbc.M806893200. Epub 2009 Jan 14.

26.

Genomewide location analysis of Candida albicans Upc2p, a regulator of sterol metabolism and azole drug resistance.

Znaidi S, Weber S, Al-Abdin OZ, Bomme P, Saidane S, Drouin S, Lemieux S, De Deken X, Robert F, Raymond M.

Eukaryot Cell. 2008 May;7(5):836-47. doi: 10.1128/EC.00070-08. Epub 2008 Apr 4.

27.

The zinc cluster transcription factor Tac1p regulates PDR16 expression in Candida albicans.

Znaidi S, De Deken X, Weber S, Rigby T, Nantel A, Raymond M.

Mol Microbiol. 2007 Oct;66(2):440-52.

28.

Roles of hydrogen peroxide in thyroid physiology and disease.

Song Y, Driessens N, Costa M, De Deken X, Detours V, Corvilain B, Maenhaut C, Miot F, Van Sande J, Many MC, Dumont JE.

J Clin Endocrinol Metab. 2007 Oct;92(10):3764-73. Epub 2007 Jul 31. Review.

PMID:
17666482
29.

Duox1 is the main source of hydrogen peroxide in the rat thyroid cell line PCCl3.

Rigutto S, Hoste C, Dumont JE, Corvilain B, Miot F, De Deken X.

Exp Cell Res. 2007 Nov 1;313(18):3892-901. Epub 2007 Jun 29.

PMID:
17643428
30.

Missense mutations of dual oxidase 2 (DUOX2) implicated in congenital hypothyroidism have impaired trafficking in cells reconstituted with DUOX2 maturation factor.

Grasberger H, De Deken X, Miot F, Pohlenz J, Refetoff S.

Mol Endocrinol. 2007 Jun;21(6):1408-21. Epub 2007 Mar 20.

PMID:
17374849
31.

Duox expression and related H2O2 measurement in mouse thyroid: onset in embryonic development and regulation by TSH in adult.

Milenkovic M, De Deken X, Jin L, De Felice M, Di Lauro R, Dumont JE, Corvilain B, Miot F.

J Endocrinol. 2007 Mar;192(3):615-26.

PMID:
17332529
32.

PDR16-mediated azole resistance in Candida albicans.

Saidane S, Weber S, De Deken X, St-Germain G, Raymond M.

Mol Microbiol. 2006 Jun;60(6):1546-62.

33.

Candida albicans zinc cluster protein Upc2p confers resistance to antifungal drugs and is an activator of ergosterol biosynthetic genes.

MacPherson S, Akache B, Weber S, De Deken X, Raymond M, Turcotte B.

Antimicrob Agents Chemother. 2005 May;49(5):1745-52.

34.

Identification of a novel partner of duox: EFP1, a thioredoxin-related protein.

Wang D, De Deken X, Milenkovic M, Song Y, Pirson I, Dumont JE, Miot F.

J Biol Chem. 2005 Jan 28;280(4):3096-103. Epub 2004 Nov 22.

35.
36.

Characterization of ThOX proteins as components of the thyroid H(2)O(2)-generating system.

De Deken X, Wang D, Dumont JE, Miot F.

Exp Cell Res. 2002 Feb 15;273(2):187-96.

PMID:
11822874
37.

Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family.

De Deken X, Wang D, Many MC, Costagliola S, Libert F, Vassart G, Dumont JE, Miot F.

J Biol Chem. 2000 Jul 28;275(30):23227-33.

38.

Decrease of telomere length in thyroid adenomas without telomerase activity.

De Deken X, Vilain C, Van Sande J, Dumont JE, Miot F.

J Clin Endocrinol Metab. 1998 Dec;83(12):4368-72.

PMID:
9851779

Supplemental Content

Loading ...
Support Center