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Items: 1 to 50 of 82

1.

Salvindolin elicits opioid system-mediated antinociceptive and antidepressant-like activities.

Keasling AW, Pandey P, Doerksen RJ, Pedrino GR, Costa EA, da Cunha LC, Zjawiony JK, Fajemiroye JO.

J Psychopharmacol. 2019 Jul;33(7):865-881. doi: 10.1177/0269881119849821. Epub 2019 Jun 13.

PMID:
31192780
2.

Cutting-Edge Search for Safer Opioid Pain Relief: Retrospective Review of Salvinorin A and Its Analogs.

Zjawiony JK, Machado AS, Menegatti R, Ghedini PC, Costa EA, Pedrino GR, Lukas SE, Franco OL, Silva ON, Fajemiroye JO.

Front Psychiatry. 2019 Mar 27;10:157. doi: 10.3389/fpsyt.2019.00157. eCollection 2019. Review.

3.

Therapeutic potential of mistletoe in CNS-related neurological disorders and the chemical composition of Viscum species.

Szurpnicka A, Zjawiony JK, Szterk A.

J Ethnopharmacol. 2019 Mar 1;231:241-252. doi: 10.1016/j.jep.2018.11.025. Epub 2018 Nov 17. Review.

PMID:
30458281
4.

LC-MS-Guided Isolation of Insulin-Secretion-Promoting Monoterpenoid Carbazole Alkaloids from Murraya microphylla.

Ma XL, Li J, Zheng J, Gu XP, Ferreira D, Zjawiony JK, Zhao MB, Guo XY, Tu PF, Jiang Y.

J Nat Prod. 2018 Nov 26;81(11):2371-2380. doi: 10.1021/acs.jnatprod.8b00338. Epub 2018 Nov 1.

PMID:
30381950
5.

ANTIFUNGAL ACTIVITY OF THE ROOT EXTRACTS OF PULSATILLA PATENS AGAINST CANDIDA GLABRATA.

Laskai G, Sienkiewicz A, Zjawiony JK, Jacob M, Khan S.

Acta Pol Pharm. 2017 Jan;74(1):179-185.

6.

Anti-inflammatory Dimeric 2-(2-Phenylethyl)chromones from the Resinous Wood of Aquilaria sinensis.

Huo HX, Zhu ZX, Song YL, Shi SP, Sun J, Sun H, Zhao YF, Zheng J, Ferreira D, Zjawiony JK, Tu PF, Li J.

J Nat Prod. 2018 Mar 23;81(3):543-553. doi: 10.1021/acs.jnatprod.7b00919. Epub 2017 Dec 11.

PMID:
29227647
7.

Preclinical Assessment of Cardiovascular Alterations Induced by Birch Polypore Mushroom, Piptoporus betulinus (Agaricomycetes).

Fajemiroye JO, Mourão AA, Marques SM, Oliveira LP, Neto JRO, Elusiyan AC, Pedrino GR, Costa EA, da Cunha LC, Zjawiony JK.

Int J Med Mushrooms. 2017;19(3):257-265. doi: 10.1615/IntJMedMushrooms.v19.i3.80.

PMID:
28605341
8.

22-azidosalvinorin A exhibits antidepressant-like effect in mice.

Fajemiroye JO, Prabhakar PR, Cunha LC, Costa EA, Zjawiony JK.

Eur J Pharmacol. 2017 Apr 5;800:96-106. doi: 10.1016/j.ejphar.2017.02.031. Epub 2017 Feb 17.

PMID:
28219707
9.

Salvinorin A Inhibits Airway Hyperreactivity Induced by Ovalbumin Sensitization.

Rossi A, Caiazzo E, Bilancia R, Riemma MA, Pagano E, Cicala C, Ialenti A, Zjawiony JK, Izzo AA, Capasso R, Roviezzo F.

Front Pharmacol. 2017 Jan 13;7:525. doi: 10.3389/fphar.2016.00525. eCollection 2016.

10.

Phellinus igniarius: A Pharmacologically Active Polypore Mushroom.

Zapora E, Wolkowycki M, Bakier S, Zjawiony JK.

Nat Prod Commun. 2016 Jul;11(7):1043-1046.

