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Items: 1 to 50 of 59

1.

Immunomodulatory oligonucleotide IMT504: Effects on mesenchymal stem cells as a first-in-class immunoprotective/immunoregenerative therapy.

Zorzopulos J, Opal SM, Hernando-Insúa A, Rodriguez JM, Elías F, Fló J, López RA, Chasseing NA, Lux-Lantos VA, Coronel MF, Franco R, Montaner AD, Horn DL.

World J Stem Cells. 2017 Mar 26;9(3):45-67. doi: 10.4252/wjsc.v9.i3.45. Review.

2.

PyNTTTTGT and CpG immunostimulatory oligonucleotides: effect on granulocyte/monocyte colony-stimulating factor (GM-CSF) secretion by human CD56+ (NK and NKT) cells.

Rodriguez JM, Marchicio J, López M, Ziblat A, Elias F, Fló J, López RA, Horn D, Zorzopulos J, Montaner AD.

PLoS One. 2015 Feb 23;10(2):e0117484. doi: 10.1371/journal.pone.0117484. eCollection 2015.

3.

The novel immunotherapeutic oligodeoxynucleotide IMT504 protects neutropenic animals from fatal Pseudomonas aeruginosa bacteremia and sepsis.

Chahin A, Opal SM, Zorzopulos J, Jobes DV, Migdady Y, Yamamoto M, Parejo N, Palardy JE, Horn DL.

Antimicrob Agents Chemother. 2015 Feb;59(2):1225-9. doi: 10.1128/AAC.03923-14. Epub 2014 Dec 15.

4.

Non-clinical safety studies of IMT504, a unique non-CpG oligonucleotide.

Franco R, Rodriguez JM, Elías F, Hernando-Insúa A, Fló J, López R, Nagle C, Lago N, Zorzopulos J, Horn DL, Montaner AD.

Nucleic Acid Ther. 2014 Aug;24(4):267-82. doi: 10.1089/nat.2013.0479. Epub 2014 Apr 10.

5.

Addition of the immunostimulatory oligonucleotide IMT504 to a seasonal flu vaccine increases hemagglutinin antibody titers in young adult and elder rats, and expands the anti-hemagglutinin antibody repertoire.

Montaner AD, Denichilo A, Rodríguez JM, Fló J, López RA, Pontoriero A, Savy V, Baumeister E, Frank R, Zorzopulos J, Elías F.

Nucleic Acid Ther. 2011 Aug;21(4):265-74. doi: 10.1089/nat.2011.0284. Epub 2011 Jul 5.

PMID:
21793787
6.

Oligodeoxynucleotide IMT504 induces a marked recovery in a streptozotocin-induced model of diabetes in rats: correlation with an early increase in the expression of nestin and neurogenin 3 progenitor cell markers.

Bianchi MS, Hernando-Insúa A, Chasseing NA, Rodríguez JM, Elías F, Lago N, Zorzopulos J, Libertun C, Montaner AD, Lux-Lantos VA.

Diabetologia. 2010 Jun;53(6):1184-9. doi: 10.1007/s00125-010-1694-z. Epub 2010 Mar 11.

PMID:
20221823
7.

A high dose of IMT504, the PyNTTTTGT prototype immunostimulatory oligonucleotide, does not alter embryonic development in rats.

Hernando-Insúa A, Rodriguez JM, Elías F, Fló J, López R, Franco R, Lago N, Zorzopulos J, Montaner AD.

Oligonucleotides. 2010 Feb;20(1):33-6. doi: 10.1089/oli.2009.0206.

PMID:
19943802
8.

IMT504, the prototype of the immunostimulatory oligonucleotides of the PyNTTTTGT class, increases the number of progenitors of mesenchymal stem cells both in vitro and in vivo: potential use in tissue repair therapy.

Hernando Insúa A, Montaner AD, Rodriguez JM, Elías F, Fló J, López RA, Zorzopulos J, Hofer EL, Chasseing NA.

Stem Cells. 2007 Apr;25(4):1047-54.

9.

Immunostimulatory PyNTTTTGT oligodeoxynucleotides: structural properties and refinement of the active motif.

Rodriguez JM, Elías F, Fló J, López RA, Zorzopulos J, Montaner AD.

Oligonucleotides. 2006 Fall;16(3):275-85.

PMID:
16978090
10.

Oligonucleotide IMT504 induces an immunogenic phenotype and apoptosis in chronic lymphocytic leukemia cells.

Rodriguez JM, Elias F, Montaner A, Flo J, Lopez RA, Zorzopulos J, Franco RJ, Lenial SP, Lopez Salón M, Pirpignani ML, Solimano J, Garay G, Riveros D, Fernandez J, Cacchione R, Dupont J.

Medicina (B Aires). 2006;66(1):9-16.

PMID:
16555722
11.

