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Items: 34

2.

A phase I and pharmacokinetic study of silybin-phytosome in prostate cancer patients.

Flaig TW, Gustafson DL, Su LJ, Zirrolli JA, Crighton F, Harrison GS, Pierson AS, Agarwal R, Glodé LM.

Invest New Drugs. 2007 Apr;25(2):139-46. Epub 2006 Nov 1.

PMID:
17077998
3.

The bioreduction of a series of benzoquinone ansamycins by NAD(P)H:quinone oxidoreductase 1 to more potent heat shock protein 90 inhibitors, the hydroquinone ansamycins.

Guo W, Reigan P, Siegel D, Zirrolli J, Gustafson D, Ross D.

Mol Pharmacol. 2006 Oct;70(4):1194-203. Epub 2006 Jul 6.

PMID:
16825487
4.

Tissue distribution and metabolism of the tyrosine kinase inhibitor ZD6474 (Zactima) in tumor-bearing nude mice following oral dosing.

Gustafson DL, Bradshaw-Pierce EL, Merz AL, Zirrolli JA.

J Pharmacol Exp Ther. 2006 Aug;318(2):872-80. Epub 2006 Apr 27.

PMID:
16644900
5.
6.

Protonation of crotonyl-CoA dienolate by human glutaryl-CoA dehydrogenase occurs by solvent-derived protons.

Rao KS, Albro M, Zirrolli JA, Vander Velde D, Jones DN, Frerman FE.

Biochemistry. 2005 Oct 25;44(42):13932-40.

PMID:
16229482
7.

Rapid and sensitive LC/MS/MS analysis of the novel tyrosine kinase inhibitor ZD6474 in mouse plasma and tissues.

Zirrolli JA, Bradshaw EL, Long ME, Gustafson DL.

J Pharm Biomed Anal. 2005 Sep 15;39(3-4):705-11.

PMID:
15935603
8.

Analysis of docetaxel pharmacokinetics in humans with the inclusion of later sampling time-points afforded by the use of a sensitive tandem LCMS assay.

Gustafson DL, Long ME, Zirrolli JA, Duncan MW, Holden SN, Pierson AS, Eckhardt SG.

Cancer Chemother Pharmacol. 2003 Aug;52(2):159-66. Epub 2003 May 21.

PMID:
12759775
9.

Electrospray ionization and low energy tandem mass spectrometry of polyhydroxy unsaturated fatty acids.

Wheelan P, Zirrolli JA, Murphy RC.

J Am Soc Mass Spectrom. 1996 Feb;7(2):140-9. doi: 10.1016/1044-0305(95)00628-1.

PMID:
24203234
10.

Negative ion electrospray tandem mass spectrometric structural characterization of leukotriene B4 (LTB 4) and LTB 4-derived metabolites.

Wheelan P, Zirrolli JA, Murphy RC.

J Am Soc Mass Spectrom. 1996 Feb;7(2):129-39. doi: 10.1016/1044-0305(95)00629-X.

PMID:
24203233
11.

Analysis of hydroxy fatty acids as pentafluorobenzyl ester, trimethylsilyl ether derivatives by electron ionization gas chromatography/mass spectrometry.

Wheelan P, Zirrolli JA, Murphy RC.

J Am Soc Mass Spectrom. 1995 Jan;6(1):40-51. doi: 10.1016/1044-0305(94)00090-M.

PMID:
24222059
12.

Analysis of long-chain fatty acyl coenzyme a thioesters by negative ion fast-atom bombardment mass spectrometry and tandem mass spectrometry.

Zirrolli JA, Wheelan P, Murphy RC.

J Am Soc Mass Spectrom. 1994 May;5(5):416-24. doi: 10.1016/1044-0305(94)85057-7.

PMID:
24222596
13.

Metabolism of leukotriene B4 by cultured human keratinocytes. Formation of glutathione conjugates and dihydro metabolites.

Wheelan P, Zirrolli JA, Morelli JG, Murphy RC.

J Biol Chem. 1993 Dec 5;268(34):25439-48.

14.

Erratum to: Low-energy tandem mass spectrometry of the molecular ion derived from fatty acid methyl esters: A novel method for analysis of branched-chain fatty acids.

Zirrolli JA, Murphy RC.

J Am Soc Mass Spectrom. 1993 Oct;4(10):834. doi: 10.1016/1044-0305(93)80046-2. No abstract available.

PMID:
24227470
15.

Low-energy fast atom bombardment tandem mass spectrometry of monohydroxy substituted unsaturated fatty acids.