PMID:
30452190
11.

Nitric Oxide Inhibitory Meroterpenoids from the Fungus Penicillium purpurogenum MHZ 111.

Sun J, Zhu ZX, Song YL, Dong D, Zheng J, Liu T, Zhao YF, Ferreira D, Zjawiony JK, Tu PF, Li J.

J Nat Prod. 2016 May 27;79(5):1415-22. doi: 10.1021/acs.jnatprod.6b00160. Epub 2016 Apr 27.

PMID:
27120704
12.

The hallucinogenic diterpene salvinorin A inhibits leukotriene synthesis in experimental models of inflammation.

Rossi A, Pace S, Tedesco F, Pagano E, Guerra G, Troisi F, Werner M, Roviezzo F, Zjawiony JK, Werz O, Izzo AA, Capasso R.

Pharmacol Res. 2016 Apr;106:64-71. doi: 10.1016/j.phrs.2016.01.032. Epub 2016 Feb 6.

PMID:
26859523
13.

Nitric Oxide Inhibitory Dimeric Sesquiterpenoids from Artemisia rupestris.

Zhang C, Wang S, Zeng KW, Li J, Ferreira D, Zjawiony JK, Liu BY, Guo XY, Jin HW, Jiang Y, Tu PF.

J Nat Prod. 2016 Jan 22;79(1):213-23. doi: 10.1021/acs.jnatprod.5b00894. Epub 2015 Dec 22.

PMID:
26696523
14.

IDENTIFICATION CHALLENGES IN EXAMINATION OF COMMERCIAL PLANT MATERIAL OF PSYCHOTRIA VIRIDIS.

Kowalczuk AP, Łozak A, Bachliński R, Duszyński A, Sakowska J, Zjawiony JK.

Acta Pol Pharm. 2015 Jul-Aug;72(4):747-55.

15.

APPLICATION OF CHEMOMETRICS FOR IDENTIFICATION OF PSYCHOACTIVE PLANTS.

Kowalczuk AP, Łozak A, Kiljan M, Mętrak K, Zjawiony JK.

Acta Pol Pharm. 2015 May-Jun;72(3):517-25.

16.

Anti-inflammatory Labdane Diterpenoids from Leonurus macranthus.

Huang Z, Zhu ZX, Li YT, Pang DR, Zheng J, Zhang Q, Zhao YF, Ferreira D, Zjawiony JK, Tu PF, Li J.

J Nat Prod. 2015 Sep 25;78(9):2276-85. doi: 10.1021/acs.jnatprod.5b00635. Epub 2015 Sep 8.

PMID:
26348503
17.

Oleanolic acid acrylate elicits antidepressant-like effect mediated by 5-HT1A receptor.

Fajemiroye JO, Polepally PR, Chaurasiya ND, Tekwani BL, Zjawiony JK, Costa EA.

Sci Rep. 2015 Jul 22;5:11582. doi: 10.1038/srep11582.

18.

Effect of Non-psychotropic Plant-derived Cannabinoids on Bladder Contractility: Focus on Cannabigerol.

Pagano E, Montanaro V, Di Girolamo A, Pistone A, Altieri V, Zjawiony JK, Izzo AA, Capasso R.

Nat Prod Commun. 2015 Jun;10(6):1009-12.

PMID:
26197538
19.

Salvinorin A analogues PR-37 and PR-38 attenuate compound 48/80-induced itch responses in mice.

Salaga M, Polepally PR, Zielinska M, Marynowski M, Fabisiak A, Murawska N, Sobczak K, Sacharczuk M, Do Rego JC, Roth BL, Zjawiony JK, Fichna J.

Br J Pharmacol. 2015 Sep;172(17):4331-41. doi: 10.1111/bph.13212. Epub 2015 Jul 14.

20.

Anti-inflammatory coumarin and benzocoumarin derivatives from Murraya alata.

Lv HN, Wang S, Zeng KW, Li J, Guo XY, Ferreira D, Zjawiony JK, Tu PF, Jiang Y.

J Nat Prod. 2015 Feb 27;78(2):279-85. doi: 10.1021/np500861u. Epub 2015 Jan 26.

