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Items: 27


Ratiometric GPCR signaling enables directional sensing in yeast.

Henderson NT, Pablo M, Ghose D, Clark-Cotton MR, Zyla TR, Nolen J, Elston TC, Lew DJ.

PLoS Biol. 2019 Oct 17;17(10):e3000484. doi: 10.1371/journal.pbio.3000484. eCollection 2019 Oct.


A role for Gic1 and Gic2 in Cdc42 polarization at elevated temperature.

Daniels CN, Zyla TR, Lew DJ.

PLoS One. 2018 Dec 19;13(12):e0200863. doi: 10.1371/journal.pone.0200863. eCollection 2018.


Cell-cycle control of cell polarity in yeast.

Moran KD, Kang H, Araujo AV, Zyla TR, Saito K, Tsygankov D, Lew DJ.

J Cell Biol. 2019 Jan 7;218(1):171-189. doi: 10.1083/jcb.201806196. Epub 2018 Nov 20.


Mating in wild yeast: delayed interest in sex after spore germination.

McClure AW, Jacobs KC, Zyla TR, Lew DJ.

Mol Biol Cell. 2018 Oct 24:mbcE18080528. doi: 10.1091/mbc.E18-08-0528. [Epub ahead of print]


Temporal regulation of morphogenetic events in Saccharomyces cerevisiae.

Lai H, Chiou JG, Zhurikhina A, Zyla TR, Tsygankov D, Lew DJ.

Mol Biol Cell. 2018 Aug 15;29(17):2069-2083. doi: 10.1091/mbc.E18-03-0188. Epub 2018 Jun 21.


Parallel Actin-Independent Recycling Pathways Polarize Cdc42 in Budding Yeast.

Woods B, Lai H, Wu CF, Zyla TR, Savage NS, Lew DJ.

Curr Biol. 2016 Aug 22;26(16):2114-26. doi: 10.1016/j.cub.2016.06.047. Epub 2016 Jul 28.


Role of Polarized G Protein Signaling in Tracking Pheromone Gradients.

McClure AW, Minakova M, Dyer JM, Zyla TR, Elston TC, Lew DJ.

Dev Cell. 2015 Nov 23;35(4):471-82. doi: 10.1016/j.devcel.2015.10.024.


Role of competition between polarity sites in establishing a unique front.

Wu CF, Chiou JG, Minakova M, Woods B, Tsygankov D, Zyla TR, Savage NS, Elston TC, Lew DJ.

Elife. 2015 Nov 2;4. pii: e11611. doi: 10.7554/eLife.11611.


Polarity establishment requires localized activation of Cdc42.

Woods B, Kuo CC, Wu CF, Zyla TR, Lew DJ.

J Cell Biol. 2015 Oct 12;211(1):19-26. doi: 10.1083/jcb.201506108.


Inhibitory GEF phosphorylation provides negative feedback in the yeast polarity circuit.

Kuo CC, Savage NS, Chen H, Wu CF, Zyla TR, Lew DJ.

Curr Biol. 2014 Mar 31;24(7):753-9. doi: 10.1016/j.cub.2014.02.024. Epub 2014 Mar 13.


Tracking shallow chemical gradients by actin-driven wandering of the polarization site.

Dyer JM, Savage NS, Jin M, Zyla TR, Elston TC, Lew DJ.

Curr Biol. 2013 Jan 7;23(1):32-41. doi: 10.1016/j.cub.2012.11.014. Epub 2012 Nov 29.


Cdc42p regulation of the yeast formin Bni1p mediated by the effector Gic2p.

Chen H, Kuo CC, Kang H, Howell AS, Zyla TR, Jin M, Lew DJ.

Mol Biol Cell. 2012 Oct;23(19):3814-26. doi: 10.1091/mbc.E12-05-0400. Epub 2012 Aug 23.


Negative feedback enhances robustness in the yeast polarity establishment circuit.

Howell AS, Jin M, Wu CF, Zyla TR, Elston TC, Lew DJ.

Cell. 2012 Apr 13;149(2):322-33. doi: 10.1016/j.cell.2012.03.012.


Singularity in polarization: rewiring yeast cells to make two buds.

