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Items: 1 to 50 of 62

1.

Validation of two short questionnaires assessing physical activity in colorectal cancer patients.

Henriksen HB, Berntsen S, Paur I, Zucknick M, Skjetne AJ, Bøhn SK, Henriksen C, Smeland S, Carlsen MH, Blomhoff R.

BMC Sports Sci Med Rehabil. 2018 May 29;10:8. doi: 10.1186/s13102-018-0096-2. eCollection 2018.

2.

Maternal concentrations of human chorionic gonadotrophin in very early IVF pregnancies and duration of pregnancy: a follow-up study.

Tanbo TG, Zucknick M, Eskild A.

Reprod Biomed Online. 2018 May 2. pii: S1472-6483(18)30229-3. doi: 10.1016/j.rbmo.2018.04.048. [Epub ahead of print]

PMID:
29773310
3.

Development of bimanual performance in young children with cerebral palsy.

Klevberg GL, Elvrum AG, Zucknick M, Elkjaer S, Østensjø S, Krumlinde-Sundholm L, Kjeken I, Jahnsen R.

Dev Med Child Neurol. 2018 May;60(5):490-497. doi: 10.1111/dmcn.13680. Epub 2018 Feb 2.

PMID:
29392717
4.

Tumor necrosis factor receptor signaling is a driver of chronic lymphocytic leukemia that can be therapeutically targeted by the flavonoid wogonin.

Dürr C, Hanna BS, Schulz A, Lucas F, Zucknick M, Benner A, Clear A, Ohl S, Öztürk S, Zenz T, Stilgenbauer S, Li-Weber M, Krammer PH, Gribben JG, Lichter P, Seiffert M.

Haematologica. 2018 Apr;103(4):688-697. doi: 10.3324/haematol.2017.177808. Epub 2018 Jan 11.

5.

Uptake and release of amino acids in the fetal-placental unit in human pregnancies.

Holm MB, Bastani NE, Holme AM, Zucknick M, Jansson T, Refsum H, Mørkrid L, Blomhoff R, Henriksen T, Michelsen TM.

PLoS One. 2017 Oct 5;12(10):e0185760. doi: 10.1371/journal.pone.0185760. eCollection 2017.

6.

NFATC1 activation by DNA hypomethylation in chronic lymphocytic leukemia correlates with clinical staging and can be inhibited by ibrutinib.

Wolf C, Garding A, Filarsky K, Bahlo J, Robrecht S, Becker N, Zucknick M, Rouhi A, Weigel A, Claus R, Weichenhan D, Eichhorst B, Fischer K, Hallek M, Kuchenbauer F, Plass C, Döhner H, Stilgenbauer S, Lichter P, Mertens D.

Int J Cancer. 2018 Jan 15;142(2):322-333. doi: 10.1002/ijc.31057. Epub 2017 Oct 9.

PMID:
28921505
7.

Estrogen Receptor α, a Sex-Dependent Predictor of Aggressiveness in Nonfunctioning Pituitary Adenomas: SSTR and Sex Hormone Receptor Distribution in NFPA.

Øystese KA, Casar-Borota O, Normann KR, Zucknick M, Berg JP, Bollerslev J.

J Clin Endocrinol Metab. 2017 Sep 1;102(9):3581-3590. doi: 10.1210/jc.2017-00792.

PMID:
28911153
8.

Integration of Multiple Genomic Data Sources in a Bayesian Cox Model for Variable Selection and Prediction.

Treppmann T, Ickstadt K, Zucknick M.

Comput Math Methods Med. 2017;2017:7340565. doi: 10.1155/2017/7340565. Epub 2017 Jul 30.

9.

Early postoperative growth in non-functioning pituitary adenomas; A tool to tailor safe follow-up.

Øystese KA, Zucknick M, Casar-Borota O, Ringstad G, Bollerslev J.

Endocrine. 2017 Jul;57(1):35-45. doi: 10.1007/s12020-017-1314-5. Epub 2017 May 17.

PMID:
28516382
10.

Preeclampsia in kidney transplanted women; Outcomes and a simple prognostic risk score system.

Majak GB, Reisæter AV, Zucknick M, Lorentzen B, Vangen S, Henriksen T, Michelsen TM.

PLoS One. 2017 Mar 20;12(3):e0173420. doi: 10.1371/journal.pone.0173420. eCollection 2017.

11.

The Norwegian dietary guidelines and colorectal cancer survival (CRC-NORDIET) study: a food-based multicentre randomized controlled trial.

