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Items: 48

1.

Caloric restriction increases lifespan but affects brain integrity in grey mouse lemur primates.

Pifferi F, Terrien J, Marchal J, Dal-Pan A, Djelti F, Hardy I, Chahory S, Cordonnier N, Desquilbet L, Hurion M, Zahariev A, Chery I, Zizzari P, Perret M, Epelbaum J, Blanc S, Picq JL, Dhenain M, Aujard F.

Commun Biol. 2018 Apr 5;1:30. doi: 10.1038/s42003-018-0024-8. eCollection 2018.

2.

Molecular Integration of Incretin and Glucocorticoid Action Reverses Immunometabolic Dysfunction and Obesity.

Quarta C, Clemmensen C, Zhu Z, Yang B, Joseph SS, Lutter D, Yi CX, Graf E, García-Cáceres C, Legutko B, Fischer K, Brommage R, Zizzari P, Franklin BS, Krueger M, Koch M, Vettorazzi S, Li P, Hofmann SM, Bakhti M, Bastidas-Ponce A, Lickert H, Strom TM, Gailus-Durner V, Bechmann I, Perez-Tilve D, Tuckermann J, Hrabě de Angelis M, Sandoval D, Cota D, Latz E, Seeley RJ, Müller TD, DiMarchi RD, Finan B, Tschöp MH.

Cell Metab. 2017 Oct 3;26(4):620-632.e6. doi: 10.1016/j.cmet.2017.08.023. Epub 2017 Sep 21.

3.

Mild pituitary phenotype in 3- and 12-month-old Aip-deficient male mice.

Lecoq AL, Zizzari P, Hage M, Decourtye L, Adam C, Viengchareun S, Veldhuis JD, Geoffroy V, Lombès M, Tolle V, Guillou A, Karhu A, Kappeler L, Chanson P, Kamenický P.

J Endocrinol. 2016 Oct;231(1):59-69. doi: 10.1530/JOE-16-0190.

PMID:
27621108
4.

Enhanced responsiveness of Ghsr Q343X rats to ghrelin results in enhanced adiposity without increased appetite.

Chebani Y, Marion C, Zizzari P, Chettab K, Pastor M, Korostelev M, Geny D, Epelbaum J, Tolle V, Morisset-Lopez S, Pantel J.

Sci Signal. 2016 Apr 19;9(424):ra39. doi: 10.1126/scisignal.aae0374.

5.

AIP mutations impair AhR signaling in pituitary adenoma patients fibroblasts and in GH3 cells.

Lecoq AL, Viengchareun S, Hage M, Bouligand J, Young J, Boutron A, Zizzari P, Lombès M, Chanson P, Kamenický P.

Endocr Relat Cancer. 2016 May;23(5):433-43. doi: 10.1530/ERC-16-0041. Epub 2016 Apr 14.

PMID:
27080473
6.

Long-Lasting Metabolic Imbalance Related to Obesity Alters Olfactory Tissue Homeostasis and Impairs Olfactory-Driven Behaviors.

Lacroix MC, Caillol M, Durieux D, Monnerie R, Grebert D, Pellerin L, Repond C, Tolle V, Zizzari P, Baly C.

Chem Senses. 2015 Oct;40(8):537-56. doi: 10.1093/chemse/bjv039. Epub 2015 Jul 23.

PMID:
26209545
7.

Physical activity: benefit or weakness in metabolic adaptations in a mouse model of chronic food restriction?

Méquinion M, Caron E, Zgheib S, Stievenard A, Zizzari P, Tolle V, Cortet B, Lucas S, Prévot V, Chauveau C, Viltart O.

Am J Physiol Endocrinol Metab. 2015 Feb 1;308(3):E241-55. doi: 10.1152/ajpendo.00340.2014. Epub 2014 Dec 2.

8.

Ghrelin-Derived Peptides: A Link between Appetite/Reward, GH Axis, and Psychiatric Disorders?

