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Items: 1 to 50 of 133

1.

Resistance to Plant-Parasitic Nematodes in Chickpea: Current Status and Future Perspectives.

Zwart RS, Thudi M, Channale S, Manchikatla PK, Varshney RK, Thompson JP.

Front Plant Sci. 2019 Jul 24;10:966. doi: 10.3389/fpls.2019.00966. eCollection 2019.

2.

Arrhythmogenic Right Ventricular Cardiomyopathy-Associated Desmosomal Variants Are Rarely De Novo.

van Lint FHM, Murray B, Tichnell C, Zwart R, Amat N, Lekanne Deprez RH, Dittmann S, Stallmeyer B, Calkins H, van der Smagt JJ, van den Wijngaard A, Dooijes D, van der Zwaag PA, Schulze-Bahr E, Judge DP, Jongbloed JDH, van Tintelen JP, James CA.

Circ Genom Precis Med. 2019 Aug;12(8):e002467. doi: 10.1161/CIRCGEN.119.002467. Epub 2019 Aug 6.

PMID:
31386562
3.

Modulation of TARP γ8-Containing AMPA Receptors as a Novel Therapeutic Approach for Chronic Pain.

Knopp KL, Simmons RMA, Guo W, Adams BL, Gardinier KM, Gernert DL, Ornstein PL, Porter W, Reel J, Ding C, Wang H, Qian Y, Burris KD, Need A, Barth V, Swanson S, Catlow J, Witkin JM, Zwart R, Sher E, Choong KC, Wall TM, Schober D, Felder CC, Kato AS, Bredt DS, Nisenbaum ES.

J Pharmacol Exp Ther. 2019 Jun;369(3):345-363. doi: 10.1124/jpet.118.250126. Epub 2019 Mar 25.

PMID:
30910921
4.

Shared Decision-Making in Kidney Patients: Involvement in Decisions Regarding the Quality of Deceased Donor Kidneys.

van Hoogdalem LE, Hoitsma A, Timman R, van der Zwart R, Körnmann J, van Rijssel T, Busschbach JJV, Ismail SY.

Transplant Proc. 2018 Dec;50(10):3152-3159. doi: 10.1016/j.transproceed.2018.06.045. Epub 2018 Jun 30.

PMID:
30577181
5.

Microtransplantation of human brain receptors into oocytes to tackle key questions in drug discovery.

Zwart R, Mazzo F, Sher E.

Drug Discov Today. 2019 Feb;24(2):533-543. doi: 10.1016/j.drudis.2018.10.015. Epub 2018 Nov 3. Review.

PMID:
30395928
6.

Identification and pharmacological profile of SPP1, a potent, functionally selective and brain penetrant agonist at muscarinic M1 receptors.

Broad LM, Sanger HE, Mogg AJ, Colvin EM, Zwart R, Evans DA, Pasqui F, Sher E, Wishart GN, Barth VN, Felder CC, Goldsmith PJ.

Br J Pharmacol. 2019 Jan;176(1):110-126. doi: 10.1111/bph.14510. Epub 2018 Nov 16.

PMID:
30276808
7.

Methyl Perillate as a Highly Functionalized Natural Starting Material for Terephthalic Acid.

Jongedijk E, van der Klis F, de Zwart R, van Es DS, Beekwilder J.

ChemistryOpen. 2018 Feb 8;7(2):201-203. doi: 10.1002/open.201700178. eCollection 2018 Feb.

8.

Proteomic analysis of postsynaptic proteins in regions of the human neocortex.

Roy M, Sorokina O, Skene N, Simonnet C, Mazzo F, Zwart R, Sher E, Smith C, Armstrong JD, Grant SGN.

Nat Neurosci. 2018 Jan;21(1):130-138. doi: 10.1038/s41593-017-0025-9. Epub 2017 Dec 4.

9.

Oxotremorine-M potentiates NMDA receptors by muscarinic receptor dependent and independent mechanisms.

Zwart R, Reed H, Sher E.

