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Items: 29


A Suite of Transgenic Driver and Reporter Mouse Lines with Enhanced Brain-Cell-Type Targeting and Functionality.

Daigle TL, Madisen L, Hage TA, Valley MT, Knoblich U, Larsen RS, Takeno MM, Huang L, Gu H, Larsen R, Mills M, Bosma-Moody A, Siverts LA, Walker M, Graybuck LT, Yao Z, Fong O, Nguyen TN, Garren E, Lenz GH, Chavarha M, Pendergraft J, Harrington J, Hirokawa KE, Harris JA, Nicovich PR, McGraw MJ, Ollerenshaw DR, Smith KA, Baker CA, Ting JT, Sunkin SM, Lecoq J, Lin MZ, Boyden ES, Murphy GJ, da Costa NM, Waters J, Li L, Tasic B, Zeng H.

Cell. 2018 Jul 12;174(2):465-480.e22. doi: 10.1016/j.cell.2018.06.035.


Esophageal squamous cell carcinoma transcriptome reveals the effect of FOXM1 on patient outcome through novel PIK3R3 mediated activation of PI3K signaling pathway.

Nicolau-Neto P, Da Costa NM, de Souza Santos PT, Gonzaga IM, Ferreira MA, Guaraldi S, Moreira MA, Seuánez HN, Brewer L, Bergmann A, Boroni M, Mencalha AL, Kruel CDP, Lima SCS, Esposito D, Simão TA, Pinto LFR.

Oncotarget. 2018 Mar 30;9(24):16634-16647. doi: 10.18632/oncotarget.24621. eCollection 2018 Mar 30.


TFF1 hypermethylation and decreased expression in esophageal squamous cell carcinoma and histologically normal tumor surrounding esophageal cells.

Gonzaga IM, Soares Lima SC, Nicolau MC, Nicolau-Neto P, da Costa NM, de Almeida Simão T, Hernandez-Vargas H, Herceg Z, Ribeiro Pinto LF.

Clin Epigenetics. 2017 Dec 20;9:130. doi: 10.1186/s13148-017-0429-0. eCollection 2017.


Chronic exposure to inorganic mercury induces biochemical and morphological changes in the salivary glands of rats.

Aragão WAB, da Costa NMM, Fagundes NCF, Silva MCF, Alves-Junior SM, Pinheiro JJV, Amado LL, Crespo-López ME, Maia CSF, Lima RR.

Metallomics. 2017 Sep 20;9(9):1271-1278. doi: 10.1039/c7mt00123a.


Prostate cancer molecular profiling: the Achilles heel for the implementation of precision medicine.

Oliveira-Barros EG, Nicolau-Neto P, Da Costa NM, Pinto LFR, Palumbo A Jr, Nasciutti LE.

Cell Biol Int. 2017 Nov;41(11):1239-1245. doi: 10.1002/cbin.10785. Epub 2017 May 18. Review.


Fast assembling of neuron fragments in serial 3D sections.

Chen H, Iascone DM, da Costa NM, Lein ES, Liu T, Peng H.

Brain Inform. 2017 Sep;4(3):183-186. doi: 10.1007/s40708-017-0063-9. Epub 2017 Apr 1.


Role of HIF-1α and CASPASE-3 in cystogenesis of odontogenic cysts and tumors.

da Costa NMM, de Siqueira AS, Ribeiro ALR, da Silva Kataoka MS, Jaeger RG, de Alves-Júnior SM, Smith AM, de Jesus Viana Pinheiro J.

Clin Oral Investig. 2018 Jan;22(1):141-149. doi: 10.1007/s00784-017-2090-6. Epub 2017 Feb 25.


Maternal protein restriction during lactation modulated the expression and activity of rat offspring hepatic CYP1A1, CYP1A2, CYP2B1, CYP2B2, and CYP2E1 during development.

Da Costa NM, Visoni SB, Dos Santos IL, Barja-Fidalgo TC, Ribeiro-Pinto LF.

Braz J Med Biol Res. 2016;49(11):e5238. Epub 2016 Nov 3.


UBE2C is overexpressed in ESCC tissues and its abrogation attenuates the malignant phenotype of ESCC cell lines.

Palumbo A Jr, Da Costa NM, De Martino M, Sepe R, Pellecchia S, de Sousa VP, Nicolau Neto P, Kruel CD, Bergman A, Nasciutti LE, Fusco A, Pinto LF.

Oncotarget. 2016 Oct 4;7(40):65876-65887. doi: 10.18632/oncotarget.11674.


Keratocystic odontogenic tumor overexpresses invadopodia-related proteins, suggesting invadopodia formation.

Ribeiro Ribeiro AL, da Costa NM, de Siqueira AS, Brasil da Silva W, da Silva Kataoka MS, Jaeger RG, de Melo Alves-Junior S, Smith AM, de Jesus Viana Pinheiro J.

Oral Surg Oral Med Oral Pathol Oral Radiol. 2016 Oct;122(4):500-8. doi: 10.1016/j.oooo.2016.06.004. Epub 2016 Jun 22.


High Mobility Group A proteins in esophageal carcinomas.

Palumbo Júnior A, Da Costa NM, Esposito F, Fusco A, Pinto LF.

Cell Cycle. 2016 Sep 16;15(18):2410-3. doi: 10.1080/15384101.2016.1215388. Epub 2016 Aug 2.


HMGA2 overexpression plays a critical role in the progression of esophageal squamous carcinoma.

Palumbo A Jr, Da Costa NM, Esposito F, De Martino M, D'Angelo D, de Sousa VP, Martins I, Nasciutti LE, Fusco A, Ribeiro Pinto LF.

Oncotarget. 2016 May 3;7(18):25872-84. doi: 10.18632/oncotarget.8288.


