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Items: 1 to 50 of 208

1.

Tailoring subtractive cell biopanning to identify diffuse gastric adenocarcinoma-associated antigens via human scFv antibodies.

Mehdipour T, Tohidkia MR, Ata Saei A, Kazemi A, Khajeh S, Rahim Rahimi AA, Nikfarjam S, Farhadi M, Halimi M, Soleimani R, Zubarev RA, Nouri M.

Immunology. 2019 Oct 9. doi: 10.1111/imm.13129. [Epub ahead of print]

PMID:
31596953
2.

Proteome Integral Solubility Alteration: A High-Throughput Proteomics Assay for Target Deconvolution.

Gaetani M, Sabatier P, Saei AA, Beusch CM, Yang Z, Lundström SL, Zubarev RA.

J Proteome Res. 2019 Nov 1;18(11):4027-4037. doi: 10.1021/acs.jproteome.9b00500. Epub 2019 Oct 14.

PMID:
31545609
3.

Anticancer Effect of Deuterium Depleted Water - Redox Disbalance Leads to Oxidative Stress.

Zhang X, Gaetani M, Chernobrovkin A, Zubarev RA.

Mol Cell Proteomics. 2019 Dec;18(12):2373-2387. doi: 10.1074/mcp.RA119.001455. Epub 2019 Sep 13.

4.

The Russian Mass Spectrometry Interest Group at ASMS: Over 20 Years of Science and Water Polo.

Tsybin YO, Bondarenko PV, Artaev VB, Zubarev RA, Costello CE.

J Am Soc Mass Spectrom. 2019 Oct;30(10):2178-2182. doi: 10.1007/s13361-019-02281-9. Epub 2019 Aug 7.

PMID:
31392702
5.

Oxidative Stress Induced by the Deubiquitinase Inhibitor b-AP15 Is Associated with Mitochondrial Impairment.

Zhang X, Espinosa B, Saei AA, D'Arcy P, Zubarev RA, Linder S.

Oxid Med Cell Longev. 2019 Jun 10;2019:1659468. doi: 10.1155/2019/1659468. eCollection 2019.

6.

SpotLight Proteomics-A IgG-Enrichment Phenotype Profiling Approach with Clinical Implications.

Lundström SL, Heyder T, Wiklundh E, Zhang B, Eklund A, Grunewald J, Zubarev RA.

Int J Mol Sci. 2019 May 1;20(9). pii: E2157. doi: 10.3390/ijms20092157.

7.

Posttranslational Targeting of a Recombinant Protein Promotes Its Efficient Secretion into the Escherichia coli Periplasm.

Ytterberg AJ, Zubarev RA, Baumgarten T.

Appl Environ Microbiol. 2019 Jun 17;85(13). pii: e00671-19. doi: 10.1128/AEM.00671-19. Print 2019 Jul 1.

8.

Repurposing of auranofin: Thioredoxin reductase remains a primary target of the drug.

Zhang X, Selvaraju K, Saei AA, D'Arcy P, Zubarev RA, Arnér ES, Linder S.

Biochimie. 2019 Jul;162:46-54. doi: 10.1016/j.biochi.2019.03.015. Epub 2019 Apr 1.

PMID:
30946948
9.

Brain Proteome of Drosophila melanogaster Is Enriched with Nuclear Proteins.

Kuznetsova KG, Ivanov MV, Pyatnitskiy MA, Levitsky LI, Ilina IY, Chernobrovkin AL, Zubarev RA, Gorhskov MV, Moshkovskii SA.

Biochemistry (Mosc). 2019 Jan;84(1):71-78. doi: 10.1134/S0006297919010097.

10.

Proteomic Analysis of Mouse Brain Subjected to Spaceflight.

Mao XW, Sandberg LB, Gridley DS, Herrmann EC, Zhang G, Raghavan R, Zubarev RA, Zhang B, Stodieck LS, Ferguson VL, Bateman TA, Pecaut MJ.

