Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 188

1.

An integrative omics approach to unravel toxicity mechanisms of environmental chemicals: effects of a formulated herbicide.

Simões T, Novais SC, Natal-da-Luz T, Devreese B, de Boer T, Roelofs D, Sousa JP, van Straalen NM, Lemos MFL.

Sci Rep. 2018 Jul 27;8(1):11376. doi: 10.1038/s41598-018-29662-6.

2.

Cardiac Ca2+ signalling in zebrafish: Translation of findings to man.

van Opbergen CJM, van der Voorn SM, Vos MA, de Boer TP, van Veen TAB.

Prog Biophys Mol Biol. 2018 May 7. pii: S0079-6107(18)30031-2. doi: 10.1016/j.pbiomolbio.2018.05.002. [Epub ahead of print] Review.

PMID:
29746887
3.

Population-specific transcriptional differences associated with freeze tolerance in a terrestrial worm.

de Boer TE, Roelofs D, Vooijs R, Holmstrup M, Amorim MJB.

Ecol Evol. 2018 Mar 11;8(7):3774-3786. doi: 10.1002/ece3.3602. eCollection 2018 Apr.

4.

Sinusoidal voltage protocols for rapid characterisation of ion channel kinetics.

Beattie KA, Hill AP, Bardenet R, Cui Y, Vandenberg JI, Gavaghan DJ, de Boer TP, Mirams GR.

J Physiol. 2018 May 15;596(10):1813-1828. doi: 10.1113/JP275733. Epub 2018 Apr 17.

5.

A Hybrid Model for Safety Pharmacology on an Automated Patch Clamp Platform: Using Dynamic Clamp to Join iPSC-Derived Cardiomyocytes and Simulations of Ik1 Ion Channels in Real-Time.

Goversen B, Becker N, Stoelzle-Feix S, Obergrussberger A, Vos MA, van Veen TAB, Fertig N, de Boer TP.

Front Physiol. 2018 Jan 19;8:1094. doi: 10.3389/fphys.2017.01094. eCollection 2017.

6.

Action potential contour and inter-species differences.

de Boer TP, Stengl M.

Europace. 2017 Oct 31. doi: 10.1093/europace/eux308. [Epub ahead of print] No abstract available.

PMID:
29096032
7.

BiobankUniverse: automatic matchmaking between datasets for biobank data discovery and integration.

Pang C, Kelpin F, van Enckevort D, Eklund N, Silander K, Hendriksen D, de Haan M, Jetten J, de Boer T, Charbon B, Holub P, Hillege H, Swertz MA.

Bioinformatics. 2017 Nov 15;33(22):3627-3634. doi: 10.1093/bioinformatics/btx478.

8.

The immature electrophysiological phenotype of iPSC-CMs still hampers in vitro drug screening: Special focus on IK1.

Goversen B, van der Heyden MAG, van Veen TAB, de Boer TP.

Pharmacol Ther. 2018 Mar;183:127-136. doi: 10.1016/j.pharmthera.2017.10.001. Epub 2017 Oct 3. Review.

9.

Peptide microarray profiling identifies phospholipase C gamma 1 (PLC-γ1) as a potential target for t(8;21) AML.

Mahmud H, Scherpen FJG, de Boer TM, Lourens HJ, Schoenherr C, Eder M, Scherr M, Guryev V, De Bont ES.

Oncotarget. 2017 Jun 27;8(40):67344-67354. doi: 10.18632/oncotarget.18631. eCollection 2017 Sep 15.

10.

Candidate genes for shell colour polymorphism in Cepaea nemoralis.

Kerkvliet J, de Boer T, Schilthuizen M, Kraaijeveld K.

PeerJ. 2017 Sep 18;5:e3715. doi: 10.7717/peerj.3715. eCollection 2017.

11.

Acetyl-4'-phosphopantetheine is stable in serum and prevents phenotypes induced by pantothenate kinase deficiency.

Di Meo I, Colombelli C, Srinivasan B, de Villiers M, Hamada J, Jeong SY, Fox R, Woltjer RL, Tepper PG, Lahaye LL, Rizzetto E, Harrs CH, de Boer T, van der Zwaag M, Jenko B, Čusak A, Pahor J, Kosec G, Grzeschik NA, Hayflick SJ, Tiranti V, Sibon OCM.

