Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 41

1.

Activation of the Nrf2 response by intrinsic hepatotoxic drugs correlates with suppression of NF-κB activation and sensitizes toward TNFα-induced cytotoxicity.

Herpers B, Wink S, Fredriksson L, Di Z, Hendriks G, Vrieling H, de Bont H, van de Water B.

Arch Toxicol. 2016 May;90(5):1163-79. doi: 10.1007/s00204-015-1536-3. Epub 2015 May 31.

2.

SYK is a candidate kinase target for the treatment of advanced prostate cancer.

Ghotra VP, He S, van der Horst G, Nijhoff S, de Bont H, Lekkerkerker A, Janssen R, Jenster G, van Leenders GJ, Hoogland AM, Verhoef EI, Baranski Z, Xiong J, van de Water B, van der Pluijm G, Snaar-Jagalska BE, Danen EH.

Cancer Res. 2015 Jan 1;75(1):230-40. doi: 10.1158/0008-5472.CAN-14-0629. Epub 2014 Nov 11.

3.

Drug-induced endoplasmic reticulum and oxidative stress responses independently sensitize toward TNFα-mediated hepatotoxicity.

Fredriksson L, Wink S, Herpers B, Benedetti G, Hadi M, de Bont H, Groothuis G, Luijten M, Danen E, de Graauw M, Meerman J, van de Water B.

Toxicol Sci. 2014 Jul;140(1):144-59. doi: 10.1093/toxsci/kfu072. Epub 2014 Apr 20.

PMID:
24752500
4.

The residence time of focal adhesion kinase (FAK) and paxillin at focal adhesions in renal epithelial cells is determined by adhesion size, strength and life cycle status.

Le Dévédec SE, Geverts B, de Bont H, Yan K, Verbeek FJ, Houtsmuller AB, van de Water B.

J Cell Sci. 2012 Oct 1;125(Pt 19):4498-506. doi: 10.1242/jcs.104273. Epub 2012 Jul 5.

5.

Automated whole animal bio-imaging assay for human cancer dissemination.

Ghotra VP, He S, de Bont H, van der Ent W, Spaink HP, van de Water B, Snaar-Jagalska BE, Danen EH.

PLoS One. 2012;7(2):e31281. doi: 10.1371/journal.pone.0031281. Epub 2012 Feb 8.

6.

Functional screening with a live cell imaging-based random cell migration assay.

van Roosmalen W, Le Dévédec SE, Zovko S, de Bont H, van de Water B.

Methods Mol Biol. 2011;769:435-48. doi: 10.1007/978-1-61779-207-6_29.

PMID:
21748693
7.

Two-photon intravital multicolour imaging to study metastatic behaviour of cancer cells in vivo.

Le Dévédec SE, van Roosmalen W, Pont C, Lalai R, de Bont H, van de Water B.

Methods Mol Biol. 2011;769:331-49. doi: 10.1007/978-1-61779-207-6_22.

PMID:
21748686
8.

Elevated insulin-like growth factor 1 receptor signaling induces antiestrogen resistance through the MAPK/ERK and PI3K/Akt signaling routes.

Zhang Y, Moerkens M, Ramaiahgari S, de Bont H, Price L, Meerman J, van de Water B.

Breast Cancer Res. 2011 May 19;13(3):R52. doi: 10.1186/bcr2883.

9.

Diclofenac inhibits tumor necrosis factor-α-induced nuclear factor-κB activation causing synergistic hepatocyte apoptosis.

Fredriksson L, Herpers B, Benedetti G, Matadin Q, Puigvert JC, de Bont H, Dragovic S, Vermeulen NP, Commandeur JN, Danen E, de Graauw M, van de Water B.

Hepatology. 2011 Jun;53(6):2027-41. doi: 10.1002/hep.24314.

PMID:
21433042
10.

Systems microscopy approaches to understand cancer cell migration and metastasis.

Le Dévédec SE, Yan K, de Bont H, Ghotra V, Truong H, Danen EH, Verbeek F, van de Water B.

Cell Mol Life Sci. 2010 Oct;67(19):3219-40. doi: 10.1007/s00018-010-0419-2. Epub 2010 Jun 18. Review.

