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Items: 1 to 50 of 87

1.

Capillary rarefaction is more closely associated with CKD progression after cisplatin, rhabdomyolysis, and ischemia-reperfusion-induced AKI than renal fibrosis.

Menshikh A, Scarfe L, Delgado R, Finney C, Zhu Y, Yang H, de Caestecker MP.

Am J Physiol Renal Physiol. 2019 Nov 1;317(5):F1383-F1397. doi: 10.1152/ajprenal.00366.2019. Epub 2019 Sep 11.

PMID:
31509009
2.

Long-term outcomes in mouse models of ischemia-reperfusion-induced acute kidney injury.

Scarfe L, Menshikh A, Newton E, Zhu Y, Delgado R, Finney C, de Caestecker MP.

Am J Physiol Renal Physiol. 2019 Oct 1;317(4):F1068-F1080. doi: 10.1152/ajprenal.00305.2019. Epub 2019 Aug 14.

PMID:
31411074
3.

The Extracellular Matrix Receptor Discoidin Domain Receptor 1 Regulates Collagen Transcription by Translocating to the Nucleus.

Chiusa M, Hu W, Liao HJ, Su Y, Borza CM, de Caestecker MP, Skrypnyk NI, Fogo AB, Pedchenko V, Li X, Zhang MZ, Hudson BG, Basak T, Vanacore RM, Zent R, Pozzi A.

J Am Soc Nephrol. 2019 Sep;30(9):1605-1624. doi: 10.1681/ASN.2018111160. Epub 2019 Aug 5.

PMID:
31383731
4.

Cell-free hemoglobin augments acute kidney injury during experimental sepsis.

Shaver CM, Paul MG, Putz ND, Landstreet SR, Kuck JL, Scarfe L, Skrypnyk N, Yang H, Harrison FE, de Caestecker MP, Bastarache JA, Ware LB.

Am J Physiol Renal Physiol. 2019 Oct 1;317(4):F922-F929. doi: 10.1152/ajprenal.00375.2018. Epub 2019 Jul 31.

PMID:
31364379
5.

Sepsis-Associated Acute Kidney Injury: A Problem Deserving of New Solutions.

Kellum JA, Wen X, de Caestecker MP, Hukriede NA.

Nephron. 2019;143(3):174-178. doi: 10.1159/000500167. Epub 2019 Apr 24. Review.

6.

Low-grade albuminuria in pulmonary arterial hypertension.

Nickel NP, de Jesus Perez VA, Zamanian RT, Fessel JP, Cogan JD, Hamid R, West JD, de Caestecker MP, Yang H, Austin ED.

Pulm Circ. 2019 Apr-Jun;9(2):2045894018824564. doi: 10.1177/2045894018824564.

7.

Transdermal Measurement of Glomerular Filtration Rate in Mice.

Scarfe L, Schock-Kusch D, Ressel L, Friedemann J, Shulhevich Y, Murray P, Wilm B, de Caestecker M.

J Vis Exp. 2018 Oct 21;(140). doi: 10.3791/58520.

8.

Overcoming Translational Barriers in Acute Kidney Injury: A Report from an NIDDK Workshop.

Zuk A, Palevsky PM, Fried L, Harrell FE Jr, Khan S, McKay DB, Devey L, Chawla L, de Caestecker M, Kaufman JS, Thompson BT, Agarwal A, Greene T, Okusa MD, Bonventre JV, Dember LM, Liu KD, Humphreys BD, Gossett D, Xie Y, Norton JM, Kimmel PL, Star RA.

Clin J Am Soc Nephrol. 2018 Jul 6;13(7):1113-1123. doi: 10.2215/CJN.06820617. Epub 2018 Mar 9.

9.

BMPR2 mutations and endothelial dysfunction in pulmonary arterial hypertension (2017 Grover Conference Series).

Frump A, Prewitt A, de Caestecker MP.

Pulm Circ. 2018 Apr-Jun;8(2):2045894018765840. doi: 10.1177/2045894018765840. Epub 2018 Mar 9.

10.

Translating Knowledge Into Therapy for Acute Kidney Injury.

de Caestecker M, Harris R.

Semin Nephrol. 2018 Jan;38(1):88-97. doi: 10.1016/j.semnephrol.2017.09.008. Review.

11.

Drug Discovery to Halt the Progression of Acute Kidney Injury to Chronic Kidney Disease: A Case for Phenotypic Drug Discovery in Acute Kidney Injury.

Hukriede N, Vogt A, de Caestecker M.

Nephron. 2017;137(4):268-272. doi: 10.1159/000476079. Epub 2017 Jun 15. Review.

12.

Genotype-phenotype effects of Bmpr2 mutations on disease severity in mouse models of pulmonary hypertension.

Frump AL, Datta A, Ghose S, West J, de Caestecker MP.

