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Items: 1 to 50 of 69

1.

Mitochondrial Alkbh1 localizes to mtRNA granules and its knockdown induces the mitochondrial UPR in humans and C. elegans.

Wagner A, Hofmeister O, Rolland SG, Maiser A, Aasumets K, Schmitt S, Schorpp K, Feuchtinger A, Hadian K, Schneider S, Zischka H, Leonhardt H, Conradt B, Gerhold JM, Wolf A.

J Cell Sci. 2019 Oct 1;132(19). pii: jcs223891. doi: 10.1242/jcs.223891.

PMID:
31434717
2.

Antioxidant Versus Pro-Apoptotic Effects of Mushroom-Enriched Diets on Mitochondria in Liver Disease.

Fontes A, Alemany-Pagès M, Oliveira PJ, Ramalho-Santos J, Zischka H, Azul AM.

Int J Mol Sci. 2019 Aug 16;20(16). pii: E3987. doi: 10.3390/ijms20163987. Review.

3.

Connecting lysosomes and mitochondria - a novel role for lipid metabolism in cancer cell death.

Bartel K, Pein H, Popper B, Schmitt S, Janaki-Raman S, Schulze A, Lengauer F, Koeberle A, Werz O, Zischka H, Müller R, Vollmar AM, von Schwarzenberg K.

Cell Commun Signal. 2019 Jul 29;17(1):87. doi: 10.1186/s12964-019-0399-2.

4.

Linking bioenergetic function of mitochondria to tissue-specific molecular fingerprints.

Kappler L, Hoene M, Hu C, von Toerne C, Li J, Bleher D, Hoffmann C, Böhm A, Kollipara L, Zischka H, Königsrainer A, Häring HU, Peter A, Xu G, Sickmann A, Hauck SM, Weigert C, Lehmann R.

Am J Physiol Endocrinol Metab. 2019 Aug 1;317(2):E374-E387. doi: 10.1152/ajpendo.00088.2019. Epub 2019 Jun 18.

PMID:
31211616
5.

Single organelle analysis to characterize mitochondrial function and crosstalk during viral infection.

Schneider A, Kurz S, Manske K, Janas M, Heikenwälder M, Misgeld T, Aichler M, Weissmann SF, Zischka H, Knolle P, Wohlleber D.

Sci Rep. 2019 Jun 11;9(1):8492. doi: 10.1038/s41598-019-44922-9.

6.

A High-Calorie Diet Aggravates Mitochondrial Dysfunction and Triggers Severe Liver Damage in Wilson Disease Rats.

Einer C, Leitzinger C, Lichtmannegger J, Eberhagen C, Rieder T, Borchard S, Wimmer R, Denk G, Popper B, Neff F, Polishchuk EV, Polishchuk RS, Hauck SM, von Toerne C, Müller JC, Karst U, Baral BS, DiSpirito AA, Kremer AE, Semrau J, Weiss KH, Hohenester S, Zischka H.

Cell Mol Gastroenterol Hepatol. 2019;7(3):571-596. doi: 10.1016/j.jcmgh.2018.12.005. Epub 2018 Dec 23.

7.

Activation of Autophagy, Observed in Liver Tissues From Patients With Wilson Disease and From ATP7B-Deficient Animals, Protects Hepatocytes From Copper-Induced Apoptosis.

Polishchuk EV, Merolla A, Lichtmannegger J, Romano A, Indrieri A, Ilyechova EY, Concilli M, De Cegli R, Crispino R, Mariniello M, Petruzzelli R, Ranucci G, Iorio R, Pietrocola F, Einer C, Borchard S, Zibert A, Schmidt HH, Di Schiavi E, Puchkova LV, Franco B, Kroemer G, Zischka H, Polishchuk RS.

Gastroenterology. 2019 Mar;156(4):1173-1189.e5. doi: 10.1053/j.gastro.2018.11.032. Epub 2018 Nov 17.

PMID:
30452922
8.

Mitochondria and Reactive Oxygen Species in Aging and Age-Related Diseases.

Giorgi C, Marchi S, Simoes ICM, Ren Z, Morciano G, Perrone M, Patalas-Krawczyk P, Borchard S, Jędrak P, Pierzynowska K, Szymański J, Wang DQ, Portincasa P, Węgrzyn G, Zischka H, Dobrzyn P, Bonora M, Duszynski J, Rimessi A, Karkucinska-Wieckowska A, Dobrzyn A, Szabadkai G, Zavan B, Oliveira PJ, Sardao VA, Pinton P, Wieckowski MR.

