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Items: 1 to 50 of 100

1.

A bio-inspired approach to ligand design: folding single-chain peptoids to chelate a multimetallic cluster.

Nguyen AI, Spencer RK, Anderson CL, Zuckermann RN.

Chem Sci. 2018 Nov 15;9(47):8806-8813. doi: 10.1039/c8sc04240c. eCollection 2018 Dec 21.

2.

Linking two worlds in polymer chemistry: The influence of block uniformity and dispersity in amphiphilic block copolypeptoids on their self-assembly.

Gangloff N, Höferth M, Stepanenko V, Sochor B, Schummer B, Nickel J, Walles H, Hanke R, Würthner F, Zuckermann RN, Luxenhofer R.

Biopolymers. 2019 Feb 7:e23259. doi: 10.1002/bip.23259. [Epub ahead of print]

PMID:
30730564
3.

Resolving the Morphology of Peptoid Vesicles at the 1 nm Length Scale Using Cryogenic Electron Microscopy.

Jiang X, Spencer RK, Sun J, Ophus C, Zuckermann RN, Downing KH, Balsara NP.

J Phys Chem B. 2019 Feb 7;123(5):1195-1205. doi: 10.1021/acs.jpcb.8b11752. Epub 2019 Jan 25.

PMID:
30629439
4.

Self-assembling peptides cross-linked with genipin: resilient hydrogels and self-standing electrospun scaffolds for tissue engineering applications.

Pugliese R, Maleki M, Zuckermann RN, Gelain F.

Biomater Sci. 2018 Dec 18;7(1):76-91. doi: 10.1039/c8bm00825f.

PMID:
30475373
5.

Conformations of peptoids in nanosheets result from the interplay of backbone energetics and intermolecular interactions.

Edison JR, Spencer RK, Butterfoss GL, Hudson BC, Hochbaum AI, Paravastu AK, Zuckermann RN, Whitelam S.

Proc Natl Acad Sci U S A. 2018 May 29;115(22):5647-5651. doi: 10.1073/pnas.1800397115. Epub 2018 May 14.

6.

Evidence for cis Amide Bonds in Peptoid Nanosheets.

Hudson BC, Battigelli A, Connolly MD, Edison J, Spencer RK, Whitelam S, Zuckermann RN, Paravastu AK.

J Phys Chem Lett. 2018 May 17;9(10):2574-2578. doi: 10.1021/acs.jpclett.8b01040. Epub 2018 May 2.

7.

Glycosylated Peptoid Nanosheets as a Multivalent Scaffold for Protein Recognition.

Battigelli A, Kim JH, Dehigaspitiya DC, Proulx C, Robertson EJ, Murray DJ, Rad B, Kirshenbaum K, Zuckermann RN.

ACS Nano. 2018 Mar 27;12(3):2455-2465. doi: 10.1021/acsnano.7b08018. Epub 2018 Mar 7.

8.

Using biomimetic polymers in place of noncollagenous proteins to achieve functional remineralization of dentin tissues.

Chien YC, Tao J, Saeki K, Chin AF, Lau JL, Chen CL, Zuckermann RN, Marshall SJ, Marshall GW, De Yoreo JJ.

ACS Biomater Sci Eng. 2017 Dec 11;3(12):3469-3479. doi: 10.1021/acsbiomaterials.7b00378. Epub 2017 Oct 18.

9.

Universal Relationship between Molecular Structure and Crystal Structure in Peptoid Polymers and Prevalence of the cis Backbone Conformation.

Greer DR, Stolberg MA, Kundu J, Spencer RK, Pascal T, Prendergast D, Balsara NP, Zuckermann RN.

J Am Chem Soc. 2018 Jan 17;140(2):827-833. doi: 10.1021/jacs.7b11891. Epub 2018 Jan 8.

10.

Foldamer hypothesis for the growth and sequence differentiation of prebiotic polymers.

Guseva E, Zuckermann RN, Dill KA.

Proc Natl Acad Sci U S A. 2017 Sep 5;114(36):E7460-E7468. doi: 10.1073/pnas.1620179114. Epub 2017 Aug 22.

11.

Sequence-Dependent Self-Assembly and Structural Diversity of Islet Amyloid Polypeptide-Derived β-Sheet Fibrils.

Wang ST, Lin Y, Spencer RK, Thomas MR, Nguyen AI, Amdursky N, Pashuck ET, Skaalure SC, Song CY, Parmar PA, Morgan RM, Ercius P, Aloni S, Zuckermann RN, Stevens MM.

