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Items: 30


Safety, tolerability, pharmacokinetics, and immunogenicity of a human monoclonal antibody targeting the G glycoprotein of henipaviruses in healthy adults: a first-in-human, randomised, controlled, phase 1 study.

Playford EG, Munro T, Mahler SM, Elliott S, Gerometta M, Hoger KL, Jones ML, Griffin P, Lynch KD, Carroll H, El Saadi D, Gilmour ME, Hughes B, Hughes K, Huang E, de Bakker C, Klein R, Scher MG, Smith IL, Wang LF, Lambert SB, Dimitrov DS, Gray PP, Broder CC.

Lancet Infect Dis. 2020 Feb 3. pii: S1473-3099(19)30634-6. doi: 10.1016/S1473-3099(19)30634-6. [Epub ahead of print]


Monitoring pulmonary pressures during long-term continuous-flow left ventricular assist device and fixed pulmonary hypertension: redefining alleged pathophysiological mechanisms?

De Bakker CC, Veenis JF, Manintveld OC, Constantinescu AA, Caliskan K, den Uil CA, Brugts JJ.

ESC Heart Fail. 2020 Feb 5. doi: 10.1002/ehf2.12594. [Epub ahead of print]


Mycobacterium chelonae, an 'atypical' cause of an LVAD driveline infection.

Roest S, Bax HI, Verkaik NJ, Brugts JJ, Constantinescu AA, de Bakker CC, Birim O, Caliskan K, Manintveld OC.

Int J Infect Dis. 2020 Jan 8;92:127-129. doi: 10.1016/j.ijid.2020.01.002. [Epub ahead of print]


A TetR-Family Protein (CAETHG_0459) Activates Transcription From a New Promoter Motif Associated With Essential Genes for Autotrophic Growth in Acetogens.

de Souza Pinto Lemgruber R, Valgepea K, Gonzalez Garcia RA, de Bakker C, Palfreyman RW, Tappel R, Köpke M, Simpson SD, Nielsen LK, Marcellin E.

Front Microbiol. 2019 Nov 15;10:2549. doi: 10.3389/fmicb.2019.02549. eCollection 2019.


Associations Between Breastfeeding History and Early Postmenopausal Bone Loss.

de Bakker CMJ, Burt LA, Gabel L, Hanley DA, Boyd SK.

Calcif Tissue Int. 2020 Mar;106(3):264-273. doi: 10.1007/s00223-019-00638-6. Epub 2019 Nov 30.


Mechanical Regulation of the Maternal Skeleton during Reproduction and Lactation.

Liu XS, Wang L, de Bakker CMJ, Lai X.

Curr Osteoporos Rep. 2019 Dec;17(6):375-386. doi: 10.1007/s11914-019-00555-5. Review.


Canine CD117-Specific Antibodies with Diverse Binding Properties Isolated from a Phage Display Library Using Cell-Based Biopanning.

Alfaleh MA, Arora N, Yeh M, de Bakker CJ, Howard CB, Macpherson P, Allavena RE, Chen X, Harkness L, Mahler SM, Jones ML.

Antibodies (Basel). 2019 Feb 12;8(1). pii: E15. doi: 10.3390/antib8010015.


Reproducibility and Radiation Effect of High-Resolution In Vivo Micro Computed Tomography Imaging of the Mouse Lumbar Vertebra and Long Bone.

Zhao H, Chang CC, Liu Y, Yang Y, Tseng WJ, de Bakker CM, Chung R, Ghosh P, Deng L, Liu XS.

Ann Biomed Eng. 2020 Jan;48(1):157-168. doi: 10.1007/s10439-019-02323-z. Epub 2019 Jul 29.


Structural Adaptations in the Rat Tibia Bone Induced by Pregnancy and Lactation Confer Protective Effects Against Future Estrogen Deficiency.

de Bakker CM, Li Y, Zhao H, Leavitt L, Tseng WJ, Lin T, Tong W, Qin L, Liu XS.

J Bone Miner Res. 2018 Dec;33(12):2165-2176. doi: 10.1002/jbmr.3559. Epub 2018 Aug 13.