Aberrant levels of Wnt/β-catenin pathway components in a rat model of endometriosis.

de Mattos RM, Pereira PR, Barros EG, da Silva JH, Palmero CY, da Costa NM, Pinto LF, Gimba ER, Hecht F, Ferreira LB, Machado DE, de Oliveira FL, Nasciutti LE.

Histol Histopathol. 2016 Aug;31(8):933-42. doi: 10.14670/HH-11-730. Epub 2016 Feb 8.


Role of hypoxia-related proteins in invasion of ameloblastoma cells: crosstalk between NOTCH1, hypoxia-inducible factor 1α, a disintegrin and metalloproteinase 12, and heparin-binding epidermal growth factor.

da Costa NM, Fialho AD, Proietti CC, da Silva Kataoka MS, Jaeger RG, de Alves-Júnior SM, de Jesus Viana Pinheiro J.

Histopathology. 2016 Jul;69(1):99-106. doi: 10.1111/his.12922. Epub 2016 Feb 25.


Morphological aspects and physical properties of enamel and dentine of Sus domesticus: A tooth model in laboratory research.

Fagundes NC, Cardoso MA, Miranda MS, Silva Rde B, Teixeira FB, Nogueira BC, Nogueira BM, de Melo SE, da Costa NM, Lima RR.

Ann Anat. 2015 Nov;202:71-7. doi: 10.1016/j.aanat.2015.08.007. Epub 2015 Sep 21.


Physical, chemical, and immunohistochemical investigation of the damage to salivary glands in a model of intoxication with aluminium citrate.

da Costa NM, Correa RS, Júnior IS, Figueiredo AJ, Vilhena KF, Farias-Junior PM, Teixeira FB, Ferreira NM, Pereira-Júnior JB, Dantas Kd, da Silva MC, Silva-Junior AF, Alves-Junior Sde M, Pinheiro Jde J, Lima RR.

Int J Environ Res Public Health. 2014 Nov 28;11(12):12429-40. doi: 10.3390/ijerph111212429.


The reciprocal interactions between astrocytes and prostate cancer cells represent an early event associated with brain metastasis.

de Oliveira Barros EG, Palumbo A Jr, Mello PL, de Mattos RM, da Silva JH, Pontes B, Viana NB, do Amaral RF, Lima FR, da Costa NM, Palmero CY, Miranda-Alves L, Takiya CM, Nasciutti LE.

Clin Exp Metastasis. 2014 Apr;31(4):461-74. doi: 10.1007/s10585-014-9640-y. Epub 2014 Feb 1.


The potential of molecular markers to improve interventions through the natural history of oesophageal squamous cell carcinoma.

da Costa NM, Soares Lima SC, de Almeida Simão T, Ribeiro Pinto LF.

Biosci Rep. 2013 Aug 14;33(4). pii: e00057. doi: 10.1042/BSR20130063. Review.


Sparse reconstruction of brain circuits: or, how to survive without a microscopic connectome.

da Costa NM, Martin KA.

Neuroimage. 2013 Oct 15;80:27-36. doi: 10.1016/j.neuroimage.2013.04.054. Epub 2013 Apr 25.


Diversity of thalamorecipient spine morphology in cat visual cortex and its implication for synaptic plasticity.

da Costa NM.

J Comp Neurol. 2013 Jun 15;521(9):2058-66. doi: 10.1002/cne.23272.


Transcriptional regulation of thymine DNA glycosylase (TDG) by the tumor suppressor protein p53.

da Costa NM, Hautefeuille A, Cros MP, Melendez ME, Waters T, Swann P, Hainaut P, Pinto LF.

Cell Cycle. 2012 Dec 15;11(24):4570-8. doi: 10.4161/cc.22843. Epub 2012 Nov 19.


How thalamus connects to spiny stellate cells in the cat's visual cortex.

da Costa NM, Martin KA.

J Neurosci. 2011 Feb 23;31(8):2925-37. doi: 10.1523/JNEUROSCI.5961-10.2011.


Embedding of cortical representations by the superficial patch system.

Muir DR, Da Costa NM, Girardin CC, Naaman S, Omer DB, Ruesch E, Grinvald A, Douglas RJ.

Cereb Cortex. 2011 Oct;21(10):2244-60. doi: 10.1093/cercor/bhq290. Epub 2011 Mar 7.


The synaptic organization of the claustral projection to the cat's visual cortex.

da Costa NM, Fürsinger D, Martin KA.

J Neurosci. 2010 Sep 29;30(39):13166-70. doi: 10.1523/JNEUROSCI.3122-10.2010.


Whose Cortical Column Would that Be?

da Costa NM, Martin KA.

Front Neuroanat. 2010 May 31;4:16. doi: 10.3389/fnana.2010.00016. eCollection 2010.


Selective targeting of the dendrites of corticothalamic cells by thalamic afferents in area 17 of the cat.

da Costa NM, Martin KA.

J Neurosci. 2009 Nov 4;29(44):13919-28. doi: 10.1523/JNEUROSCI.2785-09.2009.


The proportion of synapses formed by the axons of the lateral geniculate nucleus in layer 4 of area 17 of the cat.

da Costa NM, Martin KA.

J Comp Neurol. 2009 Oct 1;516(4):264-76. doi: 10.1002/cne.22133.


The W cell pathway to cat primary visual cortex.

Anderson JC, da Costa NM, Martin KA.

J Comp Neurol. 2009 Sep 1;516(1):20-35. doi: 10.1002/cne.22085.


A systematic random sampling scheme optimized to detect the proportion of rare synapses in the neuropil.

da Costa NM, Hepp K, Martin KA.

J Neurosci Methods. 2009 May 30;180(1):77-81. doi: 10.1016/j.jneumeth.2009.03.001. Epub 2009 Mar 18.


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