ACS Nano. 2017 Sep 26;11(9):8579-8589. doi: 10.1021/acsnano.7b02325. Epub 2017 Aug 3.

12.

Morphology-Driven Control of Metabolite Selectivity Using Nanostructure-Initiator Mass Spectrometry.

Gao J, Louie KB, Steinke P, Bowen BP, Raad M, Zuckermann RN, Siuzdak G, Northen TR.

Anal Chem. 2017 Jun 20;89(12):6521-6526. doi: 10.1021/acs.analchem.7b00599. Epub 2017 May 26.

PMID:
28520405
13.

Exploring the links between peptoid antibacterial activity and toxicity.

Bolt HL, Eggimann GA, Jahoda CAB, Zuckermann RN, Sharples GJ, Cobb SL.

Medchemcomm. 2017 Feb 1;8(5):886-896. doi: 10.1039/c6md00648e. eCollection 2017 May 1.

14.

Log D versus HPLC derived hydrophobicity: The development of predictive tools to aid in the rational design of bioactive peptoids.

Bolt HL, Williams CEJ, Brooks RV, Zuckermann RN, Cobb SL, Bromley EHC.

Biopolymers. 2017 Jul;108(4). doi: 10.1002/bip.23014.

15.

Oxygen K Edge Scattering from Bulk Comb Diblock Copolymer Reveals Extended, Ordered Backbones above Lamellar Order-Disorder Transition.

Kortright JB, Sun J, Spencer RK, Jiang X, Zuckermann RN.

J Phys Chem B. 2017 Jan 12;121(1):298-305. doi: 10.1021/acs.jpcb.6b09925. Epub 2016 Dec 27.

PMID:
27960255
16.

Molecular Engineering of the Peptoid Nanosheet Hydrophobic Core.

Robertson EJ, Proulx C, Su JK, Garcia RL, Yoo S, Nehls EM, Connolly MD, Taravati L, Zuckermann RN.

Langmuir. 2016 Nov 15;32(45):11946-11957. Epub 2016 Oct 29.

PMID:
27794618
17.

Structure-Rheology Relationship in Nanosheet-Forming Peptoid Monolayers.

Robertson EJ, Nehls EM, Zuckermann RN.

Langmuir. 2016 Nov 22;32(46):12146-12158. Epub 2016 Oct 29.

PMID:
27794613
18.

On-resin N-terminal peptoid degradation: Toward mild sequencing conditions.

Proulx C, Noë F, Yoo S, Connolly MD, Zuckermann RN.

Biopolymers. 2016 Sep;106(5):726-36. doi: 10.1002/bip.22884.

PMID:
27258140
19.

Surface-Directed Assembly of Sequence-Defined Synthetic Polymers into Networks of Hexagonally Patterned Nanoribbons with Controlled Functionalities.

Chen CL, Zuckermann RN, DeYoreo JJ.

ACS Nano. 2016 May 24;10(5):5314-20. doi: 10.1021/acsnano.6b01333. Epub 2016 May 9.

PMID:
27136277
20.

Morphology and Proton Transport in Humidified Phosphonated Peptoid Block Copolymers.

Sun J, Jiang X, Siegmund A, Connolly MD, Downing KH, Balsara NP, Zuckermann RN.

Macromolecules. 2016 Apr 26;49(8):3083-3090. Epub 2016 Apr 4.

21.

Self-assembly of crystalline nanotubes from monodisperse amphiphilic diblock copolypeptoid tiles.

Sun J, Jiang X, Lund R, Downing KH, Balsara NP, Zuckermann RN.

Proc Natl Acad Sci U S A. 2016 Apr 12;113(15):3954-9. doi: 10.1073/pnas.1517169113. Epub 2016 Mar 28.

22.

Improved chemical and mechanical stability of peptoid nanosheets by photo-crosslinking the hydrophobic core.

Flood D, Proulx C, Robertson EJ, Battigelli A, Wang S, Schwartzberg AM, Zuckermann RN.

Chem Commun (Camb). 2016 Apr 4;52(26):4753-6. doi: 10.1039/c6cc00588h. Epub 2016 Feb 11.

23.

Application of Black Silicon for Nanostructure-Initiator Mass Spectrometry.

Gao J, de Raad M, Bowen BP, Zuckermann RN, Northen TR.

Anal Chem. 2016 Feb 2;88(3):1625-30. doi: 10.1021/acs.analchem.5b03452. Epub 2016 Jan 21.

24.