Biochem Biophys Res Commun. 2018 Jan 1;495(1):481-486. doi: 10.1016/j.bbrc.2017.11.036. Epub 2017 Nov 7.

PMID:
29127015
10.

Insulin deficiency results in reversible protein kinase A activation and tau phosphorylation.

van der Harg JM, Eggels L, Bangel FN, Ruigrok SR, Zwart R, Hoozemans JJM, la Fleur SE, Scheper W.

Neurobiol Dis. 2017 Jul;103:163-173. doi: 10.1016/j.nbd.2017.04.005. Epub 2017 Apr 8.

PMID:
28400135
11.

Forebrain-selective AMPA-receptor antagonism guided by TARP γ-8 as an antiepileptic mechanism.

Kato AS, Burris KD, Gardinier KM, Gernert DL, Porter WJ, Reel J, Ding C, Tu Y, Schober DA, Lee MR, Heinz BA, Fitch TE, Gleason SD, Catlow JT, Yu H, Fitzjohn SM, Pasqui F, Wang H, Qian Y, Sher E, Zwart R, Wafford KA, Rasmussen K, Ornstein PL, Isaac JT, Nisenbaum ES, Bredt DS, Witkin JM.

Nat Med. 2016 Dec;22(12):1496-1501. doi: 10.1038/nm.4221. Epub 2016 Nov 7.

PMID:
27820603
12.

A novel muscarinic receptor-independent mechanism of KCNQ2/3 potassium channel blockade by Oxotremorine-M.

Zwart R, Reed H, Clarke S, Sher E.

Eur J Pharmacol. 2016 Nov 15;791:221-228. doi: 10.1016/j.ejphar.2016.08.037. Epub 2016 Aug 31.

PMID:
27590358
13.

Transition from paediatric to adult care of adolescent patients with congenital heart disease: a pathway to optimal care.

Strijbosch AM, Zwart R, Blom NA, Bouma BJ, Groenink M, Boekholdt SM, de Winter R, Mulder BJ, Backx AP.

Neth Heart J. 2016 Nov;24(11):682-690.

14.

Mobile health in adults with congenital heart disease: current use and future needs.

Schuuring MJ, Backx AP, Zwart R, Veelenturf AH, Robbers-Visser D, Groenink M, Abu-Hanna A, Bruining N, Schijven MP, Mulder BJ, Bouma BJ.

Neth Heart J. 2016 Nov;24(11):647-652.

15.

Reconstitution of synaptic Ion channels from rodent and human brain in Xenopus oocytes: a biochemical and electrophysiological characterization.

Mazzo F, Zwart R, Serratto GM, Gardinier KM, Porter W, Reel J, Maraula G, Sher E.

J Neurochem. 2016 Aug;138(3):384-96. doi: 10.1111/jnc.13675. Epub 2016 Jun 13.

16.

Electrophysiological characterization of human and mouse sodium-dependent citrate transporters (NaCT/SLC13A5) reveal species differences with respect to substrate sensitivity and cation dependence.

Zwart R, Peeva PM, Rong JX, Sher E.

J Pharmacol Exp Ther. 2015 Nov;355(2):247-54. doi: 10.1124/jpet.115.226902. Epub 2015 Aug 31.

PMID:
26324167
17.

α7 and β2 Nicotinic Acetylcholine Receptor Subunits Form Heteromeric Receptor Complexes that Are Expressed in the Human Cortex and Display Distinct Pharmacological Properties.

Thomsen MS, Zwart R, Ursu D, Jensen MM, Pinborg LH, Gilmour G, Wu J, Sher E, Mikkelsen JD.

PLoS One. 2015 Jun 18;10(6):e0130572. doi: 10.1371/journal.pone.0130572. eCollection 2015.

18.

BRI2 ectodomain affects Aβ42 fibrillation and tau truncation in human neuroblastoma cells.

Del Campo M, Oliveira CR, Scheper W, Zwart R, Korth C, Müller-Schiffmann A, Kostallas G, Biverstal H, Presto J, Johansson J, Hoozemans JJ, Pereira CF, Teunissen CE.

