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Items: 1 to 50 of 192

1.

Early uneven ear input induces long-lasting differences in left-right motor function.

Antoine MW, Zhu X, Dieterich M, Brandt T, Vijayakumar S, McKeehan N, Arezzo JC, Zukin RS, Borkholder DA, Jones SM, Frisina RD, Hébert JM.

PLoS Biol. 2018 Mar 13;16(3):e2002988. doi: 10.1371/journal.pbio.2002988. eCollection 2018 Mar.

2.

REST, a master transcriptional regulator in neurodegenerative disease.

Hwang JY, Zukin RS.

Curr Opin Neurobiol. 2018 Feb;48:193-200. doi: 10.1016/j.conb.2017.12.008. Epub 2018 Jan 30. Review.

3.

Aberrant Rac1-cofilin signaling mediates defects in dendritic spines, synaptic function, and sensory perception in fragile X syndrome.

Pyronneau A, He Q, Hwang JY, Porch M, Contractor A, Zukin RS.

Sci Signal. 2017 Nov 7;10(504). pii: eaan0852. doi: 10.1126/scisignal.aan0852.

4.

The emerging field of epigenetics in neurodegeneration and neuroprotection.

Hwang JY, Aromolaran KA, Zukin RS.

Nat Rev Neurosci. 2017 May 18;18(6):347-361. doi: 10.1038/nrn.2017.46. Review.

PMID:
28515491
5.

Global ischemia induces lysosomal-mediated degradation of mTOR and activation of autophagy in hippocampal neurons destined to die.

Hwang JY, Gertner M, Pontarelli F, Court-Vazquez B, Bennett MV, Ofengeim D, Zukin RS.

Cell Death Differ. 2017 Feb;24(2):317-329. doi: 10.1038/cdd.2016.140. Epub 2016 Dec 9.

6.

Elevated ERK/p90 ribosomal S6 kinase activity underlies audiogenic seizure susceptibility in fragile X mice.

Sawicka K, Pyronneau A, Chao M, Bennett MV, Zukin RS.

Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6290-E6297. Epub 2016 Sep 23.

7.

Multiple Drug Treatments That Increase cAMP Signaling Restore Long-Term Memory and Aberrant Signaling in Fragile X Syndrome Models.

Choi CH, Schoenfeld BP, Bell AJ, Hinchey J, Rosenfelt C, Gertner MJ, Campbell SR, Emerson D, Hinchey P, Kollaros M, Ferrick NJ, Chambers DB, Langer S, Sust S, Malik A, Terlizzi AM, Liebelt DA, Ferreiro D, Sharma A, Koenigsberg E, Choi RJ, Louneva N, Arnold SE, Featherstone RE, Siegel SJ, Zukin RS, McDonald TV, Bolduc FV, Jongens TA, McBride SM.

Front Behav Neurosci. 2016 Jun 30;10:136. doi: 10.3389/fnbeh.2016.00136. eCollection 2016.

8.

hERG 1a LQT2 C-terminus truncation mutants display hERG 1b-dependent dominant negative mechanisms.

Puckerin A, Aromolaran KA, Chang DD, Zukin RS, Colecraft HM, Boutjdir M, Aromolaran AS.

Heart Rhythm. 2016 May;13(5):1121-30. doi: 10.1016/j.hrthm.2016.01.012. Epub 2016 Jan 13.

PMID:
26775140
9.

Dysregulation of Mammalian Target of Rapamycin Signaling in Mouse Models of Autism.

Huber KM, Klann E, Costa-Mattioli M, Zukin RS.

J Neurosci. 2015 Oct 14;35(41):13836-42. doi: 10.1523/JNEUROSCI.2656-15.2015. Review.

10.

Schizophrenia: Evidence implicating hippocampal GluN2B protein and REST epigenetics in psychosis pathophysiology.

Tamminga CA, Zukin RS.

Neuroscience. 2015 Nov 19;309:233-42. doi: 10.1016/j.neuroscience.2015.07.038. Epub 2015 Jul 23. Review.

11.

PDE-4 inhibition rescues aberrant synaptic plasticity in Drosophila and mouse models of fragile X syndrome.

Choi CH, Schoenfeld BP, Weisz ED, Bell AJ, Chambers DB, Hinchey J, Choi RJ, Hinchey P, Kollaros M, Gertner MJ, Ferrick NJ, Terlizzi AM, Yohn N, Koenigsberg E, Liebelt DA, Zukin RS, Woo NH, Tranfaglia MR, Louneva N, Arnold SE, Siegel SJ, Bolduc FV, McDonald TV, Jongens TA, McBride SM.

J Neurosci. 2015 Jan 7;35(1):396-408. doi: 10.1523/JNEUROSCI.1356-12.2015.

12.

