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Impact of Older Age and Comorbidity on Locoregional and Distant Breast Cancer Recurrence: A Large Population-Based Study.

de Boer AZ, van der Hulst HC, de Glas NA, Marang-van de Mheen PJ, Siesling S, de Munck L, de Ligt KM, Portielje JEA, Bastiaannet E, Liefers GJ.

Oncologist. 2019 Sep 12. pii: theoncologist.2019-0412. doi: 10.1634/theoncologist.2019-0412. [Epub ahead of print]


Differential effects on out-of-hospital cardiac arrest of dihydropyridines: real-world data from population-based cohorts across two European countries.

Eroglu TE, Mohr GH, Blom MT, Verkerk AO, Souverein PC, Torp-Pedersen C, Folke F, Wissenberg M, van den Brink L, Davis RP, de Boer A, Gislason GH, Tan HL.

Eur Heart J Cardiovasc Pharmacother. 2019 Aug 10. pii: pvz038. doi: 10.1093/ehjcvp/pvz038. [Epub ahead of print]


A Genotype-Guided Strategy for Oral P2Y12 Inhibitors in Primary PCI.

Claassens DMF, Vos GJA, Bergmeijer TO, Hermanides RS, van 't Hof AWJ, van der Harst P, Barbato E, Morisco C, Tjon Joe Gin RM, Asselbergs FW, Mosterd A, Herrman JR, Dewilde WJM, Janssen PWA, Kelder JC, Postma MJ, de Boer A, Boersma C, Deneer VHM, Ten Berg JM.

N Engl J Med. 2019 Sep 3. doi: 10.1056/NEJMoa1907096. [Epub ahead of print]


Renal sinus fat and renal hemodynamics: a cross-sectional analysis.

Spit KA, Muskiet MHA, Tonneijck L, Smits MM, Kramer MHH, Joles JA, de Boer A, van Raalte DH.

MAGMA. 2019 Aug 31. doi: 10.1007/s10334-019-00773-z. [Epub ahead of print]


Effectiveness of radiotherapy after breast-conserving surgery in older patients with T1-2N0 breast cancer.

de Boer AZ, Bastiaannet E, de Glas NA, Marang-van de Mheen PJ, Dekkers OM, Siesling S, de Munck L, de Ligt KM, Portielje JEA, Liefers GJ.

Breast Cancer Res Treat. 2019 Aug 26. doi: 10.1007/s10549-019-05412-8. [Epub ahead of print]


Arctic closure as a trigger for Atlantic overturning at the Eocene-Oligocene Transition.

Hutchinson DK, Coxall HK, OʹRegan M, Nilsson J, Caballero R, de Boer AM.

Nat Commun. 2019 Aug 22;10(1):3797. doi: 10.1038/s41467-019-11828-z.


Risk of Nephrotic Syndrome for Non-Steroidal Anti-Inflammatory Drug Users.

Bakhriansyah M, Souverein PC, van den Hoogen MWF, de Boer A, Klungel OH.

Clin J Am Soc Nephrol. 2019 Sep 6;14(9):1355-1362. doi: 10.2215/CJN.14331218. Epub 2019 Aug 15.


Scientific assessments in European food law: Making it future-proof.

de Boer A.

Regul Toxicol Pharmacol. 2019 Aug 3;108:104437. doi: 10.1016/j.yrtph.2019.104437. [Epub ahead of print] Review.


Amiodarone use and the risk of acute pancreatitis: Influence of different exposure definitions.

Hempenius M, Groenwold RHH, de Boer A, Klungel OH, Gardarsdottir H.

Pharmacoepidemiol Drug Saf. 2019 Aug 2. doi: 10.1002/pds.4851. [Epub ahead of print]


Measuring the impact of pharmacovigilance activities, challenging but important.

van Hunsel F, Gardarsdottir H, de Boer A, Kant A.

Br J Clin Pharmacol. 2019 Jul 31. doi: 10.1111/bcp.14042. [Epub ahead of print] No abstract available.


Improved survival of older patients with advanced breast cancer due to an increase in systemic treatments: a population-based study.

de Glas N, Bastiaannet E, de Boer A, Siesling S, Liefers GJ, Portielje J.