Sci Rep. 2017 Sep 12;7(1):11260. doi: 10.1038/s41598-017-11564-8.

12.

Cardiac optogenetics: using light to monitor cardiac physiology.

Koopman CD, Zimmermann WH, Knöpfel T, de Boer TP.

Basic Res Cardiol. 2017 Aug 31;112(5):56. doi: 10.1007/s00395-017-0645-y. Review.

13.

eSolv, a CellML-based simulation front-end for online teaching.

de Boer TP, van der Werf S, Hennekam B, Nickerson DP, Garny A, Gerbrands M, Bouwmeester RAM, Rozendal AP, Torfs E, van Rijen HVM.

Adv Physiol Educ. 2017 Sep 1;41(3):425-427. doi: 10.1152/advan.00127.2016. No abstract available.

14.

The concept of triple wavefront fusion during biventricular pacing: Using the EGM to produce the best acute hemodynamic improvement in CRT.

Ter Horst IAH, Bogaard MD, Tuinenburg AE, Mast TP, de Boer TP, Doevendans PAFM, Meine M.

Pacing Clin Electrophysiol. 2017 Jul;40(7):873-882. doi: 10.1111/pace.13118. Epub 2017 Jun 16.

PMID:
28543106
15.

Draft Genome Sequence of Bacillus toyonensis VU-DES13, Isolated from Folsomia candida (Collembola: Entomobryidae).

Janssens TKS, de Boer TE, Agamennone V, Zaagman N, van Straalen NM, Roelofs D.

Genome Announc. 2017 May 11;5(19). pii: e00287-17. doi: 10.1128/genomeA.00287-17.

16.

Commentary: Reciprocal Modulation of IK1-INa Extends Excitability in Cardiac Ventricular Cells.

Goversen B, de Boer TP, van der Heyden MA.

Front Physiol. 2016 Dec 23;7:647. doi: 10.3389/fphys.2016.00647. eCollection 2016. No abstract available.

17.

Mechanisms of phenanthrene toxicity in the soil invertebrate, Enchytraeus crypticus.

Roelofs D, Bicho RC, de Boer TE, Castro-Ferreira MP, Montagne-Wajer K, van Gestel CA, Soares AM, van Straalen NM, Amorim MJ.

Environ Toxicol Chem. 2016 Nov;35(11):2713-2720. doi: 10.1002/etc.3433.

PMID:
27017953
18.

Quantifying Beta-Galactosylceramide Kinetics in Cerebrospinal Fluid of Healthy Subjects Using Deuterium Labeling.

Kanhai K, Goulooze SC, Stevens J, Hay JL, Dent G, Verma A, Hankemeier T, de Boer T, Meijering H, Chavez JC, Cohen AF, Groeneveld GJ.

Clin Transl Sci. 2016 Dec;9(6):321-327. doi: 10.1111/cts.12424. Epub 2016 Oct 15.

19.

GNB5 Mutations Cause an Autosomal-Recessive Multisystem Syndrome with Sinus Bradycardia and Cognitive Disability.

Lodder EM, De Nittis P, Koopman CD, Wiszniewski W, Moura de Souza CF, Lahrouchi N, Guex N, Napolioni V, Tessadori F, Beekman L, Nannenberg EA, Boualla L, Blom NA, de Graaff W, Kamermans M, Cocciadiferro D, Malerba N, Mandriani B, Coban Akdemir ZH, Fish RJ, Eldomery MK, Ratbi I, Wilde AAM, de Boer T, Simonds WF, Neerman-Arbez M, Sutton VR, Kok F, Lupski JR, Reymond A, Bezzina CR, Bakkers J, Merla G.

Am J Hum Genet. 2016 Sep 1;99(3):786. doi: 10.1016/j.ajhg.2016.08.011. Epub 2016 Sep 1. No abstract available.

20.

GNB5 Mutations Cause an Autosomal-Recessive Multisystem Syndrome with Sinus Bradycardia and Cognitive Disability.

