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Items: 40

1.

Metabolism and Autoimmune Responses: The microRNA Connection.

Colamatteo A, Micillo T, Bruzzaniti S, Fusco C, Garavelli S, De Rosa V, Galgani M, Spagnuolo MI, Di Rella F, Puca AA, de Candia P, Matarese G.

Front Immunol. 2019 Aug 28;10:1969. doi: 10.3389/fimmu.2019.01969. eCollection 2019. Review.

2.

Extracellular vesicles circulating in young organisms promote healthy longevity.

Prattichizzo F, Giuliani A, Sabbatinelli J, Mensà E, De Nigris V, La Sala L, de Candia P, Olivieri F, Ceriello A.

J Extracell Vesicles. 2019 Aug 15;8(1):1656044. doi: 10.1080/20013078.2019.1656044. eCollection 2019.

3.

Type 2 Diabetes: How Much of an Autoimmune Disease?

de Candia P, Prattichizzo F, Garavelli S, De Rosa V, Galgani M, Di Rella F, Spagnuolo MI, Colamatteo A, Fusco C, Micillo T, Bruzzaniti S, Ceriello A, Puca AA, Matarese G.

Front Endocrinol (Lausanne). 2019 Jul 4;10:451. doi: 10.3389/fendo.2019.00451. eCollection 2019.

4.

Longevity-Associated Variant of BPIFB4 Mitigates Monocyte-Mediated Acquired Immune Response.

Ciaglia E, Montella F, Maciag A, Scala P, Ferrario A, Banco C, Carrizzo A, Spinelli CC, Cattaneo M, De Candia P, Vecchione C, Villa F, Puca AA.

J Gerontol A Biol Sci Med Sci. 2019 May 10. pii: glz036. doi: 10.1093/gerona/glz036. [Epub ahead of print]

PMID:
31074771
5.

Glatiramer Acetate modulates ion channels expression and calcium homeostasis in B cell of patients with relapsing-remitting multiple sclerosis.

Criscuolo C, Cianflone A, Lanzillo R, Carrella D, Carissimo A, Napolitano F, de Cegli R, de Candia P, La Rocca C, Petrozziello T, Matarese G, Boscia F, Secondo A, Di Bernardo D, Brescia Morra V.

Sci Rep. 2019 Mar 12;9(1):4208. doi: 10.1038/s41598-018-38152-8.

6.

Circulating microRNA-21 is an early predictor of ROS-mediated damage in subjects with high risk of developing diabetes and in drug-naïve T2D.

La Sala L, Mrakic-Sposta S, Tagliabue E, Prattichizzo F, Micheloni S, Sangalli E, Specchia C, Uccellatore AC, Lupini S, Spinetti G, de Candia P, Ceriello A.

Cardiovasc Diabetol. 2019 Feb 25;18(1):18. doi: 10.1186/s12933-019-0824-2.

7.

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines.