Cell Mol Life Sci. 2015 Apr;72(8):1599-611. doi: 10.1007/s00018-014-1769-y. Epub 2014 Oct 22.

PMID:
25336154
19.

The unfolded protein response mediates reversible tau phosphorylation induced by metabolic stress.

van der Harg JM, Nölle A, Zwart R, Boerema AS, van Haastert ES, Strijkstra AM, Hoozemans JJ, Scheper W.

Cell Death Dis. 2014 Aug 28;5:e1393. doi: 10.1038/cddis.2014.354.

20.

Perampanel, an antagonist of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors, for the treatment of epilepsy: studies in human epileptic brain and nonepileptic brain and in rodent models.

Zwart R, Sher E, Ping X, Jin X, Sims JR Jr, Chappell AS, Gleason SD, Hahn PJ, Gardinier K, Gernert DL, Hobbs J, Smith JL, Valli SN, Witkin JM.

J Pharmacol Exp Ther. 2014 Oct;351(1):124-33. doi: 10.1124/jpet.114.212779. Epub 2014 Jul 15.

PMID:
25027316
21.

Unique pharmacology of heteromeric α7β2 nicotinic acetylcholine receptors expressed in Xenopus laevis oocytes.

Zwart R, Strotton M, Ching J, Astles PC, Sher E.

Eur J Pharmacol. 2014 Mar 5;726:77-86.

PMID:
24485886
22.

Liposomes bi-functionalized with phosphatidic acid and an ApoE-derived peptide affect Aβ aggregation features and cross the blood-brain-barrier: implications for therapy of Alzheimer disease.

Bana L, Minniti S, Salvati E, Sesana S, Zambelli V, Cagnotto A, Orlando A, Cazzaniga E, Zwart R, Scheper W, Masserini M, Re F.

Nanomedicine. 2014 Oct;10(7):1583-90. doi: 10.1016/j.nano.2013.12.001. Epub 2013 Dec 10.

PMID:
24333591
23.

Ubiquilin 2 is not associated with tau pathology.

Nölle A, van Haastert ES, Zwart R, Hoozemans JJ, Scheper W.

PLoS One. 2013 Sep 26;8(9):e76598. doi: 10.1371/journal.pone.0076598. eCollection 2013.

24.

Inhibition of endoplasmic reticulum associated degradation reduces endoplasmic reticulum stress and alters lysosomal morphology and distribution.

Elfrink HL, Zwart R, Baas F, Scheper W.

Mol Cells. 2013 Apr;35(4):291-7. doi: 10.1007/s10059-013-2286-9. Epub 2013 Mar 18.

25.

Peri-operative care in adults with congenital heart disease: room for improvement in after care.

Schoormans D, Smets EM, Zwart R, Sprangers MA, Veelenturg TH, de Mol BA, Hazekamp MG, Koolbergen DR, Sojak V, Bouma BJ, Groenink M, Boekholdt MS, Backx AP, Mulder BJ.

Cardiol Young. 2013 Aug;23(4):540-5. doi: 10.1017/S1047951112001254. Epub 2012 Oct 2.

PMID:
23025898
26.

Disturbed Ca2+ homeostasis increases glutaminyl cyclase expression; connecting two early pathogenic events in Alzheimer's disease in vitro.

De Kimpe L, Bennis A, Zwart R, van Haastert ES, Hoozemans JJ, Scheper W.

PLoS One. 2012;7(9):e44674. doi: 10.1371/journal.pone.0044674. Epub 2012 Sep 7.

27.

Intracellular accumulation of aggregated pyroglutamate amyloid beta: convergence of aging and Aβ pathology at the lysosome.

De Kimpe L, van Haastert ES, Kaminari A, Zwart R, Rutjes H, Hoozemans JJ, Scheper W.

Age (Dordr). 2013 Jun;35(3):673-87. doi: 10.1007/s11357-012-9403-0. Epub 2012 Apr 4.