Int Rev Cell Mol Biol. 2018;340:209-344. doi: 10.1016/bs.ircmb.2018.05.006. Epub 2018 Jun 22. Review.

PMID:
30072092
9.

Mitochondrial copper homeostasis and its derailment in Wilson disease.

Zischka H, Einer C.

Int J Biochem Cell Biol. 2018 Sep;102:71-75. doi: 10.1016/j.biocel.2018.07.001. Epub 2018 Jul 8. Review.

10.

High spatial resolution LA-ICP-MS demonstrates massive liver copper depletion in Wilson disease rats upon Methanobactin treatment.

Müller JC, Lichtmannegger J, Zischka H, Sperling M, Karst U.

J Trace Elem Med Biol. 2018 Sep;49:119-127. doi: 10.1016/j.jtemb.2018.05.009. Epub 2018 May 9.

PMID:
29895360
11.

The exceptional sensitivity of brain mitochondria to copper.

Borchard S, Bork F, Rieder T, Eberhagen C, Popper B, Lichtmannegger J, Schmitt S, Adamski J, Klingenspor M, Weiss KH, Zischka H.

Toxicol In Vitro. 2018 Sep;51:11-22. doi: 10.1016/j.tiv.2018.04.012. Epub 2018 Apr 30.

12.

PPARα Is Necessary for Radiation-Induced Activation of Noncanonical TGFβ Signaling in the Heart.

Subramanian V, Borchard S, Azimzadeh O, Sievert W, Merl-Pham J, Mancuso M, Pasquali E, Multhoff G, Popper B, Zischka H, Atkinson MJ, Tapio S.

J Proteome Res. 2018 Apr 6;17(4):1677-1689. doi: 10.1021/acs.jproteome.8b00001. Epub 2018 Mar 23.

PMID:
29560722
13.

Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis.

Ingold I, Berndt C, Schmitt S, Doll S, Poschmann G, Buday K, Roveri A, Peng X, Porto Freitas F, Seibt T, Mehr L, Aichler M, Walch A, Lamp D, Jastroch M, Miyamoto S, Wurst W, Ursini F, Arnér ESJ, Fradejas-Villar N, Schweizer U, Zischka H, Friedmann Angeli JP, Conrad M.

Cell. 2018 Jan 25;172(3):409-422.e21. doi: 10.1016/j.cell.2017.11.048. Epub 2017 Dec 28.

14.

Mitochondria in non-alcoholic fatty liver disease.

Simões ICM, Fontes A, Pinton P, Zischka H, Wieckowski MR.

Int J Biochem Cell Biol. 2018 Feb;95:93-99. doi: 10.1016/j.biocel.2017.12.019. Epub 2017 Dec 26. Review.

15.

Copper Directly Affects Intestinal Lipid Turnover.

Weiss KH, Zischka H.

Gastroenterology. 2018 Jan;154(1):15-17. doi: 10.1053/j.gastro.2017.11.016. Epub 2017 Nov 21. No abstract available.

PMID:
29174544
16.

Data on chow, liver tissue and mitochondrial fatty acid compositions as well as mitochondrial proteome changes after feeding mice a western diet for 6-24 weeks.

Einer C, Hohenester S, Wimmer R, Wottke L, Artmann R, Schulz S, Gosmann C, Simmons A, Leitzinger C, Eberhagen C, Borchard S, Schmitt S, Hauck SM, von Toerne C, Jastroch M, Walheim E, Rust C, Gerbes AL, Popper B, Mayr D, Schnurr M, Vollmar AM, Denk G, Zischka H.

Data Brief. 2017 Sep 18;15:163-169. doi: 10.1016/j.dib.2017.09.019. eCollection 2017 Dec.

17.

Spatial investigation of the elemental distribution in Wilson's disease liver after d-penicillamine treatment by LA-ICP-MS.

Hachmöller O, Zibert A, Zischka H, Sperling M, Groba SR, Grünewald I, Wardelmann E, Schmidt HH, Karst U.