Théry C, Witwer KW, Aikawa E, Alcaraz MJ, Anderson JD, Andriantsitohaina R, Antoniou A, Arab T, Archer F, Atkin-Smith GK, Ayre DC, Bach JM, Bachurski D, Baharvand H, Balaj L, Baldacchino S, Bauer NN, Baxter AA, Bebawy M, Beckham C, Bedina Zavec A, Benmoussa A, Berardi AC, Bergese P, Bielska E, Blenkiron C, Bobis-Wozowicz S, Boilard E, Boireau W, Bongiovanni A, Borràs FE, Bosch S, Boulanger CM, Breakefield X, Breglio AM, Brennan MÁ, Brigstock DR, Brisson A, Broekman ML, Bromberg JF, Bryl-Górecka P, Buch S, Buck AH, Burger D, Busatto S, Buschmann D, Bussolati B, Buzás EI, Byrd JB, Camussi G, Carter DR, Caruso S, Chamley LW, Chang YT, Chen C, Chen S, Cheng L, Chin AR, Clayton A, Clerici SP, Cocks A, Cocucci E, Coffey RJ, Cordeiro-da-Silva A, Couch Y, Coumans FA, Coyle B, Crescitelli R, Criado MF, D'Souza-Schorey C, Das S, Datta Chaudhuri A, de Candia P, De Santana EF, De Wever O, Del Portillo HA, Demaret T, Deville S, Devitt A, Dhondt B, Di Vizio D, Dieterich LC, Dolo V, Dominguez Rubio AP, Dominici M, Dourado MR, Driedonks TA, Duarte FV, Duncan HM, Eichenberger RM, Ekström K, El Andaloussi S, Elie-Caille C, Erdbrügger U, Falcón-Pérez JM, Fatima F, Fish JE, Flores-Bellver M, Försönits A, Frelet-Barrand A, Fricke F, Fuhrmann G, Gabrielsson S, Gámez-Valero A, Gardiner C, Gärtner K, Gaudin R, Gho YS, Giebel B, Gilbert C, Gimona M, Giusti I, Goberdhan DC, Görgens A, Gorski SM, Greening DW, Gross JC, Gualerzi A, Gupta GN, Gustafson D, Handberg A, Haraszti RA, Harrison P, Hegyesi H, Hendrix A, Hill AF, Hochberg FH, Hoffmann KF, Holder B, Holthofer H, Hosseinkhani B, Hu G, Huang Y, Huber V, Hunt S, Ibrahim AG, Ikezu T, Inal JM, Isin M, Ivanova A, Jackson HK, Jacobsen S, Jay SM, Jayachandran M, Jenster G, Jiang L, Johnson SM, Jones JC, Jong A, Jovanovic-Talisman T, Jung S, Kalluri R, Kano SI, Kaur S, Kawamura Y, Keller ET, Khamari D, Khomyakova E, Khvorova A, Kierulf P, Kim KP, Kislinger T, Klingeborn M, Klinke DJ 2nd, Kornek M, Kosanović MM, Kovács ÁF, Krämer-Albers EM, Krasemann S, Krause M, Kurochkin IV, Kusuma GD, Kuypers S, Laitinen S, Langevin SM, Languino LR, Lannigan J, Lässer C, Laurent LC, Lavieu G, Lázaro-Ibáñez E, Le Lay S, Lee MS, Lee YXF, Lemos DS, Lenassi M, Leszczynska A, Li IT, Liao K, Libregts SF, Ligeti E, Lim R, Lim SK, Linē A, Linnemannstöns K, Llorente A, Lombard CA, Lorenowicz MJ, Lörincz ÁM, Lötvall J, Lovett J, Lowry MC, Loyer X, Lu Q, Lukomska B, Lunavat TR, Maas SL, Malhi H, Marcilla A, Mariani J, Mariscal J, Martens-Uzunova ES, Martin-Jaular L, Martinez MC, Martins VR, Mathieu M, Mathivanan S, Maugeri M, McGinnis LK, McVey MJ, Meckes DG Jr, Meehan KL, Mertens I, Minciacchi VR, Möller A, Møller Jørgensen M, Morales-Kastresana A, Morhayim J, Mullier F, Muraca M, Musante L, Mussack V, Muth DC, Myburgh KH, Najrana T, Nawaz M, Nazarenko I, Nejsum P, Neri C, Neri T, Nieuwland R, Nimrichter L, Nolan JP, Nolte-'t Hoen EN, Noren Hooten N, O'Driscoll L, O'Grady T, O'Loghlen A, Ochiya T, Olivier M, Ortiz A, Ortiz LA, Osteikoetxea X, Østergaard O, Ostrowski M, Park J, Pegtel DM, Peinado H, Perut F, Pfaffl MW, Phinney DG, Pieters BC, Pink RC, Pisetsky DS, Pogge von Strandmann E, Polakovicova I, Poon IK, Powell BH, Prada I, Pulliam L, Quesenberry P, Radeghieri A, Raffai RL, Raimondo S, Rak J, Ramirez MI, Raposo G, Rayyan MS, Regev-Rudzki N, Ricklefs FL, Robbins PD, Roberts DD, Rodrigues SC, Rohde E, Rome S, Rouschop KM, Rughetti A, Russell AE, Saá P, Sahoo S, Salas-Huenuleo E, Sánchez C, Saugstad JA, Saul MJ, Schiffelers RM, Schneider R, Schøyen TH, Scott A, Shahaj E, Sharma S, Shatnyeva O, Shekari F, Shelke GV, Shetty AK, Shiba K, Siljander PR, Silva AM, Skowronek A, Snyder OL 2nd, Soares RP, Sódar BW, Soekmadji C, Sotillo J, Stahl PD, Stoorvogel W, Stott SL, Strasser EF, Swift S, Tahara H, Tewari M, Timms K, Tiwari S, Tixeira R, Tkach M, Toh WS, Tomasini R, Torrecilhas AC, Tosar JP, Toxavidis V, Urbanelli L, Vader P, van Balkom BW, van der Grein SG, Van Deun J, van Herwijnen MJ, Van Keuren-Jensen K, van Niel G, van Royen ME, van Wijnen AJ, Vasconcelos MH, Vechetti IJ Jr, Veit TD, Vella LJ, Velot É, Verweij FJ, Vestad B, Viñas JL, Visnovitz T, Vukman KV, Wahlgren J, Watson DC, Wauben MH, Weaver A, Webber JP, Weber V, Wehman AM, Weiss DJ, Welsh JA, Wendt S, Wheelock AM, Wiener Z, Witte L, Wolfram J, Xagorari A, Xander P, Xu J, Yan X, Yáñez-Mó M, Yin H, Yuana Y, Zappulli V, Zarubova J, Žėkas V, Zhang JY, Zhao Z, Zheng L, Zheutlin AR, Zickler AM, Zimmermann P, Zivkovic AM, Zocco D, Zuba-Surma EK.

