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Items: 1 to 50 of 248

1.

Hypoxia negatively affects senescence in osteoclasts and delays osteoclastogenesis.

Gorissen B, de Bruin A, Miranda-Bedate A, Korthagen N, Wolschrijn C, de Vries TJ, van Weeren R, Tryfonidou MA.

J Cell Physiol. 2018 Jun 22. doi: 10.1002/jcp.26511. [Epub ahead of print]

PMID:
29932209
2.

Reduced expression of C/EBPβ-LIP extends health and lifespan in mice.

Müller C, Zidek LM, Ackermann T, de Jong T, Liu P, Kliche V, Zaini MA, Kortman G, Harkema L, Verbeek DS, Tuckermann JP, von Maltzahn J, de Bruin A, Guryev V, Wang ZQ, Calkhoven CF.

Elife. 2018 Jun 4;7. pii: e34985. doi: 10.7554/eLife.34985.

3.

A lifelong study of a pack Rhodesian ridgeback dogs reveals subclinical and clinical tick-borne Anaplasma phagocytophilum infections with possible reinfection or persistence.

Hovius E, de Bruin A, Schouls L, Hovius J, Dekker N, Sprong H.

Parasit Vectors. 2018 Apr 12;11(1):238. doi: 10.1186/s13071-018-2806-8.

4.

Is there a superior simulator for human anatomy education? How virtual dissection can overcome the anatomic and pedagogic limitations of cadaveric dissection.

Darras KE, de Bruin ABH, Nicolaou S, Dahlström N, Persson A, van Merriënboer J, Forster BB.

Med Teach. 2018 Mar 23:1-2. doi: 10.1080/0142159X.2018.1451629. [Epub ahead of print]

PMID:
29569960
5.

Is bilingualism associated with enhanced executive functioning in adults? A meta-analytic review.

Lehtonen M, Soveri A, Laine A, Järvenpää J, de Bruin A, Antfolk J.

Psychol Bull. 2018 Apr;144(4):394-425. doi: 10.1037/bul0000142. Epub 2018 Mar 1.

PMID:
29494195
6.

Assessing bat droppings and predatory bird pellets for vector-borne bacteria: molecular evidence of bat-associated Neorickettsia sp. in Europe.

Hornok S, Szőke K, Estók P, Krawczyk A, Haarsma AJ, Kováts D, Boldogh SA, Morandini P, Szekeres S, Takács N, Kontschán J, Meli ML, Fernández de Mera IG, de la Fuente J, Gyuranecz M, Sulyok KM, Weibel B, Gönczi E, de Bruin A, Sprong H, Hofmann-Lehmann R.

Antonie Van Leeuwenhoek. 2018 Feb 28. doi: 10.1007/s10482-018-1043-7. [Epub ahead of print]

PMID:
29492770
7.

Chk1 and 14-3-3 proteins inhibit atypical E2Fs to prevent a permanent cell cycle arrest.

Yuan R, Vos HR, van Es RM, Chen J, Burgering BM, Westendorp B, de Bruin A.

EMBO J. 2018 Mar 1;37(5). pii: e97877. doi: 10.15252/embj.201797877. Epub 2018 Jan 23.

8.

Atypical E2f functions are critical for pancreas polyploidization.

Matondo RB, Moreno E, Toussaint MJM, Tooten PCJ, van Essen SC, van Liere EA, Youssef SA, Bongiovanni L, de Bruin A.

PLoS One. 2018 Jan 12;13(1):e0190899. doi: 10.1371/journal.pone.0190899. eCollection 2018.

9.

DYRK1A Is a Regulator of S-Phase Entry in Hepatic Progenitor Cells.

Kruitwagen HS, Westendorp B, Viebahn CS, Post K, van Wolferen ME, Oosterhoff LA, Egan DA, Delabar JM, Toussaint MJ, Schotanus BA, de Bruin A, Rothuizen J, Penning LC, Spee B.

Stem Cells Dev. 2018 Jan 15;27(2):133-146. doi: 10.1089/scd.2017.0139. Epub 2018 Jan 3.

PMID:
29179659
10.

Pathogen communities of songbird-derived ticks in Europe's low countries.

Heylen D, Fonville M, Docters van Leeuwen A, Stroo A, Duisterwinkel M, van Wieren S, Diuk-Wasser M, de Bruin A, Sprong H.

Parasit Vectors. 2017 Oct 18;10(1):497. doi: 10.1186/s13071-017-2423-y.

11.