Labarthe A, Fiquet O, Hassouna R, Zizzari P, Lanfumey L, Ramoz N, Grouselle D, Epelbaum J, Tolle V.

Front Endocrinol (Lausanne). 2014 Oct 27;5:163. doi: 10.3389/fendo.2014.00163. eCollection 2014. Review.

9.

Long-term physiological alterations and recovery in a mouse model of separation associated with time-restricted feeding: a tool to study anorexia nervosa related consequences.

Zgheib S, Méquinion M, Lucas S, Leterme D, Ghali O, Tolle V, Zizzari P, Bellefontaine N, Legroux-Gérot I, Hardouin P, Broux O, Viltart O, Chauveau C.

PLoS One. 2014 Aug 4;9(8):e103775. doi: 10.1371/journal.pone.0103775. eCollection 2014.

10.

An early reduction in GH peak amplitude in preproghrelin-deficient male mice has a minor impact on linear growth.

Hassouna R, Zizzari P, Tomasetto C, Veldhuis JD, Fiquet O, Labarthe A, Cognet J, Steyn F, Chen C, Epelbaum J, Tolle V.

Endocrinology. 2014 Sep;155(9):3561-71. doi: 10.1210/en.2014-1126. Epub 2014 Jun 20.

PMID:
24949662
11.

Comparative inhibition of the GH/IGF-I axis obtained with either the targeted secretion inhibitor SXN101959 or the somatostatin analog octreotide in growing male rats.

Somm E, Bonnet N, Zizzari P, Tolle V, Toulotte A, Jones R, Epelbaum J, Martinez A, Hüppi PS, Aubert ML.

Endocrinology. 2013 Nov;154(11):4237-48. doi: 10.1210/en.2013-1427. Epub 2013 Sep 12.

PMID:
24029240
12.

QTLs influencing IGF-1 levels in a LOU/CxFischer 344F2 rat population. Tracks towards the metabolic theory of Ageing.

Marissal-Arvy N, Duron E, Parmentier F, Zizzari P, Mormède P, Epelbaum J.

Growth Horm IGF Res. 2013 Dec;23(6):220-8. doi: 10.1016/j.ghir.2013.08.002. Epub 2013 Aug 19.

PMID:
24028904
13.

Actions of Agonists and Antagonists of the ghrelin/GHS-R Pathway on GH Secretion, Appetite, and cFos Activity.

Hassouna R, Labarthe A, Zizzari P, Videau C, Culler M, Epelbaum J, Tolle V.

Front Endocrinol (Lausanne). 2013 Mar 18;4:25. doi: 10.3389/fendo.2013.00025. eCollection 2013.

14.

A natural variant of obestatin, Q90L, inhibits ghrelin's action on food intake and GH secretion and targets NPY and GHRH neurons in mice.

Hassouna R, Zizzari P, Viltart O, Yang SK, Gardette R, Videau C, Badoer E, Epelbaum J, Tolle V.

PLoS One. 2012;7(12):e51135. doi: 10.1371/journal.pone.0051135. Epub 2012 Dec 10.

15.

Meal anticipatory rise in acylated ghrelin at dark onset is blunted after long-term fasting in rats.

Zizzari P, Hassouna R, Longchamps R, Epelbaum J, Tolle V.

J Neuroendocrinol. 2011 Sep;23(9):804-14. doi: 10.1111/j.1365-2826.2011.02183.x.

PMID:
21722214
16.

Physiological responses to chronic heat exposure in an aging non-human primate species, the gray mouse lemur (Microcebus murinus).

Terrien J, Blanc S, Zizzari P, Epelbaum J, Aujard F.

Exp Gerontol. 2011 Sep;46(9):747-54. doi: 10.1016/j.exger.2011.05.007. Epub 2011 May 19.

PMID:
21620941
17.

