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Items: 34


Hsp90 and complex birth defects: A plausible mechanism for the interaction of genes and environment.

Zohn IE.

Neurosci Lett. 2020 Jan 18;716:134680. doi: 10.1016/j.neulet.2019.134680. Epub 2019 Dec 9. Review.


Reduced maternal vitamin A status increases the incidence of normal aortic arch variants.

Sugrue KF, Zohn IE.

Genesis. 2019 Nov;57(11-12):e23343. doi: 10.1002/dvg.23343. Epub 2019 Nov 4. No abstract available.


Reduced maternal vitamin A status increases the incidence of normal aortic arch variants.

Sugrue KF, Zohn IE.

Genesis. 2019 Jul;57(7-8):e23326. doi: 10.1002/dvg.23326. Epub 2019 Jul 12. Erratum in: Genesis. 2019 Nov;57(11-12):e23343.


The ubiquitin ligase HECTD1 promotes retinoic acid signaling required for development of the aortic arch.

Sugrue KF, Sarkar AA, Leatherbury L, Zohn IE.

Dis Model Mech. 2019 Jan 11;12(1). pii: dmm036491. doi: 10.1242/dmm.036491.


Mechanism for generation of left isomerism in Ccdc40 mutant embryos.

Sugrue KF, Zohn IE.

PLoS One. 2017 Feb 9;12(2):e0171180. doi: 10.1371/journal.pone.0171180. eCollection 2017.


High levels of iron supplementation prevents neural tube defects in the Fpn1ffe mouse model.

Stokes BA, Sabatino JA, Zohn IE.

Birth Defects Res. 2017 Jan 30;109(2):81-91. doi: 10.1002/bdra.23542.


Supt20 is required for development of the axial skeleton.

Warrier S, Nuwayhid S, Sabatino JA, Sugrue KF, Zohn IE.

Dev Biol. 2017 Jan 15;421(2):245-257. doi: 10.1016/j.ydbio.2016.11.009. Epub 2016 Nov 25.


Prevention of neural tube defects in Lrp2 mutant mouse embryos by folic acid supplementation.

Sabatino JA, Stokes BA, Zohn IE.

Birth Defects Res. 2017 Jan 20;109(1):16-26. doi: 10.1002/bdra.23589.


Abnormal labyrinthine zone in the Hectd1-null placenta.

Sarkar AA, Sabatino JA, Sugrue KF, Zohn IE.

Placenta. 2016 Feb;38:16-23. doi: 10.1016/j.placenta.2015.12.002. Epub 2015 Dec 13.


Hard to swallow: Developmental biological insights into pediatric dysphagia.

LaMantia AS, Moody SA, Maynard TM, Karpinski BA, Zohn IE, Mendelowitz D, Lee NH, Popratiloff A.

Dev Biol. 2016 Jan 15;409(2):329-42. doi: 10.1016/j.ydbio.2015.09.024. Epub 2015 Nov 7. Review.


Hectd1 is required for development of the junctional zone of the placenta.

Sarkar AA, Nuwayhid SJ, Maynard T, Ghandchi F, Hill JT, Lamantia AS, Zohn IE.

Dev Biol. 2014 Aug 15;392(2):368-80. doi: 10.1016/j.ydbio.2014.05.007. Epub 2014 May 20.


Dysphagia and disrupted cranial nerve development in a mouse model of DiGeorge (22q11) deletion syndrome.

Karpinski BA, Maynard TM, Fralish MS, Nuwayhid S, Zohn IE, Moody SA, LaMantia AS.

Dis Model Mech. 2014 Feb;7(2):245-57. doi: 10.1242/dmm.012484. Epub 2013 Dec 19.


An explant assay for assessing cellular behavior of the cranial mesenchyme.

Sarkar AA, Zohn IE.

J Vis Exp. 2013 Jan 20;(71). pii: 4245. doi: 10.3791/4245.


HectD1 E3 ligase modifies adenomatous polyposis coli (APC) with polyubiquitin to promote the APC-axin interaction.

Tran H, Bustos D, Yeh R, Rubinfeld B, Lam C, Shriver S, Zilberleyb I, Lee MW, Phu L, Sarkar AA, Zohn IE, Wertz IE, Kirkpatrick DS, Polakis P.

J Biol Chem. 2013 Feb 8;288(6):3753-67. doi: 10.1074/jbc.M112.415240. Epub 2012 Dec 31.


Does the cranial mesenchyme contribute to neural fold elevation during neurulation?

Zohn IE, Sarkar AA.