Effects of reproduction on sexual dimorphisms in rat bone mechanics.

de Bakker CMJ, Zhao H, Tseng WJ, Li Y, Altman-Singles AR, Liu Y, Leavitt L, Liu XS.

J Biomech. 2018 Aug 22;77:40-47. doi: 10.1016/j.jbiomech.2018.06.023. Epub 2018 Jun 23.


Erratum: "BMPR1A antagonist differentially affects cartilage and bone formation during fracture healing" [J Orthop Res. Vol 34, 2096-2105 (2016)].

Morgan EF, Pittman J, DeGiacomo A, Cusher D, de Bakker CMJ, Mroszczyk KA, Grinstaff MW, Gerstenfeld LC.

J Orthop Res. 2018 Mar;36(3):1040. doi: 10.1002/jor.23677. Epub 2017 Sep 20. No abstract available.


Targeting mesothelin receptors with drug-loaded bacterial nanocells suppresses human mesothelioma tumour growth in mouse xenograft models.

Alfaleh MA, Howard CB, Sedliarou I, Jones ML, Gudhka R, Vanegas N, Weiss J, Suurbach JH, de Bakker CJ, Milne MR, Rumballe BA, MacDiarmid JA, Brahmbhatt H, Mahler SM.

PLoS One. 2017 Oct 23;12(10):e0186137. doi: 10.1371/journal.pone.0186137. eCollection 2017.


Reproduction Differentially Affects Trabecular Bone Depending on Its Mechanical Versus Metabolic Role.

de Bakker CMJ, Tseng WJ, Li Y, Zhao H, Altman-Singles AR, Jeong Y, Robberts J, Han L, Kim DG, Sherry Liu X.

J Biomech Eng. 2017 Nov 1;139(11). doi: 10.1115/1.4038110.


Response to Loucks et al.'s Comment on "Clinical Evaluation of Bone Strength and Fracture Risk".

Liu XS, de Bakker CMJ, Tseng WJ, Li Y, Zhao H.

Curr Osteoporos Rep. 2017 Aug;15(4):398. doi: 10.1007/s11914-017-0387-7. No abstract available.


Intermittent Parathyroid Hormone After Prolonged Alendronate Treatment Induces Substantial New Bone Formation and Increases Bone Tissue Heterogeneity in Ovariectomized Rats.

Altman-Singles AR, Jeong Y, Tseng WJ, de Bakker CM, Zhao H, Lott C, Robberts J, Qin L, Han L, Kim DG, Liu XS.

J Bone Miner Res. 2017 Aug;32(8):1703-1715. doi: 10.1002/jbmr.3165. Epub 2017 Jun 13.


Clinical Evaluation of Bone Strength and Fracture Risk.

de Bakker CMJ, Tseng WJ, Li Y, Zhao H, Liu XS.

Curr Osteoporos Rep. 2017 Feb;15(1):32-42. doi: 10.1007/s11914-017-0346-3. Review.


Adaptations in the Microarchitecture and Load Distribution of Maternal Cortical and Trabecular Bone in Response to Multiple Reproductive Cycles in Rats.

de Bakker CM, Altman-Singles AR, Li Y, Tseng WJ, Li C, Liu XS.

J Bone Miner Res. 2017 May;32(5):1014-1026. doi: 10.1002/jbmr.3084. Epub 2017 Feb 9.


Biosimilars approved for treatment of inflammatory rheumatological diseases.

Mahler SM, Wardiana A, Jones ML, de Bakker CJ, Graham GG, Howard CB.

Int J Rheum Dis. 2016 Nov;19(11):1043-1048. doi: 10.1111/1756-185X.13037. No abstract available.


Beyond Antibodies: Development of a Novel Protein Scaffold Based on Human Chaperonin 10.

Alsultan AM, Chin DY, Howard CB, de Bakker CJ, Jones ML, Mahler SM.

Sci Rep. 2016 Nov 22;5:37348. doi: 10.1038/srep37348.


Overcoming Instability of Antibody-Nanomaterial Conjugates: Next Generation Targeted Nanomedicines Using Bispecific Antibodies.