J Trace Elem Med Biol. 2017 Dec;44:26-31. doi: 10.1016/j.jtemb.2017.05.008. Epub 2017 May 29.

PMID:
28965585
18.

Mitochondrial adaptation in steatotic mice.

Einer C, Hohenester S, Wimmer R, Wottke L, Artmann R, Schulz S, Gosmann C, Simmons A, Leitzinger C, Eberhagen C, Borchard S, Schmitt S, Hauck SM, von Toerne C, Jastroch M, Walheim E, Rust C, Gerbes AL, Popper B, Mayr D, Schnurr M, Vollmar AM, Denk G, Zischka H.

Mitochondrion. 2018 May;40:1-12. doi: 10.1016/j.mito.2017.08.015. Epub 2017 Sep 19.

PMID:
28935446
19.

Downregulation of hepatic multi-drug resistance protein 1 (MDR1) after copper exposure.

Groba SR, Guttmann S, Niemietz C, Bernick F, Sauer V, Hachmöller O, Karst U, Zischka H, Zibert A, Schmidt HH.

Metallomics. 2017 Sep 20;9(9):1279-1287. doi: 10.1039/c7mt00189d.

PMID:
28805879
20.

Antioxidant defense in quiescent cells determines selectivity of electron transport chain inhibition-induced cell death.

Blecha J, Novais SM, Rohlenova K, Novotna E, Lettlova S, Schmitt S, Zischka H, Neuzil J, Rohlena J.

Free Radic Biol Med. 2017 Nov;112:253-266. doi: 10.1016/j.freeradbiomed.2017.07.033. Epub 2017 Jul 31.

PMID:
28774815
21.

Live cell imaging of mitochondria following targeted irradiation in situ reveals rapid and highly localized loss of membrane potential.

Walsh DWM, Siebenwirth C, Greubel C, Ilicic K, Reindl J, Girst S, Muggiolu G, Simon M, Barberet P, Seznec H, Zischka H, Multhoff G, Schmid TE, Dollinger G.

Sci Rep. 2017 Apr 25;7:46684. doi: 10.1038/srep46684.

22.

SK2 channels regulate mitochondrial respiration and mitochondrial Ca2+ uptake.

Honrath B, Matschke L, Meyer T, Magerhans L, Perocchi F, Ganjam GK, Zischka H, Krasel C, Gerding A, Bakker BM, Bünemann M, Strack S, Decher N, Culmsee C, Dolga AM.

Cell Death Differ. 2017 May;24(5):761-773. doi: 10.1038/cdd.2017.2. Epub 2017 Mar 10.

23.

Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival.

Chubanov V, Ferioli S, Wisnowsky A, Simmons DG, Leitzinger C, Einer C, Jonas W, Shymkiv Y, Bartsch H, Braun A, Akdogan B, Mittermeier L, Sytik L, Torben F, Jurinovic V, van der Vorst EP, Weber C, Yildirim ÖA, Sotlar K, Schürmann A, Zierler S, Zischka H, Ryazanov AG, Gudermann T.

Elife. 2016 Dec 19;5. pii: e20914. doi: 10.7554/eLife.20914.

24.

Identification of proliferative and mature β-cells in the islets of Langerhans.

Bader E, Migliorini A, Gegg M, Moruzzi N, Gerdes J, Roscioni SS, Bakhti M, Brandl E, Irmler M, Beckers J, Aichler M, Feuchtinger A, Leitzinger C, Zischka H, Wang-Sattler R, Jastroch M, Tschöp M, Machicao F, Staiger H, Häring HU, Chmelova H, Chouinard JA, Oskolkov N, Korsgren O, Speier S, Lickert H.

Nature. 2016 Jul 21;535(7612):430-4. Epub 2016 Jul 11.

PMID:
27398620
25.

Methanobactin reverses acute liver failure in a rat model of Wilson disease.

Lichtmannegger J, Leitzinger C, Wimmer R, Schmitt S, Schulz S, Kabiri Y, Eberhagen C, Rieder T, Janik D, Neff F, Straub BK, Schirmacher P, DiSpirito AA, Bandow N, Baral BS, Flatley A, Kremmer E, Denk G, Reiter FP, Hohenester S, Eckardt-Schupp F, Dencher NA, Adamski J, Sauer V, Niemietz C, Schmidt HH, Merle U, Gotthardt DN, Kroemer G, Weiss KH, Zischka H.