Henriksen HB, Ræder H, Bøhn SK, Paur I, Kværner AS, Billington SÅ, Eriksen MT, Wiedsvang G, Erlund I, Færden A, Veierød MB, Zucknick M, Smeland S, Blomhoff R.

BMC Cancer. 2017 Jan 30;17(1):83. doi: 10.1186/s12885-017-3072-4.

12.

DMBT1 expression in biliary carcinogenesis with correlation of clinicopathological data.

Goeppert B, Roessler S, Becker N, Zucknick M, Vogel MN, Warth A, Pathil-Warth A, Mehrabi A, Schirmacher P, Mollenhauer J, Renner M.

Histopathology. 2017 Jun;70(7):1064-1071. doi: 10.1111/his.13175. Epub 2017 Mar 28.

PMID:
28130841
13.

Krüppel-like factor 4 (KLF4) inactivation in chronic lymphocytic leukemia correlates with promoter DNA-methylation and can be reversed by inhibition of NOTCH signaling.

Filarsky K, Garding A, Becker N, Wolf C, Zucknick M, Claus R, Weichenhan D, Plass C, Döhner H, Stilgenbauer S, Lichter P, Mertens D.

Haematologica. 2016 Jun;101(6):e249-53. doi: 10.3324/haematol.2015.138172. Epub 2016 Apr 14. No abstract available.

14.

Tp53/p53 status in keratoacanthomas.

Joshi S, Schjølberg AR, Ekstrøm PO, De Angelis PM, Zucknick M, Andersen SN, Clausen OP.

J Cutan Pathol. 2016 Jul;43(7):571-8. doi: 10.1111/cup.12713. Epub 2016 Apr 20.

PMID:
27020606
15.

LOC283731 promoter hypermethylation prognosticates survival after radiochemotherapy in IDH1 wild-type glioblastoma patients.

Mock A, Geisenberger C, Orlik C, Warta R, Schwager C, Jungk C, Dutruel C, Geiselhart L, Weichenhan D, Zucknick M, Nied AK, Friauf S, Exner J, Capper D, Hartmann C, Lahrmann B, Grabe N, Debus J, von Deimling A, Popanda O, Plass C, Unterberg A, Abdollahi A, Schmezer P, Herold-Mende C.

Int J Cancer. 2016 Jul 15;139(2):424-32. doi: 10.1002/ijc.30069. Epub 2016 Mar 18.

16.

SNPs in transporter and metabolizing genes as predictive markers for oxaliplatin treatment in colorectal cancer patients.

Kap EJ, Seibold P, Scherer D, Habermann N, Balavarca Y, Jansen L, Zucknick M, Becker N, Hoffmeister M, Ulrich A, Benner A, Ulrich CM, Burwinkel B, Brenner H, Chang-Claude J.

Int J Cancer. 2016 Jun 15;138(12):2993-3001. doi: 10.1002/ijc.30026. Epub 2016 Feb 19.

17.

Gene promoter methylation signature predicts survival of head and neck squamous cell carcinoma patients.

Kostareli E, Hielscher T, Zucknick M, Baboci L, Wichmann G, Holzinger D, Mücke O, Pawlita M, Del Mistro A, Boscolo-Rizzo P, Da Mosto MC, Tirelli G, Plinkert P, Dietz A, Plass C, Weichenhan D, Hess J.

Epigenetics. 2016;11(1):61-73. doi: 10.1080/15592294.2015.1137414. Epub 2016 Jan 19.

18.

Circulating miRNAs with prognostic value in metastatic breast cancer and for early detection of metastasis.

Madhavan D, Peng C, Wallwiener M, Zucknick M, Nees J, Schott S, Rudolph A, Riethdorf S, Trumpp A, Pantel K, Sohn C, Chang-Claude J, Schneeweiss A, Burwinkel B.

Carcinogenesis. 2016 May;37(5):461-70. doi: 10.1093/carcin/bgw008. Epub 2016 Jan 19.

PMID:
26785733
19.

Major histocompatibility complex class I expression impacts on patient survival and type and density of immune cells in biliary tract cancer.

Goeppert B, Frauenschuh L, Zucknick M, Roessler S, Mehrabi A, Hafezi M, Stenzinger A, Warth A, Pathil A, Renner M, Schirmacher P, Weichert W.

Br J Cancer. 2015 Nov 3;113(9):1343-9. doi: 10.1038/bjc.2015.337. Epub 2015 Oct 13.