Pulm Circ. 2016 Dec;6(4):597-607. doi: 10.1086/688930.

13.

Correction: Deletion of Fibroblast Growth Factor Receptor 2 from the Peri-Wolffian Duct Stroma Leads to Ureteric Induction Abnormalities and Vesicoureteral Reflux.

Walker KA, Sims-Lucas S, Di Giovanni VE, Schaefer C, Sunseri WM, Novitskaya T, de Caestecker MP, Chen F, Bates CM.

PLoS One. 2016 Nov 18;11(11):e0167191. doi: 10.1371/journal.pone.0167191. eCollection 2016.

14.

Reply to "Bone morphogenetic protein's contribution to pulmonary artery hypertension".

King T, de Caestecker M, Lowery JW.

Surg Neurol Int. 2016 Oct 19;7:91. eCollection 2016. No abstract available.

15.

Antagonism of the thromboxane-prostanoid receptor is cardioprotective against right ventricular pressure overload.

West JD, Voss BM, Pavliv L, de Caestecker M, Hemnes AR, Carrier EJ.

Pulm Circ. 2016 Jun;6(2):211-23. doi: 10.1086/686140.

16.

Pyridoxamine reduces postinjury fibrosis and improves functional recovery after acute kidney injury.

Skrypnyk NI, Voziyan P, Yang H, de Caestecker CR, Theberge MC, Drouin M, Hudson B, Harris RC, de Caestecker MP.

Am J Physiol Renal Physiol. 2016 Aug 1;311(2):F268-77. doi: 10.1152/ajprenal.00056.2016. Epub 2016 May 18.

17.

Bridging translation for acute kidney injury with better preclinical modeling of human disease.

Skrypnyk NI, Siskind LJ, Faubel S, de Caestecker MP.

Am J Physiol Renal Physiol. 2016 May 15;310(10):F972-84. doi: 10.1152/ajprenal.00552.2015. Epub 2016 Mar 9. Review.

18.

Delayed treatment with PTBA analogs reduces postinjury renal fibrosis after kidney injury.

Skrypnyk NI, Sanker S, Skvarca LB, Novitskaya T, Woods C, Chiba T, Patel K, Goldberg ND, McDermott L, Vinson PN, Calcutt MW, Huryn DM, Vernetti LA, Vogt A, Hukriede NA, de Caestecker MP.

Am J Physiol Renal Physiol. 2016 Apr 15;310(8):F705-F716. doi: 10.1152/ajprenal.00503.2015. Epub 2015 Dec 9.

19.

Bridging Translation by Improving Preclinical Study Design in AKI.

de Caestecker M, Humphreys BD, Liu KD, Fissell WH, Cerda J, Nolin TD, Askenazi D, Mour G, Harrell FE Jr, Pullen N, Okusa MD, Faubel S; ASN AKI Advisory Group.

J Am Soc Nephrol. 2015 Dec;26(12):2905-16. doi: 10.1681/ASN.2015070832. Epub 2015 Nov 4. Review.

20.

Kidney Regeneration: Lessons from Development.

Chiba T, Hukriede N, de Caestecker MP.

Curr Pathobiol Rep. 2015 Mar;3(1):67-79.

21.

Retinoic Acid Signaling Coordinates Macrophage-Dependent Injury and Repair after AKI.

Chiba T, Skrypnyk NI, Skvarca LB, Penchev R, Zhang KX, Rochon ER, Fall JL, Paueksakon P, Yang H, Alford CE, Roman BL, Zhang MZ, Harris R, Hukriede NA, de Caestecker MP.

J Am Soc Nephrol. 2016 Feb;27(2):495-508. doi: 10.1681/ASN.2014111108. Epub 2015 Jun 24.

22.

Zebrafish Models of Kidney Damage and Repair.

Cirio MC, de Caestecker MP, Hukriede NA.

Curr Pathobiol Rep. 2015 Jun;3(2):163-170. doi: 10.1007/s40139-015-0080-4. Epub 2015 Apr 11.

23.

SIX2 Effects on Wilms Tumor Biology.

Pierce J, Murphy AJ, Panzer A, de Caestecker C, Ayers GD, Neblett D, Saito-Diaz K, de Caestecker M, Lovvorn HN 3rd.

Transl Oncol. 2014 Dec;7(6):800-11. doi: 10.1016/j.tranon.2014.09.005.

24.

Heterozygous null bone morphogenetic protein receptor type 2 mutations promote SRC kinase-dependent caveolar trafficking defects and endothelial dysfunction in pulmonary arterial hypertension.

Prewitt AR, Ghose S, Frump AL, Datta A, Austin ED, Kenworthy AK, de Caestecker MP.

J Biol Chem. 2015 Jan 9;290(2):960-71. doi: 10.1074/jbc.M114.591057. Epub 2014 Nov 19.