Int J Mol Sci. 2018 Dec 20;20(1). pii: E7. doi: 10.3390/ijms20010007.

11.

Patients with anti-Jo1 antibodies display a characteristic IgG Fc-glycan profile which is further enhanced in anti-Jo1 autoantibodies.

Fernandes-Cerqueira C, Renard N, Notarnicola A, Wigren E, Gräslund S, Zubarev RA, Lundberg IE, Lundström SL.

Sci Rep. 2018 Dec 18;8(1):17958. doi: 10.1038/s41598-018-36395-z.

12.

Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation.

Visnes T, Cázares-Körner A, Hao W, Wallner O, Masuyer G, Loseva O, Mortusewicz O, Wiita E, Sarno A, Manoilov A, Astorga-Wells J, Jemth AS, Pan L, Sanjiv K, Karsten S, Gokturk C, Grube M, Homan EJ, Hanna BMF, Paulin CBJ, Pham T, Rasti A, Berglund UW, von Nicolai C, Benitez-Buelga C, Koolmeister T, Ivanic D, Iliev P, Scobie M, Krokan HE, Baranczewski P, Artursson P, Altun M, Jensen AJ, Kalderén C, Ba X, Zubarev RA, Stenmark P, Boldogh I, Helleday T.

Science. 2018 Nov 16;362(6416):834-839. doi: 10.1126/science.aar8048.

13.

Isotopic resonance at 370 ppm deuterium negatively affects kinetics of luciferin oxidation by luciferase.

Rodin S, Rebellato P, Lundin A, Zubarev RA.

Sci Rep. 2018 Nov 2;8(1):16249. doi: 10.1038/s41598-018-34704-0.

14.

Dynamic Proteomics Reveals High Plasticity of Cellular Proteome: Growth-Related and Drug-Induced Changes in Cancer Cells are Comparable.

Sabatier P, Saei AA, Wang S, Zubarev RA.

Proteomics. 2018 Dec;18(24):e1800118. doi: 10.1002/pmic.201800118. Epub 2018 Nov 30.

PMID:
30382632
15.

Proteogenomics of Adenosine-to-Inosine RNA Editing in the Fruit Fly.

Kuznetsova KG, Kliuchnikova AA, Ilina IU, Chernobrovkin AL, Novikova SE, Farafonova TE, Karpov DS, Ivanov MV, Goncharov AO, Ilgisonis EV, Voronko OE, Nasaev SS, Zgoda VG, Zubarev RA, Gorshkov MV, Moshkovskii SA.

J Proteome Res. 2018 Nov 2;17(11):3889-3903. doi: 10.1021/acs.jproteome.8b00553. Epub 2018 Oct 17.

PMID:
30298734
16.

Structural Basis of Cross-Reactivity of Anti-Citrullinated Protein Antibodies.

Ge C, Xu B, Liang B, Lönnblom E, Lundström SL, Zubarev RA, Ayoglu B, Nilsson P, Skogh T, Kastbom A, Malmström V, Klareskog L, Toes REM, Rispens T, Dobritzsch D, Holmdahl R.

Arthritis Rheumatol. 2019 Feb;71(2):210-221. doi: 10.1002/art.40698. Epub 2019 Jan 4.

PMID:
30152126
17.

Pharmacoproteomics Profiling of Plasma From β-Thalassemia Patients in Response to Hydroxyurea Treatment.

Zohaib M, Ansari SH, Shamsi TS, Zubarev RA, Zarina S.

J Clin Pharmacol. 2019 Jan;59(1):98-106. doi: 10.1002/jcph.1297. Epub 2018 Aug 27.

PMID:
30152032
18.

The deubiquitinase inhibitor b-AP15 induces strong proteotoxic stress and mitochondrial damage.

Zhang X, Pellegrini P, Saei AA, Hillert EK, Mazurkiewicz M, Olofsson MH, Zubarev RA, D'Arcy P, Linder S.

Biochem Pharmacol. 2018 Oct;156:291-301. doi: 10.1016/j.bcp.2018.08.039. Epub 2018 Aug 25.