Design, Synthesis, Assembly, and Engineering of Peptoid Nanosheets.

Robertson EJ, Battigelli A, Proulx C, Mannige RV, Haxton TK, Yun L, Whitelam S, Zuckermann RN.

Acc Chem Res. 2016 Mar 15;49(3):379-89. doi: 10.1021/acs.accounts.5b00439. Epub 2016 Jan 7.

PMID:
26741294
25.

Implicit-Solvent Coarse-Grained Simulation with a Fluctuating Interface Reveals a Molecular Mechanism for Peptoid Monolayer Buckling.

Haxton TK, Zuckermann RN, Whitelam S.

J Chem Theory Comput. 2016 Jan 12;12(1):345-52. doi: 10.1021/acs.jctc.5b00910. Epub 2015 Dec 22.

PMID:
26647143
26.

Modeling sequence-specific polymers using anisotropic coarse-grained sites allows quantitative comparison with experiment.

Haxton TK, Mannige RV, Zuckermann RN, Whitelam S.

J Chem Theory Comput. 2015 Jan 13;11(1):303-15. doi: 10.1021/ct5010559.

PMID:
26574228
27.

Peptoid nanosheets exhibit a new secondary-structure motif.

Mannige RV, Haxton TK, Proulx C, Robertson EJ, Battigelli A, Butterfoss GL, Zuckermann RN, Whitelam S.

Nature. 2015 Oct 15;526(7573):415-20. doi: 10.1038/nature15363. Epub 2015 Oct 7.

PMID:
26444241
28.

Accelerated Submonomer Solid-Phase Synthesis of Peptoids Incorporating Multiple Substituted N-Aryl Glycine Monomers.

Proulx C, Yoo S, Connolly MD, Zuckermann RN.

J Org Chem. 2015 Nov 6;80(21):10490-7. doi: 10.1021/acs.joc.5b01449. Epub 2015 Aug 22.

PMID:
26280152
29.

Peptoid nanosheets as soluble, two-dimensional templates for calcium carbonate mineralization.

Jun JM, Altoe MV, Aloni S, Zuckermann RN.

Chem Commun (Camb). 2015 Jun 25;51(50):10218-21. doi: 10.1039/c5cc03323c. Epub 2015 May 29.

PMID:
26021742
30.

Structure-activity relationship study of novel peptoids that mimic the structure of antimicrobial peptides.

Mojsoska B, Zuckermann RN, Jenssen H.

Antimicrob Agents Chemother. 2015 Jul;59(7):4112-20. doi: 10.1128/AAC.00237-15. Epub 2015 May 4.

31.

Sequence Programmable Peptoid Polymers for Diverse Materials Applications.

Knight AS, Zhou EY, Francis MB, Zuckermann RN.

Adv Mater. 2015 Oct 14;27(38):5665-91. doi: 10.1002/adma.201500275. Epub 2015 Apr 8.

PMID:
25855478
32.

The Organic Flatland-Recent Advances in Synthetic 2D Organic Layers.

Cai SL, Zhang WG, Zuckermann RN, Li ZT, Zhao X, Liu Y.

Adv Mater. 2015 Oct 14;27(38):5762-70. doi: 10.1002/adma.201500124. Epub 2015 Mar 3.

PMID:
25735971
33.

Structure-determining step in the hierarchical assembly of peptoid nanosheets.

Sanii B, Haxton TK, Olivier GK, Cho A, Barton B, Proulx C, Whitelam S, Zuckermann RN.

ACS Nano. 2014 Nov 25;8(11):11674-84. doi: 10.1021/nn505007u. Epub 2014 Oct 24.

PMID:
25327498
34.

Morphology-conductivity relationship in crystalline and amorphous sequence-defined peptoid block copolymer electrolytes.

Sun J, Liao X, Minor AM, Balsara NP, Zuckermann RN.

J Am Chem Soc. 2014 Oct 22;136(42):14990-7. doi: 10.1021/ja5080689. Epub 2014 Oct 9.

PMID:
25251756
35.

Assembly and molecular order of two-dimensional peptoid nanosheets through the oil-water interface.

Robertson EJ, Oliver GK, Qian M, Proulx C, Zuckermann RN, Richmond GL.

Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):13284-9. doi: 10.1073/pnas.1414843111. Epub 2014 Sep 2.

36.

Tuning calcite morphology and growth acceleration by a rational design of highly stable protein-mimetics.

Chen CL, Qi J, Tao J, Zuckermann RN, DeYoreo JJ.