11.

High-throughput live cell imaging of apoptosis.

Puigvert JC, de Bont H, van de Water B, Danen EH.

Curr Protoc Cell Biol. 2010 Jun;Chapter 18:Unit 18.10.1-13. doi: 10.1002/0471143030.cb1810s47.

PMID:
20521231
12.

Two-photon intravital multicolor imaging combined with inducible gene expression to distinguish metastatic behavior of breast cancer cells in vivo.

Le Dévédec SE, Lalai R, Pont C, de Bont H, van de Water B.

Mol Imaging Biol. 2011 Feb;13(1):67-77. doi: 10.1007/s11307-010-0307-z.

13.

Complete focal adhesion kinase deficiency in the mammary gland causes ductal dilation and aberrant branching morphogenesis through defects in Rho kinase-dependent cell contractility.

van Miltenburg MH, Lalai R, de Bont H, van Waaij E, Beggs H, Danen EH, van de Water B.

FASEB J. 2009 Oct;23(10):3482-93. doi: 10.1096/fj.08-123398. Epub 2009 Jul 7.

PMID:
19584305
14.

Disrupted expression of CXCL5 in colorectal cancer is associated with rapid tumor formation in rats and poor prognosis in patients.

Speetjens FM, Kuppen PJ, Sandel MH, Menon AG, Burg D, van de Velde CJ, Tollenaar RA, de Bont HJ, Nagelkerke JF.

Clin Cancer Res. 2008 Apr 15;14(8):2276-84. doi: 10.1158/1078-0432.CCR-07-4045.

15.

Caspase-3 activity predicts local recurrence in rectal cancer.

de Heer P, de Bruin EC, Klein-Kranenbarg E, Aalbers RI, Marijnen CA, Putter H, de Bont HJ, Nagelkerke JF, van Krieken JH, Verspaget HW, van de Velde CJ, Kuppen PJ; Dutch Colorectal Cancer Group.

Clin Cancer Res. 2007 Oct 1;13(19):5810-5.

16.

Impaired activation of caspases and prevention of mitochondrial dysfunction in the metastatic colon carcinoma CC531s-m2 cell line.

Velthuis JH, Gavric Z, de Bont HJ, Nagelkerke JF.

Biochem Pharmacol. 2005 Feb 1;69(3):463-71. Epub 2004 Dec 15.

PMID:
15652237
17.

Rat colon carcinoma cells that survived systemic immune surveillance are less sensitive to NK-cell mediated apoptosis.

Velthuis JH, Stitzinger M, Aalbers RI, de Bont HJ, Mulder GJ, Kuppen PJ, Nagelkerke JF.

Clin Exp Metastasis. 2003;20(8):713-21.

PMID:
14713105
18.

Interleukin-2 activated NK cells do not use the CD95L- and TRAIL-pathways in the rapid induction of apoptosis of rat colon carcinoma CC531s cells.

Velthuis JH, de Bont HJ, Medema JP, Kuppen PJ, Mulder GJ, Nagelkerke JF.

Immunobiology. 2003;207(2):115-27.

PMID:
12675269
20.

The role of calpains in apoptotic changes in isolated hepatocytes after attack by Natural Killer cells.

Blom WM, de Bont HJ, Mulder GJ, Nagelkerke JF.

Environ Toxicol Pharmacol. 2002 Jul;11(3-4):159-65.

PMID:
21782598
21.

Distinct intracellular signaling in tumor necrosis factor-related apoptosis-inducing ligand- and CD95 ligand-mediated apoptosis.

Velthuis JH, Rouschop KM, De Bont HJ, Mulder GJ, Nagelkerke JF.

J Biol Chem. 2002 Jul 5;277(27):24631-7. Epub 2002 Apr 29.

22.

Remodeling of the actin cytoskeleton of target hepatocytes and NK cells during induction of apoptosis.

Blom WM, de Bont HJ, Meijerman I, Kuppen PJ, van Der Meulen H, Mulder GJ, Nagelkerke JF.

Cell Motil Cytoskeleton. 2001 Jun;49(2):78-92.

