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Items: 1 to 50 of 90

1.

Flavin homeostasis in the mouse retina during aging and degeneration.

Sinha T, Makia M, Du J, Naash MI, Al-Ubaidi MR.

J Nutr Biochem. 2018 Dec;62:123-133. doi: 10.1016/j.jnutbio.2018.09.003. Epub 2018 Sep 15.

PMID:
30290331
2.

Oligomerization of Prph2 and Rom1 is essential for photoreceptor outer segment formation.

Zulliger R, Conley SM, Mwoyosvi ML, Al-Ubaidi MR, Naash MI.

Hum Mol Genet. 2018 Oct 15;27(20):3507-3518. doi: 10.1093/hmg/ddy240.

PMID:
29961824
3.

Retbindin Is Capable of Protecting Photoreceptors from Flavin-Sensitized Light-Mediated Cell Death In Vitro.

Kelley RA, Al-Ubaidi MR, Naash MI.

Adv Exp Med Biol. 2018;1074:485-490. doi: 10.1007/978-3-319-75402-4_60.

PMID:
29721980
4.

Role of Fibulins 2 and 5 in Retinal Development and Maintenance.

Ikelle L, Naash MI, Al-Ubaidi MR.

Adv Exp Med Biol. 2018;1074:275-280. doi: 10.1007/978-3-319-75402-4_33.

PMID:
29721953
5.

Optimizing Non-viral Gene Therapy Vectors for Delivery to Photoreceptors and Retinal Pigment Epithelial Cells.

Zulliger R, Watson JN, Al-Ubaidi MR, Padegimas L, Sesenoglu-Laird O, Cooper MJ, Naash MI.

Adv Exp Med Biol. 2018;1074:109-115. doi: 10.1007/978-3-319-75402-4_14.

PMID:
29721934
6.

Ablation of the riboflavin-binding protein retbindin reduces flavin levels and leads to progressive and dose-dependent degeneration of rods and cones.

Kelley RA, Al-Ubaidi MR, Sinha T, Genc AM, Makia MS, Ikelle L, Naash MI.

J Biol Chem. 2017 Dec 22;292(51):21023-21034. doi: 10.1074/jbc.M117.785105. Epub 2017 Oct 27.

7.

Identification of Tyrosine O Sulfated Proteins in Cow Retina and the 661W Cell Line.

Kanan Y, Al-Ubaidi MR.

Adv Exp Med Biol. 2016;854:649-54. doi: 10.1007/978-3-319-17121-0_86.

PMID:
26427471
8.

The Potential Role of Flavins and Retbindin in Retinal Function and Homeostasis.

Kelley RA, Al-Ubaidi MR, Naash MI.

Adv Exp Med Biol. 2016;854:643-8. doi: 10.1007/978-3-319-17121-0_85.

PMID:
26427470
9.

Detection of tyrosine sulfation on proteins.

Kanan Y, Al Ubaidi MR.

Curr Protoc Protein Sci. 2015 Apr 1;80:14.7.1-20. doi: 10.1002/0471140864.ps1407s80.

PMID:
25829299
10.

Role of tyrosine-sulfated proteins in retinal structure and function.

Kanan Y, Al-Ubaidi MR.

Exp Eye Res. 2015 Apr;133:126-31. doi: 10.1016/j.exer.2014.07.007. Review.

11.

Genomic DNA nanoparticles rescue rhodopsin-associated retinitis pigmentosa phenotype.

Han Z, Banworth MJ, Makkia R, Conley SM, Al-Ubaidi MR, Cooper MJ, Naash MI.

FASEB J. 2015 Jun;29(6):2535-44. doi: 10.1096/fj.15-270363. Epub 2015 Feb 24.

12.

Glycosylation of rhodopsin is necessary for its stability and incorporation into photoreceptor outer segment discs.

Murray AR, Vuong L, Brobst D, Fliesler SJ, Peachey NS, Gorbatyuk MS, Naash MI, Al-Ubaidi MR.

Hum Mol Genet. 2015 May 15;24(10):2709-23. doi: 10.1093/hmg/ddv031. Epub 2015 Jan 30.

13.

Retbindin is an extracellular riboflavin-binding protein found at the photoreceptor/retinal pigment epithelium interface.