Lodder EM, De Nittis P, Koopman CD, Wiszniewski W, Moura de Souza CF, Lahrouchi N, Guex N, Napolioni V, Tessadori F, Beekman L, Nannenberg EA, Boualla L, Blom NA, de Graaff W, Kamermans M, Cocciadiferro D, Malerba N, Mandriani B, Akdemir ZHC, Fish RJ, Eldomery MK, Ratbi I, Wilde AAM, de Boer T, Simonds WF, Neerman-Arbez M, Sutton VR, Kok F, Lupski JR, Reymond A, Bezzina CR, Bakkers J, Merla G.

Am J Hum Genet. 2016 Sep 1;99(3):704-710. doi: 10.1016/j.ajhg.2016.06.025. Epub 2016 Aug 11. Erratum in: Am J Hum Genet. 2016 Sep 1;99(3):786.

21.

MOLGENIS/connect: a system for semi-automatic integration of heterogeneous phenotype data with applications in biobanks.

Pang C, van Enckevort D, de Haan M, Kelpin F, Jetten J, Hendriksen D, de Boer T, Charbon B, Winder E, van der Velde KJ, Doiron D, Fortier I, Hillege H, Swertz MA.

Bioinformatics. 2016 Jul 15;32(14):2176-83. doi: 10.1093/bioinformatics/btw155. Epub 2016 Mar 21.

22.

Identifying 24 h variation in the pharmacokinetics of levofloxacin: a population pharmacokinetic approach.

Kervezee L, Stevens J, Birkhoff W, Kamerling IM, de Boer T, Dröge M, Meijer JH, Burggraaf J.

Br J Clin Pharmacol. 2016 Feb;81(2):256-68. doi: 10.1111/bcp.12783. Epub 2015 Nov 25.

23.

Perpetuation of torsade de pointes in heterogeneous hearts: competing foci or re-entry?

Vandersickel N, de Boer TP, Vos MA, Panfilov AV.

J Physiol. 2016 Dec 1;594(23):6865-6878. doi: 10.1113/JP271728. Epub 2016 Mar 4.

24.

Uncertainty and variability in models of the cardiac action potential: Can we build trustworthy models?

Johnstone RH, Chang ETY, Bardenet R, de Boer TP, Gavaghan DJ, Pathmanathan P, Clayton RH, Mirams GR.

J Mol Cell Cardiol. 2016 Jul;96:49-62. doi: 10.1016/j.yjmcc.2015.11.018. Epub 2015 Dec 2.

25.

A 2015 focus on preventing drug-induced arrhythmias.

Bossu A, van der Heyden MA, de Boer TP, Vos MA.

Expert Rev Cardiovasc Ther. 2016;14(2):245-53. doi: 10.1586/14779072.2016.1116940. Epub 2015 Nov 26. Review.

PMID:
26560188
26.

Combined Transcriptomics Analysis for Classification of Adverse Effects As a Potential End Point in Effect Based Screening.

de Boer TE, Janssens TK, Legler J, van Straalen NM, Roelofs D.

Environ Sci Technol. 2015 Dec 15;49(24):14274-81. doi: 10.1021/acs.est.5b03443. Epub 2015 Nov 13.

PMID:
26523736
27.

SORTA: a system for ontology-based re-coding and technical annotation of biomedical phenotype data.

Pang C, Sollie A, Sijtsma A, Hendriksen D, Charbon B, de Haan M, de Boer T, Kelpin F, Jetten J, van der Velde JK, Smidt N, Sijmons R, Hillege H, Swertz MA.

Database (Oxford). 2015 Sep 18;2015. pii: bav089. doi: 10.1093/database/bav089. Print 2015.

28.

Arrhythmogenic Remodeling in Murine Models of Deoxycorticosterone Acetate-Salt-Induced and 5/6-Subtotal Nephrectomy-Salt-Induced Cardiorenal Disease.

Fontes MS, Papazova DA, van Koppen A, de Jong S, Korte SM, Bongartz LG, Nguyen TQ, Bierhuizen MF, de Boer TP, van Veen TA, Verhaar MC, Joles JA, van Rijen HV.

