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Items: 17


The antimicrobial peptide SAAP-148 combats drug-resistant bacteria and biofilms.

de Breij A, Riool M, Cordfunke RA, Malanovic N, de Boer L, Koning RI, Ravensbergen E, Franken M, van der Heijde T, Boekema BK, Kwakman PHS, Kamp N, El Ghalbzouri A, Lohner K, Zaat SAJ, Drijfhout JW, Nibbering PH.

Sci Transl Med. 2018 Jan 10;10(423). pii: eaan4044. doi: 10.1126/scitranslmed.aan4044. Erratum in: Sci Transl Med. 2018 Mar 21;10 (433):.


Antimicrobial Peptides in Biomedical Device Manufacturing.

Riool M, de Breij A, Drijfhout JW, Nibbering PH, Zaat SAJ.

Front Chem. 2017 Aug 24;5:63. doi: 10.3389/fchem.2017.00063. eCollection 2017. Review.


Phylogenetic signal in phenotypic traits related to carbon source assimilation and chemical sensitivity in Acinetobacter species.

Van Assche A, Álvarez-Pérez S, de Breij A, De Brabanter J, Willems KA, Dijkshoorn L, Lievens B.

Appl Microbiol Biotechnol. 2017 Jan;101(1):367-379. doi: 10.1007/s00253-016-7866-0. Epub 2016 Oct 12.


The licorice pentacyclic triterpenoid component 18β-glycyrrhetinic acid enhances the activity of antibiotics against strains of methicillin-resistant Staphylococcus aureus.

de Breij A, Karnaoukh TG, Schrumpf J, Hiemstra PS, Nibbering PH, van Dissel JT, de Visser PC.

Eur J Clin Microbiol Infect Dis. 2016 Apr;35(4):555-62. doi: 10.1007/s10096-015-2570-z. Epub 2016 Jan 15.


Prevention of Staphylococcus aureus biomaterial-associated infections using a polymer-lipid coating containing the antimicrobial peptide OP-145.

de Breij A, Riool M, Kwakman PH, de Boer L, Cordfunke RA, Drijfhout JW, Cohen O, Emanuel N, Zaat SA, Nibbering PH, Moriarty TF.

J Control Release. 2016 Jan 28;222:1-8. doi: 10.1016/j.jconrel.2015.12.003. Epub 2015 Dec 3.


Phospholipid-driven differences determine the action of the synthetic antimicrobial peptide OP-145 on Gram-positive bacterial and mammalian membrane model systems.

Malanovic N, Leber R, Schmuck M, Kriechbaum M, Cordfunke RA, Drijfhout JW, de Breij A, Nibbering PH, Kolb D, Lohner K.

Biochim Biophys Acta. 2015 Oct;1848(10 Pt A):2437-47. doi: 10.1016/j.bbamem.2015.07.010. Epub 2015 Jul 23.


A doxycycline-loaded polymer-lipid encapsulation matrix coating for the prevention of implant-related osteomyelitis due to doxycycline-resistant methicillin-resistant Staphylococcus aureus.

Metsemakers WJ, Emanuel N, Cohen O, Reichart M, Potapova I, Schmid T, Segal D, Riool M, Kwakman PH, de Boer L, de Breij A, Nibbering PH, Richards RG, Zaat SA, Moriarty TF.

J Control Release. 2015 Jul 10;209:47-56. doi: 10.1016/j.jconrel.2015.04.022. Epub 2015 Apr 21.


LL-37-derived peptides eradicate multidrug-resistant Staphylococcus aureus from thermally wounded human skin equivalents.

Haisma EM, de Breij A, Chan H, van Dissel JT, Drijfhout JW, Hiemstra PS, El Ghalbzouri A, Nibbering PH.

Antimicrob Agents Chemother. 2014 Aug;58(8):4411-9. doi: 10.1128/AAC.02554-14. Epub 2014 May 19.


Inflammatory and antimicrobial responses to methicillin-resistant Staphylococcus aureus in an in vitro wound infection model.

Haisma EM, Rietveld MH, de Breij A, van Dissel JT, El Ghalbzouri A, Nibbering PH.

PLoS One. 2013 Dec 10;8(12):e82800. doi: 10.1371/journal.pone.0082800. eCollection 2013.


MAVIS: an integrated system for live microscopy and vitrification.

Koning RI, Faas FG, Boonekamp M, de Visser B, Janse J, Wiegant JC, de Breij A, Willemse J, Nibbering PH, Tanke HJ, Koster AJ.

Ultramicroscopy. 2014 Aug;143:67-76. doi: 10.1016/j.ultramic.2013.10.007. Epub 2013 Oct 18.


Cryo-electron tomography analysis of membrane vesicles from Acinetobacter baumannii ATCC19606 T.

Koning RI, de Breij A, Oostergetel GT, Nibbering PH, Koster AJ, Dijkshoorn L.

Res Microbiol. 2013 Jun;164(5):397-405. doi: 10.1016/j.resmic.2013.02.007. Epub 2013 Mar 19.


The success of acinetobacter species; genetic, metabolic and virulence attributes.

Peleg AY, de Breij A, Adams MD, Cerqueira GM, Mocali S, Galardini M, Nibbering PH, Earl AM, Ward DV, Paterson DL, Seifert H, Dijkshoorn L.

PLoS One. 2012;7(10):e46984. doi: 10.1371/journal.pone.0046984. Epub 2012 Oct 29.


Differences in Acinetobacter baumannii strains and host innate immune response determine morbidity and mortality in experimental pneumonia.

de Breij A, Eveillard M, Dijkshoorn L, van den Broek PJ, Nibbering PH, Joly-Guillou ML.

PLoS One. 2012;7(2):e30673. doi: 10.1371/journal.pone.0030673. Epub 2012 Feb 8.


Three-dimensional human skin equivalent as a tool to study Acinetobacter baumannii colonization.

de Breij A, Haisma EM, Rietveld M, El Ghalbzouri A, van den Broek PJ, Dijkshoorn L, Nibbering PH.

Antimicrob Agents Chemother. 2012 May;56(5):2459-64. doi: 10.1128/AAC.05975-11. Epub 2012 Jan 30.


Do biofilm formation and interactions with human cells explain the clinical success of Acinetobacter baumannii?

de Breij A, Dijkshoorn L, Lagendijk E, van der Meer J, Koster A, Bloemberg G, Wolterbeek R, van den Broek P, Nibbering P.

PLoS One. 2010 May 20;5(5):e10732. doi: 10.1371/journal.pone.0010732.


CsuA/BABCDE-dependent pili are not involved in the adherence of Acinetobacter baumannii ATCC19606(T) to human airway epithelial cells and their inflammatory response.

de Breij A, Gaddy J, van der Meer J, Koning R, Koster A, van den Broek P, Actis L, Nibbering P, Dijkshoorn L.

Res Microbiol. 2009 Apr;160(3):213-8. doi: 10.1016/j.resmic.2009.01.002.


Lower expression of TLR2 and SOCS-3 is associated with Schistosoma haematobium infection and with lower risk for allergic reactivity in children living in a rural area in Ghana.

Hartgers FC, Obeng BB, Kruize YC, Duijvestein M, de Breij A, Amoah A, Larbi IA, van Ree R, Wilson MD, Rodrigues LC, Boakye DA, Yazdanbakhsh M.

PLoS Negl Trop Dis. 2008 Apr 16;2(4):e227. doi: 10.1371/journal.pntd.0000227.

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