Kelley RA, Al-Ubaidi MR, Naash MI.

J Biol Chem. 2015 Feb 20;290(8):5041-52. doi: 10.1074/jbc.M114.624189. Epub 2014 Dec 25.

14.

Neuroprotectin D1 is synthesized in the cone photoreceptor cell line 661W and elicits protection against light-induced stress.

Kanan Y, Gordon WC, Mukherjee PK, Bazan NG, Al-Ubaidi MR.

Cell Mol Neurobiol. 2015 Mar;35(2):197-204. doi: 10.1007/s10571-014-0111-4. Epub 2014 Sep 12.

15.

Complement factor H, vitronectin, and opticin are tyrosine-sulfated proteins of the retinal pigment epithelium.

Kanan Y, Siefert JC, Kinter M, Al-Ubaidi MR.

PLoS One. 2014 Aug 19;9(8):e105409. doi: 10.1371/journal.pone.0105409. eCollection 2014.

16.

Yttrium oxide nanoparticles prevent photoreceptor death in a light-damage model of retinal degeneration.

Mitra RN, Merwin MJ, Han Z, Conley SM, Al-Ubaidi MR, Naash MI.

Free Radic Biol Med. 2014 Oct;75:140-8. doi: 10.1016/j.freeradbiomed.2014.07.013. Epub 2014 Jul 24.

17.

Initiation of rod outer segment disc formation requires RDS.

Chakraborty D, Conley SM, Al-Ubaidi MR, Naash MI.

PLoS One. 2014 Jun 4;9(6):e98939. doi: 10.1371/journal.pone.0098939. eCollection 2014.

18.

Rim formation is not a prerequisite for distribution of cone photoreceptor outer segment proteins.

Conley SM, Al-Ubaidi MR, Han Z, Naash MI.

FASEB J. 2014 Aug;28(8):3468-79. doi: 10.1096/fj.14-251397. Epub 2014 Apr 15.

19.

Fibulin 2, a tyrosine O-sulfated protein, is up-regulated following retinal detachment.

Kanan Y, Brobst D, Han Z, Naash MI, Al-Ubaidi MR.

J Biol Chem. 2014 May 9;289(19):13419-33. doi: 10.1074/jbc.M114.562157. Epub 2014 Apr 1.

20.

Pigment epithelium-derived factor protects cone photoreceptor-derived 661W cells from light damage through Akt activation.

Rapp M, Woo G, Al-Ubaidi MR, Becerra SP, Subramanian P.

Adv Exp Med Biol. 2014;801:813-20. doi: 10.1007/978-1-4614-3209-8_102.

PMID:
24664775
21.

RGC-5: are they really 661W? The saga continues.

Al-Ubaidi MR.

Exp Eye Res. 2014 Feb;119:115. doi: 10.1016/j.exer.2013.10.012. No abstract available.

22.

WITHDRAWN: Fibulin 2, a tyrosine o-sulfated protein, is up-regulated following retinal detachment.

Kanan Y, Brobst D, Westmuckett AD, Moore KL, Han Z, Naash MI, Al-Ubaidi MR.

J Biol Chem. 2014 Feb 26. [Epub ahead of print]

23.

A perspective on the role of the extracellular matrix in progressive retinal degenerative disorders.

Al-Ubaidi MR, Naash MI, Conley SM.

Invest Ophthalmol Vis Sci. 2013 Dec 17;54(13):8119-24. doi: 10.1167/iovs.13-13536. Review.

24.

On the use of immortalized ocular cell lines in vision research: the unfortunate story of RGC-5.

Clark A, Tamm ER, Al-Ubaidi MR, Hollyfield JG.

Exp Eye Res. 2013 Nov;116:433. doi: 10.1016/j.exer.2013.08.002. Epub 2013 Sep 7. No abstract available.

PMID:
24021353
25.

p53 selectively regulates developmental apoptosis of rod photoreceptors.

Vuong L, Brobst DE, Ivanovic I, Sherry DM, Al-Ubaidi MR.

PLoS One. 2013 Jun 20;8(6):e67381. doi: 10.1371/journal.pone.0067381. Print 2013.

26.

Differential developmental deficits in retinal function in the absence of either protein tyrosine sulfotransferase-1 or -2.