Intraductal cisplatin treatment in a BRCA-associated breast cancer mouse model attenuates tumor development but leads to systemic tumors in aged female mice.

de Groot JS, van Diest PJ, van Amersfoort M, Vlug EJ, Pan X, Ter Hoeve ND, Rosing H, Beijnen JH, Youssef SA, de Bruin A, Jonkers J, van der Wall E, Derksen PWB.

Oncotarget. 2017 Jun 15;8(37):60750-60763. doi: 10.18632/oncotarget.18490. eCollection 2017 Sep 22.

12.

Atypical E2Fs inhibit tumor angiogenesis.

Weijts BGMW, Westendorp B, Hien BT, Martínez-López LM, Zijp M, Thurlings I, Thomas RE, Schulte-Merker S, Bakker WJ, de Bruin A.

Oncogene. 2018 Jan 11;37(2):271-276. doi: 10.1038/onc.2017.336. Epub 2017 Sep 18.

13.

CDK10 Mutations in Humans and Mice Cause Severe Growth Retardation, Spine Malformations, and Developmental Delays.

Windpassinger C, Piard J, Bonnard C, Alfadhel M, Lim S, Bisteau X, Blouin S, Ali NB, Ng AYJ, Lu H, Tohari S, Talib SZA, van Hul N, Caldez MJ, Van Maldergem L, Yigit G, Kayserili H, Youssef SA, Coppola V, de Bruin A, Tessarollo L, Choi H, Rupp V, Roetzer K, Roschger P, Klaushofer K, Altmüller J, Roy S, Venkatesh B, Ganger R, Grill F, Ben Chehida F, Wollnik B, Altunoglu U, Al Kaissi A, Reversade B, Kaldis P.

Am J Hum Genet. 2017 Sep 7;101(3):391-403. doi: 10.1016/j.ajhg.2017.08.003.

14.

Athletes with eating disorder symptomatology, a specific population with specific needs.

de Bruin APK.

Curr Opin Psychol. 2017 Aug;16:148-153. doi: 10.1016/j.copsyc.2017.05.009. Epub 2017 Jun 4. Review.

PMID:
28813340
15.

Effects of age on inhibitory control are affected by task-specific features.

de Bruin A, Sala SD.

Q J Exp Psychol (Hove). 2018 May;71(5):1219-1233. doi: 10.1080/17470218.2017.1311352. Epub 2018 Jan 1.

PMID:
28776486
16.

NF-κB p65 serine 467 phosphorylation sensitizes mice to weight gain and TNFα-or diet-induced inflammation.

Riedlinger T, Dommerholt MB, Wijshake T, Kruit JK, Huijkman N, Dekker D, Koster M, Kloosterhuis N, Koonen DPY, de Bruin A, Baker D, Hofker MH, van Deursen J, Jonker JW, Schmitz ML, van de Sluis B.

Biochim Biophys Acta. 2017 Oct;1864(10):1785-1798. doi: 10.1016/j.bbamcr.2017.07.005. Epub 2017 Jul 16.

PMID:
28723419
17.

Differential requirements for Tousled-like kinases 1 and 2 in mammalian development.

Segura-Bayona S, Knobel PA, González-Burón H, Youssef SA, Peña-Blanco A, Coyaud É, López-Rovira T, Rein K, Palenzuela L, Colombelli J, Forrow S, Raught B, Groth A, de Bruin A, Stracker TH.

Cell Death Differ. 2017 Nov;24(11):1872-1885. doi: 10.1038/cdd.2017.108. Epub 2017 Jul 14.

PMID:
28708136
18.

The BEST Dataset of Language Proficiency.

de Bruin A, Carreiras M, Duñabeitia JA.

Front Psychol. 2017 Apr 6;8:522. doi: 10.3389/fpsyg.2017.00522. eCollection 2017. No abstract available.

19.

Monitoring and regulation of learning in medical education: the need for predictive cues.

de Bruin ABH, Dunlosky J, Cavalcanti RB.

Med Educ. 2017 Jun;51(6):575-584. doi: 10.1111/medu.13267. Epub 2017 Mar 23. Review.

20.

Why are children overconfident? Developmental differences in the implementation of accessibility cues when judging concept learning.

van Loon M, de Bruin A, Leppink J, Roebers C.

J Exp Child Psychol. 2017 Jun;158:77-94. doi: 10.1016/j.jecp.2017.01.008. Epub 2017 Feb 23.

PMID:
28236719
21.

Dosage-dependent copy number gains in E2f1 and E2f3 drive hepatocellular carcinoma.