Cardiorenal Med. 2015 Jun;5(3):208-18. doi: 10.1159/000430475. Epub 2015 Jun 5.

29.

Sensing Cardiac Electrical Activity With a Cardiac Myocyte--Targeted Optogenetic Voltage Indicator.

Chang Liao ML, de Boer TP, Mutoh H, Raad N, Richter C, Wagner E, Downie BR, Unsöld B, Arooj I, Streckfuss-Bömeke K, Döker S, Luther S, Guan K, Wagner S, Lehnart SE, Maier LS, Stühmer W, Wettwer E, van Veen T, Morlock MM, Knöpfel T, Zimmermann WH.

Circ Res. 2015 Aug 14;117(5):401-12. doi: 10.1161/CIRCRESAHA.117.306143. Epub 2015 Jun 15.

PMID:
26078285
30.

Repeat analysis and incurred sample reanalysis: recommendation for best practices and harmonization from the global bioanalysis consortium harmonization team.

Fluhler E, Vazvaei F, Singhal P, Vinck P, Li W, Bhatt J, de Boer T, Chaudhary A, Tangiuchi M, Rezende V, Zhong D.

AAPS J. 2014 Nov;16(6):1167-74. doi: 10.1208/s12248-014-9644-1. Epub 2014 Aug 19. Review.

31.

Transcriptome assembly and microarray construction for Enchytraeus crypticus, a model oligochaete to assess stress response mechanisms derived from soil conditions.

Castro-Ferreira MP, de Boer TE, Colbourne JK, Vooijs R, van Gestel CA, van Straalen NM, Soares AM, Amorim MJ, Roelofs D.

BMC Genomics. 2014 Apr 23;15:302. doi: 10.1186/1471-2164-15-302.

32.

Changes in Cx43 and NaV1.5 expression precede the occurrence of substantial fibrosis in calcineurin-induced murine cardiac hypertrophy.

Fontes MS, Raaijmakers AJ, van Doorn T, Kok B, Nieuwenhuis S, van der Nagel R, Vos MA, de Boer TP, van Rijen HV, Bierhuizen MF.

PLoS One. 2014 Jan 31;9(1):e87226. doi: 10.1371/journal.pone.0087226. eCollection 2014.

33.

Peculiar observations in measuring testosterone in women treated with oral contraceptives supplemented with dehydroepiandrosterone (DHEA).

Heijboer AC, Zimmerman Y, de Boer T, Coelingh Bennink H, Blankenstein MA.

Clin Chim Acta. 2014 Mar 20;430:92-5. doi: 10.1016/j.cca.2013.12.042. Epub 2014 Jan 7.

PMID:
24406275
34.

Integrating transcriptomics into triad-based soil-quality assessment.

Chen G, de Boer TE, Wagelmans M, van Gestel CA, van Straalen NM, Roelofs D.

Environ Toxicol Chem. 2014 Apr;33(4):900-9. doi: 10.1002/etc.2508. Epub 2014 Feb 26.

PMID:
24382659
35.

Measurement of coherence decay in GaMnAs using femtosecond four-wave mixing.

Webber D, de Boer T, Yildirim M, March S, Mathew R, Gamouras A, Liu X, Dobrowolska M, Furdyna J, Hall K.

J Vis Exp. 2013 Dec 3;(82):51094. doi: 10.3791/51094.

36.

Palmitoylethanolamide: A Natural Body-Own Anti-Inflammatory Agent, Effective and Safe against Influenza and Common Cold.

Keppel Hesselink JM, de Boer T, Witkamp RF.

Int J Inflam. 2013;2013:151028. doi: 10.1155/2013/151028. Epub 2013 Aug 27. Review.

37.

The relation between gaze behavior and categorization: does where we look determine what we see?

Hartendorp MO, Van der Stigchel S, Hooge I, Mostert J, de Boer T, Postma A.

J Vis. 2013 May 14;13(6). pii: 6. doi: 10.1167/13.6.6.

PMID:
23674580
38.

Efficient and specific cardiac IK₁ inhibition by a new pentamidine analogue.