PMID:
25621853
21.

Novel activities of CYP11A1 and their potential physiological significance.

Slominski AT, Li W, Kim TK, Semak I, Wang J, Zjawiony JK, Tuckey RC.

J Steroid Biochem Mol Biol. 2015 Jul;151:25-37. doi: 10.1016/j.jsbmb.2014.11.010. Epub 2014 Nov 13. Review.

22.

The G protein-biased κ-opioid receptor agonist RB-64 is analgesic with a unique spectrum of activities in vivo.

White KL, Robinson JE, Zhu H, DiBerto JF, Polepally PR, Zjawiony JK, Nichols DE, Malanga CJ, Roth BL.

J Pharmacol Exp Ther. 2015 Jan;352(1):98-109. doi: 10.1124/jpet.114.216820. Epub 2014 Oct 15.

23.

Novel orally available salvinorin A analog PR-38 protects against experimental colitis and reduces abdominal pain in mice by interaction with opioid and cannabinoid receptors.

Sałaga M, Polepally PR, Zakrzewski PK, Cygankiewicz A, Sobczak M, Kordek R, Zjawiony JK, Krajewska WM, Fichna J.

Biochem Pharmacol. 2014 Dec 15;92(4):618-26. doi: 10.1016/j.bcp.2014.09.018. Epub 2014 Oct 6.

PMID:
25265540
24.

Anti-inflammatory ursane- and oleanane-type triterpenoids from Vitex negundo var. cannabifolia.

Li MM, Su XQ, Sun J, Gu YF, Huang Z, Zeng KW, Zhang Q, Zhao YF, Ferreira D, Zjawiony JK, Li J, Tu PF.

J Nat Prod. 2014 Oct 24;77(10):2248-54. doi: 10.1021/np500509q. Epub 2014 Sep 23.

PMID:
25245917
25.

Michael acceptor approach to the design of new salvinorin A-based high affinity ligands for the kappa-opioid receptor.

Polepally PR, Huben K, Vardy E, Setola V, Mosier PD, Roth BL, Zjawiony JK.

Eur J Med Chem. 2014 Oct 6;85:818-29. doi: 10.1016/j.ejmech.2014.07.077. Epub 2014 Aug 23.

26.

Hypotensive and antihypertensive potential of 4-[(1-phenyl-1H-pyrazol-4-yl) methyl]1-piperazine carboxylic acid ethyl ester: a piperazine derivative.

Fajemiroye JO, Amaral NO, da Silva EF, Galdino PM, de Oliveira TS, Ghedini PC, Zjawiony JK, Costa EA, Pedrino GR, Menegatti R.

Life Sci. 2014 Sep 1;112(1-2):90-6. doi: 10.1016/j.lfs.2014.07.025. Epub 2014 Jul 26.

PMID:
25072354
27.

Anxiolytic and antidepressant like effects of natural food flavour (E)-methyl isoeugenol.

Fajemiroye JO, Galdino PM, De Paula JA, Rocha FF, Akanmu MA, Vanderlinde FA, Zjawiony JK, Costa EA.

Food Funct. 2014 Aug;5(8):1819-28. doi: 10.1039/c4fo00109e.

PMID:
24920211
28.

Plurality of anxiety and depression alteration mechanism by oleanolic acid.

Fajemiroye JO, Galdino PM, Florentino IF, Da Rocha FF, Ghedini PC, Polepally PR, Zjawiony JK, Costa EA.

J Psychopharmacol. 2014 Oct;28(10):923-34. doi: 10.1177/0269881114536789. Epub 2014 Jun 11.

PMID:
24920136
29.

Novel orally available salvinorin A analog PR-38 inhibits gastrointestinal motility and reduces abdominal pain in mouse models mimicking irritable bowel syndrome.

Sałaga M, Polepally PR, Sobczak M, Grzywacz D, Kamysz W, Sibaev A, Storr M, Do Rego JC, Zjawiony JK, Fichna J.

J Pharmacol Exp Ther. 2014 Jul;350(1):69-78. doi: 10.1124/jpet.114.214239.

PMID:
24891526
30.

Anti-inflammatory labdane diterpenoids from Lagopsis supina.