28.

Rab6 is a modulator of the unfolded protein response: implications for Alzheimer's disease.

Elfrink HL, Zwart R, Cavanillas ML, Schindler AJ, Baas F, Scheper W.

J Alzheimers Dis. 2012;28(4):917-29. doi: 10.3233/JAD-2011-110971.

PMID:
22124028
29.

Partial agonists for α4β2 nicotinic receptors stimulate dopaminergic neuron firing with relatively enhanced maximal effects.

Chen Y, Broad LM, Phillips KG, Zwart R.

Br J Pharmacol. 2012 Feb;165(4):1006-16. doi: 10.1111/j.1476-5381.2011.01628.x.

30.

Agonist activation of alpha7 nicotinic acetylcholine receptors via an allosteric transmembrane site.

Gill JK, Savolainen M, Young GT, Zwart R, Sher E, Millar NS.

Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5867-72. doi: 10.1073/pnas.1017975108. Epub 2011 Mar 21.

31.

Lingual nerve injury following the use of an i-gel laryngeal mask.

Renes SH, Zwart R, Scheffer GJ, Renes S.

Anaesthesia. 2011 Mar;66(3):226-7. doi: 10.1111/j.1365-2044.2011.06636.x. No abstract available.

32.

Endoplasmic reticulum stress activates autophagy but not the proteasome in neuronal cells: implications for Alzheimer's disease.

Nijholt DA, de Graaf TR, van Haastert ES, Oliveira AO, Berkers CR, Zwart R, Ovaa H, Baas F, Hoozemans JJ, Scheper W.

Cell Death Differ. 2011 Jun;18(6):1071-81. doi: 10.1038/cdd.2010.176. Epub 2011 Jan 21.

33.

The subtype-selective nicotinic acetylcholine receptor positive allosteric potentiator 2087101 differentially facilitates neurotransmission in the brain.

de Filippi G, Mogg AJ, Phillips KG, Zwart R, Sher E, Chen Y.

Eur J Pharmacol. 2010 Sep 25;643(2-3):218-24. doi: 10.1016/j.ejphar.2010.06.064. Epub 2010 Jul 15.

PMID:
20624387
34.

Increased Abeta1-42 production sensitizes neuroblastoma cells for ER stress toxicity.

Chafekar SM, Zwart R, Veerhuis R, Vanderstichele H, Baas F, Scheper W.

Curr Alzheimer Res. 2008 Oct;5(5):469-74.

PMID:
18855588
35.

Potentiation of alpha7 nicotinic acetylcholine receptors via an allosteric transmembrane site.

Young GT, Zwart R, Walker AS, Sher E, Millar NS.

Proc Natl Acad Sci U S A. 2008 Sep 23;105(38):14686-91. doi: 10.1073/pnas.0804372105. Epub 2008 Sep 12.

36.
37.

Evaluation of genetic diversity of Fusarium head blight resistance in European winter wheat.

Zwart RS, Muylle H, Van Bockstaele E, Roldán-Ruiz I.

Theor Appl Genet. 2008 Sep;117(5):813-28. doi: 10.1007/s00122-008-0822-3. Epub 2008 Jun 28.

PMID:
18587558
38.

Sazetidine-A is a potent and selective agonist at native and recombinant alpha 4 beta 2 nicotinic acetylcholine receptors.

Zwart R, Carbone AL, Moroni M, Bermudez I, Mogg AJ, Folly EA, Broad LM, Williams AC, Zhang D, Ding C, Heinz BA, Sher E.

Mol Pharmacol. 2008 Jun;73(6):1838-43. doi: 10.1124/mol.108.045104. Epub 2008 Mar 26.

PMID:
18367540
39.

Pathogenesis of Herpesvirus anguillae (HVA) in juvenile European eel Anguilla anguilla after infection by bath immersion.

Hangalapura BN, Zwart R, Engelsma MY, Haenen OL.

Dis Aquat Organ. 2007 Oct 31;78(1):13-22.