Kent LN, Bae S, Tsai SY, Tang X, Srivastava A, Koivisto C, Martin CK, Ridolfi E, Miller GC, Zorko SM, Plevris E, Hadjiyannis Y, Perez M, Nolan E, Kladney R, Westendorp B, de Bruin A, Fernandez S, Rosol TJ, Pohar KS, Pipas JM, Leone G.

J Clin Invest. 2017 Mar 1;127(3):830-842. doi: 10.1172/JCI87583. Epub 2017 Jan 30.

22.

Modeling Dynamics and Function of Bone Marrow Cells in Mouse Liver Regeneration.

Pedone E, Olteanu VA, Marucci L, Muñoz-Martin MI, Youssef SA, de Bruin A, Cosma MP.

Cell Rep. 2017 Jan 3;18(1):107-121. doi: 10.1016/j.celrep.2016.12.008.

23.

Aberrantly expressed LGR4 empowers Wnt signaling in multiple myeloma by hijacking osteoblast-derived R-spondins.

van Andel H, Ren Z, Koopmans I, Joosten SP, Kocemba KA, de Lau W, Kersten MJ, de Bruin AM, Guikema JE, Clevers H, Spaargaren M, Pals ST.

Proc Natl Acad Sci U S A. 2017 Jan 10;114(2):376-381. doi: 10.1073/pnas.1618650114. Epub 2016 Dec 27.

24.

Functional role of CCL5/RANTES for HCC progression during chronic liver disease.

Mohs A, Kuttkat N, Reißing J, Zimmermann HW, Sonntag R, Proudfoot A, Youssef SA, de Bruin A, Cubero FJ, Trautwein C.

J Hepatol. 2017 Apr;66(4):743-753. doi: 10.1016/j.jhep.2016.12.011. Epub 2016 Dec 21.

PMID:
28011329
25.

The challenges of studying visual expertise in medical image diagnosis.

Gegenfurtner A, Kok E, van Geel K, de Bruin A, Jarodzka H, Szulewski A, van Merriënboer JJ.

Med Educ. 2017 Jan;51(1):97-104. doi: 10.1111/medu.13205.

PMID:
27981656
26.

Cellular Senescence Promotes Adverse Effects of Chemotherapy and Cancer Relapse.

Demaria M, O'Leary MN, Chang J, Shao L, Liu S, Alimirah F, Koenig K, Le C, Mitin N, Deal AM, Alston S, Academia EC, Kilmarx S, Valdovinos A, Wang B, de Bruin A, Kennedy BK, Melov S, Zhou D, Sharpless NE, Muss H, Campisi J.

Cancer Discov. 2017 Feb;7(2):165-176. doi: 10.1158/2159-8290.CD-16-0241. Epub 2016 Dec 15.

27.

The potential of neuroscience for health sciences education: towards convergence of evidence and resisting seductive allure.

de Bruin ABH.

Adv Health Sci Educ Theory Pract. 2016 Dec;21(5):983-990. doi: 10.1007/s10459-016-9733-2. Epub 2016 Nov 7.

28.

Through rose-coloured glasses: An empirical test of narcissistic overestimation.

Lobbestael J, de Bruin A, Kok E, Voncken M.

Personal Ment Health. 2016 Nov;10(4):305-316. doi: 10.1002/pmh.1347. Epub 2016 Jul 13.

PMID:
27406650
29.

Use of an Image Acquisition Stabilizer Improves Sidestream Dark Field Imaging of the Serosa during Open Gastrointestinal Surgery.

de Bruin AF, Tavy A, van der Sloot K, Smits A, Van Ramshorst B, Boerma CE, Kars P, Noordzij PG, Boerma D, van Iterson M.

J Vasc Res. 2016;53(3-4):121-127. Epub 2016 Oct 4.

PMID:
27698325
30.

The DNA Damage Response Regulates RAG1/2 Expression in Pre-B Cells through ATM-FOXO1 Signaling.

Ochodnicka-Mackovicova K, Bahjat M, Maas C, van der Veen A, Bloedjes TA, de Bruin AM, van Andel H, Schrader CE, Hendriks RW, Verhoeyen E, Bende RJ, van Noesel CJ, Guikema JE.

J Immunol. 2016 Oct 1;197(7):2918-29. doi: 10.4049/jimmunol.1501989. Epub 2016 Aug 24.

31.

Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice.