Takanari H, Nalos L, Stary-Weinzinger A, de Git KC, Varkevisser R, Linder T, Houtman MJ, Peschar M, de Boer TP, Tidwell RR, Rook MB, Vos MA, van der Heyden MA.

Cardiovasc Res. 2013 Jul 1;99(1):203-14. doi: 10.1093/cvr/cvt103. Epub 2013 Apr 25.

PMID:
23625347
39.

Platelet-rich plasma can replace fetal bovine serum in human meniscus cell cultures.

Gonzales VK, de Mulder EL, de Boer T, Hannink G, van Tienen TG, van Heerde WL, Buma P.

Tissue Eng Part C Methods. 2013 Nov;19(11):892-9. doi: 10.1089/ten.tec.2013.0009. Epub 2013 Apr 27.

PMID:
23621108
40.

Cardiac ion channel trafficking defects and drugs.

de Git KC, de Boer TP, Vos MA, van der Heyden MA.

Pharmacol Ther. 2013 Jul;139(1):24-31. doi: 10.1016/j.pharmthera.2013.03.008. Epub 2013 Apr 2. Review.

PMID:
23558293
41.

A functional isopenicillin N synthase in an animal genome.

Roelofs D, Timmermans MJ, Hensbergen P, van Leeuwen H, Koopman J, Faddeeva A, Suring W, de Boer TE, Mariën J, Boer R, Bovenberg R, van Straalen NM.

Mol Biol Evol. 2013 Mar;30(3):541-8. doi: 10.1093/molbev/mss269. Epub 2012 Nov 29.

PMID:
23204388
42.

Recommendations on biomarker bioanalytical method validation by GCC.

Hougton R, Gouty D, Allinson J, Green R, Losauro M, Lowes S, LeLacheur R, Garofolo F, Couerbe P, Bronner S, Struwe P, Schiebl C, Sangster T, Pattison C, Islam R, Garofolo W, Pawula M, Buonarati M, Hayes R, Cameron M, Nicholson R, Harman J, Wieling J, De Boer T, Reuschel S, Cojocaru L, Harter T, Malone M, Nowatzke W.

Bioanalysis. 2012 Oct;4(20):2439-46. doi: 10.4155/bio.12.197.

43.

Serial CSF sampling over a period of 30 h via an indwelling spinal catheter in healthy volunteers: headache, back pain, tolerability and measured acetylcholine profile.

den Daas I, Wemer J, Abou Farha K, Tamminga W, de Boer T, Spanjersberg R, Struys MM, Absalom AR.

Eur J Clin Pharmacol. 2013 May;69(5):1083-90. doi: 10.1007/s00228-012-1443-y. Epub 2012 Nov 10.

PMID:
23143156
44.

Recommendations on bioanalytical method stability implications of co-administered and co-formulated drugs by Global CRO Council for Bioanalysis (GCC).

Lowes S, Boterman M, Doig M, Breda M, Jersey J, Lelacheur R, Shoup R, Garofolo F, Dumont I, Martinez S, Needham S, Zimmer J, Caturla MC, Couerbe P, Maltas J, Steffen R, Petrilla J, Safavi A, Awaiye K, Bhatti M, Sheldon C, Schiebl C, Struwe P, Turk D, Sangster T, Pattison C, Fast D, Goodwin L, Kamerud J, Dinan A, Mamelak D, Islam R, Segers R, Lin ZJ, Hillier J, Garofolo W, Folguera L, Zimmer D, Zimmermann T, Pawula M, Moussallie M, de Souza Teixeira L, Rocha T, Allinson J, Jardieu P, Tang D, Gouty D, Wright L, Truog J, Lin J, Yamashita Y, Khan M, Liu Y, Xu A, Lundberg R, Cox C, Breau A, Hayes R, Bigogno C, Schoutsen D, Dilger C, Jonker J, Bouhajib M, Levesque A, Gagnon-Carignan S, Harman J, Nicholson R, Jenkins R, Warren M, Lin MH, Karnik S, De Boer T, Houghton R, Green R, Demaio W, Sable R, Smith K, Siethoff C, Cojocaru L, Allen M, Reuschel S, Gonzalez P, Harter T, Fatmi S, Rock M, Vija J, Sayyarpour F, Malone M, Nowatzke W, Best S, Fang X.