40.

Abeta 1-42 induces mild endoplasmic reticulum stress in an aggregation state-dependent manner.

Chafekar SM, Hoozemans JJ, Zwart R, Baas F, Scheper W.

Antioxid Redox Signal. 2007 Dec;9(12):2245-54.

PMID:
17979527
41.

Is there an effect of prenatal breech position on locomotion at 2.5 years?

Fong B, Ledebt A, Zwart R, De Vries JI, Savelsbergh GJ.

Early Hum Dev. 2008 Apr;84(4):211-6. Epub 2007 Jun 15.

PMID:
17573208
42.

Species selectivity of a nicotinic acetylcholine receptor agonist is conferred by two adjacent extracellular beta4 amino acids that are implicated in the coupling of binding to channel gating.

Young GT, Broad LM, Zwart R, Astles PC, Bodkin M, Sher E, Millar NS.

Mol Pharmacol. 2007 Feb;71(2):389-97. Epub 2006 Oct 25.

PMID:
17065235
43.

Pin1 levels are downregulated during ER stress in human neuroblastoma cells.

Kap YS, Hoozemans JJ, Bodewes AJ, Zwart R, Meijer OC, Baas F, Scheper W.

Neurogenetics. 2007 Jan;8(1):21-7. Epub 2006 Sep 14.

PMID:
16972081
44.

Chaperone protein 14-3-3 and protein kinase A increase the relative abundance of low agonist sensitivity human alpha 4 beta 2 nicotinic acetylcholine receptors in Xenopus oocytes.

Exley R, Moroni M, Sasdelli F, Houlihan LM, Lukas RJ, Sher E, Zwart R, Bermudez I.

J Neurochem. 2006 Aug;98(3):876-85. Epub 2006 Jun 19.

45.

Identification and pharmacological profile of a new class of selective nicotinic acetylcholine receptor potentiators.

Broad LM, Zwart R, Pearson KH, Lee M, Wallace L, McPhie GI, Emkey R, Hollinshead SP, Dell CP, Baker SR, Sher E.

J Pharmacol Exp Ther. 2006 Sep;318(3):1108-17. Epub 2006 May 31.

PMID:
16738207
46.

alpha4beta2 nicotinic receptors with high and low acetylcholine sensitivity: pharmacology, stoichiometry, and sensitivity to long-term exposure to nicotine.

Moroni M, Zwart R, Sher E, Cassels BK, Bermudez I.

Mol Pharmacol. 2006 Aug;70(2):755-68. Epub 2006 May 23.

PMID:
16720757
47.

5-I A-85380 and TC-2559 differentially activate heterologously expressed alpha4beta2 nicotinic receptors.

Zwart R, Broad LM, Xi Q, Lee M, Moroni M, Bermudez I, Sher E.

Eur J Pharmacol. 2006 Jun 6;539(1-2):10-7. Epub 2006 Apr 5.

PMID:
16674940
48.

Cholinergic drugs potentiate human nicotinic alpha4beta2 acetylcholine receptors by a competitive mechanism.

Smulders CJ, Zwart R, Bermudez I, van Kleef RG, Groot-Kormelink PJ, Vijverberg HP.

Eur J Pharmacol. 2005 Feb 21;509(2-3):97-108.

PMID:
15733544
49.

Alternative splicing in the N-terminus of Alzheimer's presenilin 1.

Scheper W, Zwart R, Baas F.

Neurogenetics. 2004 Dec;5(4):223-7. Epub 2004 Oct 5.

PMID:
15480879
50.

Stable expression and characterisation of a human alpha 7 nicotinic subunit chimera: a tool for functional high-throughput screening.

Craig PJ, Bose S, Zwart R, Beattie RE, Folly EA, Johnson LR, Bell E, Evans NM, Benedetti G, Pearson KH, McPhie GI, Volsen SG, Millar NS, Sher E, Broad LM.

Eur J Pharmacol. 2004 Oct 11;502(1-2):31-40.

PMID:
15464087

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