Estradiol pretreatment ameliorates impaired synaptic plasticity at synapses of insulted CA1 neurons after transient global ischemia.

Takeuchi K, Yang Y, Takayasu Y, Gertner M, Hwang JY, Aromolaran K, Bennett MV, Zukin RS.

Brain Res. 2015 Sep 24;1621:222-30. doi: 10.1016/j.brainres.2014.11.016. Epub 2014 Nov 22.

13.

The gene silencing transcription factor REST represses miR-132 expression in hippocampal neurons destined to die.

Hwang JY, Kaneko N, Noh KM, Pontarelli F, Zukin RS.

J Mol Biol. 2014 Oct 9;426(20):3454-66. doi: 10.1016/j.jmb.2014.07.032. Epub 2014 Aug 6.

14.

Casein kinase 1 suppresses activation of REST in insulted hippocampal neurons and halts ischemia-induced neuronal death.

Kaneko N, Hwang JY, Gertner M, Pontarelli F, Zukin RS.

J Neurosci. 2014 Apr 23;34(17):6030-9. doi: 10.1523/JNEUROSCI.4045-13.2014.

15.

Phosphorylation of Ser1166 on GluN2B by PKA is critical to synaptic NMDA receptor function and Ca2+ signaling in spines.

Murphy JA, Stein IS, Lau CG, Peixoto RT, Aman TK, Kaneko N, Aromolaran K, Saulnier JL, Popescu GK, Sabatini BL, Hell JW, Zukin RS.

J Neurosci. 2014 Jan 15;34(3):869-79. doi: 10.1523/JNEUROSCI.4538-13.2014.

16.

Survivin Is a transcriptional target of STAT3 critical to estradiol neuroprotection in global ischemia.

Sehara Y, Sawicka K, Hwang JY, Latuszek-Barrantes A, Etgen AM, Zukin RS.

J Neurosci. 2013 Jul 24;33(30):12364-74. doi: 10.1523/JNEUROSCI.1852-13.2013.

17.

Dysregulation of synaptic plasticity precedes appearance of morphological defects in a Pten conditional knockout mouse model of autism.

Takeuchi K, Gertner MJ, Zhou J, Parada LF, Bennett MV, Zukin RS.

Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):4738-43. doi: 10.1073/pnas.1222803110. Epub 2013 Mar 4.

18.

Gintonin, a ginseng-derived novel ingredient, evokes long-term potentiation through N-methyl-D-aspartic acid receptor activation: involvement of LPA receptors.

Shin TJ, Kim HJ, Kwon BJ, Choi SH, Kim HB, Hwang SH, Lee BH, Lee SM, Zukin RS, Park JH, Kim HC, Rhim H, Lee JH, Nah SY.

Mol Cells. 2012 Dec;34(6):563-72. doi: 10.1007/s10059-012-0254-4. Epub 2012 Nov 15.

19.

Mouse Transient Global Ischemia Two-Vessel Occlusion Model.

Pontarelli F, Ofengeim D, Zukin RS, Jonas EA.

Bio Protoc. 2012 Sep 20;2(18). pii: e262.

20.

REST-dependent epigenetic remodeling promotes the developmental switch in synaptic NMDA receptors.

Rodenas-Ruano A, Chávez AE, Cossio MJ, Castillo PE, Zukin RS.

Nat Neurosci. 2012 Oct;15(10):1382-90. doi: 10.1038/nn.3214. Epub 2012 Sep 9.

21.

Epigenetic mechanisms in stroke and epilepsy.

Hwang JY, Aromolaran KA, Zukin RS.

Neuropsychopharmacology. 2013 Jan;38(1):167-82. doi: 10.1038/npp.2012.134. Epub 2012 Aug 15. Review.

22.

Effects of global ischemia and estradiol pretreatment on phosphorylation of Akt, CREB and STAT3 in hippocampal CA1 of young and middle-aged female rats.

De Butte-Smith M, Zukin RS, Etgen AM.

Brain Res. 2012 Aug 30;1471:118-28. doi: 10.1016/j.brainres.2012.06.036. Epub 2012 Jul 4.

23.

Bidirectional control of mRNA translation and synaptic plasticity by the cytoplasmic polyadenylation complex.

Udagawa T, Swanger SA, Takeuchi K, Kim JH, Nalavadi V, Shin J, Lorenz LJ, Zukin RS, Bassell GJ, Richter JD.

Mol Cell. 2012 Jul 27;47(2):253-66. doi: 10.1016/j.molcel.2012.05.016. Epub 2012 Jun 21.

24.

Estradiol attenuates ischemia-induced death of hippocampal neurons and enhances synaptic transmission in aged, long-term hormone-deprived female rats.

Inagaki T, Kaneko N, Zukin RS, Castillo PE, Etgen AM.