J Extracell Vesicles. 2018 Nov 23;7(1):1535750. doi: 10.1080/20013078.2018.1535750. eCollection 2018.

8.

The Multifaceted Interface Between Cytokines and microRNAs: An Ancient Mechanism to Regulate the Good and the Bad of Inflammation.

Garavelli S, De Rosa V, de Candia P.

Front Immunol. 2018 Dec 21;9:3012. doi: 10.3389/fimmu.2018.03012. eCollection 2018. Review.

9.

Leptin and ghrelin: Sewing metabolism onto neurodegeneration.

de Candia P, Matarese G.

Neuropharmacology. 2018 Jul 1;136(Pt B):307-316. doi: 10.1016/j.neuropharm.2017.12.025. Epub 2017 Dec 15. Review.

PMID:
29248481
10.

A unique plasma microRNA profile defines type 2 diabetes progression.

de Candia P, Spinetti G, Specchia C, Sangalli E, La Sala L, Uccellatore A, Lupini S, Genovese S, Matarese G, Ceriello A.

PLoS One. 2017 Dec 4;12(12):e0188980. doi: 10.1371/journal.pone.0188980. eCollection 2017.

11.

Immunometabolism of human autoimmune diseases: from metabolites to extracellular vesicles.

de Candia P, De Rosa V, Gigantino V, Botti G, Ceriello A, Matarese G.

FEBS Lett. 2017 Oct;591(19):3119-3134. doi: 10.1002/1873-3468.12733. Epub 2017 Jul 10. Review.

12.

Obstacles and opportunities in the functional analysis of extracellular vesicle RNA - an ISEV position paper.

Mateescu B, Kowal EJ, van Balkom BW, Bartel S, Bhattacharyya SN, Buzás EI, Buck AH, de Candia P, Chow FW, Das S, Driedonks TA, Fernández-Messina L, Haderk F, Hill AF, Jones JC, Van Keuren-Jensen KR, Lai CP, Lässer C, Liegro ID, Lunavat TR, Lorenowicz MJ, Maas SL, Mäger I, Mittelbrunn M, Momma S, Mukherjee K, Nawaz M, Pegtel DM, Pfaffl MW, Schiffelers RM, Tahara H, Théry C, Tosar JP, Wauben MH, Witwer KW, Nolte-'t Hoen EN.

J Extracell Vesicles. 2017 Mar 7;6(1):1286095. doi: 10.1080/20013078.2017.1286095. eCollection 2017.

13.

Extracellular MicroRNA Signature of Human Helper T Cell Subsets in Health and Autoimmunity.

Torri A, Carpi D, Bulgheroni E, Crosti MC, Moro M, Gruarin P, Rossi RL, Rossetti G, Di Vizio D, Hoxha M, Bollati V, Gagliani C, Tacchetti C, Paroni M, Geginat J, Corti L, Venegoni L, Berti E, Pagani M, Matarese G, Abrignani S, de Candia P.

J Biol Chem. 2017 Feb 17;292(7):2903-2915. doi: 10.1074/jbc.M116.769893. Epub 2017 Jan 11.

14.

Metabolic control of immune tolerance in health and autoimmunity.

Carbone F, La Rocca C, De Candia P, Procaccini C, Colamatteo A, Micillo T, De Rosa V, Matarese G.

Semin Immunol. 2016 Oct;28(5):491-504. doi: 10.1016/j.smim.2016.09.006. Epub 2016 Oct 5. Review.

PMID:
27720234
15.

Role of metabolism in neurodegenerative disorders.

Procaccini C, Santopaolo M, Faicchia D, Colamatteo A, Formisano L, de Candia P, Galgani M, De Rosa V, Matarese G.

Metabolism. 2016 Sep;65(9):1376-90. doi: 10.1016/j.metabol.2016.05.018. Epub 2016 Jun 7. Review.