Vermeij WP, Dollé ME, Reiling E, Jaarsma D, Payan-Gomez C, Bombardieri CR, Wu H, Roks AJ, Botter SM, van der Eerden BC, Youssef SA, Kuiper RV, Nagarajah B, van Oostrom CT, Brandt RM, Barnhoorn S, Imholz S, Pennings JL, de Bruin A, Gyenis Á, Pothof J, Vijg J, van Steeg H, Hoeijmakers JH.

Nature. 2016 Sep 15;537(7620):427-431. doi: 10.1038/nature19329. Epub 2016 Aug 24.

32.

E2f8 mediates tumor suppression in postnatal liver development.

Kent LN, Rakijas JB, Pandit SK, Westendorp B, Chen HZ, Huntington JT, Tang X, Bae S, Srivastava A, Senapati S, Koivisto C, Martin CK, Cuitino MC, Perez M, Clouse JM, Chokshi V, Shinde N, Kladney R, Sun D, Perez-Castro A, Matondo RB, Nantasanti S, Mokry M, Huang K, Machiraju R, Fernandez S, Rosol TJ, Coppola V, Pohar KS, Pipas JM, Schmidt CR, de Bruin A, Leone G.

J Clin Invest. 2016 Aug 1;126(8):2955-69. doi: 10.1172/JCI85506. Epub 2016 Jul 25.

33.

Synergistic functions of E2F7 and E2F8 are critical to suppress stress-induced skin cancer.

Thurlings I, Martínez-López LM, Westendorp B, Zijp M, Kuiper R, Tooten P, Kent LN, Leone G, Vos HJ, Burgering B, de Bruin A.

Oncogene. 2017 Feb 9;36(6):829-839. doi: 10.1038/onc.2016.251. Epub 2016 Jul 25.

34.

Surgical resection and radiofrequency ablation initiate cancer in cytokeratin-19+- liver cells deficient for p53 and Rb.

Matondo RB, Toussaint MJ, Govaert KM, van Vuuren LD, Nantasanti S, Nijkamp MW, Pandit SK, Tooten PC, Koster MH, Holleman K, Schot A, Gu G, Spee B, Roskams T, Rinkes IB, Schotanus B, Kranenburg O, de Bruin A.

Oncotarget. 2016 Aug 23;7(34):54662-54675. doi: 10.18632/oncotarget.9952.

35.

Amplification of R-spondin1 signaling induces granulosa cell fate defects and cancers in mouse adult ovary.

De Cian MC, Pauper E, Bandiera R, Vidal VP, Sacco S, Gregoire EP, Chassot AA, Panzolini C, Wilhelm D, Pailhoux E, Youssef SA, de Bruin A, Teerds K, Schedl A, Gillot I, Chaboissier MC.

Oncogene. 2017 Jan 12;36(2):208-218. doi: 10.1038/onc.2016.191. Epub 2016 Jun 6.

36.

A20 prevents chronic liver inflammation and cancer by protecting hepatocytes from death.

Catrysse L, Farhang Ghahremani M, Vereecke L, Youssef SA, Mc Guire C, Sze M, Weber A, Heikenwalder M, de Bruin A, Beyaert R, van Loo G.

Cell Death Dis. 2016 Jun 2;7(6):e2250. doi: 10.1038/cddis.2016.154.

37.

Compulsive foreign language syndrome: A clinical observation not a mystery.

Beschin N, de Bruin A, Della Sala S.

Cortex. 2016 Aug;81:276-7. doi: 10.1016/j.cortex.2016.04.020. Epub 2016 May 4. No abstract available.

PMID:
27216358
38.

Full ablation of C9orf72 in mice causes immune system-related pathology and neoplastic events but no motor neuron defects.

Sudria-Lopez E, Koppers M, de Wit M, van der Meer C, Westeneng HJ, Zundel CA, Youssef SA, Harkema L, de Bruin A, Veldink JH, van den Berg LH, Pasterkamp RJ.

Acta Neuropathol. 2016 Jul;132(1):145-7. doi: 10.1007/s00401-016-1581-x. Epub 2016 May 20. No abstract available.

39.

Detection of Coxiella burnetii in Ambient Air after a Large Q Fever Outbreak.

de Rooij MM, Borlée F, Smit LA, de Bruin A, Janse I, Heederik DJ, Wouters IM.

PLoS One. 2016 Mar 18;11(3):e0151281. doi: 10.1371/journal.pone.0151281. eCollection 2016.

40.

Rb and p53 Liver Functions Are Essential for Xenobiotic Metabolism and Tumor Suppression.

Nantasanti S, Toussaint MJ, Youssef SA, Tooten PC, de Bruin A.