J Clin Invest. 2016 Jul 1;126(7):2721-35. doi: 10.1172/JCI85226. Epub 2016 Jun 20.

26.

A TonB-Dependent Transporter Is Responsible for Methanobactin Uptake by Methylosinus trichosporium OB3b.

Gu W, Farhan Ul Haque M, Baral BS, Turpin EA, Bandow NL, Kremmer E, Flatley A, Zischka H, DiSpirito AA, Semrau JD.

Appl Environ Microbiol. 2016 Jan 15;82(6):1917-1923. doi: 10.1128/AEM.03884-15.

27.

Heart-Specific Knockout of the Mitochondrial Thioredoxin Reductase (Txnrd2) Induces Metabolic and Contractile Dysfunction in the Aging Myocardium.

Kiermayer C, Northrup E, Schrewe A, Walch A, de Angelis MH, Schoensiegel F, Zischka H, Prehn C, Adamski J, Bekeredjian R, Ivandic B, Kupatt C, Brielmeier M.

J Am Heart Assoc. 2015 Jul 21;4(7). pii: e002153. doi: 10.1161/JAHA.115.002153.

28.

Isolation of mitochondria from cultured cells and liver tissue biopsies for molecular and biochemical analyses.

Schmitt S, Eberhagen C, Weber S, Aichler M, Zischka H.

Methods Mol Biol. 2015;1295:87-97. doi: 10.1007/978-1-4939-2550-6_8.

PMID:
25820716
29.

A protocol for the parallel isolation of intact mitochondria from rat liver, kidney, heart, and brain.

Schulz S, Lichtmannegger J, Schmitt S, Leitzinger C, Eberhagen C, Einer C, Kerth J, Aichler M, Zischka H.

Methods Mol Biol. 2015;1295:75-86. doi: 10.1007/978-1-4939-2550-6_7.

PMID:
25820715
30.

Impaired autophagy induces chronic atrophic pancreatitis in mice via sex- and nutrition-dependent processes.

Diakopoulos KN, Lesina M, Wörmann S, Song L, Aichler M, Schild L, Artati A, Römisch-Margl W, Wartmann T, Fischer R, Kabiri Y, Zischka H, Halangk W, Demir IE, Pilsak C, Walch A, Mantzoros CS, Steiner JM, Erkan M, Schmid RM, Witt H, Adamski J, Algül H.

Gastroenterology. 2015 Mar;148(3):626-638.e17. doi: 10.1053/j.gastro.2014.12.003. Epub 2014 Dec 11.

PMID:
25497209
31.

Metabolic activation of intrahepatic CD8+ T cells and NKT cells causes nonalcoholic steatohepatitis and liver cancer via cross-talk with hepatocytes.

Wolf MJ, Adili A, Piotrowitz K, Abdullah Z, Boege Y, Stemmer K, Ringelhan M, Simonavicius N, Egger M, Wohlleber D, Lorentzen A, Einer C, Schulz S, Clavel T, Protzer U, Thiele C, Zischka H, Moch H, Tschöp M, Tumanov AV, Haller D, Unger K, Karin M, Kopf M, Knolle P, Weber A, Heikenwalder M.

Cancer Cell. 2014 Oct 13;26(4):549-64. doi: 10.1016/j.ccell.2014.09.003.

32.

Targeting the actin cytoskeleton: selective antitumor action via trapping PKCɛ.

Foerster F, Braig S, Moser C, Kubisch R, Busse J, Wagner E, Schmoeckel E, Mayr D, Schmitt S, Huettel S, Zischka H, Mueller R, Vollmar AM.

Cell Death Dis. 2014 Aug 28;5:e1398. doi: 10.1038/cddis.2014.363.

33.

Why to compare absolute numbers of mitochondria.

Schmitt S, Schulz S, Schropp EM, Eberhagen C, Simmons A, Beisker W, Aichler M, Zischka H.

Mitochondrion. 2014 Nov;19 Pt A:113-23. doi: 10.1016/j.mito.2014.06.005. Epub 2014 Jun 23.

PMID:
24969531
34.

Pathological mitochondrial copper overload in livers of Wilson's disease patients and related animal models.

Zischka H, Lichtmannegger J.

