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Items: 42

1.

The Combined Effect of FGFR Inhibition and PD-1 Blockade Promotes Tumor-Intrinsic Induction of Antitumor Immunity.

Palakurthi S, Kuraguchi M, Zacharek SJ, Zudaire E, Huang W, Bonal DM, Liu J, Dhaneshwar A, DePeaux K, Gowaski MR, Bailey D, Regan SN, Ivanova E, Ferrante C, English JM, Khosla A, Beck AH, Rytlewski JA, Sanders C, Laquerre S, Bittinger MA, Kirschmeier PT, Packman K, Janne PA, Moy C, Wong KK, Verona RI, Lorenzi MV.

Cancer Immunol Res. 2019 Sep;7(9):1457-1471. doi: 10.1158/2326-6066.CIR-18-0595. Epub 2019 Jul 22.

PMID:
31331945
2.

Comprehensive genomic and immunological characterization of Chinese non-small cell lung cancer patients.

Zhang XC, Wang J, Shao GG, Wang Q, Qu X, Wang B, Moy C, Fan Y, Albertyn Z, Huang X, Zhang J, Qiu Y, Platero S, Lorenzi MV, Zudaire E, Yang J, Cheng Y, Xu L, Wu YL.

Nat Commun. 2019 Apr 16;10(1):1772. doi: 10.1038/s41467-019-09762-1.

3.

Tumor stroma-targeted antibody-drug conjugate triggers localized anticancer drug release.

Szot C, Saha S, Zhang XM, Zhu Z, Hilton MB, Morris K, Seaman S, Dunleavey JM, Hsu KS, Yu GJ, Morris H, Swing DA, Haines DC, Wang Y, Hwang J, Feng Y, Welsch D, DeCrescenzo G, Chaudhary A, Zudaire E, Dimitrov DS, St Croix B.

J Clin Invest. 2018 Jul 2;128(7):2927-2943. doi: 10.1172/JCI120481. Epub 2018 Jun 4.

4.

Eradication of Tumors through Simultaneous Ablation of CD276/B7-H3-Positive Tumor Cells and Tumor Vasculature.

Seaman S, Zhu Z, Saha S, Zhang XM, Yang MY, Hilton MB, Morris K, Szot C, Morris H, Swing DA, Tessarollo L, Smith SW, Degrado S, Borkin D, Jain N, Scheiermann J, Feng Y, Wang Y, Li J, Welsch D, DeCrescenzo G, Chaudhary A, Zudaire E, Klarmann KD, Keller JR, Dimitrov DS, St Croix B.

Cancer Cell. 2017 Apr 10;31(4):501-515.e8. doi: 10.1016/j.ccell.2017.03.005.

5.

GPR124 functions as a WNT7-specific coactivator of canonical β-catenin signaling.

Posokhova E, Shukla A, Seaman S, Volate S, Hilton MB, Wu B, Morris H, Swing DA, Zhou M, Zudaire E, Rubin JS, St Croix B.

Cell Rep. 2015 Jan 13;10(2):123-30. doi: 10.1016/j.celrep.2014.12.020. Epub 2014 Dec 31.

6.

Chemoprevention of metastasis.

Emenaker NJ, Zudaire E, St Croix B.

Oncotarget. 2014 Aug 30;5(16):6556-7. No abstract available.

7.

COX-2 inhibition potentiates antiangiogenic cancer therapy and prevents metastasis in preclinical models.

Xu L, Stevens J, Hilton MB, Seaman S, Conrads TP, Veenstra TD, Logsdon D, Morris H, Swing DA, Patel NL, Kalen J, Haines DC, Zudaire E, St Croix B.

Sci Transl Med. 2014 Jun 25;6(242):242ra84. doi: 10.1126/scitranslmed.3008455.

8.

Mutations in ANTXR1 cause GAPO syndrome.

