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Items: 1 to 50 of 98

1.

Dysregulation of the Mitochondrial Proteome Occurs in Mice Lacking Adiponectin Receptor 1.

Pepin ME, Koentges C, Pfeil K, Gollmer J, Kersting S, Wiese S, Hoffmann MM, Odening KE, von Zur Mühlen C, Diehl P, Stachon P, Wolf D, Wende AR, Bode C, Zirlik A, Bugger H.

Front Endocrinol (Lausanne). 2019 Dec 13;10:872. doi: 10.3389/fendo.2019.00872. eCollection 2019.

2.

HDAC inhibition improves cardiopulmonary function in a feline model of diastolic dysfunction.

Wallner M, Eaton DM, Berretta RM, Liesinger L, Schittmayer M, Gindlhuber J, Wu J, Jeong MY, Lin YH, Borghetti G, Baker ST, Zhao H, Pfleger J, Blass S, Rainer PP, von Lewinski D, Bugger H, Mohsin S, Graier WF, Zirlik A, McKinsey TA, Birner-Gruenberger R, Wolfson MR, Houser SR.

Sci Transl Med. 2020 Jan 8;12(525). pii: eaay7205. doi: 10.1126/scitranslmed.aay7205.

PMID:
31915304
3.

Position Paper on Lipid Therapy in Patients with Diabetes Mellitus.

Parhofer KG, Birkenfeld AL, Krone W, Lehrke M, Marx N, Merkel M, Schütt KS, Zirlik A, Müller-Wieland D.

Exp Clin Endocrinol Diabetes. 2019 Dec;127(S 01):S97-S101. doi: 10.1055/a-1018-9228. Epub 2019 Dec 20. No abstract available.

PMID:
31860929
4.

Glucose lowering by SGLT2-inhibitor empagliflozin accelerates atherosclerosis regression in hyperglycemic STZ-diabetic mice.

Pennig J, Scherrer P, Gissler MC, Anto-Michel N, Hoppe N, Füner L, Härdtner C, Stachon P, Wolf D, Hilgendorf I, Mullick A, Bode C, Zirlik A, Goldberg IJ, Willecke F.

Sci Rep. 2019 Nov 29;9(1):17937. doi: 10.1038/s41598-019-54224-9.

5.

Publisher Correction: Real-time magnetic resonance imaging - guided coronary intervention in a porcine model.

Heidt T, Reiss S, Krafft AJ, Özen AC, Lottner T, Hehrlein C, Galmbacher R, Kayser G, Hilgendorf I, Stachon P, Wolf D, Zirlik A, Düring K, Zehender M, Meckel S, von Elverfeldt D, Bode C, Bock M, von Zur Mühlen C.

Sci Rep. 2019 Nov 29;9(1):18282. doi: 10.1038/s41598-019-54947-9.

6.

Inflammation in acute coronary syndrome: Expression of TLR2 mRNA is increased in platelets of patients with ACS.

Heger LA, Hortmann M, Albrecht M, Colberg C, Peter K, Witsch T, Stallmann D, Zirlik A, Bode C, Duerschmied D, Ahrens I.

PLoS One. 2019 Oct 23;14(10):e0224181. doi: 10.1371/journal.pone.0224181. eCollection 2019.

7.

Association of soluble CD40L with short-term and long-term cardiovascular and all-cause mortality: The Ludwigshafen Risk and Cardiovascular Health (LURIC) study.

Gergei I, Kälsch T, Scharnagl H, Kleber ME, Zirlik A, März W, Krämer BK, Kälsch AI.

Atherosclerosis. 2019 Dec;291:127-131. doi: 10.1016/j.atherosclerosis.2019.09.004. Epub 2019 Sep 14.

PMID:
31558283
8.

Predictors of survival in patients with acute coronary syndrome undergoing percutaneous coronary intervention of unprotected left main coronary artery stenosis.

Staudacher DL, Schmitt C, Zirlik A, Zehender M, Stachon P, Bothe W, Zotzmann V, Bode C, von Zur Muehlen C.

Catheter Cardiovasc Interv. 2019 Sep 11. doi: 10.1002/ccd.28495. [Epub ahead of print]

PMID:
31512392
9.

Tumor Necrosis Factor Receptor-Associated Factor 5 Promotes Arterial Neointima Formation through Smooth Muscle Cell Proliferation.

Willecke F, Rupprecht B, Gissler MC, Pfeiffer K, Anto-Michel N, Stachon P, Wolf D, Hilgendorf I, Hoppe N, Bode C, Zirlik A.