PMID:
30149015
19.

Biology/Disease-Driven Initiative on Protein-Aggregation Diseases of the Human Proteome Project: Goals and Progress to Date.

Boersema PJ, Melnik A, Hazenberg BPC, Rezeli M, Marko-Varga G, Kamiie J, Portelius E, Blennow K, Zubarev RA, Polymenidou M, Picotti P.

J Proteome Res. 2018 Dec 7;17(12):4072-4084. doi: 10.1021/acs.jproteome.8b00401. Epub 2018 Sep 28. Review.

PMID:
30137990
20.

STAT3 differential scanning fluorimetry and differential scanning light scattering assays: Addressing a missing link in the characterization of STAT3 inhibitor interactions.

Desroses M, Busker S, Astorga-Wells J, Attarha S, Kolosenko I, Zubarev RA, Helleday T, Grandér D, Page BDG.

J Pharm Biomed Anal. 2018 Oct 25;160:80-88. doi: 10.1016/j.jpba.2018.07.018. Epub 2018 Jul 17.

21.

Altered Fc galactosylation in IgG4 is a potential serum marker for chronic lung disease.

Heyder T, Wiklundh E, Eklund A, James A, Grunewald J, Zubarev RA, Lundström SL.

ERJ Open Res. 2018 Jul 31;4(3). pii: 00033-2018. doi: 10.1183/23120541.00033-2018. eCollection 2018 Jul.

22.

Streptococcal Endo-β-N-Acetylglucosaminidase Suppresses Antibody-Mediated Inflammation In Vivo.

Nandakumar KS, Collin M, Happonen KE, Lundström SL, Croxford AM, Xu B, Zubarev RA, Rowley MJ, Blom AM, Kjellman C, Holmdahl R.

Front Immunol. 2018 Jul 16;9:1623. doi: 10.3389/fimmu.2018.01623. eCollection 2018.

23.

Proteomic Identification of Heat Shock-Induced Danger Signals in a Melanoma Cell Lysate Used in Dendritic Cell-Based Cancer Immunotherapy.

González FE, Chernobrovkin A, Pereda C, García-Salum T, Tittarelli A, López MN, Salazar-Onfray F, Zubarev RA.

J Immunol Res. 2018 Mar 18;2018:3982942. doi: 10.1155/2018/3982942. eCollection 2018.

24.

Optimizing Recombinant Protein Production in the Escherichia coli Periplasm Alleviates Stress.

Baumgarten T, Ytterberg AJ, Zubarev RA, de Gier JW.

Appl Environ Microbiol. 2018 May 31;84(12). pii: e00270-18. doi: 10.1128/AEM.00270-18. Print 2018 Jun 15.

25.

Proteogenomics of Malignant Melanoma Cell Lines: The Effect of Stringency of Exome Data Filtering on Variant Peptide Identification in Shotgun Proteomics.

Lobas AA, Pyatnitskiy MA, Chernobrovkin AL, Ilina IY, Karpov DS, Solovyeva EM, Kuznetsova KG, Ivanov MV, Lyssuk EY, Kliuchnikova AA, Voronko OE, Larin SS, Zubarev RA, Gorshkov MV, Moshkovskii SA.

J Proteome Res. 2018 May 4;17(5):1801-1811. doi: 10.1021/acs.jproteome.7b00841. Epub 2018 Apr 16.

PMID:
29619825
26.

Comparative Proteomics of Dying and Surviving Cancer Cells Improves the Identification of Drug Targets and Sheds Light on Cell Life/Death Decisions.

Saei AA, Sabatier P, Tokat ÜG, Chernobrovkin A, Pirmoradian M, Zubarev RA.

Mol Cell Proteomics. 2018 Jun;17(6):1144-1155. doi: 10.1074/mcp.RA118.000610. Epub 2018 Mar 23.

27.

Variable domain N-linked glycosylation and negative surface charge are key features of monoclonal ACPA: Implications for B-cell selection.