Physiological roles of preproghrelin-derived peptides in GH secretion and feeding.

Zizzari P, Hassouna R, Grouselle D, Epelbaum J, Tolle V.

Peptides. 2011 Nov;32(11):2274-82. doi: 10.1016/j.peptides.2011.04.014. Epub 2011 Apr 16. Review.

PMID:
21530598
18.

Loss-of-function mutations in sodium channel Nav1.7 cause anosmia.

Weiss J, Pyrski M, Jacobi E, Bufe B, Willnecker V, Schick B, Zizzari P, Gossage SJ, Greer CA, Leinders-Zufall T, Woods CG, Wood JN, Zufall F.

Nature. 2011 Apr 14;472(7342):186-90. doi: 10.1038/nature09975. Epub 2011 Mar 23.

19.

Scheduled feeding results in adipogenesis and increased acylated ghrelin.

Verbaeys I, Tolle V, Swennen Q, Zizzari P, Buyse J, Epelbaum J, Cokelaere M.

Am J Physiol Endocrinol Metab. 2011 Jun;300(6):E1103-11. doi: 10.1152/ajpendo.00551.2010. Epub 2011 Mar 22.

20.

Caloric restriction or resveratrol supplementation and ageing in a non-human primate: first-year outcome of the RESTRIKAL study in Microcebus murinus.

Dal-Pan A, Terrien J, Pifferi F, Botalla R, Hardy I, Marchal J, Zahariev A, Chery I, Zizzari P, Perret M, Picq JL, Epelbaum J, Blanc S, Aujard F.

Age (Dordr). 2011 Mar;33(1):15-31. doi: 10.1007/s11357-010-9156-6. Epub 2010 Jun 9.

21.

The ghrelin/obestatin balance in the physiological and pathological control of growth hormone secretion, body composition and food intake.

Hassouna R, Zizzari P, Tolle V.

J Neuroendocrinol. 2010 Jul;22(7):793-804. doi: 10.1111/j.1365-2826.2010.02019.x. Epub 2010 May 6. Review.

PMID:
20456603
22.

Role of the ghrelin/obestatin balance in the regulation of neuroendocrine circuits controlling body composition and energy homeostasis.

Epelbaum J, Bedjaoui N, Dardennes R, Feng DD, Gardette R, Grouselle D, Loudes C, Simon A, Tolle V, Yang SK, Zizzari P.

Mol Cell Endocrinol. 2010 Jan 27;314(2):244-7. doi: 10.1016/j.mce.2009.08.026. Epub 2009 Sep 4. Review.

PMID:
19733621
23.
24.

Growth hormone excess and sternohyoid muscle mechanics in rats.

Attal P, Claes V, Bobin S, Chanson P, Kamenicky P, Zizzari P, Lecarpentier Y.

Eur Respir J. 2009 Oct;34(4):967-74. doi: 10.1183/09031936.00171808. Epub 2009 Apr 8.

25.

Ghrelin/obestatin ratio in two populations with low bodyweight: constitutional thinness and anorexia nervosa.

Germain N, Galusca B, Grouselle D, Frere D, Tolle V, Zizzari P, Lang F, Epelbaum J, Estour B.

Psychoneuroendocrinology. 2009 Apr;34(3):413-9. doi: 10.1016/j.psyneuen.2008.10.001. Epub 2008 Nov 7.

PMID:
18995969
26.

Pulsatile cerebrospinal fluid and plasma ghrelin in relation to growth hormone secretion and food intake in the sheep.

Grouselle D, Chaillou E, Caraty A, Bluet-Pajot MT, Zizzari P, Tillet Y, Epelbaum J.

J Neuroendocrinol. 2008 Oct;20(10):1138-46. doi: 10.1111/j.1365-2826.2008.01770.x. Epub 2008 Jul 30.

27.

Effects of age on thermoregulatory responses during cold exposure in a nonhuman primate, Microcebus murinus.