Howard CB, Fletcher N, Houston ZH, Fuchs AV, Boase NR, Simpson JD, Raftery LJ, Ruder T, Jones ML, de Bakker CJ, Mahler SM, Thurecht KJ.

Adv Healthc Mater. 2016 Aug;5(16):2055-68. doi: 10.1002/adhm.201600263. Epub 2016 Jun 10.


BMPR1A antagonist differentially affects cartilage and bone formation during fracture healing.

Morgan EF, Pittman J, DeGiacomo A, Cusher D, de Bakker CM, Mroszczyk KA, Grinstaff MW, Gerstenfeld LC.

J Orthop Res. 2016 Dec;34(12):2096-2105. doi: 10.1002/jor.23233. Epub 2016 Apr 6. Erratum in: J Orthop Res. 2018 Mar;36(3):1040.


Minimizing Interpolation Bias and Precision Error in In Vivo µCT-Based Measurements of Bone Structure and Dynamics.

de Bakker CMJ, Altman AR, Li C, Tribble MB, Lott C, Tseng WJ, Liu XS.

Ann Biomed Eng. 2016 Aug;44(8):2518-2528. doi: 10.1007/s10439-015-1527-9. Epub 2016 Jan 19.


Quantification of skeletal growth, modeling, and remodeling by in vivo micro computed tomography.

Altman AR, Tseng WJ, de Bakker CMJ, Chandra A, Lan S, Huh BK, Luo S, Leonard MB, Qin L, Liu XS.

Bone. 2015 Dec;81:370-379. doi: 10.1016/j.bone.2015.07.037. Epub 2015 Aug 6.


μCT-based, in vivo dynamic bone histomorphometry allows 3D evaluation of the early responses of bone resorption and formation to PTH and alendronate combination therapy.

de Bakker CM, Altman AR, Tseng WJ, Tribble MB, Li C, Chandra A, Qin L, Liu XS.

Bone. 2015 Apr;73:198-207. doi: 10.1016/j.bone.2014.12.061. Epub 2014 Dec 30.


Enhanced individual trabecular repair and its mechanical implications in parathyroid hormone and alendronate treated rat tibial bone.

Altman AR, de Bakker CM, Tseng WJ, Chandra A, Qin L, Liu XS.

J Biomech Eng. 2015 Jan;137(1). doi: 10.1115/1.4028823. Epub 2014 Dec 10.


A closer look at the immediate trabecula response to combined parathyroid hormone and alendronate treatment.

Altman AR, Tseng WJ, de Bakker CM, Huh BK, Chandra A, Qin L, Liu XS.

Bone. 2014 Apr;61:149-57. doi: 10.1016/j.bone.2014.01.008. Epub 2014 Jan 24.


Assessment of contrast-enhanced computed tomography for imaging of cartilage during fracture healing.

Hayward LN, de Bakker CM, Gerstenfeld LC, Grinstaff MW, Morgan EF.

J Orthop Res. 2013 Apr;31(4):567-73. doi: 10.1002/jor.22265. Epub 2012 Nov 19.


MRT letter: Contrast-enhanced computed tomographic imaging of soft callus formation in fracture healing.

Hayward LN, de Bakker CM, Lusic H, Gerstenfeld LC, Grinstaff MW, Morgan EF.

Microsc Res Tech. 2012 Jan;75(1):7-14. doi: 10.1002/jemt.21100. Epub 2011 Oct 28.


Evaluation of 111In labelled white blood cells by in vitro functional tests and electron microscopy. Comparison of three labelling methods.

Mortelmans L, Verbruggen A, Malbrain S, Heynen MJ, de Bakker C, Boogaerts M, de Roo M.

Eur J Nucl Med. 1988;14(3):159-64.


Comparison of quantification methods of 111In-labelled platelet deposition in peripheral bypass grafts.

Mortelmans L, Verbruggen A, De Bakker C, Vandecruys A, Joosten J, Nevelsteen A, Noyez L, Verstraete M, Vermylen J, De Roo M.

Nuklearmedizin. 1987 Apr;26(2):87-92.


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