Lloyd KA, Steen J, Amara K, Titcombe PJ, Israelsson L, Lundström SL, Zhou D, Zubarev RA, Reed E, Piccoli L, Gabay C, Lanzavecchia A, Baeten D, Lundberg K, Mueller DL, Klareskog L, Malmström V, Grönwall C.

Eur J Immunol. 2018 Jun;48(6):1030-1045. doi: 10.1002/eji.201747446. Epub 2018 Apr 6.

28.

Size-Dependent Hydrogen Atom Attachment to Gas-Phase Hydrogen-Deficient Polypeptide Radical Cations.

Di Stefano LH, Papanastasiou D, Zubarev RA.

J Am Chem Soc. 2018 Jan 17;140(2):531-533. doi: 10.1021/jacs.7b10318. Epub 2018 Jan 4.

PMID:
29292649
29.

Identification and characterization of antibodies elicited by human cystatin C fragment.

Behrendt I, Prądzińska M, Spodzieja M, Czaplewska P, Kołodziejczyk AS, Szymańska A, Kasprzykowski F, Lundström SL, Zubarev RA, Rodziewicz-Motowidło S.

J Mol Recognit. 2018 Apr;31(4). doi: 10.1002/jmr.2689. Epub 2017 Dec 5.

PMID:
29205549
30.

IgM antibodies against phosphorylcholine promote polarization of T regulatory cells from patients with atherosclerotic plaques, systemic lupus erythematosus and healthy donors.

Sun J, Lundström SL, Zhang B, Zubarev RA, Steuer J, Gillgren P, Rahman M, Ajeganova S, Liu A, Frostegård J.

Atherosclerosis. 2018 Jan;268:36-48. doi: 10.1016/j.atherosclerosis.2017.11.010. Epub 2017 Nov 16.

PMID:
29175653
31.

Corrigendum: Functional and Structural Characterization of a Novel HLA-DRB1*04:01-Restricted α-Enolase T Cell Epitope in Rheumatoid Arthritis.

Gerstner C, Dubnovitsky A, Sandin C, Kozhukh G, Uchtenhagen H, James EA, Rönnelid J, Ytterberg AJ, Pieper J, Reed E, Tandre K, Rieck M, Zubarev RA, Rönnblom L, Sandalova T, Buckner JH, Achour A, Malmström V.

Front Immunol. 2017 Oct 4;8:1236. doi: 10.3389/fimmu.2017.01236. eCollection 2017.

32.

The SysteMHC Atlas project.

Shao W, Pedrioli PGA, Wolski W, Scurtescu C, Schmid E, Vizcaíno JA, Courcelles M, Schuster H, Kowalewski D, Marino F, Arlehamn CSL, Vaughan K, Peters B, Sette A, Ottenhoff THM, Meijgaarden KE, Nieuwenhuizen N, Kaufmann SHE, Schlapbach R, Castle JC, Nesvizhskii AI, Nielsen M, Deutsch EW, Campbell DS, Moritz RL, Zubarev RA, Ytterberg AJ, Purcell AW, Marcilla M, Paradela A, Wang Q, Costello CE, Ternette N, van Veelen PA, van Els CACM, Heck AJR, de Souza GA, Sollid LM, Admon A, Stevanovic S, Rammensee HG, Thibault P, Perreault C, Bassani-Sternberg M, Aebersold R, Caron E.

Nucleic Acids Res. 2018 Jan 4;46(D1):D1237-D1247. doi: 10.1093/nar/gkx664.

33.

IgG Fc galactosylation predicts response to methotrexate in early rheumatoid arthritis.

Lundström SL, Hensvold AH, Rutishauser D, Klareskog L, Ytterberg AJ, Zubarev RA, Catrina AI.

Arthritis Res Ther. 2017 Aug 9;19(1):182. doi: 10.1186/s13075-017-1389-7.

34.

Autoreactivity to malondialdehyde-modifications in rheumatoid arthritis is linked to disease activity and synovial pathogenesis.