Bioanalysis. 2012 Sep;4(17):2117-26.

45.

Recommendations on ISR in multi analyte assays, QA/bioanalytical consultants and GCP by Global CRO Council for Bioanalysis (GCC).

Sangster T, Maltas J, Struwe P, Hillier J, Boterman M, Doig M, Breda M, Garofolo F, Caturla MC, Couerbe P, Schiebl C, Pattison C, Goodwin L, Segers R, Garofolo W, Folguera L, Zimmer D, Zimmerman T, Pawula M, Tang D, Cox C, Bigogno C, Schoutsen D, de Boer T, Green R, Houghton R, Sable R, Siethoff C, Harter T, Best S; Global CRO Council for Bioanalysis (GCC).

Bioanalysis. 2012 Jul;4(14):1723-30. doi: 10.4155/BIO.12.172. No abstract available.

46.

Serum adipokines in osteoarthritis; comparison with controls and relationship with local parameters of synovial inflammation and cartilage damage.

de Boer TN, van Spil WE, Huisman AM, Polak AA, Bijlsma JW, Lafeber FP, Mastbergen SC.

Osteoarthritis Cartilage. 2012 Aug;20(8):846-53. doi: 10.1016/j.joca.2012.05.002. Epub 2012 May 14.

47.

Recommendations on the interpretation of the new European Medicines Agency Guideline on Bioanalytical Method Validation by Global CRO Council for Bioanalysis (GCC).

Boterman M, Doig M, Breda M, Lowes S, Jersey J, Shoup R, Garofolo F, Dumont I, Martinez S, Needham S, Cruz Caturla M, Couerbe P, Guittard J, Maltas J, Lansing T, Bhatti M, Schiebl C, Struwe P, Sheldon C, Hayes R, Sangster T, Pattison C, Bouchard J, Goodwin L, Islam R, Segers R, Lin ZJ, Hillier J, Garofolo W, Zimmer D, Folguera L, Zimmermann T, Pawula M, Moussallie M, Teixeira Lde S, Rocha T, Tang D, Jardieu P, Truog J, Lin J, Lundberg R, Cox C, Breau A, Bigogno C, Schoutsen D, Dilger C, Bouhajib M, Levesque A, Gagnon-Carignan S, Nicholson R, Jenkins R, Lin MH, Karnik S, De Boer T, Houghton R, Green R, DeMaio W, Sable R, Smith K, Siethoff C, Cojocaru L, Allen M, Harter T, Fatmi S, Sayyarpour F, Malone M, Best S, Fang X.

Bioanalysis. 2012 Mar;4(6):651-60. doi: 10.4155/bio.12.18. No abstract available.

48.

Experimental Mapping of the Canine KCNJ2 and KCNJ12 Gene Structures and Functional Analysis of the Canine K(IR)2.2 ion Channel.

Houtman MJ, Takanari H, Kok BG, van Eck M, Montagne DR, Vos MA, de Boer TP, van der Heyden MA.

Front Physiol. 2012 Jan 30;3:9. doi: 10.3389/fphys.2012.00009. eCollection 2012.

49.

Application of human stem cell-derived cardiomyocytes in safety pharmacology requires caution beyond hERG.

Jonsson MK, Vos MA, Mirams GR, Duker G, Sartipy P, de Boer TP, van Veen TA.

J Mol Cell Cardiol. 2012 May;52(5):998-1008. doi: 10.1016/j.yjmcc.2012.02.002. Epub 2012 Feb 14.

PMID:
22353256
50.

Development and validation of automated SPE-HPLC-MS/MS methods for the quantification of asenapine, a new antipsychotic agent, and its two major metabolites in human urine.

de Boer T, Meulman E, Meijering H, Wieling J, Dogterom P, Lass H.

Biomed Chromatogr. 2012 Dec;26(12):1461-3. doi: 10.1002/bmc.2722. Epub 2012 Feb 16.

PMID:
22344545

Supplemental Content

Loading ...
Support Center