PLoS One. 2012;7(6):e38018. doi: 10.1371/journal.pone.0038018. Epub 2012 Jun 4.

25.

Effects of protopanaxatriol-ginsenoside metabolites on rat N-methyl-d-aspartic Acid receptor-mediated ion currents.

Shin TJ, Hwang SH, Choi SH, Lee BH, Kang J, Kim HJ, Zukin RS, Rhim H, Nah SY.

Korean J Physiol Pharmacol. 2012 Apr;16(2):113-8. doi: 10.4196/kjpp.2012.16.2.113. Epub 2012 Apr 24.

26.

Repressor element-1 silencing transcription factor (REST)-dependent epigenetic remodeling is critical to ischemia-induced neuronal death.

Noh KM, Hwang JY, Follenzi A, Athanasiadou R, Miyawaki T, Greally JM, Bennett MV, Zukin RS.

Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):E962-71. doi: 10.1073/pnas.1121568109. Epub 2012 Feb 27.

27.

N-terminally cleaved Bcl-xL mediates ischemia-induced neuronal death.

Ofengeim D, Chen YB, Miyawaki T, Li H, Sacchetti S, Flannery RJ, Alavian KN, Pontarelli F, Roelofs BA, Hickman JA, Hardwick JM, Zukin RS, Jonas EA.

Nat Neurosci. 2012 Feb 26;15(4):574-80. doi: 10.1038/nn.3054.

28.

Altered mTOR signaling and enhanced CYFIP2 expression levels in subjects with fragile X syndrome.

Hoeffer CA, Sanchez E, Hagerman RJ, Mu Y, Nguyen DV, Wong H, Whelan AM, Zukin RS, Klann E, Tassone F.

Genes Brain Behav. 2012 Apr;11(3):332-41. doi: 10.1111/j.1601-183X.2012.00768.x. Epub 2012 Feb 15.

29.

Dysregulation of mTOR signaling in neuropsychiatric disorders: therapeutic implications.

Sawicka K, Zukin RS.

Neuropsychopharmacology. 2012 Jan;37(1):305-6. doi: 10.1038/npp.2011.210. No abstract available.

30.

A silent synapse-based mechanism for cocaine-induced locomotor sensitization.

Brown TE, Lee BR, Mu P, Ferguson D, Dietz D, Ohnishi YN, Lin Y, Suska A, Ishikawa M, Huang YH, Shen H, Kalivas PW, Sorg BA, Zukin RS, Nestler EJ, Dong Y, Schlüter OM.

J Neurosci. 2011 Jun 1;31(22):8163-74. doi: 10.1523/JNEUROSCI.0016-11.2011.

31.

β-Catenin-dependent FGF signaling sustains cell survival in the anterior embryonic head by countering Smad4.

Paek H, Hwang JY, Zukin RS, Hébert JM.

Dev Cell. 2011 May 17;20(5):689-99. doi: 10.1016/j.devcel.2011.04.010.

32.

EphB controls NMDA receptor function and synaptic targeting in a subunit-specific manner.

Nolt MJ, Lin Y, Hruska M, Murphy J, Sheffler-Colins SI, Kayser MS, Passer J, Bennett MV, Zukin RS, Dalva MB.

J Neurosci. 2011 Apr 6;31(14):5353-64. doi: 10.1523/JNEUROSCI.0282-11.2011.

33.

Serotonin mediates cross-modal reorganization of cortical circuits.

Jitsuki S, Takemoto K, Kawasaki T, Tada H, Takahashi A, Becamel C, Sano A, Yuzaki M, Zukin RS, Ziff EB, Kessels HW, Takahashi T.

Neuron. 2011 Feb 24;69(4):780-92. doi: 10.1016/j.neuron.2011.01.016.

34.

Neuroprotective actions of estradiol and novel estrogen analogs in ischemia: translational implications.

Etgen AM, Jover-Mengual T, Zukin RS.

Front Neuroendocrinol. 2011 Aug;32(3):336-52. doi: 10.1016/j.yfrne.2010.12.005. Epub 2010 Dec 14. Review.

35.

Caveolin-1 knockout mice exhibit impaired induction of mGluR-dependent long-term depression at CA3-CA1 synapses.

Takayasu Y, Takeuchi K, Kumari R, Bennett MV, Zukin RS, Francesconi A.

Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21778-83. doi: 10.1073/pnas.1015553107. Epub 2010 Nov 23.

36.

Pharmacological reversal of synaptic plasticity deficits in the mouse model of fragile X syndrome by group II mGluR antagonist or lithium treatment.

Choi CH, Schoenfeld BP, Bell AJ, Hinchey P, Kollaros M, Gertner MJ, Woo NH, Tranfaglia MR, Bear MF, Zukin RS, McDonald TV, Jongens TA, McBride SM.