Sherry DM, Kanan Y, Hamilton R, Hoffhines A, Arbogast KL, Fliesler SJ, Naash MI, Moore KL, Al-Ubaidi MR.

PLoS One. 2012;7(6):e39702. doi: 10.1371/journal.pone.0039702. Epub 2012 Jun 22.

27.

Pattern of expression of p53, its family members, and regulators during early ocular development and in the post-mitotic retina.

Vuong L, Brobst DE, Saadi A, Ivanovic I, Al-Ubaidi MR.

Invest Ophthalmol Vis Sci. 2012 Jul 20;53(8):4821-31. doi: 10.1167/iovs.11-8681.

28.

Expression and role of p53 in the retina.

Vuong L, Conley SM, Al-Ubaidi MR.

Invest Ophthalmol Vis Sci. 2012 Mar 15;53(3):1362-71. doi: 10.1167/iovs.11-8909. Review.

PMID:
22427613
29.

Focus on molecules: sulfotyrosine.

Kanan Y, Hamilton RA, Sherry DM, Al-Ubaidi MR.

Exp Eye Res. 2012 Dec;105:85-6. doi: 10.1016/j.exer.2012.02.014. Epub 2012 Mar 1. No abstract available.

30.

Protein tyrosine-O-sulfation in bovine ocular tissues.

Kanan Y, Hamilton RA, Moore KL, Al-Ubaidi MR.

Adv Exp Med Biol. 2012;723:835-41. doi: 10.1007/978-1-4614-0631-0_107. No abstract available.

PMID:
22183414
31.

Lack of protein-tyrosine sulfation disrupts photoreceptor outer segment morphogenesis, retinal function and retinal anatomy.

Sherry DM, Murray AR, Kanan Y, Arbogast KL, Hamilton RA, Fliesler SJ, Burns ME, Moore KL, Al-Ubaidi MR.

Eur J Neurosci. 2010 Nov;32(9):1461-72. doi: 10.1111/j.1460-9568.2010.07431.x. Epub 2010 Oct 12.

32.

Photoreceptor cells constitutively express functional TLR4.

Tu Z, Portillo JA, Howell S, Bu H, Subauste CS, Al-Ubaidi MR, Pearlman E, Lin F.

J Neuroimmunol. 2011 Jan;230(1-2):183-7. doi: 10.1016/j.jneuroim.2010.07.022.

33.

A 350 bp region of the proximal promoter of Rds drives cell-type specific gene expression.

Cai X, Conley SM, Cheng T, Al-Ubaidi MR, Naash MI.

Exp Eye Res. 2010 Aug;91(2):186-94. doi: 10.1016/j.exer.2010.04.017. Epub 2010 May 4.

34.

Role of Elovl4 protein in the biosynthesis of docosahexaenoic acid.

Agbaga MP, Brush RS, Mandal MN, Elliott MH, Al-Ubaidi MR, Anderson RE.

Adv Exp Med Biol. 2010;664:233-42. doi: 10.1007/978-1-4419-1399-9_27.

35.

Analysis of genes differentially expressed during retinal degeneration in three mouse models.

Kanan Y, Centola M, Bart F, Al-Ubaidi MR.

Adv Exp Med Biol. 2010;664:3-13. doi: 10.1007/978-1-4419-1399-9_1.

PMID:
20237996
36.

Rhodopsin: the functional significance of asn-linked glycosylation and other post-translational modifications.

Murray AR, Fliesler SJ, Al-Ubaidi MR.

Ophthalmic Genet. 2009 Sep;30(3):109-20. doi: 10.1080/13816810902962405. Review. Erratum in: Ophthalmic Genet. 2010 Mar;31(1):52.

37.

Protein tyrosine-O-sulfation in the retina.

Kanan Y, Hoffhines A, Rauhauser A, Murray A, Al-Ubaidi MR.

Exp Eye Res. 2009 Oct;89(4):559-67. doi: 10.1016/j.exer.2009.05.010. Epub 2009 Jun 11.

38.

Overexpression of rhodopsin alters the structure and photoresponse of rod photoreceptors.

Wen XH, Shen L, Brush RS, Michaud N, Al-Ubaidi MR, Gurevich VV, Hamm HE, Lem J, Dibenedetto E, Anderson RE, Makino CL.