20.

Nonidentical twins: Comparison of frequentist and Bayesian lasso for Cox models.

Zucknick M, Saadati M, Benner A.

Biom J. 2015 Nov;57(6):959-81. doi: 10.1002/bimj.201400160. Epub 2015 Sep 29.

PMID:
26417963
21.

Head-to-Head Comparison and Evaluation of 92 Plasma Protein Biomarkers for Early Detection of Colorectal Cancer in a True Screening Setting.

Chen H, Zucknick M, Werner S, Knebel P, Brenner H.

Clin Cancer Res. 2015 Jul 15;21(14):3318-26. doi: 10.1158/1078-0432.CCR-14-3051. Epub 2015 May 26.

22.

DNA methylation array analyses identified breast cancer-associated HYAL2 methylation in peripheral blood.

Yang R, Pfütze K, Zucknick M, Sutter C, Wappenschmidt B, Marme F, Qu B, Cuk K, Engel C, Schott S, Schneeweiss A, Brenner H, Claus R, Plass C, Bugert P, Hoth M, Sohn C, Schmutzler R, Bartram CR, Burwinkel B.

Int J Cancer. 2015 Apr 15;136(8):1845-55. doi: 10.1002/ijc.29205. Epub 2014 Sep 24.

23.

RASA4 undergoes DNA hypermethylation in resistant juvenile myelomonocytic leukemia.

Poetsch AR, Lipka DB, Witte T, Claus R, Nöllke P, Zucknick M, Olk-Batz C, Fluhr S, Dworzak M, De Moerloose B, Starý J, Zecca M, Hasle H, Schmugge M, van den Heuvel-Eibrink MM, Locatelli F, Niemeyer CM, Flotho C, Plass C.

Epigenetics. 2014 Sep;9(9):1252-60. doi: 10.4161/epi.29941. Epub 2014 Jul 31.

24.

Intratumor DNA methylation heterogeneity reflects clonal evolution in aggressive prostate cancer.

Brocks D, Assenov Y, Minner S, Bogatyrova O, Simon R, Koop C, Oakes C, Zucknick M, Lipka DB, Weischenfeldt J, Feuerbach L, Cowper-Sal Lari R, Lupien M, Brors B, Korbel J, Schlomm T, Tanay A, Sauter G, Gerhäuser C, Plass C; ICGC Early Onset Prostate Cancer Project.

Cell Rep. 2014 Aug 7;8(3):798-806. doi: 10.1016/j.celrep.2014.06.053. Epub 2014 Jul 24.

25.

Early aberrant DNA methylation events in a mouse model of acute myeloid leukemia.

Sonnet M, Claus R, Becker N, Zucknick M, Petersen J, Lipka DB, Oakes CC, Andrulis M, Lier A, Milsom MD, Witte T, Gu L, Kim-Wanner SZ, Schirmacher P, Wulfert M, Gattermann N, Lübbert M, Rosenbauer F, Rehli M, Bullinger L, Weichenhan D, Plass C.

Genome Med. 2014 Apr 30;6(4):34. doi: 10.1186/gm551. eCollection 2014.

26.

Validation of ZAP-70 methylation and its relative significance in predicting outcome in chronic lymphocytic leukemia.

Claus R, Lucas DM, Ruppert AS, Williams KE, Weng D, Patterson K, Zucknick M, Oakes CC, Rassenti LZ, Greaves AW, Geyer S, Wierda WG, Brown JR, Gribben JG, Barrientos JC, Rai KR, Kay NE, Kipps TJ, Shields P, Zhao W, Grever MR, Plass C, Byrd JC.

Blood. 2014 Jul 3;124(1):42-8. doi: 10.1182/blood-2014-02-555722. Epub 2014 May 27. Erratum in: Blood. 2014 Sep 11;124(11):1848.

27.

Plasma DNA integrity as a biomarker for primary and metastatic breast cancer and potential marker for early diagnosis.

Madhavan D, Wallwiener M, Bents K, Zucknick M, Nees J, Schott S, Cuk K, Riethdorf S, Trumpp A, Pantel K, Sohn C, Schneeweiss A, Surowy H, Burwinkel B.

Breast Cancer Res Treat. 2014 Jul;146(1):163-74. doi: 10.1007/s10549-014-2946-2. Epub 2014 May 17.

PMID:
24838941
28.

Evolution of DNA methylation is linked to genetic aberrations in chronic lymphocytic leukemia.