25.

CITED1 confers stemness to Wilms tumor and enhances tumorigenic responses when enriched in the nucleus.

Murphy AJ, Pierce J, de Caestecker C, Ayers GD, Zhao A, Krebs JR, Saito-Diaz VK, Lee E, Perantoni AO, de Caestecker MP, Lovvorn HN 3rd.

Oncotarget. 2014 Jan 30;5(2):386-402.

26.

A PTBA small molecule enhances recovery and reduces postinjury fibrosis after aristolochic acid-induced kidney injury.

Novitskaya T, McDermott L, Zhang KX, Chiba T, Paueksakon P, Hukriede NA, de Caestecker MP.

Am J Physiol Renal Physiol. 2014 Mar 1;306(5):F496-504. doi: 10.1152/ajprenal.00534.2013. Epub 2013 Dec 26.

27.

Abnormal trafficking of endogenously expressed BMPR2 mutant allelic products in patients with heritable pulmonary arterial hypertension.

Frump AL, Lowery JW, Hamid R, Austin ED, de Caestecker M.

PLoS One. 2013 Nov 5;8(11):e80319. doi: 10.1371/journal.pone.0080319. eCollection 2013.

28.

Aberrant activation, nuclear localization, and phosphorylation of Yes-associated protein-1 in the embryonic kidney and Wilms tumor.

Murphy AJ, Pierce J, de Caestecker C, Libes J, Neblett D, de Caestecker M, Perantoni AO, Tanigawa S, Anderson JR, Dome JS, Das A, Carroll TJ, Lovvorn HN 3rd.

Pediatr Blood Cancer. 2014 Feb;61(2):198-205. doi: 10.1002/pbc.24788. Epub 2013 Sep 20.

29.

Kidney regeneration: common themes from the embryo to the adult.

Cirio MC, de Groh ED, de Caestecker MP, Davidson AJ, Hukriede NA.

Pediatr Nephrol. 2014 Apr;29(4):553-64. doi: 10.1007/s00467-013-2597-2. Epub 2013 Sep 5. Review.

30.

Ischemia-reperfusion model of acute kidney injury and post injury fibrosis in mice.

Skrypnyk NI, Harris RC, de Caestecker MP.

J Vis Exp. 2013 Aug 9;(78). doi: 10.3791/50495.

31.

Histone deacetylase inhibitor enhances recovery after AKI.

Cianciolo Cosentino C, Skrypnyk NI, Brilli LL, Chiba T, Novitskaya T, Woods C, West J, Korotchenko VN, McDermott L, Day BW, Davidson AJ, Harris RC, de Caestecker MP, Hukriede NA.

J Am Soc Nephrol. 2013 May;24(6):943-53. doi: 10.1681/ASN.2012111055. Epub 2013 Apr 25.

32.

Deletion of fibroblast growth factor receptor 2 from the peri-wolffian duct stroma leads to ureteric induction abnormalities and vesicoureteral reflux.

Walker KA, Sims-Lucas S, Di Giovanni VE, Schaefer C, Sunseri WM, Novitskaya T, de Caestecker MP, Chen F, Bates CM.

PLoS One. 2013;8(2):e56062. doi: 10.1371/journal.pone.0056062. Epub 2013 Feb 7. Erratum in: PLoS One. 2016 Nov 18;11(11):e0167191.

33.

CITED1 expression in liver development and hepatoblastoma.

Murphy AJ, de Caestecker C, Pierce J, Boyle SC, Ayers GD, Zhao Z, Libes JM, Correa H, Walter T, Huppert SS, Perantoni AO, de Caestecker MP, Lovvorn HN 3rd.

Neoplasia. 2012 Dec;14(12):1153-63.

34.

HDAC inhibitors in kidney development and disease.

Brilli LL, Swanhart LM, de Caestecker MP, Hukriede NA.

Pediatr Nephrol. 2013 Oct;28(10):1909-21. doi: 10.1007/s00467-012-2320-8. Epub 2012 Oct 7. Review.

35.

SIX2 and CITED1, markers of nephronic progenitor self-renewal, remain active in primitive elements of Wilms' tumor.

Murphy AJ, Pierce J, de Caestecker C, Taylor C, Anderson JR, Perantoni AO, de Caestecker MP, Lovvorn HN 3rd.

J Pediatr Surg. 2012 Jun;47(6):1239-49. doi: 10.1016/j.jpedsurg.2012.03.034.

36.

Ischemia-reperfusion injury of the mouse kidney.

Oxburgh L, de Caestecker MP.

Methods Mol Biol. 2012;886:363-79. doi: 10.1007/978-1-61779-851-1_32.

PMID:
22639277
37.

Molecular characterization of Wilms' tumor from a resource-constrained region of sub-Saharan Africa.

