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Items: 4

1.

The lipoprotein receptor LRP1 modulates sphingosine-1-phosphate signaling and is essential for vascular development.

Nakajima C, Haffner P, Goerke SM, Zurhove K, Adelmann G, Frotscher M, Herz J, Bock HH, May P.

Development. 2014 Dec;141(23):4513-25. doi: 10.1242/dev.109124. Epub 2014 Nov 5.

2.

Gamma-secretase limits the inflammatory response through the processing of LRP1.

Zurhove K, Nakajima C, Herz J, Bock HH, May P.

Sci Signal. 2008 Nov 25;1(47):ra15. doi: 10.1126/scisignal.1164263.

3.

LRP1 controls intracellular cholesterol storage and fatty acid synthesis through modulation of Wnt signaling.

Terrand J, Bruban V, Zhou L, Gong W, El Asmar Z, May P, Zurhove K, Haffner P, Philippe C, Woldt E, Matz RL, Gracia C, Metzger D, Auwerx J, Herz J, Boucher P.

J Biol Chem. 2009 Jan 2;284(1):381-8. doi: 10.1074/jbc.M806538200. Epub 2008 Nov 6.

4.

Neuronal LRP1 functionally associates with postsynaptic proteins and is required for normal motor function in mice.

May P, Rohlmann A, Bock HH, Zurhove K, Marth JD, Schomburg ED, Noebels JL, Beffert U, Sweatt JD, Weeber EJ, Herz J.

Mol Cell Biol. 2004 Oct;24(20):8872-83.

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