Multiomics atlas-assisted discovery of transcription factors enables specific cell state programming.
Chung HK, Liu C, Sun M, Casillas E, Chen T, Chick B, Wang J, Ma S, Mcdonald B, He P, Yang Q, Varanasi SK, Mann T, Chen D, Hoffmann F, Tripple V, Hang Y, Ho J, Cho UH, Williams A, Wang Y, Hargreaves D, Kaech SM, Wang W.
Chung HK, et al.
bioRxiv [Preprint]. 2023 Dec 5:2023.01.03.522354. doi: 10.1101/2023.01.03.522354.
bioRxiv. 2023.
PMID: 36711632
Free PMC article.
Preprint.
However, Tex (Term) exhibits high similarity with the beneficial tissue-resident memory T states (T (RM) ) in terms of their locations and transcription profiles. Our bioinformatic analysis predicted Zscan20 , a novel TF, to be uniquely active in Tex (Term) . Consistently, …
However, Tex (Term) exhibits high similarity with the beneficial tissue-resident memory T states (T (RM) ) in terms of their locations and t …