Breast Cancer Res Treat. 2019 Jul 19. doi: 10.1007/s10549-019-05356-z. [Epub ahead of print]


Reduction of ephrin-A5 aggravates disease progression in amyotrophic lateral sclerosis.

Rué L, Oeckl P, Timmers M, Lenaerts A, van der Vos J, Smolders S, Poppe L, de Boer A, Van Den Bosch L, Van Damme P, Weishaupt JH, Ludolph AC, Otto M, Robberecht W, Lemmens R.

Acta Neuropathol Commun. 2019 Jul 12;7(1):114. doi: 10.1186/s40478-019-0759-6.


Pharmacokinetics and tolerability of inhaled levodopa from a new dry-powder inhaler in patients with Parkinson's disease.

Luinstra M, Rutgers W, van Laar T, Grasmeijer F, Begeman A, Isufi V, Steenhuis L, Hagedoorn P, de Boer A, Frijlink HW.

Ther Adv Chronic Dis. 2019 Jun 21;10:2040622319857617. doi: 10.1177/2040622319857617. eCollection 2019.


A limited number of medicines pragmatic trials had potential for waived informed consent following the 2016 CIOMS ethical guidelines.

Dal-Ré R, Avendaño-Solà C, de Boer A, James SK, Rosendaal FR, Stephens R, Ioannidis JPA.

J Clin Epidemiol. 2019 Jun 15;114:60-71. doi: 10.1016/j.jclinepi.2019.06.007. [Epub ahead of print]


Obtaining person-related information from employees with chronic health problems: a focus group study.

de Wit M, Wind H, Hulshof CTJ, de Boer AGEM.

Int Arch Occup Environ Health. 2019 May 18. doi: 10.1007/s00420-019-01440-5. [Epub ahead of print]


Informal caregivers' judgements on sharing care with home care professionals from an intersectional perspective: the influence of personal and situational characteristics.

Wittenberg Y, de Boer A, Plaisier I, Verhoeff A, Kwekkeboom R.

Scand J Caring Sci. 2019 Apr 29. doi: 10.1111/scs.12699. [Epub ahead of print] Review.


In-Flight Observation of Positron Annihilation by ILDAS.

Kochkin P, Sarria D, Skeie C, van Deursen APJ, de Boer AI, Bardet M, Allasia C, Flourens F, Østgaard N.

J Geophys Res Atmos. 2018 Aug 16;123(15):8074-8090. doi: 10.1029/2018JD028337. Epub 2018 Aug 3.


A qualitative study investigating the meaning of participation to improve the measurement of this construct.

de Wind A, van der Beek AJ, Boezeman EJ, Swenneker R, Anema JR, de Boer AGEM, Beckerman H, Hoving JL, Nieuwenhuijsen K, Scharn M, Stam M, Terwee CB, Frings-Dresen MHW, Tamminga SJ.

Qual Life Res. 2019 Aug;28(8):2233-2246. doi: 10.1007/s11136-019-02179-9. Epub 2019 Apr 16.


How Is End-of-Life Care With and Without Dementia Associated With Informal Caregivers' Outcomes?

Boogaard JA, van der Steen JT, de Boer AH, van Groenou MIB.

Am J Hosp Palliat Care. 2019 Nov;36(11):1008-1015. doi: 10.1177/1049909119836932. Epub 2019 Apr 14.


Analysis of Arabidopsis thaliana HKT1 and Eutrema salsugineum/botschantzevii HKT1;2 Promoters in Response to Salt Stress in Athkt1:1 Mutant.

Nawaz I, Iqbal M, Hakvoort HWJ, de Boer AH, Schat H.

Mol Biotechnol. 2019 Jun;61(6):442-450. doi: 10.1007/s12033-019-00175-5.


Conditional Financing of Drugs in the Netherlands: Past, Present, and Future-Results From Stakeholder Interviews.

Makady A, van Acker S, Nijmeijer H, de Boer A, Hillege H, Klungel O, Goettsch W.

Value Health. 2019 Apr;22(4):399-407. doi: 10.1016/j.jval.2018.11.016.