Biophys J. 2009 Feb;96(3):939-50. doi: 10.1016/j.bpj.2008.10.016.

39.

Retinol dehydrogenases RDH11 and RDH12 in the mouse retina: expression levels during development and regulation by oxidative stress.

Kanan Y, Wicker LD, Al-Ubaidi MR, Mandal NA, Kasus-Jacobi A.

Invest Ophthalmol Vis Sci. 2008 Mar;49(3):1071-8. doi: 10.1167/iovs.07-1207.

40.

Functional expression of cone cyclic nucleotide-gated channel in cone photoreceptor-derived 661W cells.

Fitzgerald JB, Malykhina AP, Al-Ubaidi MR, Ding XQ.

Adv Exp Med Biol. 2008;613:327-34. doi: 10.1007/978-0-387-74904-4_38. No abstract available.

PMID:
18188961
41.

Proteomics profiling of the cone photoreceptor cell line, 661W.

Al-Ubaidi MR, Matsumoto H, Kurono S, Singh A.

Adv Exp Med Biol. 2008;613:301-11. doi: 10.1007/978-0-387-74904-4_35. No abstract available.

PMID:
18188958
42.

An in-vivo assay to identify compounds protective against light induced apoptosis.

Kanan Y, Jacobi AK, Sawyer K, Mannel DS, Tink JT, Al-Ubaidi MR.

Adv Exp Med Biol. 2008;613:61-7. doi: 10.1007/978-0-387-74904-4_6. No abstract available.

PMID:
18188929
43.

Retinoid processing in cone and Müller cell lines.

Kanan Y, Kasus-Jacobi A, Moiseyev G, Sawyer K, Ma JX, Al-Ubaidi MR.

Exp Eye Res. 2008 Feb;86(2):344-54. doi: 10.1016/j.exer.2007.11.006. Epub 2007 Nov 17.

44.

G-protein-coupled receptor rhodopsin regulates the phosphorylation of retinal insulin receptor.

Rajala A, Anderson RE, Ma JX, Lem J, Al-Ubaidi MR, Rajala RV.

J Biol Chem. 2007 Mar 30;282(13):9865-73. Epub 2007 Feb 1.

45.

Conditional gene knockout system in cone photoreceptors.

Le YZ, Ash JD, Al-Ubaidi MR, Chen Y, Ma JX, Anderson RE.

Adv Exp Med Biol. 2006;572:173-8. Review.

PMID:
17249572
46.

Light induces programmed cell death by activating multiple independent proteases in a cone photoreceptor cell line.

Kanan Y, Moiseyev G, Agarwal N, Ma JX, Al-Ubaidi MR.

Invest Ophthalmol Vis Sci. 2007 Jan;48(1):40-51.

PMID:
17197514
47.

Deletion of smooth muscle alpha-actin alters blood-retina barrier permeability and retinal function.

Tomasek JJ, Haaksma CJ, Schwartz RJ, Vuong DT, Zhang SX, Ash JD, Ma JX, Al-Ubaidi MR.

Invest Ophthalmol Vis Sci. 2006 Jun;47(6):2693-700.

PMID:
16723488
48.

Photoreceptor cell apoptosis induced by the 2-nitroimidazole radiosensitizer, CI-1010, is mediated by p53-linked activation of caspase-3.

Miller TJ, Schneider RJ, Miller JA, Martin BP, Al-Ubaidi MR, Agarwal N, Dethloff LA, Philbert MA.

Neurotoxicology. 2006 Jan;27(1):44-59. Epub 2005 Aug 24.

PMID:
16125243
49.

Cloning, immunolocalization, and functional expression of a GABA transporter from the retina of the skate.

Birnbaum AD, Rohde SK, Qian H, Al-Ubaidi MR, Caldwell JH, Malchow RP.

Vis Neurosci. 2005 Mar-Apr;22(2):211-23.

PMID:
15935113
50.

Targeted expression of Cre recombinase to cone photoreceptors in transgenic mice.

Le YZ, Ash JD, Al-Ubaidi MR, Chen Y, Ma JX, Anderson RE.

Mol Vis. 2004 Dec 27;10:1011-8.

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