PMID:
27506744
16.

Extracellular RNAs: A Secret Arm of Immune System Regulation.

de Candia P, De Rosa V, Casiraghi M, Matarese G.

J Biol Chem. 2016 Apr 1;291(14):7221-8. doi: 10.1074/jbc.R115.708842. Epub 2016 Feb 17. Review.

17.

Focus on Extracellular Vesicles: New Frontiers of Cell-to-Cell Communication in Cancer.

Ciardiello C, Cavallini L, Spinelli C, Yang J, Reis-Sobreiro M, de Candia P, Minciacchi VR, Di Vizio D.

Int J Mol Sci. 2016 Feb 6;17(2):175. doi: 10.3390/ijms17020175. Review.

18.

The circulating microRNome demonstrates distinct lymphocyte subset-dependent signatures.

de Candia P, Torri A, Fedeli M, Viganò V, Carpi D, Gorletta T, Casorati G, Pagani M, Dellabona P, Abrignani S.

Eur J Immunol. 2016 Mar;46(3):725-31. doi: 10.1002/eji.201545787. Epub 2015 Dec 29.

19.

Normalization of circulating microRNA expression data obtained by quantitative real-time RT-PCR.

Marabita F, de Candia P, Torri A, Tegnér J, Abrignani S, Rossi RL.

Brief Bioinform. 2016 Mar;17(2):204-12. doi: 10.1093/bib/bbv056. Epub 2015 Aug 3.

20.

Serum microRNAs as Biomarkers of Human Lymphocyte Activation in Health and Disease.

de Candia P, Torri A, Pagani M, Abrignani S.

Front Immunol. 2014 Feb 10;5:43. doi: 10.3389/fimmu.2014.00043. eCollection 2014. Review.

21.

Intracellular modulation, extracellular disposal and serum increase of MiR-150 mark lymphocyte activation.

de Candia P, Torri A, Gorletta T, Fedeli M, Bulgheroni E, Cheroni C, Marabita F, Crosti M, Moro M, Pariani E, Romanò L, Esposito S, Mosca F, Rossetti G, Rossi RL, Geginat J, Casorati G, Dellabona P, Pagani M, Abrignani S.

PLoS One. 2013 Sep 26;8(9):e75348. doi: 10.1371/journal.pone.0075348. eCollection 2013.

22.

Large oncosomes mediate intercellular transfer of functional microRNA.

Morello M, Minciacchi VR, de Candia P, Yang J, Posadas E, Kim H, Griffiths D, Bhowmick N, Chung LW, Gandellini P, Freeman MR, Demichelis F, Di Vizio D.

Cell Cycle. 2013 Nov 15;12(22):3526-36. doi: 10.4161/cc.26539. Epub 2013 Sep 23.

23.

Role of microRNAs and long-non-coding RNAs in CD4(+) T-cell differentiation.

Pagani M, Rossetti G, Panzeri I, de Candia P, Bonnal RJ, Rossi RL, Geginat J, Abrignani S.

Immunol Rev. 2013 May;253(1):82-96. doi: 10.1111/imr.12055. Review.

PMID:
23550640
24.

Nutritional limitation sensitizes mammalian cells to GSK-3β inhibitors and leads to growth impairment.

de Candia P, Minopoli G, Verga V, Gargiulo A, Vanoni M, Alberghina L.

Am J Pathol. 2011 Apr;178(4):1814-23. doi: 10.1016/j.ajpath.2010.12.047.

25.

Copy number variation of CCL3-like genes affects rate of progression to simian-AIDS in Rhesus Macaques (Macaca mulatta).

Degenhardt JD, de Candia P, Chabot A, Schwartz S, Henderson L, Ling B, Hunter M, Jiang Z, Palermo RE, Katze M, Eichler EE, Ventura M, Rogers J, Marx P, Gilad Y, Bustamante CD.

PLoS Genet. 2009 Jan;5(1):e1000346. doi: 10.1371/journal.pgen.1000346. Epub 2009 Jan 23.

26.

A combination of genomic approaches reveals the role of FOXO1a in regulating an oxidative stress response pathway.

de Candia P, Blekhman R, Chabot AE, Oshlack A, Gilad Y.

PLoS One. 2008 Feb 27;3(2):e1670. doi: 10.1371/journal.pone.0001670.

27.

Peptide-conjugated antisense oligonucleotides for targeted inhibition of a transcriptional regulator in vivo.