Risk of myocardial infarction associated with non-steroidal anti-inflammatory drugs: Impact of additional confounding control for variables collected from self-reported data.

Bakhriansyah M, Souverein PC, de Boer A, Klungel OH.

J Clin Pharm Ther. 2019 Aug;44(4):623-631. doi: 10.1111/jcpt.12836. Epub 2019 Apr 7.


Low risk pragmatic trials do not always require participants' informed consent.

Dal-Ré R, Avendaño-Solà C, Bloechl-Daum B, de Boer A, Eriksson S, Fuhr U, Holm S, James SK, Mentz RJ, Perucca E, Rosendaal FR, Treweek S.

BMJ. 2019 Mar 27;364:l1092. doi: 10.1136/bmj.l1092. No abstract available. Erratum in: BMJ. 2019 Apr 1;365:l1518.


Work cessation after cancer diagnosis: a population-based study.

Rottenberg Y, Amir Z, De Boer AGEM.

Occup Med (Lond). 2019 Apr 13;69(2):126-132. doi: 10.1093/occmed/kqz013.


Cyclo-oxygenase selectivity and chemical groups of nonsteroidal anti-inflammatory drugs and the frequency of reporting hypersensitivity reactions: a case/noncase study in VigiBase.

Bakhriansyah M, Meyboom RHB, Souverein PC, de Boer A, Klungel OH.

Fundam Clin Pharmacol. 2019 Oct;33(5):589-600. doi: 10.1111/fcp.12463. Epub 2019 Apr 22.


Heterozygous Deletion of EphrinA5 Does Not Improve Functional Recovery After Experimental Stroke.

de Boer A, Storm A, Rué L, Poppe L, Robberecht W, Lemmens R.

Stroke. 2019 Apr;50(4):e101. doi: 10.1161/STROKEAHA.118.023857. No abstract available.


Melancholia as Predictor of Electroconvulsive Therapy Outcome in Later Life.

Veltman EM, de Boer A, Dols A, van Exel E, Stek ML, Sienaert P, Bouckaert F, van der Mast R, Rhebergen D.

J ECT. 2019 Mar 5. doi: 10.1097/YCT.0000000000000579. [Epub ahead of print]


Two-Year Follow-Up of a Multi-centre Randomized Controlled Trial to Study Effectiveness of a Hospital-Based Work Support Intervention for Cancer Patients.

Tamminga SJ, Verbeek JHAM, Bos MMEM, Fons G, Kitzen JJEM, Plaisier PW, Frings-Dresen MHW, de Boer AGEM.

J Occup Rehabil. 2019 Feb 16. doi: 10.1007/s10926-019-09831-8. [Epub ahead of print]


Factors associated with an adverse work outcome in breast cancer survivors 5-10 years after diagnosis: a cross-sectional study.

Tamminga SJ, Coenen P, Paalman C, de Boer AGEM, Aaronson NK, Oldenburg HSA, van Leeuwen FE, van der Beek AJ, Duijts SFA, Schaapveld M.

J Cancer Surviv. 2019 Feb;13(1):108-116. doi: 10.1007/s11764-018-0731-7. Epub 2019 Jan 14.


The effect of active and passive peer encouragement on adolescent risk-taking.

Harakeh Z, de Boer A.

J Adolesc. 2019 Feb;71:10-17. doi: 10.1016/j.adolescence.2018.12.004. Epub 2018 Dec 21.


Effect of CYP4F2, VKORC1, and CYP2C9 in Influencing Coumarin Dose: A Single-Patient Data Meta-Analysis in More Than 15,000 Individuals.