Oakes CC, Claus R, Gu L, Assenov Y, Hüllein J, Zucknick M, Bieg M, Brocks D, Bogatyrova O, Schmidt CR, Rassenti L, Kipps TJ, Mertens D, Lichter P, Döhner H, Stilgenbauer S, Byrd JC, Zenz T, Plass C.

Cancer Discov. 2014 Mar;4(3):348-61. doi: 10.1158/2159-8290.CD-13-0349. Epub 2013 Dec 19.

29.

Plasma microRNA panel for minimally invasive detection of breast cancer.

Cuk K, Zucknick M, Madhavan D, Schott S, Golatta M, Heil J, Marmé F, Turchinovich A, Sinn P, Sohn C, Junkermann H, Schneeweiss A, Burwinkel B.

PLoS One. 2013 Oct 23;8(10):e76729. doi: 10.1371/journal.pone.0076729. eCollection 2013.

30.

Prognostic impact of tumour-infiltrating immune cells on biliary tract cancer.

Goeppert B, Frauenschuh L, Zucknick M, Stenzinger A, Andrulis M, Klauschen F, Joehrens K, Warth A, Renner M, Mehrabi A, Hafezi M, Thelen A, Schirmacher P, Weichert W.

Br J Cancer. 2013 Nov 12;109(10):2665-74. doi: 10.1038/bjc.2013.610. Epub 2013 Oct 17.

31.

Global alterations of DNA methylation in cholangiocarcinoma target the Wnt signaling pathway.

Goeppert B, Konermann C, Schmidt CR, Bogatyrova O, Geiselhart L, Ernst C, Gu L, Becker N, Zucknick M, Mehrabi A, Hafezi M, Klauschen F, Stenzinger A, Warth A, Breuhahn K, Renner M, Weichert W, Schirmacher P, Plass C, Weichenhan D.

Hepatology. 2014 Feb;59(2):544-54. doi: 10.1002/hep.26721. Epub 2013 Dec 24.

PMID:
24002901
32.

Defective DROSHA processing contributes to downregulation of MiR-15/-16 in chronic lymphocytic leukemia.

Allegra D, Bilan V, Garding A, Döhner H, Stilgenbauer S, Kuchenbauer F, Mertens D, Zucknick M.

Leukemia. 2014 Jan;28(1):98-107. doi: 10.1038/leu.2013.246. Epub 2013 Aug 26. Erratum in: Leukemia. 2014 Dec;28(12):2427. Zucknick, Manuela [Added].

PMID:
23974981
33.

Early epigenetic downregulation of WNK2 kinase during pancreatic ductal adenocarcinoma development.

Dutruel C, Bergmann F, Rooman I, Zucknick M, Weichenhan D, Geiselhart L, Kaffenberger T, Rachakonda PS, Bauer A, Giese N, Hong C, Xie H, Costello JF, Hoheisel J, Kumar R, Rehli M, Schirmacher P, Werner J, Plass C, Popanda O, Schmezer P.

Oncogene. 2014 Jun 26;33(26):3401-10. doi: 10.1038/onc.2013.312. Epub 2013 Aug 5.

PMID:
23912455
34.

Differential expression and methylation of brain developmental genes define location-specific subsets of pilocytic astrocytoma.

Lambert SR, Witt H, Hovestadt V, Zucknick M, Kool M, Pearson DM, Korshunov A, Ryzhova M, Ichimura K, Jabado N, Fontebasso AM, Lichter P, Pfister SM, Collins VP, Jones DT.

Acta Neuropathol. 2013 Aug;126(2):291-301. doi: 10.1007/s00401-013-1124-7. Epub 2013 May 10.

PMID:
23660940
35.

Epigenetic upregulation of lncRNAs at 13q14.3 in leukemia is linked to the In Cis downregulation of a gene cluster that targets NF-kB.

Garding A, Bhattacharya N, Claus R, Ruppel M, Tschuch C, Filarsky K, Idler I, Zucknick M, Caudron-Herger M, Oakes C, Fleig V, Keklikoglou I, Allegra D, Serra L, Thakurela S, Tiwari V, Weichenhan D, Benner A, Radlwimmer B, Zentgraf H, Wiemann S, Rippe K, Plass C, Döhner H, Lichter P, Stilgenbauer S, Mertens D.

PLoS Genet. 2013 Apr;9(4):e1003373. doi: 10.1371/journal.pgen.1003373. Epub 2013 Apr 4.

36.

Decitabine induces very early in vivo DNA methylation changes in blasts from patients with acute myeloid leukemia.

