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Items: 15

1.

Vav3-induced cytoskeletal dynamics contribute to heterotypic properties of endothelial barriers.

Hilfenhaus G, Nguyen DP, Freshman J, Prajapati D, Ma F, Song D, Ziyad S, Cuadrado M, Pellegrini M, Bustelo XR, Iruela-Arispe ML.

J Cell Biol. 2018 Aug 6;217(8):2813-2830. doi: 10.1083/jcb.201706041. Epub 2018 Jun 1.

2.

A Forward Genetic Screen Targeting the Endothelium Reveals a Regulatory Role for the Lipid Kinase Pi4ka in Myelo- and Erythropoiesis.

Ziyad S, Riordan JD, Cavanaugh AM, Su T, Hernandez GE, Hilfenhaus G, Morselli M, Huynh K, Wang K, Chen JN, Dupuy AJ, Iruela-Arispe ML.

Cell Rep. 2018 Jan 30;22(5):1211-1224. doi: 10.1016/j.celrep.2018.01.017.

3.

Correction: Decoupling of the PI3K Pathway via Mutation Necessitates Combinatorial Treatment in HER2+ Breast Cancer.

Korkola JE, Collisson EA, Heiser LM, Oates C, Bayani N, Itani S, Esch A, Thompson W, Griffith OL, Wang NJ, Kuo WL, Cooper B, Billig J, Ziyad S, Hung JL, Jakkula L, Feiler H, Lu Y, Mills GB, Spellman PT, Tomlin C, Mukherjee S, Gray JW.

PLoS One. 2017 Oct 11;12(10):e0186551. doi: 10.1371/journal.pone.0186551. eCollection 2017.

4.

Perivascular Macrophages Limit Permeability.

He H, Mack JJ, Güç E, Warren CM, Squadrito ML, Kilarski WW, Baer C, Freshman RD, McDonald AI, Ziyad S, Swartz MA, De Palma M, Iruela-Arispe ML.

Arterioscler Thromb Vasc Biol. 2016 Nov;36(11):2203-2212. Epub 2016 Sep 15.

5.

Decoupling of the PI3K Pathway via Mutation Necessitates Combinatorial Treatment in HER2+ Breast Cancer.

Korkola JE, Collisson EA, Heiser M, Oates C, Bayani N, Itani S, Esch A, Thompson W, Griffith OL, Wang NJ, Kuo WL, Cooper B, Billig J, Ziyad S, Hung JL, Jakkula L, Feiler H, Lu Y, Mills GB, Spellman PT, Tomlin C, Mukherjee S, Gray JW.

PLoS One. 2015 Jul 16;10(7):e0133219. doi: 10.1371/journal.pone.0133219. eCollection 2015. Erratum in: PLoS One. 2017 Oct 11;12 (10 ):e0186551.

6.

Autocrine VEGF maintains endothelial survival through regulation of metabolism and autophagy.

Domigan CK, Warren CM, Antanesian V, Happel K, Ziyad S, Lee S, Krall A, Duan L, Torres-Collado AX, Castellani LW, Elashoff D, Christofk HR, van der Bliek AM, Potente M, Iruela-Arispe ML.

J Cell Sci. 2015 Jun 15;128(12):2236-48. doi: 10.1242/jcs.163774. Epub 2015 May 8.

7.

Canonical and noncanonical vascular endothelial growth factor pathways: new developments in biology and signal transduction.

Domigan CK, Ziyad S, Iruela-Arispe ML.

Arterioscler Thromb Vasc Biol. 2015 Jan;35(1):30-9. doi: 10.1161/ATVBAHA.114.303215. Epub 2014 Oct 2. Review.

8.

A ligand-independent VEGFR2 signaling pathway limits angiogenic responses in diabetes.

Warren CM, Ziyad S, Briot A, Der A, Iruela-Arispe ML.

Sci Signal. 2014 Jan 7;7(307):ra1. doi: 10.1126/scisignal.2004235.

9.

Molecular mechanisms of tumor angiogenesis.

Ziyad S, Iruela-Arispe ML.

Genes Cancer. 2011 Dec;2(12):1085-96. doi: 10.1177/1947601911432334.

10.

Integrating biological knowledge into variable selection: an empirical Bayes approach with an application in cancer biology.

Hill SM, Neve RM, Bayani N, Kuo WL, Ziyad S, Spellman PT, Gray JW, Mukherjee S.

BMC Bioinformatics. 2012 May 11;13:94. doi: 10.1186/1471-2105-13-94.

11.

Subtype and pathway specific responses to anticancer compounds in breast cancer.

Heiser LM, Sadanandam A, Kuo WL, Benz SC, Goldstein TC, Ng S, Gibb WJ, Wang NJ, Ziyad S, Tong F, Bayani N, Hu Z, Billig JI, Dueregger A, Lewis S, Jakkula L, Korkola JE, Durinck S, Pepin F, Guan Y, Purdom E, Neuvial P, Bengtsson H, Wood KW, Smith PG, Vassilev LT, Hennessy BT, Greshock J, Bachman KE, Hardwicke MA, Park JW, Marton LJ, Wolf DM, Collisson EA, Neve RM, Mills GB, Speed TP, Feiler HS, Wooster RF, Haussler D, Stuart JM, Gray JW, Spellman PT.

Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2724-9. doi: 10.1073/pnas.1018854108. Epub 2011 Oct 14.

12.

Activity of the kinesin spindle protein inhibitor ispinesib (SB-715992) in models of breast cancer.

Purcell JW, Davis J, Reddy M, Martin S, Samayoa K, Vo H, Thomsen K, Bean P, Kuo WL, Ziyad S, Billig J, Feiler HS, Gray JW, Wood KW, Cases S.

Clin Cancer Res. 2010 Jan 15;16(2):566-76. doi: 10.1158/1078-0432.CCR-09-1498. Epub 2010 Jan 12.

13.

A systems analysis of the chemosensitivity of breast cancer cells to the polyamine analogue PG-11047.

Kuo WL, Das D, Ziyad S, Bhattacharya S, Gibb WJ, Heiser LM, Sadanandam A, Fontenay GV, Hu Z, Wang NJ, Bayani N, Feiler HS, Neve RM, Wyrobek AJ, Spellman PT, Marton LJ, Gray JW.

BMC Med. 2009 Dec 14;7:77. doi: 10.1186/1741-7015-7-77.

14.

Integrated analysis of breast cancer cell lines reveals unique signaling pathways.

Heiser LM, Wang NJ, Talcott CL, Laderoute KR, Knapp M, Guan Y, Hu Z, Ziyad S, Weber BL, Laquerre S, Jackson JR, Wooster RF, Kuo WL, Gray JW, Spellman PT.

Genome Biol. 2009;10(3):R31. doi: 10.1186/gb-2009-10-3-r31. Epub 2009 Mar 25.

15.

Sparse combinatorial inference with an application in cancer biology.

Mukherjee S, Pelech S, Neve RM, Kuo WL, Ziyad S, Spellman PT, Gray JW, Speed TP.

Bioinformatics. 2009 Jan 15;25(2):265-71. doi: 10.1093/bioinformatics/btn611. Epub 2008 Nov 27.

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