Stránecký V, Hoischen A, Hartmannová H, Zaki MS, Chaudhary A, Zudaire E, Nosková L, Barešová V, Přistoupilová A, Hodaňová K, Sovová J, Hůlková H, Piherová L, Hehir-Kwa JY, de Silva D, Senanayake MP, Farrag S, Zeman J, Martásek P, Baxová A, Afifi HH, St Croix B, Brunner HG, Temtamy S, Kmoch S.

Am J Hum Genet. 2013 May 2;92(5):792-9. doi: 10.1016/j.ajhg.2013.03.023. Epub 2013 Apr 18.

9.

Aryl hydrocarbon receptor-induced adrenomedullin mediates cigarette smoke carcinogenicity in humans and mice.

Portal-Nuñez S, Shankavaram UT, Rao M, Datrice N, Atay S, Aparicio M, Camphausen KA, Fernández-Salguero PM, Chang H, Lin P, Schrump DS, Garantziotis S, Cuttitta F, Zudaire E.

Cancer Res. 2012 Nov 15;72(22):5790-800. doi: 10.1158/0008-5472.CAN-12-0818. Epub 2012 Sep 19.

10.

A computational tool for quantitative analysis of vascular networks.

Zudaire E, Gambardella L, Kurcz C, Vermeren S.

PLoS One. 2011;6(11):e27385. doi: 10.1371/journal.pone.0027385. Epub 2011 Nov 16.

11.

GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood-brain barrier.

Cullen M, Elzarrad MK, Seaman S, Zudaire E, Stevens J, Yang MY, Li X, Chaudhary A, Xu L, Hilton MB, Logsdon D, Hsiao E, Stein EV, Cuttitta F, Haines DC, Nagashima K, Tessarollo L, St Croix B.

Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5759-64. doi: 10.1073/pnas.1017192108. Epub 2011 Mar 18.

12.

Pregnancy-specific glycoprotein 1 induces endothelial tubulogenesis through interaction with cell surface proteoglycans.

Lisboa FA, Warren J, Sulkowski G, Aparicio M, David G, Zudaire E, Dveksler GS.

J Biol Chem. 2011 Mar 4;286(9):7577-86. doi: 10.1074/jbc.M110.161810. Epub 2010 Dec 30.

13.

PI3K signaling through the dual GTPase-activating protein ARAP3 is essential for developmental angiogenesis.

Gambardella L, Hemberger M, Hughes B, Zudaire E, Andrews S, Vermeren S.

Sci Signal. 2010 Oct 26;3(145):ra76. doi: 10.1126/scisignal.2001026.

14.

hnRNP A2/B1 modulates epithelial-mesenchymal transition in lung cancer cell lines.

Tauler J, Zudaire E, Liu H, Shih J, Mulshine JL.

Cancer Res. 2010 Sep 15;70(18):7137-47. doi: 10.1158/0008-5472.CAN-10-0860. Epub 2010 Aug 31.

15.

Non-peptide small molecule regulators of lymphangiogenesis.

Fang C, Miguel MA, Avis I, Martinez A, Zudaire E, Cuttitta F.

Lymphat Res Biol. 2009 Dec;7(4):189-96. doi: 10.1089/lrb.2009.0033.

16.

Abnormal lymphangiogenesis in idiopathic pulmonary fibrosis with insights into cellular and molecular mechanisms.

El-Chemaly S, Malide D, Zudaire E, Ikeda Y, Weinberg BA, Pacheco-Rodriguez G, Rosas IO, Aparicio M, Ren P, MacDonald SD, Wu HP, Nathan SD, Cuttitta F, McCoy JP, Gochuico BR, Moss J.

Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):3958-63. doi: 10.1073/pnas.0813368106. Epub 2009 Feb 23.

17.

Functional characterization of filamin a interacting protein 1-like, a novel candidate for antivascular cancer therapy.

Kwon M, Hanna E, Lorang D, He M, Quick JS, Adem A, Stevenson C, Chung JY, Hewitt SM, Zudaire E, Esposito D, Cuttitta F, Libutti SK.

Cancer Res. 2008 Sep 15;68(18):7332-41. doi: 10.1158/0008-5472.CAN-08-1087.