Vaccine shortage for pandemic influenza: can it be solved?

López RA, Zorzopulos J.

Vaccine. 2006 Apr 5;24(15):2701. Epub 2005 Oct 6. No abstract available.

PMID:
16497415
12.

Readers' and author's responses to the webcast video editorial entitled "pandemic flu: we are not prepared".

López RA, Zorzopulos J.

MedGenMed. 2005;7(2):31; author reply 31. No abstract available.

PMID:
16385705
13.

Ganglioside GM1-binding peptides as adjuvants of antigens inoculated by the intranasal route.

Montaner AD, De Nichilo A, Elias F, Rodríguez JM, Fló JM, López RA, Zorzopulos J, Frank R.

Vaccine. 2006 Mar 10;24(11):1889-96. Epub 2005 Nov 7.

PMID:
16343699
14.

PyNTTTTGT prototype oligonucleotide IMT504 is a potent adjuvant for the recombinant hepatitis B vaccine that enhances the Th1 response.

Elias F, Flo J, Rodriguez JM, De Nichilo A, Lopez RA, Zorzopulos J, Nagle C, Lahoz M, Montaner A.

Vaccine. 2005 May 20;23(27):3597-603.

PMID:
15855019
15.
16.

Birth of the domains Bacteria, Archaea and Eucarya and of major taxa within them: a hypothesis.

Zorzopulos J.

Rev Argent Microbiol. 2003 Oct-Dec;35(4):175-82. Review.

PMID:
14976868
17.

Strong cytosine-guanosine-independent immunostimulation in humans and other primates by synthetic oligodeoxynucleotides with PyNTTTTGT motifs.

Elias F, Flo J, Lopez RA, Zorzopulos J, Montaner A, Rodriguez JM.

J Immunol. 2003 Oct 1;171(7):3697-704.

18.

Aeromonas salmonicida subsp. pectinolytica subsp. nov., a new pectinase-positive subspecies isolated from a heavily polluted river.

Pavan ME, Abbott SL, Zorzópulos J, Janda JM.

Int J Syst Evol Microbiol. 2000 May;50 Pt 3:1119-24.

PMID:
10843053
19.

A plasmid vector for isolation of strong promoters in Escherichia coli.

Carbonelli DL, Corley E, Seigelchifer M, Zorzópulos J.

FEMS Microbiol Lett. 1999 Aug 1;177(1):75-82.

20.

Coprothermobacter platensis sp. nov., a new anaerobic proteolytic thermophilic bacterium isolated from an anaerobic mesophilic sludge.

Etchebehere C, Pavan ME, Zorzópulos J, Soubes M, Muxí L.

Int J Syst Bacteriol. 1998 Oct;48 Pt 4:1297-304.

PMID:
9828430
21.
22.

Binding of nuclear factors to a satellite DNA of retroviral origin with marked differences in copy number among species of the rodent Ctenomys.

Pesce CG, Rossi MS, Muro AF, Reig OA, Zorzópulos J, Kornblihtt AR.

Nucleic Acids Res. 1994 Feb 25;22(4):656-61.

23.

Retroviral-like features in the monomer of the major satellite DNA from the South American rodents of the genus Ctenomys.

Rossi MS, Pesce CG, Reig OA, Kornblihtt AR, Zorzópulos J.

DNA Seq. 1993;3(6):379-81.

PMID:
8219281
24.

Effect of DNA concentration on recombinant plasmid recovery after blunt-end ligation.

Bercovich JA, Grinstein S, Zorzopulos J.

Biotechniques. 1992 Feb;12(2):190, 192-3.

PMID:
1616707
25.

[Genetic identity and molecular biology: the DNA fingerprint].

Corley E, Zorzopulos J.

Medicina (B Aires). 1992;52(5):493-5. Spanish. No abstract available.

PMID:
1340895
26.

A staphylococcal plasmid that replicates and expresses ampicillin, gentamicin and amikacin resistance in Escherichia coli.

Gadaleta P, Kaufman S, Martini P, Zorzópulos J.

FEMS Microbiol Lett. 1991 May 15;64(2-3):147-50.

PMID:
1884975
27.

Efficient expression of a Trypanosoma cruzi antigen in Escherichia coli and Staphylococcus aureus and its rapid purification.

Moreno JI, Seigelchifer M, Zorzópulos J.

World J Microbiol Biotechnol. 1991 May;7(3):316-23. doi: 10.1007/BF00329397.

PMID:
24425018
28.
29.

Treatment of recurrent common warts with one low dose of intralesional natural human leukocyte interferon alpha.

Pueyo S, Criscuolo M, Davidovich C, Zorzópulos J, Pesce A, Díaz A.

J Biol Regul Homeost Agents. 1990 Apr-Jun;4(2):47-50.

PMID:
2260502
30.