PLoS One. 2016 Mar 11;11(3):e0150064. doi: 10.1371/journal.pone.0150064. eCollection 2016.

41.

GEMC1 is a critical regulator of multiciliated cell differentiation.

Terré B, Piergiovanni G, Segura-Bayona S, Gil-Gómez G, Youssef SA, Attolini CS, Wilsch-Bräuninger M, Jung C, Rojas AM, Marjanović M, Knobel PA, Palenzuela L, López-Rovira T, Forrow S, Huttner WB, Valverde MA, de Bruin A, Costanzo V, Stracker TH.

EMBO J. 2016 May 2;35(9):942-60. doi: 10.15252/embj.201592821. Epub 2016 Mar 1.

42.

Reverse inference of memory retrieval processes underlying metacognitive monitoring of learning using multivariate pattern analysis.

Stiers P, Falbo L, Goulas A, van Gog T, de Bruin A.

Neuroimage. 2016 May 15;132:11-23. doi: 10.1016/j.neuroimage.2016.02.008. Epub 2016 Feb 13.

PMID:
26883066
43.

Feedback regulation between atypical E2Fs and APC/CCdh1 coordinates cell cycle progression.

Boekhout M, Yuan R, Wondergem AP, Segeren HA, van Liere EA, Awol N, Jansen I, Wolthuis RM, de Bruin A, Westendorp B.

EMBO Rep. 2016 Mar;17(3):414-27. doi: 10.15252/embr.201540984. Epub 2016 Feb 5.

44.

Pathology of Mouse Models of Accelerated Aging.

Harkema L, Youssef SA, de Bruin A.

Vet Pathol. 2016 Mar;53(2):366-89. doi: 10.1177/0300985815625169. Epub 2016 Feb 10. Review.

PMID:
26864891
45.

Effective treatment of steatosis and steatohepatitis by fibroblast growth factor 1 in mouse models of nonalcoholic fatty liver disease.

Liu W, Struik D, Nies VJ, Jurdzinski A, Harkema L, de Bruin A, Verkade HJ, Downes M, Evans RM, van Zutphen T, Jonker JW.

Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):2288-93. doi: 10.1073/pnas.1525093113. Epub 2016 Feb 8.

46.

Concise Review: Organoids Are a Powerful Tool for the Study of Liver Disease and Personalized Treatment Design in Humans and Animals.

Nantasanti S, de Bruin A, Rothuizen J, Penning LC, Schotanus BA.

Stem Cells Transl Med. 2016 Mar;5(3):325-30. doi: 10.5966/sctm.2015-0152. Epub 2016 Jan 21. Review.

47.

Sidestream dark field imaging of the serosal microcirculation during gastrointestinal surgery.

de Bruin AF, Kornmann VN, van der Sloot K, van Vugt JL, Gosselink MP, Smits A, Van Ramshorst B, Boerma EC, Noordzij PG, Boerma D, van Iterson M.

Colorectal Dis. 2016 Mar;18(3):O103-10. doi: 10.1111/codi.13250.

PMID:
26725570
48.

Genome-wide analysis reveals NRP1 as a direct HIF1α-E2F7 target in the regulation of motorneuron guidance in vivo.

de Bruin A, A Cornelissen PW, Kirchmaier BC, Mokry M, Iich E, Nirmala E, Liang KH, D Végh AM, Scholman KT, Groot Koerkamp MJ, Holstege FC, Cuppen E, Schulte-Merker S, Bakker WJ.

Nucleic Acids Res. 2016 May 5;44(8):3549-66. doi: 10.1093/nar/gkv1471. Epub 2015 Dec 17.

49.

Four Common Pitfalls of Quantitative Analysis in Experimental Research.

Leppink J, Kok EM, Bergman EM, van Loon MH, de Bruin AB.

Acad Med. 2016 Jun;91(6):891. doi: 10.1097/ACM.0000000000000946. No abstract available.

PMID:
26466375
50.

Disease Modeling and Gene Therapy of Copper Storage Disease in Canine Hepatic Organoids.

Nantasanti S, Spee B, Kruitwagen HS, Chen C, Geijsen N, Oosterhoff LA, van Wolferen ME, Pelaez N, Fieten H, Wubbolts RW, Grinwis GC, Chan J, Huch M, Vries RRG, Clevers H, de Bruin A, Rothuizen J, Penning LC, Schotanus BA.

Stem Cell Reports. 2015 Nov 10;5(5):895-907. doi: 10.1016/j.stemcr.2015.09.002. Epub 2015 Oct 8.

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