J Vasc Res. 2019;56(6):308-319. doi: 10.1159/000501615. Epub 2019 Aug 22.

PMID:
31437850
10.

The association of high-normal international-normalized-ratio (INR) with mortality in patients referred for coronary angiography.

Delgado GE, Zirlik A, Gruber R, Scheffold T, Krämer BK, März W, Kleber ME.

PLoS One. 2019 Aug 15;14(8):e0221112. doi: 10.1371/journal.pone.0221112. eCollection 2019.

11.

Blood pressure changes after renal denervation are more pronounced in women and nondiabetic patients: findings from the Austrian Transcatheter Renal Denervation Registry.

Zweiker D, Lambert T, Steinwender C, Weber T, Suppan M, Brussee H, Niederl E, Koppelstaetter C, Kerschbaum J, Watschinger B, Hohenstein-Scheibenecker K, Reindl-Schwaighofer R, Sturmberger T, Kindslehner C, Weiss TW, Rohla M, Gruener P, Maister P, Auer J, Dechant C, Sykora J, Krismer C, Glaser S, Zirlik A, Zweiker R.

J Hypertens. 2019 Nov;37(11):2290-2297. doi: 10.1097/HJH.0000000000002190.

PMID:
31335512
12.

Residual inflammatory risk in coronary heart disease: incidence of elevated high-sensitive CRP in a real-world cohort.

Peikert A, Kaier K, Merz J, Manhart L, Schäfer I, Hilgendorf I, Hehn P, Wolf D, Willecke F, Sheng X, Clemens A, Zehender M, von Zur Mühlen C, Bode C, Zirlik A, Stachon P.

Clin Res Cardiol. 2019 Jul 19. doi: 10.1007/s00392-019-01511-0. [Epub ahead of print]

PMID:
31325043
13.

Real-time magnetic resonance imaging - guided coronary intervention in a porcine model.

Heidt T, Reiss S, Krafft AJ, Özen AC, Lottner T, Hehrlein C, Galmbacher R, Kayser G, Hilgendorf I, Stachon P, Wolf D, Zirlik A, Düring K, Zehender M, Meckel S, von Elverfeldt D, Bode C, Bock M, von Zur Mühlen C.

Sci Rep. 2019 Jun 17;9(1):8663. doi: 10.1038/s41598-019-45154-7. Erratum in: Sci Rep. 2019 Nov 29;9(1):18282.

14.

Impaired SIRT3 activity mediates cardiac dysfunction in endotoxemia by calpain-dependent disruption of ATP synthesis.

Koentges C, Cimolai MC, Pfeil K, Wolf D, Marchini T, Tarkhnishvili A, Hoffmann MM, Odening KE, Diehl P, von Zur Mühlen C, Alvarez S, Bode C, Zirlik A, Bugger H.

J Mol Cell Cardiol. 2019 Aug;133:138-147. doi: 10.1016/j.yjmcc.2019.06.008. Epub 2019 Jun 13.

PMID:
31201798
15.

Nationwide outcomes of aortic valve replacement for pure aortic regurgitation in Germany 2008-2015.

Stachon P, Kaier K, Heidt T, Bothe W, Zirlik A, Zehender M, Bode C, von Zur Mühlen C.

Catheter Cardiovasc Interv. 2019 Jun 4. doi: 10.1002/ccd.28361. [Epub ahead of print]

PMID:
31165569
16.

Risk-Adjusted Comparison of In-Hospital Outcomes of Transcatheter and Surgical Aortic Valve Replacement.

Stachon P, Kaier K, Zirlik A, Bothe W, Heidt T, Zehender M, Bode C, von Zur Mühlen C.

J Am Heart Assoc. 2019 Apr 2;8(7):e011504. doi: 10.1161/JAHA.118.011504.

17.

Severe eosinophilic myocarditis associated with modafinil in a patient with normal peripheral eosinophil count.

Bäuml M, Udi J, Klingel K, Bode C, Warnatz K, Zirlik A, Duerschmied D, Biever P.

Clin Res Cardiol. 2019 Aug;108(8):963-966. doi: 10.1007/s00392-019-01434-w. Epub 2019 Feb 12. No abstract available.

PMID:
30756153
18.

Estimating the additional costs per life saved due to transcatheter aortic valve replacement: a secondary data analysis of electronic health records in Germany.