PMID:
11443738
23.

Prevention of cycloheximide-induced apoptosis in hepatocytes by adenosine and by caspase inhibitors.

Blom WM, de Bont HJ, Meijerman I, Mulder GJ, Nagelkerke JF.

Biochem Pharmacol. 1999 Dec 15;58(12):1891-8.

PMID:
10591143
25.
26.

Interleukin-2-activated natural killer cells can induce both apoptosis and necrosis in rat hepatocytes.

Blom WM, De Bont HJ, Meijerman I, Kuppen PJ, Mulder GJ, Nagelkerke JF.

Hepatology. 1999 Mar;29(3):785-92.

PMID:
10051480
27.

Nuclear accumulation of G-actin in isolated rat hepatocytes by adenine nucleotides.

Meijerman I, Blom WM, de Bont HJ, Mulder GJ, Nagelkerke JF.

Biochem Biophys Res Commun. 1997 Nov 26;240(3):697-700.

PMID:
9398629
28.

Use of video microscopy to study the mechanisms of cytotoxicity in vitro in individual living cells.

Nagelkerke JF, de Bont HJ.

Toxicol In Vitro. 1997 Oct;11(5):531-4.

PMID:
20654347
29.

The role of a purinergic P2z receptor in calcium-dependent cell killing of isolated rat hepatocytes by extracellular adenosine triphosphate.

Zoetewij JP, van de Water B, de Bont HJ, Nagelkerke JF.

Hepatology. 1996 Apr;23(4):858-65.

PMID:
8666342
30.

Inhibition of succinate:ubiquinone reductase and decrease of ubiquinol in nephrotoxic cysteine S-conjugate-induced oxidative cell injury.

van de Water B, Zoeteweij JP, de Bont HJ, Nagelkerke JF.

Mol Pharmacol. 1995 Nov;48(5):928-37.

PMID:
7476924
33.

Verification of the position of the phosphate group in some synthetic phosphopeptides by fast-atom bombardment and tandem mass spectrometry.

Nijenhuis AA, Fokkens RH, Nibbering NM, van Oijen AH, de Bont HB, Liskamp RM, van Boom JH.

Rapid Commun Mass Spectrom. 1993 Aug;7(8):774-9.

PMID:
8374165
34.
35.

Binding of the radioligand [35S]adenosine 5'-O-(2-thiodiphosphate) and intracellular calcium response in rat liver parenchymal cells.

van Rhee AM, van Winden EC, Nagelkerke JF, de Bont HJ, IJzerman AP, Soudijn W.

Biochem Pharmacol. 1993 Feb 24;45(4):801-7.

PMID:
8452554
36.

Calcium-induced cytotoxicity in hepatocytes after exposure to extracellular ATP is dependent on inorganic phosphate. Effects on mitochondrial calcium.

Zoeteweij JP, van de Water B, de Bont HJ, Mulder GJ, Nagelkerke JF.

J Biol Chem. 1993 Feb 15;268(5):3384-8.

37.

Fasting increases the susceptibility of rat hepatocytes to the cytotoxic effects of N-hydroxy-acetylaminofluorene. Effects on mitochondrial respiration and membrane potential.

Nagelkerke JF, de Bont A, de Bont HJ, Tijdens IB, Mulder GJ, Meerman JH.

Biochem Pharmacol. 1992 Dec 15;44(12):2339-45.

PMID:
1472098
38.
39.

Role of microtubuli in secretion of very-low-density lipoprotein in isolated rat hepatocytes: early effects of thiol reagents.

Nagelkerke JF, van de Water B, Twiss IM, Zoetewey JP, de Bont HJ, Dogterom P, Mulder GJ.

Hepatology. 1991 Dec;14(6):1259-68.

PMID:
1959877
41.

Synthesis of a substrate of protein kinase C and its corresponding phosphopeptide.

de Bont HB, Liskamp RM, O'Brian CA, Erkelens C, Veeneman GH, van Boom JH.

Int J Pept Protein Res. 1989 Feb;33(2):115-23.

PMID:
2707968

Supplemental Content

Loading ...
Support Center