Danese E, Raimondi S, Montagnana M, Tagetti A, Langaee T, Borgiani P, Ciccacci C, Carcas AJ, Borobia AM, Tong HY, Dávila-Fajardo C, Rodrigues Botton M, Bourgeois S, Deloukas P, Caldwell MD, Burmester JK, Berg RL, Cavallari LH, Drozda K, Huang M, Zhao LZ, Cen HJ, Gonzalez-Conejero R, Roldan V, Nakamura Y, Mushiroda T, Gong IY, Kim RB, Hirai K, Itoh K, Isaza C, Beltrán L, Jiménez-Varo E, Cañadas-Garre M, Giontella A, Kringen MK, Haug KBF, Gwak HS, Lee KE, Minuz P, Lee MTM, Lubitz SA, Scott S, Mazzaccara C, Sacchetti L, Genç E, Özer M, Pathare A, Krishnamoorthy R, Paldi A, Siguret V, Loriot MA, Kutala VK, Suarez-Kurtz G, Perini J, Denny JC, Ramirez AH, Mittal B, Rathore SS, Sagreiya H, Altman R, Shahin MHA, Khalifa SI, Limdi NA, Rivers C, Shendre A, Dillon C, Suriapranata IM, Zhou HH, Tan SL, Tatarunas V, Lesauskaite V, Zhang Y, Maitland-van der Zee AH, Verhoef TI, de Boer A, Taljaard M, Zambon CF, Pengo V, Zhang JE, Pirmohamed M, Johnson JA, Fava C.

Clin Pharmacol Ther. 2019 Jun;105(6):1477-1491. doi: 10.1002/cpt.1323. Epub 2019 Feb 17.


Social media as a tool for assessing patient perspectives on quality of life in metastatic melanoma: a feasibility study.

Makady A, Kalf RRJ, Ryll B, Spurrier G, de Boer A, Hillege H, Klungel OH, Goettsch W; GetReal Workpackage 1.

Health Qual Life Outcomes. 2018 Nov 29;16(1):222. doi: 10.1186/s12955-018-1047-z.


Effectiveness and safety of reduced-dose fluoropyrimidine therapy in patients carrying the DPYD*2A variant: A matched pair analysis.

Henricks LM, van Merendonk LN, Meulendijks D, Deenen MJ, Beijnen JH, de Boer A, Cats A, Schellens JHM.

Int J Cancer. 2019 May 1;144(9):2347-2354. doi: 10.1002/ijc.32022. Epub 2019 Jan 4.


Barriers to and Facilitators of Implementing Programs for Return to Work (RTW) of Cancer Survivors in Four European Countries: A Qualitative Study.

Tamminga SJ, Braspenning AM, Haste A, Sharp L, Frings-Dresen MHW, de Boer AGEM.

J Occup Rehabil. 2019 Sep;29(3):550-559. doi: 10.1007/s10926-018-9818-2.


Differences in self-rated health and work ability between self-employed workers and employees: Results from a prospective cohort study in the Netherlands.

Sewdas R, Tamminga SJ, Boot CRL, van den Heuvel SG, de Boer AG, van der Beek AJ.

PLoS One. 2018 Nov 12;13(11):e0206618. doi: 10.1371/journal.pone.0206618. eCollection 2018.


Longitudinal Associations Between Fatigue and Perceived Work Ability in Cancer Survivors.

Wolvers MDJ, Leensen MCJ, Groeneveld IF, Frings-Dresen MHW, De Boer AGEM.

J Occup Rehabil. 2019 Sep;29(3):540-549. doi: 10.1007/s10926-018-9814-6.


Trends in moderate and severe exacerbations among COPD patients in the UK from 2005 to 2013.

Oshagbemi OA, Keene SJ, Driessen JHM, Jordan R, Wouters EFM, de Boer A, de Vries F, Franssen FME.

Respir Med. 2018 Nov;144:1-6. doi: 10.1016/j.rmed.2018.09.010. Epub 2018 Sep 17.


Male and Female Partner-Caregivers' Burden: Does It Get Worse Over Time?

Swinkels JC, Broese van Groenou MI, de Boer A, Tilburg TGV.

Gerontologist. 2018 Oct 12. doi: 10.1093/geront/gny132. [Epub ahead of print]


Implementing managed entry agreements in practice: The Dutch reality check.

Makady A, van Veelen A, de Boer A, Hillege H, Klungel OH, Goettsch W.

Health Policy. 2019 Mar;123(3):267-274. doi: 10.1016/j.healthpol.2018.09.016. Epub 2018 Sep 28.


The Quality of Working Life Questionnaire for Cancer Survivors: Sufficient responsiveness for use as a patient-reported outcome measurement.