18.

Serum inter-alpha-trypsin inhibitor and matrix hyaluronan promote angiogenesis in fibrotic lung injury.

Garantziotis S, Zudaire E, Trempus CS, Hollingsworth JW, Jiang D, Lancaster LH, Richardson E, Zhuo L, Cuttitta F, Brown KK, Noble PW, Kimata K, Schwartz DA.

Am J Respir Crit Care Med. 2008 Nov 1;178(9):939-47. doi: 10.1164/rccm.200803-386OC. Epub 2008 Aug 14.

19.

Differentially expressed nucleolar transforming growth factor-beta1 target (DENTT) exhibits an inhibitory role on tumorigenesis.

Kandalaft LE, Zudaire E, Portal-Núñez S, Cuttitta F, Jakowlew SB.

Carcinogenesis. 2008 Jun;29(6):1282-9. doi: 10.1093/carcin/bgn087. Epub 2008 Apr 1.

20.

Intracellular proadrenomedullin-derived peptides decorate the microtubules and contribute to cytoskeleton function.

Sackett DL, Ozbun L, Zudaire E, Wessner L, Chirgwin JM, Cuttitta F, Martínez A.

Endocrinology. 2008 Jun;149(6):2888-98. doi: 10.1210/en.2007-1763. Epub 2008 Mar 6.

21.

The aryl hydrocarbon receptor repressor is a putative tumor suppressor gene in multiple human cancers.

Zudaire E, Cuesta N, Murty V, Woodson K, Adams L, Gonzalez N, Martínez A, Narayan G, Kirsch I, Franklin W, Hirsch F, Birrer M, Cuttitta F.

J Clin Invest. 2008 Feb;118(2):640-50. doi: 10.1172/JCI30024.

22.

Molecular basis for agonist selectivity and activation of the orphan bombesin receptor subtype 3 receptor.

Gonzalez N, Hocart SJ, Portal-Nuñez S, Mantey SA, Nakagawa T, Zudaire E, Coy DH, Jensen RT.

J Pharmacol Exp Ther. 2008 Feb;324(2):463-74. Epub 2007 Nov 15.

23.

Localization and expression of MUC5B and MUC7 mucins in pediatric sinus mucosa.

Peñia MT, Aujla PK, Zudaire E, Watson AM, Przygodzki R, Zalzal GH, Rose MC.

Ann Otol Rhinol Laryngol. 2007 May;116(5):389-97.

PMID:
17561770
24.

IFN regulatory factor-2 regulates macrophage apoptosis through a STAT1/3- and caspase-1-dependent mechanism.

Cuesta N, Nhu QM, Zudaire E, Polumuri S, Cuttitta F, Vogel SN.

J Immunol. 2007 Mar 15;178(6):3602-11.

25.

The central role of adrenomedullin in host defense.

Zudaire E, Portal-Núñez S, Cuttitta F.

J Leukoc Biol. 2006 Aug;80(2):237-44. Epub 2006 Jun 12. Review.

PMID:
16769769
26.

Adrenomedullin is a cross-talk molecule that regulates tumor and mast cell function during human carcinogenesis.

Zudaire E, Martínez A, Garayoa M, Pío R, Kaur G, Woolhiser MR, Metcalfe DD, Hook WA, Siraganian RP, Guise TA, Chirgwin JM, Cuttitta F.

Am J Pathol. 2006 Jan;168(1):280-91.

27.

Characterization of adrenomedullin in birds.

Zudaire E, Cuesta N, Martínez A, Cuttitta F.

Gen Comp Endocrinol. 2005 Aug;143(1):10-20. Epub 2005 Mar 29.

PMID:
15993100
28.

Identification of adrenomedullin in avian type II pneumocytes: increased expression after exposure to air pollutants.

Cuesta N, Martínez A, Cuttitta F, Zudaire E.

J Histochem Cytochem. 2005 Jun;53(6):773-80.

PMID:
15928326
29.