A new genome type of adenovirus 3 associated with severe lower acute respiratory infection in children.

Kajon AE, Murtagh P, Garcia Franco S, Freire MC, Weissenbacher MC, Zorzópulos J.

J Med Virol. 1990 Jan;30(1):73-6.

PMID:
2154546
31.

Evidence for a net-like organization of lipopolysaccharide particles in the Escherichia coli outer membrane.

Zorzopulos J, de Long S, Chapman V, Kozloff LM.

FEMS Microbiol Lett. 1989 Oct 1;52(1-2):23-6.

PMID:
2689280
32.

An outbreak of multiply resistant Pseudomonas aeruginosa in a neonatal unit: plasmid pattern analysis.

Garcia DC, Trevisan AR, Botto L, Cervetto M, Sarubbi MA, Zorzópulos J.

J Hosp Infect. 1989 Aug;14(2):99-105.

PMID:
2572641
33.

[Development of molecular probes for the diagnosis of mycobacteria].

Franco R, Ruiz Trevisan A, Zorzopulos J.

Rev Argent Microbiol. 1989 Jul-Dec;21(3-4):146-8. Spanish.

PMID:
2486212
34.

[Molecular biology and clinical use of interferons: making the way].

Díaz A, Zorzopulos J.

Medicina (B Aires). 1989;49(4):391-3. Spanish. No abstract available.

PMID:
2484887
35.

Papillomaviruses in human skin warts and their incidence in an Argentine population.

Corley E, Pueyo S, Goc B, Diaz A, Zorzopulos J.

Diagn Microbiol Infect Dis. 1988 Jun;10(2):93-101.

PMID:
2852087
36.

[Molecular epidemiology of infective agents].

Ruiz Trevisán A, Corley E, Kajon A, Centrón García D, Zorzópulos J.

Medicina (B Aires). 1988;48(2):194-200. Review. Spanish. No abstract available.

PMID:
2906713
37.
38.

Molecular cloning of rotavirus genome.

Crespi M, Sánchez D, Tisminetzky S, Bellinzoni R, Bercovich A, Rossi MS, Corley E, De Mendoza D, Hopp E, Zorzopulos J, et al.

Medicina (B Aires). 1986;46(6):693-7. No abstract available.

PMID:
3041173
39.

Deletions in Klebsiella pneumoniae R plasmids induced by growth in the presence of acridine orange at high temperature.

Zorzópulos J, Trevisán AR, Denoya CD.

Antimicrob Agents Chemother. 1984 May;25(5):659-61.

40.

An outbreak of multiply resistant Staphylococcus aureus in Buenos Aires. Clinical observations and plasmid pattern analysis.

Schugurensky A, Cahn P, Osatnik G, Zorzopulos J, Ruiz Trevisan A, Denoya CD.

Medicina (B Aires). 1984;44(1):8-14. No abstract available.

PMID:
6535911
41.

[Methodology for the preparation and analysis of plasmids from a large number of bacterial strains].

Ruiz Trevisan A, Zorzopulos J, Denoya C.

Rev Argent Microbiol. 1984;16(3):169-76. Spanish. No abstract available.

PMID:
6443831
42.
43.

Distribution of the T4D bacteriophage binding sites on the Escherichia coli B surface.

Zorzopulos J, DeLong S, Chapman V, Archer PG, Kozloff LM.

J Recept Res. 1983;3(4):513-27.

PMID:
6358489
44.

Host receptor site for the short tail fibers of bacteriophage T4D.

Zorzopulos J, Delong S, Chapman V, Kozloff LM.

Virology. 1982 Jul 15;120(1):33-41. No abstract available.

PMID:
7048729
45.

[Interferon: from the alchemy to molecular biology].

Díaz A, Zorzópulos J.

Medicina (B Aires). 1982;42(3):328-30. Spanish. No abstract available.

PMID:
15170958
46.

Structural characteristics of the short-tail fibers of T4 bacteriophage.

Zorzopulos J, DeLong S, Chapman V, Kozloff LM.

J Cell Biochem. 1982;18(3):363-75.

PMID:
7040434
47.

[Manipulation of embryos, cells, nuclei and genes. II. Genetic engineering].

Zorzopulos J, Denoya CD.

Rev Argent Microbiol. 1982 Jan-Mar;14(1):41-76. Review. Spanish. No abstract available.

PMID:
6100999
49.

Polymerization of Escherichia coli bacteriophage T4D short tail fibers into filaments and filament bundles.

Zorzopulos J, DeLong S, Chapman V, Kozloff LM.

Prog Clin Biol Res. 1981;64:343-51.

PMID:
7330052
50.

Boophilus microplus: cattle antienzymes to larval phosphomonoesterases.

Reich CI, Zorzopulos J.

Exp Parasitol. 1980 Oct;50(2):272-7. No abstract available.

PMID:
6250874

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