Claus R, Pfeifer D, Almstedt M, Zucknick M, Hackanson B, Plass C, Lübbert M.

Leuk Res. 2013 Feb;37(2):190-6. doi: 10.1016/j.leukres.2012.10.015. Epub 2012 Nov 15.

PMID:
23158571
37.

Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma.

Sturm D, Witt H, Hovestadt V, Khuong-Quang DA, Jones DT, Konermann C, Pfaff E, Tönjes M, Sill M, Bender S, Kool M, Zapatka M, Becker N, Zucknick M, Hielscher T, Liu XY, Fontebasso AM, Ryzhova M, Albrecht S, Jacob K, Wolter M, Ebinger M, Schuhmann MU, van Meter T, Frühwald MC, Hauch H, Pekrun A, Radlwimmer B, Niehues T, von Komorowski G, Dürken M, Kulozik AE, Madden J, Donson A, Foreman NK, Drissi R, Fouladi M, Scheurlen W, von Deimling A, Monoranu C, Roggendorf W, Herold-Mende C, Unterberg A, Kramm CM, Felsberg J, Hartmann C, Wiestler B, Wick W, Milde T, Witt O, Lindroth AM, Schwartzentruber J, Faury D, Fleming A, Zakrzewska M, Liberski PP, Zakrzewski K, Hauser P, Garami M, Klekner A, Bognar L, Morrissy S, Cavalli F, Taylor MD, van Sluis P, Koster J, Versteeg R, Volckmann R, Mikkelsen T, Aldape K, Reifenberger G, Collins VP, Majewski J, Korshunov A, Lichter P, Plass C, Jabado N, Pfister SM.

Cancer Cell. 2012 Oct 16;22(4):425-37. doi: 10.1016/j.ccr.2012.08.024.

38.

F2A sequence linking MGMT(P140K) and MDR1 in a bicistronic lentiviral vector enables efficient chemoprotection of haematopoietic stem cells.

Maier P, Heckmann D, Spier I, Laufs S, Zucknick M, Allgayer H, Fruehauf S, Zeller WJ, Wenz F.

Cancer Gene Ther. 2012 Nov;19(11):802-10. doi: 10.1038/cgt.2012.67. Epub 2012 Oct 5.

PMID:
23037811
39.

Circulating miRNAs as surrogate markers for circulating tumor cells and prognostic markers in metastatic breast cancer.

Madhavan D, Zucknick M, Wallwiener M, Cuk K, Modugno C, Scharpff M, Schott S, Heil J, Turchinovich A, Yang R, Benner A, Riethdorf S, Trumpp A, Sohn C, Pantel K, Schneeweiss A, Burwinkel B.

Clin Cancer Res. 2012 Nov 1;18(21):5972-82. doi: 10.1158/1078-0432.CCR-12-1407. Epub 2012 Sep 4.

40.

Circulating microRNAs in plasma as early detection markers for breast cancer.

Cuk K, Zucknick M, Heil J, Madhavan D, Schott S, Turchinovich A, Arlt D, Rath M, Sohn C, Benner A, Junkermann H, Schneeweiss A, Burwinkel B.

Int J Cancer. 2013 Apr 1;132(7):1602-12. doi: 10.1002/ijc.27799. Epub 2012 Sep 14.

41.

Extensive promoter DNA hypermethylation and hypomethylation is associated with aberrant microRNA expression in chronic lymphocytic leukemia.

Baer C, Claus R, Frenzel LP, Zucknick M, Park YJ, Gu L, Weichenhan D, Fischer M, Pallasch CP, Herpel E, Rehli M, Byrd JC, Wendtner CM, Plass C.

Cancer Res. 2012 Aug 1;72(15):3775-85. Epub 2012 Jun 18.

42.

Quantitative DNA methylation analysis identifies a single CpG dinucleotide important for ZAP-70 expression and predictive of prognosis in chronic lymphocytic leukemia.

Claus R, Lucas DM, Stilgenbauer S, Ruppert AS, Yu L, Zucknick M, Mertens D, Bühler A, Oakes CC, Larson RA, Kay NE, Jelinek DF, Kipps TJ, Rassenti LZ, Gribben JG, Döhner H, Heerema NA, Marcucci G, Plass C, Byrd JC.

J Clin Oncol. 2012 Jul 10;30(20):2483-91. doi: 10.1200/JCO.2011.39.3090. Epub 2012 May 7.

43.