Murphy AJ, Axt JR, de Caestecker C, Pierce J, Correa H, Seeley EH, Caprioli RM, Newton MW, de Caestecker MP, Lovvorn HN 3rd.

Int J Cancer. 2012 Sep 15;131(6):E983-94. doi: 10.1002/ijc.27544. Epub 2012 Apr 4.

38.

FGF/EGF signaling regulates the renewal of early nephron progenitors during embryonic development.

Brown AC, Adams D, de Caestecker M, Yang X, Friesel R, Oxburgh L.

Development. 2011 Dec;138(23):5099-112. doi: 10.1242/dev.065995. Epub 2011 Oct 26.

39.

β-Catenin and K-RAS synergize to form primitive renal epithelial tumors with features of epithelial Wilms' tumors.

Clark PE, Polosukhina D, Love H, Correa H, Coffin C, Perlman EJ, de Caestecker M, Moses HL, Zent R.

Am J Pathol. 2011 Dec;179(6):3045-55. doi: 10.1016/j.ajpath.2011.08.006. Epub 2011 Oct 8.

40.

Zebrafish kidney development: basic science to translational research.

Swanhart LM, Cosentino CC, Diep CQ, Davidson AJ, de Caestecker M, Hukriede NA.

Birth Defects Res C Embryo Today. 2011 Jun;93(2):141-56. doi: 10.1002/bdrc.20209. Review.

41.

Organ-specific defects in insulin-like growth factor and insulin receptor signaling in late gestational asymmetric intrauterine growth restriction in Cited1 mutant mice.

Novitskaya T, Baserga M, de Caestecker MP.

Endocrinology. 2011 Jun;152(6):2503-16. doi: 10.1210/en.2010-1385. Epub 2011 Apr 12.

42.

ID family protein expression and regulation in hypoxic pulmonary hypertension.

Lowery JW, Frump AL, Anderson L, DiCarlo GE, Jones MT, de Caestecker MP.

Am J Physiol Regul Integr Comp Physiol. 2010 Dec;299(6):R1463-77. doi: 10.1152/ajpregu.00866.2009. Epub 2010 Sep 29.

43.

BMP signaling in vascular development and disease.

Lowery JW, de Caestecker MP.

Cytokine Growth Factor Rev. 2010 Aug;21(4):287-98. doi: 10.1016/j.cytogfr.2010.06.001. Epub 2010 Jul 31. Review.

44.

Bmp2 and Bmp4 exert opposing effects in hypoxic pulmonary hypertension.

Anderson L, Lowery JW, Frank DB, Novitskaya T, Jones M, Mortlock DP, Chandler RL, de Caestecker MP.

Am J Physiol Regul Integr Comp Physiol. 2010 Mar;298(3):R833-42. doi: 10.1152/ajpregu.00534.2009. Epub 2009 Dec 30.

45.

Placental insufficiency associated with loss of Cited1 causes renal medullary dysplasia.

Sparrow DB, Boyle SC, Sams RS, Mazuruk B, Zhang L, Moeckel GW, Dunwoodie SL, de Caestecker MP.

J Am Soc Nephrol. 2009 Apr;20(4):777-86. doi: 10.1681/ASN.2008050547. Epub 2009 Mar 18.

46.

NFATc1 identifies a population of proximal tubule cell progenitors.

Langworthy M, Zhou B, de Caestecker M, Moeckel G, Baldwin HS.

J Am Soc Nephrol. 2009 Feb;20(2):311-21. doi: 10.1681/ASN.2008010094. Epub 2008 Dec 31.

47.

Fate mapping using Cited1-CreERT2 mice demonstrates that the cap mesenchyme contains self-renewing progenitor cells and gives rise exclusively to nephronic epithelia.

Boyle S, Misfeldt A, Chandler KJ, Deal KK, Southard-Smith EM, Mortlock DP, Baldwin HS, de Caestecker M.

Dev Biol. 2008 Jan 1;313(1):234-45. Epub 2007 Oct 24.

48.

Increased susceptibility to hypoxic pulmonary hypertension in Bmpr2 mutant mice is associated with endothelial dysfunction in the pulmonary vasculature.

Frank DB, Lowery J, Anderson L, Brink M, Reese J, de Caestecker M.

Am J Physiol Lung Cell Mol Physiol. 2008 Jan;294(1):L98-109. Epub 2007 Nov 16.

49.

CITED1 expression in Wilms' tumor and embryonic kidney.

Lovvorn HN, Westrup J, Opperman S, Boyle S, Shi G, Anderson J, Perlman EJ, Perantoni AO, Wills M, de Caestecker M.

Neoplasia. 2007 Jul;9(7):589-600.

50.

Angiopoietin-2 and glomerular proteinuria.

de Caestecker MP.

J Am Soc Nephrol. 2007 Aug;18(8):2217-8. Epub 2007 Jul 11. No abstract available.

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