Grönwall C, Amara K, Hardt U, Krishnamurthy A, Steen J, Engström M, Sun M, Ytterberg AJ, Zubarev RA, Scheel-Toellner D, Greenberg JD, Klareskog L, Catrina AI, Malmström V, Silverman GJ.

J Autoimmun. 2017 Nov;84:29-45. doi: 10.1016/j.jaut.2017.06.004. Epub 2017 Jun 21.

PMID:
28647488
35.

Expression proteomics study to determine metallodrug targets and optimal drug combinations.

Lee RFS, Chernobrovkin A, Rutishauser D, Allardyce CS, Hacker D, Johnsson K, Zubarev RA, Dyson PJ.

Sci Rep. 2017 May 8;7(1):1590. doi: 10.1038/s41598-017-01643-1.

36.

SpotLight Proteomics: uncovering the hidden blood proteome improves diagnostic power of proteomics.

Lundström SL, Zhang B, Rutishauser D, Aarsland D, Zubarev RA.

Sci Rep. 2017 Feb 7;7:41929. doi: 10.1038/srep41929.

37.

On the Effect of Planetary Stable Isotope Compositions on Growth and Survival of Terrestrial Organisms.

Xie X, Zubarev RA.

PLoS One. 2017 Jan 4;12(1):e0169296. doi: 10.1371/journal.pone.0169296. eCollection 2017.

38.

Human IgM Antibodies to Malondialdehyde Conjugated With Albumin Are Negatively Associated With Cardiovascular Disease Among 60-Year-Olds.

Thiagarajan D, Frostegård AG, Singh S, Rahman M, Liu A, Vikström M, Leander K, Gigante B, Hellenius ML, Zhang B, Zubarev RA, de Faire U, Lundström SL, Frostegård J.

J Am Heart Assoc. 2016 Dec 20;5(12). pii: e004415. doi: 10.1161/JAHA.116.004415.

39.

Cytotoxic and Proinflammatory Effects of Metal-Based Nanoparticles on THP-1 Monocytes Characterized by Combined Proteomics Approaches.

Tarasova NK, Gallud A, Ytterberg AJ, Chernobrovkin A, Aranzaes JR, Astruc D, Antipov A, Fedutik Y, Fadeel B, Zubarev RA.

J Proteome Res. 2017 Feb 3;16(2):689-697. doi: 10.1021/acs.jproteome.6b00747. Epub 2016 Dec 28.

PMID:
27973853
40.

Functional and Structural Characterization of a Novel HLA-DRB1*04:01-Restricted α-Enolase T Cell Epitope in Rheumatoid Arthritis.

Gerstner C, Dubnovitsky A, Sandin C, Kozhukh G, Uchtenhagen H, James EA, Rönnelid J, Ytterberg AJ, Pieper J, Reed E, Tandre K, Rieck M, Zubarev RA, Rönnblom L, Sandalova T, Buckner JH, Achour A, Malmström V.

Front Immunol. 2016 Nov 14;7:494. eCollection 2016. Erratum in: Front Immunol. 2017 Oct 04;8:1236.

41.

Validation and development of MTH1 inhibitors for treatment of cancer.

Warpman Berglund U, Sanjiv K, Gad H, Kalderén C, Koolmeister T, Pham T, Gokturk C, Jafari R, Maddalo G, Seashore-Ludlow B, Chernobrovkin A, Manoilov A, Pateras IS, Rasti A, Jemth AS, Almlöf I, Loseva O, Visnes T, Einarsdottir BO, Gaugaz FZ, Saleh A, Platzack B, Wallner OA, Vallin KS, Henriksson M, Wakchaure P, Borhade S, Herr P, Kallberg Y, Baranczewski P, Homan EJ, Wiita E, Nagpal V, Meijer T, Schipper N, Rudd SG, Bräutigam L, Lindqvist A, Filppula A, Lee TC, Artursson P, Nilsson JA, Gorgoulis VG, Lehtiö J, Zubarev RA, Scobie M, Helleday T.