Terrien J, Zizzari P, Bluet-Pajot MT, Henry PY, Perret M, Epelbaum J, Aujard F.

Am J Physiol Regul Integr Comp Physiol. 2008 Aug;295(2):R696-703. doi: 10.1152/ajpregu.00629.2007. Epub 2008 Jun 11.

28.

Epithelial sodium channel is a key mediator of growth hormone-induced sodium retention in acromegaly.

Kamenicky P, Viengchareun S, Blanchard A, Meduri G, Zizzari P, Imbert-Teboul M, Doucet A, Chanson P, Lombès M.

Endocrinology. 2008 Jul;149(7):3294-305. doi: 10.1210/en.2008-0143. Epub 2008 Apr 3.

29.

Obestatin partially affects ghrelin stimulation of food intake and growth hormone secretion in rodents.

Zizzari P, Longchamps R, Epelbaum J, Bluet-Pajot MT.

Endocrinology. 2007 Apr;148(4):1648-53. Epub 2007 Jan 4.

30.

Family trios analysis of common polymorphisms in the obestatin/ghrelin, BDNF and AGRP genes in patients with Anorexia nervosa: association with subtype, body-mass index, severity and age of onset.

Dardennes RM, Zizzari P, Tolle V, Foulon C, Kipman A, Romo L, Iancu-Gontard D, Boni C, Sinet PM, Thérèse Bluet M, Estour B, Mouren MC, Guelfi JD, Rouillon F, Gorwood P, Epelbaum J.

Psychoneuroendocrinology. 2007 Feb;32(2):106-13. Epub 2007 Jan 2.

PMID:
17197106
31.

Cellular localization of apelin and its receptor in the anterior pituitary: evidence for a direct stimulatory action of apelin on ACTH release.

Reaux-Le Goazigo A, Alvear-Perez R, Zizzari P, Epelbaum J, Bluet-Pajot MT, Llorens-Cortes C.

Am J Physiol Endocrinol Metab. 2007 Jan;292(1):E7-15. Epub 2006 Aug 8.

32.

Pituitary cocaine- and amphetamine-regulated transcript expression depends on the strain, sex and oestrous cycle in the rat.

Kappeler L, Gautron L, Layé S, Dantzer R, Zizzari P, Epelbaum J, Bluet-Pajot MT.

J Neuroendocrinol. 2006 Jun;18(6):426-33.

PMID:
16684132
33.

Donepezil restores GH secretion in old rats without affecting the sleep/wake cycle.

Zizzari P, Bassant MH, Poindessous-Jazat F, Epelbaum J, Bluet-Pajot MT.

Neurobiol Aging. 2006 May;27(5):784.e1-784.e5. Epub 2005 Sep 30.

PMID:
16199109
34.

[Ghrelin: a striking example of neuroendocrine peptide pleiotropy].

Bluet-Pajot MT, Tolle V, Zizzari P, Tomasetto C, Grouselle D, Epelbaum J.

Med Sci (Paris). 2005 Aug-Sep;21(8-9):715-21. Review. French.

35.

A century of GH research revisited: from linear models to network complexity.

Kordon C, Zizzari P, Bluet-Pajot MT.

J Endocrinol Invest. 2005;28(5 Suppl):2-9.

PMID:
16114267
36.

Endogenous ghrelin regulates episodic growth hormone (GH) secretion by amplifying GH Pulse amplitude: evidence from antagonism of the GH secretagogue-R1a receptor.

Zizzari P, Halem H, Taylor J, Dong JZ, Datta R, Culler MD, Epelbaum J, Bluet-Pajot MT.

Endocrinology. 2005 Sep;146(9):3836-42. Epub 2005 May 26.

PMID:
15919752
37.

Delayed age-associated decrease in growth hormone pulsatile secretion and increased orexigenic peptide expression in the Lou C/JaLL rat.