Ann N Y Acad Sci. 2014 May;1315:6-15. doi: 10.1111/nyas.12347. Epub 2014 Feb 12. Review.

PMID:
24517326
35.

Subcellular expression and neuroprotective effects of SK channels in human dopaminergic neurons.

Dolga AM, de Andrade A, Meissner L, Knaus HG, Höllerhage M, Christophersen P, Zischka H, Plesnila N, Höglinger GU, Culmsee C.

Cell Death Dis. 2014 Jan 16;5:e999. doi: 10.1038/cddis.2013.530.

36.

A semi-automated method for isolating functionally intact mitochondria from cultured cells and tissue biopsies.

Schmitt S, Saathoff F, Meissner L, Schropp EM, Lichtmannegger J, Schulz S, Eberhagen C, Borchard S, Aichler M, Adamski J, Plesnila N, Rothenfusser S, Kroemer G, Zischka H.

Anal Biochem. 2013 Dec 1;443(1):66-74. doi: 10.1016/j.ab.2013.08.007. Epub 2013 Aug 19.

PMID:
23969012
37.

Progressive stages of mitochondrial destruction caused by cell toxic bile salts.

Schulz S, Schmitt S, Wimmer R, Aichler M, Eisenhofer S, Lichtmannegger J, Eberhagen C, Artmann R, Tookos F, Walch A, Krappmann D, Brenner C, Rust C, Zischka H.

Biochim Biophys Acta. 2013 Sep;1828(9):2121-33. doi: 10.1016/j.bbamem.2013.05.007. Epub 2013 May 17.

38.

Clinical response to chemotherapy in oesophageal adenocarcinoma patients is linked to defects in mitochondria.

Aichler M, Elsner M, Ludyga N, Feuchtinger A, Zangen V, Maier SK, Balluff B, Schöne C, Hierber L, Braselmann H, Meding S, Rauser S, Zischka H, Aubele M, Schmitt M, Feith M, Hauck SM, Ueffing M, Langer R, Kuster B, Zitzelsberger H, Höfler H, Walch AK.

J Pathol. 2013 Aug;230(4):410-9. doi: 10.1002/path.4199.

PMID:
23592244
39.

Ionising radiation induces persistent alterations in the cardiac mitochondrial function of C57BL/6 mice 40 weeks after local heart exposure.

Barjaktarovic Z, Shyla A, Azimzadeh O, Schulz S, Haagen J, Dörr W, Sarioglu H, Atkinson MJ, Zischka H, Tapio S.

Radiother Oncol. 2013 Mar;106(3):404-10. doi: 10.1016/j.radonc.2013.01.017. Epub 2013 Mar 20.

PMID:
23522698
40.

Mitochondrial small conductance SK2 channels prevent glutamate-induced oxytosis and mitochondrial dysfunction.

Dolga AM, Netter MF, Perocchi F, Doti N, Meissner L, Tobaben S, Grohm J, Zischka H, Plesnila N, Decher N, Culmsee C.

J Biol Chem. 2013 Apr 12;288(15):10792-804. doi: 10.1074/jbc.M113.453522. Epub 2013 Feb 19.

41.

Mode of cell death induction by pharmacological vacuolar H+-ATPase (V-ATPase) inhibition.

von Schwarzenberg K, Wiedmann RM, Oak P, Schulz S, Zischka H, Wanner G, Efferth T, Trauner D, Vollmar AM.

J Biol Chem. 2013 Jan 11;288(2):1385-96. doi: 10.1074/jbc.M112.412007. Epub 2012 Nov 20.

42.

Independent transcriptional reprogramming and apoptosis induction by cisplatin.

Galluzzi L, Vitale I, Senovilla L, Eisenberg T, Carmona-Gutierrez D, Vacchelli E, Robert T, Ripoche H, Jägemann N, Paccard C, Servant N, Hupé P, Lazar V, Dessen P, Barillot E, Zischka H, Madeo F, Kroemer G.

Cell Cycle. 2012 Sep 15;11(18):3472-80. doi: 10.4161/cc.21789. Epub 2012 Aug 23.

43.

Prognostic impact of vitamin B6 metabolism in lung cancer.