Monosomal karyotype in adult acute myeloid leukemia: prognostic impact and outcome after different treatment strategies.

Kayser S, Zucknick M, Döhner K, Krauter J, Köhne CH, Horst HA, Held G, von Lilienfeld-Toal M, Wilhelm S, Rummel M, Germing U, Götze K, Nachbaur D, Schlegelberger B, Göhring G, Späth D, Morlok C, Teleanu V, Ganser A, Döhner H, Schlenk RF; German-Austrian AML Study Group.

Blood. 2012 Jan 12;119(2):551-8. doi: 10.1182/blood-2011-07-367508. Epub 2011 Nov 16.

44.

A Lentiviral CXCR4 overexpression and knockdown model in colorectal cancer cell lines reveals plerixafor-dependent suppression of SDF-1α-induced migration and invasion.

Heckmann D, Laufs S, Maier P, Zucknick M, Giordano FA, Veldwijk MR, Eckstein V, Wenz F, Zeller WJ, Fruehauf S, Allgayer H.

Onkologie. 2011;34(10):502-8. doi: 10.1159/000332390. Epub 2011 Sep 20.

PMID:
21985848
45.

Quantitative analyses of DAPK1 methylation in AML and MDS.

Claus R, Hackanson B, Poetsch AR, Zucknick M, Sonnet M, Blagitko-Dorfs N, Hiller J, Wilop S, Brümmendorf TH, Galm O, Platzbecker U, Byrd JC, Döhner K, Döhner H, Lübbert M, Plass C.

Int J Cancer. 2012 Jul 15;131(2):E138-42. doi: 10.1002/ijc.26429. Epub 2011 Nov 28.

46.

Aberrant DNA methylation characterizes juvenile myelomonocytic leukemia with poor outcome.

Olk-Batz C, Poetsch AR, Nöllke P, Claus R, Zucknick M, Sandrock I, Witte T, Strahm B, Hasle H, Zecca M, Stary J, Bergstraesser E, De Moerloose B, Trebo M, van den Heuvel-Eibrink MM, Wojcik D, Locatelli F, Plass C, Niemeyer CM, Flotho C; European Working Group of Myelodysplastic Syndromes in Childhood (EWOG-MDS).

Blood. 2011 May 5;117(18):4871-80. doi: 10.1182/blood-2010-08-298968. Epub 2011 Mar 15.

47.

The impact of therapy-related acute myeloid leukemia (AML) on outcome in 2853 adult patients with newly diagnosed AML.

Kayser S, Döhner K, Krauter J, Köhne CH, Horst HA, Held G, von Lilienfeld-Toal M, Wilhelm S, Kündgen A, Götze K, Rummel M, Nachbaur D, Schlegelberger B, Göhring G, Späth D, Morlok C, Zucknick M, Ganser A, Döhner H, Schlenk RF; German-Austrian AMLSG.

Blood. 2011 Feb 17;117(7):2137-45. doi: 10.1182/blood-2010-08-301713. Epub 2010 Dec 2.

48.

Assessment and optimisation of normalisation methods for dual-colour antibody microarrays.

Sill M, Schröder C, Hoheisel JD, Benner A, Zucknick M.

BMC Bioinformatics. 2010 Nov 12;11:556. doi: 10.1186/1471-2105-11-556.

49.

Protein expression analysis of chronic lymphocytic leukemia defines the effect of genetic aberrations and uncovers a correlation of CDK4, P27 and P53 with hierarchical risk.

Winkler D, Schneider C, Zucknick M, Bögelein D, Schulze K, Zenz T, Mohr J, Philippen A, Huber H, Bühler A, Habermann A, Benner A, Döhner H, Stilgenbauer S, Mertens D.

Haematologica. 2010 Nov;95(11):1880-8. doi: 10.3324/haematol.2010.025734. Epub 2010 Aug 16.

50.

IDH1 and IDH2 mutations are frequent genetic alterations in acute myeloid leukemia and confer adverse prognosis in cytogenetically normal acute myeloid leukemia with NPM1 mutation without FLT3 internal tandem duplication.

Paschka P, Schlenk RF, Gaidzik VI, Habdank M, Krönke J, Bullinger L, Späth D, Kayser S, Zucknick M, Götze K, Horst HA, Germing U, Döhner H, Döhner K.

J Clin Oncol. 2010 Aug 1;28(22):3636-43. doi: 10.1200/JCO.2010.28.3762. Epub 2010 Jun 21.

PMID:
20567020

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