Kappeler L, Zizzari P, Alliot J, Epelbaum J, Bluet-Pajot MT.

Neuroendocrinology. 2004;80(5):273-83. Epub 2005 Jan 25.

PMID:
15677878
38.
39.

The role of the small bowel in the regulation of circulating ghrelin levels and food intake in the obese Zucker rat.

Rubino F, Zizzari P, Tomasetto C, Bluet-Pajot MT, Forgione A, Vix M, Grouselle D, Marescaux J.

Endocrinology. 2005 Apr;146(4):1745-51. Epub 2004 Dec 29.

PMID:
15625244
40.

Novel analogs of ghrelin: physiological and clinical implications.

Halem HA, Taylor JE, Dong JZ, Shen Y, Datta R, Abizaid A, Diano S, Horvath T, Zizzari P, Bluet-Pajot MT, Epelbaum J, Culler MD.

Eur J Endocrinol. 2004 Aug;151 Suppl 1:S71-5.

PMID:
15339248
41.

Age-associated changes in hypothalamic and pituitary neuroendocrine gene expression in the rat.

Kappeler L, Gourdji D, Zizzari P, Bluet-Pajot MT, Epelbaum J.

J Neuroendocrinol. 2003 Jun;15(6):592-601.

PMID:
12716410
42.

Biological activity of somatostatin receptors in GC rat tumour somatotrophs: evidence with sst1-sst5 receptor-selective nonpeptidyl agonists.

Cervia D, Zizzari P, Pavan B, Schuepbach E, Langenegger D, Hoyer D, Biondi C, Epelbaum J, Bagnoli P.

Neuropharmacology. 2003 Apr;44(5):672-85.

PMID:
12668053
43.

Balance in ghrelin and leptin plasma levels in anorexia nervosa patients and constitutionally thin women.

Tolle V, Kadem M, Bluet-Pajot MT, Frere D, Foulon C, Bossu C, Dardennes R, Mounier C, Zizzari P, Lang F, Epelbaum J, Estour B.

J Clin Endocrinol Metab. 2003 Jan;88(1):109-16.

PMID:
12519838
44.

Ultradian rhythmicity of ghrelin secretion in relation with GH, feeding behavior, and sleep-wake patterns in rats.

Tolle V, Bassant MH, Zizzari P, Poindessous-Jazat F, Tomasetto C, Epelbaum J, Bluet-Pajot MT.

Endocrinology. 2002 Apr;143(4):1353-61.

PMID:
11897692
45.

[Neuroendocrine aging].

Epelbaum J, Bassant MH, Bluet-Pajot MT, Gourdji D, Jazat-Poindessous F, Kappeler L, Zizzari P.

Ann Biol Clin (Paris). 2001 Jul-Aug;59(4):437-44. Review. French. No abstract available.

46.

Growth hormone secretagogues and hypothalamic networks.

Bluet-Pajot MT, Tolle V, Zizzari P, Robert C, Hammond C, Mitchell V, Beauvillain JC, Viollet C, Epelbaum J, Kordon C.

Endocrine. 2001 Feb;14(1):1-8. Review.

PMID:
11322489
47.

In vivo and in vitro effects of ghrelin/motilin-related peptide on growth hormone secretion in the rat.

Tolle V, Zizzari P, Tomasetto C, Rio MC, Epelbaum J, Bluet-Pajot MT.

Neuroendocrinology. 2001 Jan;73(1):54-61.

PMID:
11174017
48.

Involvement of the Sst1 somatostatin receptor subtype in the intrahypothalamic neuronal network regulating growth hormone secretion: an in vitro and in vivo antisense study.

Lanneau C, Bluet-Pajot MT, Zizzari P, Csaba Z, Dournaud P, Helboe L, Hoyer D, Pellegrini E, Tannenbaum GS, Epelbaum J, Gardette R.

Endocrinology. 2000 Mar;141(3):967-79.

PMID:
10698172

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