Inhibitors of the arachidonic acid pathway and peroxisome proliferator-activated receptor ligands have superadditive effects on lung cancer growth inhibition.

Avis I, Martínez A, Tauler J, Zudaire E, Mayburd A, Abu-Ghazaleh R, Ondrey F, Mulshine JL.

Cancer Res. 2005 May 15;65(10):4181-90.

30.

Gastrin-releasing peptide (GRP) induces angiogenesis and the specific GRP blocker 77427 inhibits tumor growth in vitro and in vivo.

Martínez A, Zudaire E, Julián M, Moody TW, Cuttitta F.

Oncogene. 2005 Jun 9;24(25):4106-13.

PMID:
15750618
31.

Using peripheral blood mononuclear cells to determine a gene expression profile of acute ischemic stroke: a pilot investigation.

Moore DF, Li H, Jeffries N, Wright V, Cooper RA Jr, Elkahloun A, Gelderman MP, Zudaire E, Blevins G, Yu H, Goldin E, Baird AE.

Circulation. 2005 Jan 18;111(2):212-21. Epub 2005 Jan 3.

PMID:
15630028
32.

Proadrenomedullin NH2-terminal 20 peptide is a potent angiogenic factor, and its inhibition results in reduction of tumor growth.

Martínez A, Zudaire E, Portal-Núñez S, Guédez L, Libutti SK, Stetler-Stevenson WG, Cuttitta F.

Cancer Res. 2004 Sep 15;64(18):6489-94.

33.

Characterization of adrenomedullin in non-human primates.

Zudaire E, Martínez A, Ozbun LL, Cuttitta F.

Biochem Biophys Res Commun. 2004 Sep 3;321(4):859-69.

PMID:
15358106
34.

Expression of complement factor H by lung cancer cells: effects on the activation of the alternative pathway of complement.

Ajona D, Castaño Z, Garayoa M, Zudaire E, Pajares MJ, Martinez A, Cuttitta F, Montuenga LM, Pio R.

Cancer Res. 2004 Sep 1;64(17):6310-8.

35.

Dietary influences over proliferating cell nuclear antigen expression in the locust midgut.

Zudaire E, Simpson SJ, Illa I, Montuenga LM.

J Exp Biol. 2004 Jun;207(Pt 13):2255-65.

36.

Adrenomedullin and cancer.

Zudaire E, Martínez A, Cuttitta F.

Regul Pept. 2003 Apr 15;112(1-3):175-83. Review.

PMID:
12667640
37.

Regulation of pancreatic physiology by adrenomedullin and its binding protein.

Zudaire E, Cuttitta F, Martínez A.

Regul Pept. 2003 Apr 15;112(1-3):121-30. Review.

PMID:
12667633
38.

Adrenomedullin expression and function in the rat carotid body.

Martínez A, Saldise L, Ramírez MJ, Belzunegui S, Zudaire E, Luquin MR, Cuttitta F.

J Endocrinol. 2003 Jan;176(1):95-102.

PMID:
12525253
39.

Adrenomedullin functions as an important tumor survival factor in human carcinogenesis.

Cuttitta F, Pío R, Garayoa M, Zudaire E, Julián M, Elsasser TH, Montuenga LM, Martínez A.

Microsc Res Tech. 2002 Apr 15;57(2):110-9. Review.

PMID:
11921362
41.

Localization of adrenomedullin-like immunoreactivity in the hypothalamo-hypophysial system of amphibians.

González A, Marín O, Sánchez-Camacho C, José Peña J, Zudaire E, Martínez A, Cuttitta F, Muñoz M.

Neurosci Lett. 1998 Feb 6;242(1):13-6.

PMID:
9580198
42.

Impaired intestinal sugar transport in cirrhotic rats: correction by low doses of insulin-like growth factor I.

Castilla-Cortazar I, Prieto J, Urdaneta E, Pascual M, Nuñez M, Zudaire E, Garcia M, Quiroga J, Santidrian S.

Gastroenterology. 1997 Oct;113(4):1180-7.

PMID:
9322513

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