Wheelan P, Zirrolli JA, Murphy RC.

Biol Mass Spectrom. 1993 Aug;22(8):465-73.

PMID:
8357860
16.

Low-energy tandem mass spectrometry of the molecular ion derived from fatty acid methyl esters: A novel method for analysis of branched-chain fatty acids.

Zirrolli JA, Murphy RC.

J Am Soc Mass Spectrom. 1993 Mar;4(3):223-9. doi: 10.1016/1044-0305(93)85085-C.

PMID:
24234851
17.

Collision-induced dissociation of carboxylate anions from derivatized 5-lipoxygenase metabolites of arachidonic acid.

Fruteau de Laclos B, Zirrolli JA, Murphy RC.

Biol Mass Spectrom. 1993 Jan;22(1):9-18.

PMID:
8381676
19.
20.
21.
22.

Metabolism of 12(R)-hydroxy-5,8,10,14-eicosatetraenoic acid (12(R)-HETE) in corneal tissues: formation of novel metabolites.

Nishimura M, Schwartzman ML, Falck JR, Lumin S, Zirrolli JA, Murphy RC.

Arch Biochem Biophys. 1991 Nov 1;290(2):326-35.

PMID:
1929401
23.

Negative ion tandem mass spectrometry of leukotriene E4, and LTE 4, metabolites: Identification of LTE 4, in human urine.

Sala A, Kayganich K, Zirrolli JA, Murphy RC.

J Am Soc Mass Spectrom. 1991 Aug;2(4):314-21. doi: 10.1016/1044-0305(91)80023-Z.

PMID:
24242351
24.

Fast atom bombardment and collision-induced dissociation of prostaglandins and thromboxanes: Some examples of charge remote fragmentation.

Zirrolli JA, Davoli E, Bettazzoli L, Gross M, Murphy RC.

J Am Soc Mass Spectrom. 1990 Jul;1(4):325-35. doi: 10.1016/1044-0305(90)85009-B.

PMID:
24248827
25.

Incorporation of arachidonic acid into glycerophospholipids of a murine bone marrow derived mast cell.

Bettazzoli L, Zirrolli JA, Reidhead CT, Shahgholi M, Murphy RC.

Adv Prostaglandin Thromboxane Leukot Res. 1990;20:71-8. No abstract available.

PMID:
2169185
26.

Platelet-activating factor and leukotriene biosynthesis in whole blood. A model for the study of transcellular arachidonate metabolism.

Fradin A, Zirrolli JA, Maclouf J, Vausbinder L, Henson PM, Murphy RC.

J Immunol. 1989 Dec 1;143(11):3680-5.

PMID:
2555415
27.
28.

In vivo formation of beta-oxidized metabolites of leukotriene E4 in the rat.

Perrin P, Zirrolli J, Stene DO, Lellouche JP, Beaucourt JP, Murphy RC.

Prostaglandins. 1989 Jan;37(1):53-60.

PMID:
2541469
29.
30.

12(R)-hydroxyeicosatrienoic acid: a vasodilator cytochrome P-450-dependent arachidonate metabolite from the bovine corneal epithelium.

Murphy RC, Falck JR, Lumin S, Yadagiri P, Zirrolli JA, Balazy M, Masferrer JL, Abraham NG, Schwartzman ML.

J Biol Chem. 1988 Nov 15;263(32):17197-202.

31.

Labetalol is metabolized oxidatively in humans.

Gal J, Zirrolli JA, Lichtenstein PS.

Res Commun Chem Pathol Pharmacol. 1988 Oct;62(1):3-17.

PMID:
3205978
32.

Leukotriene inhibitors attenuate rat lung injury induced by hydrogen peroxide.

Burghuber OC, Strife RJ, Zirrolli J, Henson PM, Henson JE, Mathias MM, Reeves JT, Murphy RC, Voelkel NF.

Am Rev Respir Dis. 1985 May;131(5):778-85.

PMID:
3923881
33.

Leukotriene C4 production during hypoxic pulmonary vasoconstriction in isolated rat lungs.

Morganroth ML, Stenmark KR, Zirrolli JA, Mauldin R, Mathias M, Reeves JT, Murphy RC, Voelkel NF.

Prostaglandins. 1984 Dec;28(6):867-75.

PMID:
6522621
34.

Ethylenediaminetetraacetic acid in liquid chromatography of leukotrienes.

Anderson FS, Westcott JY, Zirrolli JA, Murphy RC.

Anal Chem. 1983 Sep;55(11):1837-9. No abstract available.

PMID:
6314847

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