Sci Rep. 2014 Sep 5;4:6266. doi: 10.1038/srep06266.

37.

Matching 4.7-Å XRD spacing in amelogenin nanoribbons and enamel matrix.

Sanii B, Martinez-Avila O, Simpliciano C, Zuckermann RN, Habelitz S.

J Dent Res. 2014 Sep;93(9):918-22. doi: 10.1177/0022034514544216. Epub 2014 Jul 21.

38.

Nanometer-scale siRNA carriers incorporating peptidomimetic oligomers: physical characterization and biological activity.

Konca YU, Kirshenbaum K, Zuckermann RN.

Int J Nanomedicine. 2014 May 10;9:2271-85. doi: 10.2147/IJN.S57449. eCollection 2014.

39.

Crystallization in sequence-defined peptoid diblock copolymers induced by microphase separation.

Sun J, Teran AA, Liao X, Balsara NP, Zuckermann RN.

J Am Chem Soc. 2014 Feb 5;136(5):2070-7. doi: 10.1021/ja412123y. Epub 2014 Jan 27.

PMID:
24422712
40.

Development and use of an atomistic CHARMM-based forcefield for peptoid simulation.

Mirijanian DT, Mannige RV, Zuckermann RN, Whitelam S.

J Comput Chem. 2014 Feb 15;35(5):360-70. doi: 10.1002/jcc.23478. Epub 2013 Nov 29.

PMID:
24293222
41.

Antibody-mimetic peptoid nanosheets for molecular recognition.

Olivier GK, Cho A, Sanii B, Connolly MD, Tran H, Zuckermann RN.

ACS Nano. 2013 Oct 22;7(10):9276-86. doi: 10.1021/nn403899y. Epub 2013 Sep 18.

PMID:
24016337
42.

Nanoscale phase separation in sequence-defined peptoid diblock copolymers.

Sun J, Teran AA, Liao X, Balsara NP, Zuckermann RN.

J Am Chem Soc. 2013 Sep 25;135(38):14119-24. doi: 10.1021/ja404233d. Epub 2013 Sep 16.

43.

Coarse-grained, foldable, physical model of the polypeptide chain.

Chakraborty P, Zuckermann RN.

Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13368-73. doi: 10.1073/pnas.1305741110. Epub 2013 Jul 29.

44.

Peptoid polymers: a highly designable bioinspired material.

Sun J, Zuckermann RN.

ACS Nano. 2013 Jun 25;7(6):4715-32. doi: 10.1021/nn4015714. Epub 2013 May 30.

PMID:
23721608
45.

Synthesis and characterization of designed BMHP1-derived self-assembling peptides for tissue engineering applications.

Silva D, Natalello A, Sanii B, Vasita R, Saracino G, Zuckermann RN, Doglia SM, Gelain F.

Nanoscale. 2013 Jan 21;5(2):704-18. doi: 10.1039/c2nr32656f. Epub 2012 Dec 10.

PMID:
23223865
46.

De novo structure prediction and experimental characterization of folded peptoid oligomers.

Butterfoss GL, Yoo B, Jaworski JN, Chorny I, Dill KA, Zuckermann RN, Bonneau R, Kirshenbaum K, Voelz VA.

Proc Natl Acad Sci U S A. 2012 Sep 4;109(36):14320-5. doi: 10.1073/pnas.1209945109. Epub 2012 Aug 20.

47.

Stabilization of nanoparticles under biological assembly conditions using peptoids.

Robinson DB, Buffleben GM, Langham ME, Zuckermann RN.

Biopolymers. 2011;96(5):669-78.

PMID:
22180912
48.

Folding of a single-chain, information-rich polypeptoid sequence into a highly ordered nanosheet.

Kudirka R, Tran H, Sanii B, Nam KT, Choi PH, Venkateswaran N, Chen R, Whitelam S, Zuckermann RN.

Biopolymers. 2011;96(5):586-95.

PMID:
22180906
49.

Solid-phase submonomer synthesis of peptoid polymers and their self-assembly into highly-ordered nanosheets.

Tran H, Gael SL, Connolly MD, Zuckermann RN.

J Vis Exp. 2011 Nov 2;(57):e3373. doi: 10.3791/3373.

50.

Protein side-chain translocation mutagenesis via incorporation of peptoid residues.

Lee BC, Zuckermann RN.

ACS Chem Biol. 2011 Dec 16;6(12):1367-74. doi: 10.1021/cb200300w. Epub 2011 Oct 13.

PMID:
21958072

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