Kaier K, von Zur Mühlen C, Zirlik A, Bothe W, Hehn P, Zehender M, Bode C, Stachon P.

Eur J Health Econ. 2019 Jun;20(4):625-632. doi: 10.1007/s10198-018-1023-x. Epub 2019 Jan 2.

PMID:
30600467
19.

[Development and Results of Transcatheter and Surgical Aortic Valve Replacement in Germany 2014 and 2015].

Stachon P, Kaier K, Zirlik A, Bothe W, Zehender M, Bode C, von Zur Mühlen C.

Dtsch Med Wochenschr. 2018 Nov;143(23):e206-e212. doi: 10.1055/a-0655-6218. Epub 2018 Nov 15. German.

PMID:
30440067
20.

Purinergic receptor Y2 (P2Y2)- dependent VCAM-1 expression promotes immune cell infiltration in metabolic syndrome.

Merz J, Albrecht P, von Garlen S, Ahmed I, Dimanski D, Wolf D, Hilgendorf I, Härdtner C, Grotius K, Willecke F, Heidt T, Bugger H, Hoppe N, Kintscher U, von Zur Mühlen C, Idzko M, Bode C, Zirlik A, Stachon P.

Basic Res Cardiol. 2018 Oct 18;113(6):45. doi: 10.1007/s00395-018-0702-1.

PMID:
30338362
21.

Sex-Specific Differences in Outcome of Transcatheter or Surgical Aortic Valve Replacement.

Kaier K, von Zur Mühlen C, Zirlik A, Schmoor C, Roth K, Bothe W, Hehn P, Reinöhl J, Zehender M, Bode C, Stachon P.

Can J Cardiol. 2018 Aug;34(8):992-998. doi: 10.1016/j.cjca.2018.04.009. Epub 2018 Apr 12.

PMID:
30056851
22.

Risk factors and outcome of postoperative delirium after transcatheter aortic valve replacement.

Stachon P, Kaier K, Zirlik A, Reinöhl J, Heidt T, Bothe W, Hehn P, Zehender M, Bode C, von Zur Mühlen C.

Clin Res Cardiol. 2018 Sep;107(9):756-762. doi: 10.1007/s00392-018-1241-3. Epub 2018 Apr 13.

PMID:
29654435
23.

Atlas of the Immune Cell Repertoire in Mouse Atherosclerosis Defined by Single-Cell RNA-Sequencing and Mass Cytometry.

Winkels H, Ehinger E, Vassallo M, Buscher K, Dinh HQ, Kobiyama K, Hamers AAJ, Cochain C, Vafadarnejad E, Saliba AE, Zernecke A, Pramod AB, Ghosh AK, Anto Michel N, Hoppe N, Hilgendorf I, Zirlik A, Hedrick CC, Ley K, Wolf D.

Circ Res. 2018 Jun 8;122(12):1675-1688. doi: 10.1161/CIRCRESAHA.117.312513. Epub 2018 Mar 15.

24.

A ligand-specific blockade of the integrin Mac-1 selectively targets pathologic inflammation while maintaining protective host-defense.

Wolf D, Anto-Michel N, Blankenbach H, Wiedemann A, Buscher K, Hohmann JD, Lim B, Bäuml M, Marki A, Mauler M, Duerschmied D, Fan Z, Winkels H, Sidler D, Diehl P, Zajonc DM, Hilgendorf I, Stachon P, Marchini T, Willecke F, Schell M, Sommer B, von Zur Muhlen C, Reinöhl J, Gerhardt T, Plow EF, Yakubenko V, Libby P, Bode C, Ley K, Peter K, Zirlik A.

Nat Commun. 2018 Feb 6;9(1):525. doi: 10.1038/s41467-018-02896-8.

25.

Coronary magnetic resonance imaging after routine implantation of bioresorbable vascular scaffolds allows non-invasive evaluation of vascular patency.

von Zur Mühlen C, Reiss S, Krafft AJ, Besch L, Menza M, Zehender M, Heidt T, Maier A, Pfannebecker T, Zirlik A, Reinöhl J, Stachon P, Hilgendorf I, Wolf D, Diehl P, Wengenmayer T, Ahrens I, Bode C, Bock M.

PLoS One. 2018 Jan 25;13(1):e0191413. doi: 10.1371/journal.pone.0191413. eCollection 2018.

26.

Inflammatory Pathways Regulated by Tumor Necrosis Receptor-Associated Factor 1 Protect From Metabolic Consequences in Diet-Induced Obesity.