Howell AS, Savage NS, Johnson SA, Bose I, Wagner AW, Zyla TR, Nijhout HF, Reed MC, Goryachev AB, Lew DJ.

Cell. 2009 Nov 13;139(4):731-43. doi: 10.1016/j.cell.2009.10.024.


Molecular dissection of the checkpoint kinase Hsl1p.

Crutchley J, King KM, Keaton MA, Szkotnicki L, Orlando DA, Zyla TR, Bardes ES, Lew DJ.

Mol Biol Cell. 2009 Apr;20(7):1926-36. doi: 10.1091/mbc.E08-08-0848. Epub 2009 Feb 11.


Symmetry-breaking polarization driven by a Cdc42p GEF-PAK complex.

Kozubowski L, Saito K, Johnson JM, Howell AS, Zyla TR, Lew DJ.

Curr Biol. 2008 Nov 25;18(22):1719-26. doi: 10.1016/j.cub.2008.09.060. Epub 2008 Nov 13.


The checkpoint kinase Hsl1p is activated by Elm1p-dependent phosphorylation.

Szkotnicki L, Crutchley JM, Zyla TR, Bardes ES, Lew DJ.

Mol Biol Cell. 2008 Nov;19(11):4675-86. doi: 10.1091/mbc.E08-06-0663. Epub 2008 Sep 3.


Nucleocytoplasmic trafficking of G2/M regulators in yeast.

Keaton MA, Szkotnicki L, Marquitz AR, Harrison J, Zyla TR, Lew DJ.

Mol Biol Cell. 2008 Sep;19(9):4006-18. doi: 10.1091/mbc.E08-03-0286. Epub 2008 Jun 18.


Differential susceptibility of yeast S and M phase CDK complexes to inhibitory tyrosine phosphorylation.

Keaton MA, Bardes ES, Marquitz AR, Freel CD, Zyla TR, Rudolph J, Lew DJ.

Curr Biol. 2007 Jul 17;17(14):1181-9. Epub 2007 Jul 5.


Interplay between septin organization, cell cycle and cell shape in yeast.

Gladfelter AS, Kozubowski L, Zyla TR, Lew DJ.

J Cell Sci. 2005 Apr 15;118(Pt 8):1617-28. Epub 2005 Mar 22.


Genetic interactions among regulators of septin organization.

Gladfelter AS, Zyla TR, Lew DJ.

Eukaryot Cell. 2004 Aug;3(4):847-54.


Stress-specific activation mechanisms for the "cell integrity" MAPK pathway.

Harrison JC, Zyla TR, Bardes ES, Lew DJ.

J Biol Chem. 2004 Jan 23;279(4):2616-22. Epub 2003 Nov 10.


A monitor for bud emergence in the yeast morphogenesis checkpoint.

Theesfeld CL, Zyla TR, Bardes EG, Lew DJ.

Mol Biol Cell. 2003 Aug;14(8):3280-91. Epub 2003 May 3.


The Rho-GAP Bem2p plays a GAP-independent role in the morphogenesis checkpoint.

Marquitz AR, Harrison JC, Bose I, Zyla TR, McMillan JN, Lew DJ.

EMBO J. 2002 Aug 1;21(15):4012-25.


Septin ring assembly involves cycles of GTP loading and hydrolysis by Cdc42p.

Gladfelter AS, Bose I, Zyla TR, Bardes ES, Lew DJ.

J Cell Biol. 2002 Jan 21;156(2):315-26. Epub 2002 Jan 21.


Isolation and characterization of effector-loop mutants of CDC42 in yeast.

Gladfelter AS, Moskow JJ, Zyla TR, Lew DJ.

Mol Biol Cell. 2001 May;12(5):1239-55.


Assembly of scaffold-mediated complexes containing Cdc42p, the exchange factor Cdc24p, and the effector Cla4p required for cell cycle-regulated phosphorylation of Cdc24p.

Bose I, Irazoqui JE, Moskow JJ, Bardes ES, Zyla TR, Lew DJ.

J Biol Chem. 2001 Mar 9;276(10):7176-86. Epub 2000 Dec 11.

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