Ann Oncol. 2016 Dec;27(12):2275-2283. doi: 10.1093/annonc/mdw429. Epub 2016 Nov 8.

PMID:
27827301
42.

Application of amide hydrogen/deuterium exchange mass spectrometry for epitope mapping in human cystatin C.

Prądzińska M, Behrendt I, Astorga-Wells J, Manoilov A, Zubarev RA, Kołodziejczyk AS, Rodziewicz-Motowidło S, Czaplewska P.

Amino Acids. 2016 Dec;48(12):2809-2820. Epub 2016 Aug 29.

43.

Isolation and characterization of autoantibodies against human cystatin C.

Prądzińska M, Behrendt I, Spodzieja M, Kołodziejczyk AS, Rodziewicz-Motowidło S, Szymańska A, Lundström SL, Zubarev RA, Macur K, Czaplewska P.

Amino Acids. 2016 Nov;48(11):2501-2518. Epub 2016 Jun 8.

PMID:
27277188
44.

How well can morphology assess cell death modality? A proteomics study.

Chernobrovkin AL, Zubarev RA.

Cell Death Discov. 2016 Oct 3;2:16068. eCollection 2016.

45.

Approach for Identifying Human Leukocyte Antigen (HLA)-DR Bound Peptides from Scarce Clinical Samples.

Heyder T, Kohler M, Tarasova NK, Haag S, Rutishauser D, Rivera NV, Sandin C, Mia S, Malmström V, Wheelock ÅM, Wahlström J, Holmdahl R, Eklund A, Zubarev RA, Grunewald J, Ytterberg AJ.

Mol Cell Proteomics. 2016 Sep;15(9):3017-29. doi: 10.1074/mcp.M116.060764. Epub 2016 Jul 24.

46.

Establishing a Proteomics-Based Monocyte Assay To Assess Differential Innate Immune Activation Responses.

Tarasova NK, Ytterberg AJ, Lundberg K, Zhang XM, Harris RA, Zubarev RA.

J Proteome Res. 2016 Jul 1;15(7):2337-45. doi: 10.1021/acs.jproteome.6b00422. Epub 2016 Jun 3.

PMID:
27223872
47.

DeMix-Q: Quantification-Centered Data Processing Workflow.

Zhang B, Käll L, Zubarev RA.

Mol Cell Proteomics. 2016 Apr;15(4):1467-78. doi: 10.1074/mcp.O115.055475. Epub 2016 Jan 4.

48.

Subset of Kappa and Lambda Germline Sequences Result in Light Chains with a Higher Molecular Mass Phenotype.

Barnidge DR, Lundström SL, Zhang B, Dasari S, Murray DL, Zubarev RA.

J Proteome Res. 2015 Dec 4;14(12):5283-90. doi: 10.1021/acs.jproteome.5b00711. Epub 2015 Nov 24.

PMID:
26598961
49.

Development of autoantibodies against muscle-specific FHL1 in severe inflammatory myopathies.

Albrecht I, Wick C, Hallgren Å, Tjärnlund A, Nagaraju K, Andrade F, Thompson K, Coley W, Phadke A, Diaz-Gallo LM, Bottai M, Nennesmo I, Chemin K, Herrath J, Johansson K, Wikberg A, Ytterberg AJ, Zubarev RA, Danielsson O, Krystufkova O, Vencovsky J, Landegren N, Wahren-Herlenius M, Padyukov L, Kämpe O, Lundberg IE.

J Clin Invest. 2015 Dec;125(12):4612-24. doi: 10.1172/JCI81031. Epub 2015 Nov 9.

50.

Multijunction Capillary Isoelectric Focusing Device Combined with Online Membrane-Assisted Buffer Exchanger Enables Isoelectric Point Fractionation of Intact Human Plasma Proteins for Biomarker Discovery.

Pirmoradian M, Astorga-Wells J, Zubarev RA.

Anal Chem. 2015 Dec 1;87(23):11840-6. doi: 10.1021/acs.analchem.5b03344. Epub 2015 Nov 12.

PMID:
26531800

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