Li H, Li MM, Su XQ, Sun J, Gu YF, Zeng KW, Zhang Q, Zhao YF, Ferreira D, Zjawiony JK, Li J, Tu PF.

J Nat Prod. 2014 Apr 25;77(4):1047-53. doi: 10.1021/np5001329. Epub 2014 Apr 8.

PMID:
24707938
31.

Novel vitamin D photoproducts and their precursors in the skin.

Slominski A, Kim TK, Zmijewski MA, Janjetovic Z, Li W, Chen J, Kusniatsova EI, Semak I, Postlethwaite A, Miller DD, Zjawiony JK, Tuckey RC.

Dermatoendocrinol. 2013 Jan 1;5(1):7-19. doi: 10.4161/derm.23938. Review.

32.

Two new dihydroamentoflavone glycosides from Cycas revoluta.

Moawad A, Hetta M, Zjawiony JK, Ferreira D, Hifnawy M.

Nat Prod Res. 2014;28(1):41-7. doi: 10.1080/14786419.2013.832675. Epub 2013 Sep 9.

PMID:
24404954
33.

Comprehensive methodology for identification of Kratom in police laboratories.

Kowalczuk AP, Łozak A, Zjawiony JK.

Forensic Sci Int. 2013 Dec 10;233(1-3):238-43. doi: 10.1016/j.forsciint.2013.09.016. Epub 2013 Sep 27.

PMID:
24314525
34.

The effect of Salvia divinorum and Mitragyna speciosa extracts, fraction and major constituents on place aversion and place preference in rats.

Sufka KJ, Loria MJ, Lewellyn K, Zjawiony JK, Ali Z, Abe N, Khan IA.

J Ethnopharmacol. 2014;151(1):361-4. doi: 10.1016/j.jep.2013.10.059. Epub 2013 Nov 7.

PMID:
24212071
35.

Identification of novel functionally selective κ-opioid receptor scaffolds.

White KL, Scopton AP, Rives ML, Bikbulatov RV, Polepally PR, Brown PJ, Kenakin T, Javitch JA, Zjawiony JK, Roth BL.

Mol Pharmacol. 2014 Jan;85(1):83-90. doi: 10.1124/mol.113.089649. Epub 2013 Oct 10.

36.

In vitro structure-activity relationships of aplysinopsin analogs and their in vivo evaluation in the chick anxiety-depression model.

Lewellyn K, Bialonska D, Loria MJ, White SW, Sufka KJ, Zjawiony JK.

Bioorg Med Chem. 2013 Nov 15;21(22):7083-90. doi: 10.1016/j.bmc.2013.09.011. Epub 2013 Sep 15.

PMID:
24084296
37.

Vegetative anatomy and micromorphology of Salvia divinorum (Lamiaceae) from Mexico, combined with chromatographic analysis of salvinorin A.

Kowalczuk AP, Raman V, Galal AM, Khan IA, Siebert DJ, Zjawiony JK.

J Nat Med. 2014 Jan;68(1):63-73. doi: 10.1007/s11418-013-0769-9. Epub 2013 Apr 21.

PMID:
23604975
38.

Kappa-opioid receptor-selective dicarboxylic ester-derived salvinorin A ligands.

Polepally PR, White K, Vardy E, Roth BL, Ferreira D, Zjawiony JK.

Bioorg Med Chem Lett. 2013 May 15;23(10):2860-2. doi: 10.1016/j.bmcl.2013.03.111. Epub 2013 Apr 4.

39.

Triterpenoids and flavonoids from Cecropia schreberiana Miq. (Urticaceae).

Li J, Coleman CM, Wu H, Burandt CL Jr, Ferreira D, Zjawiony JK.

Biochem Syst Ecol. 2013 Jun 1;48:96-99. Epub 2013 Jan 16.

40.

Salvinorin A reduces mechanical allodynia and spinal neuronal hyperexcitability induced by peripheral formalin injection.

Guida F, Luongo L, Aviello G, Palazzo E, De Chiaro M, Gatta L, Boccella S, Marabese I, Zjawiony JK, Capasso R, Izzo AA, de Novellis V, Maione S.