Tamminga SJ, de Jong M, Frings-Dresen MHW, de Boer AGEM.

Eur J Cancer Care (Engl). 2018 Nov;27(6):e12910. doi: 10.1111/ecc.12910. Epub 2018 Sep 4.


Use of proton pump inhibitors and risk of iron deficiency: a population-based case-control study.

Tran-Duy A, Connell NJ, Vanmolkot FH, Souverein PC, de Wit NJ, Stehouwer CDA, Hoes AW, de Vries F, de Boer A.

J Intern Med. 2019 Feb;285(2):205-214. doi: 10.1111/joim.12826. Epub 2018 Sep 17.


Magnetic resonance imaging T1- and T2-mapping to assess renal structure and function: a systematic review and statement paper.

Wolf M, de Boer A, Sharma K, Boor P, Leiner T, Sunder-Plassmann G, Moser E, Caroli A, Jerome NP.

Nephrol Dial Transplant. 2018 Sep 1;33(suppl_2):ii41-ii50. doi: 10.1093/ndt/gfy198.


Prognostic factors for return to work and work disability among colorectal cancer survivors; A systematic review.

den Bakker CM, Anema JR, Zaman AGNM, de Vet HCW, Sharp L, Angenete E, Allaix ME, Otten RHJ, Huirne JAF, Bonjer HJ, de Boer AGEM, Schaafsma FG.

PLoS One. 2018 Aug 15;13(8):e0200720. doi: 10.1371/journal.pone.0200720. eCollection 2018.


Non-steroidal anti-inflammatory drugs and the risk of out-of-hospital cardiac arrest: a case-control study.

Bakhriansyah M, Souverein PC, Klungel OH, de Boer A, Blom MT, Tan HL.

Europace. 2019 Jan 1;21(1):99-105. doi: 10.1093/europace/euy180. Erratum in: Europace. 2019 Jan 1;21(1):105.


Employees Diagnosed with Cancer: Current Perspectives and Future Directions from an Employer's Point of View.

Tamminga SJ, Wolvers MDJ, Greidanus MA, Zaman AGNM, Braspenning AM, Frings-Dresen MHW, de Boer AGEM.

J Occup Rehabil. 2019 Jun;29(2):472-474. doi: 10.1007/s10926-018-9802-x.


Combined use of polypill components in patients with type 2 diabetes mellitus.

Janssen VE, Visseren FL, de Boer A, Grobbee DE, Westerink J, van der Graaf Y, Lafeber M; SMART Study Group.

Eur J Prev Cardiol. 2018 Sep;25(14):1523-1531. doi: 10.1177/2047487318789494. Epub 2018 Jul 23.


What Employer Actions Are Considered Most Important for the Return to Work of Employees with Cancer? A Delphi Study Among Employees and Employers.

Greidanus MA, Tamminga SJ, de Rijk AE, Frings-Dresen MHW, de Boer AGEM.

J Occup Rehabil. 2019 Jun;29(2):406-422. doi: 10.1007/s10926-018-9800-z.


Using a single noninferiority margin or preserved fraction for an entire pharmacological class was found to be inappropriate.

Althunian TA, de Boer A, Groenwold RHH, Klungel OH.

J Clin Epidemiol. 2018 Dec;104:15-23. doi: 10.1016/j.jclinepi.2018.07.004. Epub 2018 Aug 25.


Challenges for pulmonary delivery of high powder doses.

Sibum I, Hagedoorn P, de Boer AH, Frijlink HW, Grasmeijer F.

Int J Pharm. 2018 Sep 5;548(1):325-336. doi: 10.1016/j.ijpharm.2018.07.008. Epub 2018 Jul 2. Review.


Work-Related Outcomes in Self-Employed Cancer Survivors: A European Multi-country Study.

Torp S, Paraponaris A, Van Hoof E, Lindbohm ML, Tamminga SJ, Alleaume C, Van Campenhout N, Sharp L, de Boer AGEM.

J Occup Rehabil. 2019 Jun;29(2):361-374. doi: 10.1007/s10926-018-9792-8.


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