Birth Defects Res A Clin Mol Teratol. 2012 Oct;94(10):841-8. doi: 10.1002/bdra.23073. Epub 2012 Sep 3. Review.


Mouse as a model for multifactorial inheritance of neural tube defects.

Zohn IE.

Birth Defects Res C Embryo Today. 2012 Jun;96(2):193-205. doi: 10.1002/bdrc.21011. Review.


Hectd1 regulates intracellular localization and secretion of Hsp90 to control cellular behavior of the cranial mesenchyme.

Sarkar AA, Zohn IE.

J Cell Biol. 2012 Mar 19;196(6):789-800. doi: 10.1083/jcb.201105101.


The coiled-coil domain containing protein CCDC40 is essential for motile cilia function and left-right axis formation.

Becker-Heck A, Zohn IE, Okabe N, Pollock A, Lenhart KB, Sullivan-Brown J, McSheene J, Loges NT, Olbrich H, Haeffner K, Fliegauf M, Horvath J, Reinhardt R, Nielsen KG, Marthin JK, Baktai G, Anderson KV, Geisler R, Niswander L, Omran H, Burdine RD.

Nat Genet. 2011 Jan;43(1):79-84. doi: 10.1038/ng.727. Epub 2010 Dec 5.


The iron exporter ferroportin 1 is essential for development of the mouse embryo, forebrain patterning and neural tube closure.

Mao J, McKean DM, Warrier S, Corbin JG, Niswander L, Zohn IE.

Development. 2010 Sep;137(18):3079-88. doi: 10.1242/dev.048744. Epub 2010 Aug 11.


The visceral yolk sac endoderm provides for absorption of nutrients to the embryo during neurulation.

Zohn IE, Sarkar AA.

Birth Defects Res A Clin Mol Teratol. 2010 Aug;88(8):593-600. doi: 10.1002/bdra.20705. Review.


Modeling neural tube defects in the mouse.

Zohn IE, Sarkar AA.

Curr Top Dev Biol. 2008;84:1-35. doi: 10.1016/S0070-2153(08)00601-7. Review.


The Hectd1 ubiquitin ligase is required for development of the head mesenchyme and neural tube closure.

Zohn IE, Anderson KV, Niswander L.

Dev Biol. 2007 Jun 1;306(1):208-21. Epub 2007 Mar 20.


The flatiron mutation in mouse ferroportin acts as a dominant negative to cause ferroportin disease.

Zohn IE, De Domenico I, Pollock A, Ward DM, Goodman JF, Liang X, Sanchez AJ, Niswander L, Kaplan J.

Blood. 2007 May 15;109(10):4174-80. Epub 2007 Feb 8.


p38 and a p38-interacting protein are critical for downregulation of E-cadherin during mouse gastrulation.

Zohn IE, Li Y, Skolnik EY, Anderson KV, Han J, Niswander L.

Cell. 2006 Jun 2;125(5):957-69.


Using genomewide mutagenesis screens to identify the genes required for neural tube closure in the mouse.

Zohn IE, Anderson KV, Niswander L.

Birth Defects Res A Clin Mol Teratol. 2005 Sep;73(9):583-90. Review.


Cell polarity pathways converge and extend to regulate neural tube closure.

Zohn IE, Chesnutt CR, Niswander L.

Trends Cell Biol. 2003 Sep;13(9):451-4. Review.


Rho GTPase-dependent transformation by G protein-coupled receptors.

Whitehead IP, Zohn IE, Der CJ.

Oncogene. 2001 Mar 26;20(13):1547-55. Review.


G2A is an oncogenic G protein-coupled receptor.

Zohn IE, Klinger M, Karp X, Kirk H, Symons M, Chrzanowska-Wodnicka M, Der CJ, Kay RJ.

Oncogene. 2000 Aug 10;19(34):3866-77.


TC21 and Ras share indistinguishable transforming and differentiating activities.

Graham SM, Oldham SM, Martin CB, Drugan JK, Zohn IE, Campbell S, Der CJ.

Oncogene. 1999 Mar 25;18(12):2107-16.


Mas oncogene signaling and transformation require the small GTP-binding protein Rac.

Zohn IE, Symons M, Chrzanowska-Wodnicka M, Westwick JK, Der CJ.

Mol Cell Biol. 1998 Mar;18(3):1225-35.


Angiotensin II stimulates calcium-dependent activation of c-Jun N-terminal kinase.

Zohn IE, Yu H, Li X, Cox AD, Earp HS.

Mol Cell Biol. 1995 Nov;15(11):6160-8.


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