Brain Res. 2011 Mar 22;1380:106-19. doi: 10.1016/j.brainres.2010.11.032. Epub 2010 Nov 12.

37.

Synapse-specific metaplasticity: to be silenced is not to silence 2B.

Philpot BD, Zukin RS.

Neuron. 2010 Jun 24;66(6):814-6. doi: 10.1016/j.neuron.2010.06.014.

38.

Eradicating the mediators of neuronal death with a fine-tooth comb.

Zukin RS.

Sci Signal. 2010 Jun 8;3(125):pe20. doi: 10.1126/scisignal.3125pe20.

39.

Spatially restricting gene expression by local translation at synapses.

Wang DO, Martin KC, Zukin RS.

Trends Neurosci. 2010 Apr;33(4):173-82. doi: 10.1016/j.tins.2010.01.005. Epub 2010 Mar 19. Review.

40.

Apurinic/apyrimidinic endonuclease APE1 is required for PACAP-induced neuroprotection against global cerebral ischemia.

Stetler RA, Gao Y, Zukin RS, Vosler PS, Zhang L, Zhang F, Cao G, Bennett MV, Chen J.

Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3204-9. doi: 10.1073/pnas.1000030107. Epub 2010 Feb 1.

41.

Acute estradiol protects CA1 neurons from ischemia-induced apoptotic cell death via the PI3K/Akt pathway.

Jover-Mengual T, Miyawaki T, Latuszek A, Alborch E, Zukin RS, Etgen AM.

Brain Res. 2010 Mar 19;1321:1-12. doi: 10.1016/j.brainres.2010.01.046. Epub 2010 Jan 28.

42.

Differences in NMDA receptor expression during human development determine the response of neurons to HIV-tat-mediated neurotoxicity.

Eugenin EA, King JE, Hazleton JE, Major EO, Bennett MV, Zukin RS, Berman JW.

Neurotox Res. 2011 Jan;19(1):138-48. doi: 10.1007/s12640-010-9150-x. Epub 2010 Jan 22.

43.

Dysregulation of mTOR signaling in fragile X syndrome.

Sharma A, Hoeffer CA, Takayasu Y, Miyawaki T, McBride SM, Klann E, Zukin RS.

J Neurosci. 2010 Jan 13;30(2):694-702. doi: 10.1523/JNEUROSCI.3696-09.2010.

44.

Acute administration of non-classical estrogen receptor agonists attenuates ischemia-induced hippocampal neuron loss in middle-aged female rats.

Lebesgue D, Traub M, De Butte-Smith M, Chen C, Zukin RS, Kelly MJ, Etgen AM.

PLoS One. 2010 Jan 8;5(1):e8642. doi: 10.1371/journal.pone.0008642.

45.

SNAP-25 is a target of protein kinase C phosphorylation critical to NMDA receptor trafficking.

Lau CG, Takayasu Y, Rodenas-Ruano A, Paternain AV, Lerma J, Bennett MV, Zukin RS.

J Neurosci. 2010 Jan 6;30(1):242-54. doi: 10.1523/JNEUROSCI.4933-08.2010.

46.

A single fear-inducing stimulus induces a transcription-dependent switch in synaptic AMPAR phenotype.

Liu Y, Formisano L, Savtchouk I, Takayasu Y, Szabó G, Zukin RS, Liu SJ.

Nat Neurosci. 2010 Feb;13(2):223-31. doi: 10.1038/nn.2474. Epub 2009 Dec 27.

47.

Regulation of NMDA receptor Ca2+ signalling and synaptic plasticity.

Lau CG, Takeuchi K, Rodenas-Ruano A, Takayasu Y, Murphy J, Bennett MV, Zukin RS.

Biochem Soc Trans. 2009 Dec;37(Pt 6):1369-74. doi: 10.1042/BST0371369.

48.

Oestradiol and insulin-like growth factor-1 reduce cell loss after global ischaemia in middle-aged female rats.

Traub ML, De Butte-Smith M, Zukin RS, Etgen AM.

J Neuroendocrinol. 2009 Dec;21(12):1038-44. doi: 10.1111/j.1365-2826.2009.01927.x. Epub 2009 Oct 14.

49.

Signals, synapses, and synthesis: how new proteins control plasticity.

Zukin RS, Richter JD, Bagni C.

Front Neural Circuits. 2009 Oct 7;3:14. doi: 10.3389/neuro.04.014.2009. eCollection 2009.

50.

In vivo cocaine experience generates silent synapses.

Huang YH, Lin Y, Mu P, Lee BR, Brown TE, Wayman G, Marie H, Liu W, Yan Z, Sorg BA, Schlüter OM, Zukin RS, Dong Y.

Neuron. 2009 Jul 16;63(1):40-7. doi: 10.1016/j.neuron.2009.06.007.

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