Mol Pain. 2012 Aug 23;8:60. doi: 10.1186/1744-8069-8-60.

41.

Synthesis and evaluation of aplysinopsin analogs as inhibitors of human monoamine oxidase A and B.

Lewellyn K, Bialonska D, Chaurasiya ND, Tekwani BL, Zjawiony JK.

Bioorg Med Chem Lett. 2012 Aug 1;22(15):4926-9. doi: 10.1016/j.bmcl.2012.06.058. Epub 2012 Jun 23.

PMID:
22781190
42.

Bis-spirolabdane diterpenoids from Leonotis nepetaefolia.

Li J, Fronczek FR, Ferreira D, Burandt CL Jr, Setola V, Roth BL, Zjawiony JK.

J Nat Prod. 2012 Apr 27;75(4):728-34. doi: 10.1021/np3000156. Epub 2012 Apr 4.

43.

Labdane diterpenoids from Leonotis leonurus.

Wu H, Li J, Fronczek FR, Ferreira D, Burandt CL Jr, Setola V, Roth BL, Zjawiony JK.

Phytochemistry. 2013 Jul;91:229-35. doi: 10.1016/j.phytochem.2012.02.021. Epub 2012 Mar 21.

44.

Human cytochrome P450scc (CYP11A1) catalyzes epoxide formation with ergosterol.

Tuckey RC, Nguyen MN, Chen J, Slominski AT, Baldisseri DM, Tieu EW, Zjawiony JK, Li W.

Drug Metab Dispos. 2012 Mar;40(3):436-44. doi: 10.1124/dmd.111.042515. Epub 2011 Nov 21.

45.

Salvinorin A has antiinflammatory and antinociceptive effects in experimental models of colitis in mice mediated by KOR and CB1 receptors.

Fichna J, Dicay M, Lewellyn K, Janecka A, Zjawiony JK, MacNaughton WK, Storr MA.

Inflamm Bowel Dis. 2012 Jun;18(6):1137-45. doi: 10.1002/ibd.21873. Epub 2011 Sep 26.

PMID:
21953882
46.

Ultrapotent effects of salvinorin A, a hallucinogenic compound from Salvia divinorum, on LPS-stimulated murine macrophages and its anti-inflammatory action in vivo.

Aviello G, Borrelli F, Guida F, Romano B, Lewellyn K, De Chiaro M, Luongo L, Zjawiony JK, Maione S, Izzo AA, Capasso R.

J Mol Med (Berl). 2011 Sep;89(9):891-902. doi: 10.1007/s00109-011-0752-4. Epub 2011 Apr 16.

PMID:
21499737
47.

Differential effects of salvinorin A on endotoxin-induced hypermotility and neurogenic ion transport in mouse ileum.

Fichna J, Dicay M, Hirota SA, Traboulsi D, Macdonald JA, Janecka A, Beck PL, Zjawiony JK, Macnaughton WK, Storr MA.

Neurogastroenterol Motil. 2011 Jun;23(6):583-e212. doi: 10.1111/j.1365-2982.2011.01699.x. Epub 2011 Mar 17.

PMID:
21414104
48.

Labdane diterpenoids from Leonurus sibiricus.

Wu H, Fronczek FR, Ferreira D, Burandt CL Jr, Zjawiony JK.

J Nat Prod. 2011 Apr 25;74(4):831-6. doi: 10.1021/np100956k. Epub 2011 Mar 4. Erratum in: J Nat Prod. 2011 Jul 22;74(7):1676.

49.

Antileishmanial Germacranolides from Calea zacatechichi.

Wu H, Fronczek FR, Burandt CL Jr, Zjawiony JK.

Planta Med. 2011 May;77(7):749-53. doi: 10.1055/s-0030-1250584. Epub 2010 Dec 2.

PMID:
21128202
50.

Synthesis and biological evaluation of new salvinorin A analogues incorporating natural amino acids.

Fichna J, Lewellyn K, Yan F, Roth BL, Zjawiony JK.

Bioorg Med Chem Lett. 2011 Jan 1;21(1):160-3. doi: 10.1016/j.bmcl.2010.11.046. Epub 2010 Nov 11.

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