Henke E, Perk J, Vider J, de Candia P, Chin Y, Solit DB, Ponomarev V, Cartegni L, Manova K, Rosen N, Benezra R.

Nat Biotechnol. 2008 Jan;26(1):91-100. doi: 10.1038/nbt1366. Epub 2008 Jan 6.

PMID:
18176556
28.

ID genes mediate tumor reinitiation during breast cancer lung metastasis.

Gupta GP, Perk J, Acharyya S, de Candia P, Mittal V, Todorova-Manova K, Gerald WL, Brogi E, Benezra R, Massagué J.

Proc Natl Acad Sci U S A. 2007 Dec 4;104(49):19506-11. Epub 2007 Nov 28.

29.

Reassessment of id1 protein expression in human mammary, prostate, and bladder cancers using a monospecific rabbit monoclonal anti-id1 antibody.

Perk J, Gil-Bazo I, Chin Y, de Candia P, Chen JJ, Zhao Y, Chao S, Cheong W, Ke Y, Al-Ahmadie H, Gerald WL, Brogi E, Benezra R.

Cancer Res. 2006 Nov 15;66(22):10870-7.

30.

Induction of complete regressions of oncogene-induced breast tumors in mice.

Benezra R, Henke E, Ciarrocchi A, Ruzinova M, Solit D, Rosen N, Nolan D, Mittal V, de Candia P.

Cold Spring Harb Symp Quant Biol. 2005;70:375-81.

PMID:
16869774
31.

Id4 messenger RNA and estrogen receptor expression: inverse correlation in human normal breast epithelium and carcinoma.

de Candia P, Akram M, Benezra R, Brogi E.

Hum Pathol. 2006 Aug;37(8):1032-41. Epub 2006 May 22.

PMID:
16867866
32.

A role for Id proteins in mammary gland physiology and tumorigenesis.

de Candia P, Benera R, Solit DB.

Adv Cancer Res. 2004;92:81-94. Review.

PMID:
15530557
33.

Angiogenesis impairment in Id-deficient mice cooperates with an Hsp90 inhibitor to completely suppress HER2/neu-dependent breast tumors.

de Candia P, Solit DB, Giri D, Brogi E, Siegel PM, Olshen AB, Muller WJ, Rosen N, Benezra R.

Proc Natl Acad Sci U S A. 2003 Oct 14;100(21):12337-42. Epub 2003 Oct 2.

34.

A genetic approach to understanding tumor angiogenesis.

Benezra R, de Candia P, Li H, Romero E, Lyden D, Rafii S, Ruzinova M.

Cold Spring Harb Symp Quant Biol. 2002;67:249-54. No abstract available.

PMID:
12858547
35.

Id-1 is not expressed in the luminal epithelial cells of mammary glands.

Uehara N, Chou YC, Galvez JJ, de-Candia P, Cardiff RD, Benezra R, Shyamala G.

Breast Cancer Res. 2003;5(2):R25-9. Epub 2003 Jan 9.

36.

The beta-amyloid precursor protein functions as a cytosolic anchoring site that prevents Fe65 nuclear translocation.

Minopoli G, de Candia P, Bonetti A, Faraonio R, Zambrano N, Russo T.

J Biol Chem. 2001 Mar 2;276(9):6545-50. Epub 2000 Nov 20.

37.

Proteins implicated in Alzheimer disease. The role of FE65, a new adapter which binds to beta-amyloid precursor protein.

Ermekova KS, Chang A, Zambrano N, de Candia P, Russo T, Sudol M.

Adv Exp Med Biol. 1998;446:161-80. Review. No abstract available.

PMID:
10079843
38.

Fe65 and the protein network centered around the cytosolic domain of the Alzheimer's beta-amyloid precursor protein.

Russo T, Faraonio R, Minopoli G, De Candia P, De Renzis S, Zambrano N.

FEBS Lett. 1998 Aug 28;434(1-2):1-7. Review.

39.

The Fe65 adaptor protein interacts through its PID1 domain with the transcription factor CP2/LSF/LBP1.

Zambrano N, Minopoli G, de Candia P, Russo T.

J Biol Chem. 1998 Aug 7;273(32):20128-33.

40.

Interaction of the phosphotyrosine interaction/phosphotyrosine binding-related domains of Fe65 with wild-type and mutant Alzheimer's beta-amyloid precursor proteins.

Zambrano N, Buxbaum JD, Minopoli G, Fiore F, De Candia P, De Renzis S, Faraonio R, Sabo S, Cheetham J, Sudol M, Russo T.

J Biol Chem. 1997 Mar 7;272(10):6399-405.

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