Galluzzi L, Vitale I, Senovilla L, Olaussen KA, Pinna G, Eisenberg T, Goubar A, Martins I, Michels J, Kratassiouk G, Carmona-Gutierrez D, Scoazec M, Vacchelli E, Schlemmer F, Kepp O, Shen S, Tailler M, Niso-Santano M, Morselli E, Criollo A, Adjemian S, Jemaà M, Chaba K, Pailleret C, Michaud M, Pietrocola F, Tajeddine N, de La Motte Rouge T, Araujo N, Morozova N, Robert T, Ripoche H, Commo F, Besse B, Validire P, Fouret P, Robin A, Dorvault N, Girard P, Gouy S, Pautier P, Jägemann N, Nickel AC, Marsili S, Paccard C, Servant N, Hupé P, Behrens C, Behnam-Motlagh P, Kohno K, Cremer I, Damotte D, Alifano M, Midttun O, Ueland PM, Lazar V, Dessen P, Zischka H, Chatelut E, Castedo M, Madeo F, Barillot E, Thomale J, Wistuba II, Sautès-Fridman C, Zitvogel L, Soria JC, Harel-Bellan A, Kroemer G.

Cell Rep. 2012 Aug 30;2(2):257-69. doi: 10.1016/j.celrep.2012.06.017. Epub 2012 Jul 26.

44.

Tauro-β-muricholic acid restricts bile acid-induced hepatocellular apoptosis by preserving the mitochondrial membrane potential.

Denk GU, Kleiss CP, Wimmer R, Vennegeerts T, Reiter FP, Schulz S, Zischka H, Rust C.

Biochem Biophys Res Commun. 2012 Aug 10;424(4):758-64. doi: 10.1016/j.bbrc.2012.07.029. Epub 2012 Jul 15.

PMID:
22809502
45.

Radiation-induced signaling results in mitochondrial impairment in mouse heart at 4 weeks after exposure to X-rays.

Barjaktarovic Z, Schmaltz D, Shyla A, Azimzadeh O, Schulz S, Haagen J, Dörr W, Sarioglu H, Schäfer A, Atkinson MJ, Zischka H, Tapio S.

PLoS One. 2011;6(12):e27811. doi: 10.1371/journal.pone.0027811. Epub 2011 Dec 8.

46.

Mitochondrial thioredoxin reductase is essential for early postischemic myocardial protection.

Horstkotte J, Perisic T, Schneider M, Lange P, Schroeder M, Kiermayer C, Hinkel R, Ziegler T, Mandal PK, David R, Schulz S, Schmitt S, Widder J, Sinowatz F, Becker BF, Bauersachs J, Naebauer M, Franz WM, Jeremias I, Brielmeier M, Zischka H, Conrad M, Kupatt C.

Circulation. 2011 Dec 20;124(25):2892-902. doi: 10.1161/CIRCULATIONAHA.111.059253. Epub 2011 Dec 5.

PMID:
22144571
47.

Liver mitochondrial membrane crosslinking and destruction in a rat model of Wilson disease.

Zischka H, Lichtmannegger J, Schmitt S, Jägemann N, Schulz S, Wartini D, Jennen L, Rust C, Larochette N, Galluzzi L, Chajes V, Bandow N, Gilles VS, DiSpirito AA, Esposito I, Goettlicher M, Summer KH, Kroemer G.

J Clin Invest. 2011 Apr;121(4):1508-18. doi: 10.1172/JCI45401.

48.

A mathematical model of mitochondrial swelling.

Eisenhofer S, Toókos F, Hense BA, Schulz S, Filbir F, Zischka H.

BMC Res Notes. 2010 Mar 11;3:67. doi: 10.1186/1756-0500-3-67.

49.

Mitochondrial gateways to cancer.

Galluzzi L, Morselli E, Kepp O, Vitale I, Rigoni A, Vacchelli E, Michaud M, Zischka H, Castedo M, Kroemer G.

Mol Aspects Med. 2010 Feb;31(1):1-20. doi: 10.1016/j.mam.2009.08.002. Epub 2009 Aug 19. Review.

PMID:
19698742
50.

16-BAC/SDS-PAGE analysis of membrane proteins of yeast mitochondria purified by free flow electrophoresis.

Braun RJ, Kinkl N, Zischka H, Ueffing M.

Methods Mol Biol. 2009;528:83-107. doi: 10.1007/978-1-60327-310-7_6.

PMID:
19153686

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