Anto Michel N, Colberg C, Buscher K, Sommer B, Pramod AB, Ehinger E, Dufner B, Hoppe N, Pfeiffer K, Marchini T, Willecke F, Stachon P, Hilgendorf I, Heidt T, von Zur Muhlen C, von Elverfeldt D, Pfeifer D, Schüle R, Kintscher U, Brachs S, Ley K, Bode C, Zirlik A, Wolf D.

Circ Res. 2018 Mar 2;122(5):693-700. doi: 10.1161/CIRCRESAHA.117.312055. Epub 2018 Jan 22.

27.

Novel Reversible Model of Atherosclerosis and Regression Using Oligonucleotide Regulation of the LDL Receptor.

Basu D, Hu Y, Huggins LA, Mullick AE, Graham MJ, Wietecha T, Barnhart S, Mogul A, Pfeiffer K, Zirlik A, Fisher EA, Bornfeldt KE, Willecke F, Goldberg IJ.

Circ Res. 2018 Feb 16;122(4):560-567. doi: 10.1161/CIRCRESAHA.117.311361. Epub 2018 Jan 10.

28.

Gene expression analysis to identify mechanisms underlying heart failure susceptibility in mice and humans.

Koentges C, Pepin ME, Müsse C, Pfeil K, Alvarez SVV, Hoppe N, Hoffmann MM, Odening KE, Sossalla S, Zirlik A, Hein L, Bode C, Wende AR, Bugger H.

Basic Res Cardiol. 2017 Dec 29;113(1):8. doi: 10.1007/s00395-017-0666-6. Print 2018 Jan 8.

29.

A molecular intravascular ultrasound contrast agent allows detection of activated platelets on the surface of symptomatic human plaques.

Maier A, Plaza-Heck P, Meixner F, Guenther F, Kaufmann BA, Kramer M, Heidt T, Zirlik A, Hilgendorf I, Reinöhl J, Stachon P, Bronsert P, Birkemeyer R, Neudorfer I, Peter K, Bode C, von Zur Mühlen C.

Atherosclerosis. 2017 Dec;267:68-77. doi: 10.1016/j.atherosclerosis.2017.10.029. Epub 2017 Oct 24.

PMID:
29101838
30.

Dual targeting improves capture of ultrasound microbubbles towards activated platelets but yields no additional benefit for imaging of arterial thrombosis.

Günther F, Heidt T, Kramer M, Khanicheh E, Klibanov AL, Geibel-Zehender A, Ferrante EA, Hilgendorf I, Wolf D, Zirlik A, Reinöhl J, Bode C, Peter K, Kaufmann BA, Mühlen CVZ.

Sci Rep. 2017 Nov 2;7(1):14898. doi: 10.1038/s41598-017-15080-7.

31.

CD40L and Its Receptors in Atherothrombosis-An Update.

Michel NA, Zirlik A, Wolf D.

Front Cardiovasc Med. 2017 Jun 20;4:40. doi: 10.3389/fcvm.2017.00040. eCollection 2017. Review.

32.

Impact of pulmonary hypertension on in-hospital outcome after surgical or transcatheter aortic valve replacement.

Gutmann A, Kaier K, Reinecke H, Frankenstein L, Zirlik A, Bothe W, von Zur Mühlen C, Zehender M, Reinöhl J, Bode C, Stachon P.

EuroIntervention. 2017 Sep 20;13(7):804-810. doi: 10.4244/EIJ-D-16-00927.

33.

P2X7 Deficiency Blocks Lesional Inflammasome Activity and Ameliorates Atherosclerosis in Mice.

Stachon P, Heidenreich A, Merz J, Hilgendorf I, Wolf D, Willecke F, von Garlen S, Albrecht P, Härdtner C, Ehrat N, Hoppe N, Reinöhl J, von Zur Mühlen C, Bode C, Idzko M, Zirlik A.

Circulation. 2017 Jun 20;135(25):2524-2533. doi: 10.1161/CIRCULATIONAHA.117.027400. Epub 2017 Apr 4.

PMID:
28377486
34.

Learning Curves Among All Patients Undergoing Transcatheter Aortic Valve Implantation in Germany: A Retrospective Observational Study.

Kaier K, Reinecke H, Schmoor C, Frankenstein L, Vach W, Hehn P, Zirlik A, Bode C, Zehender M, Reinöhl J.

Int J Cardiol. 2017 May 15;235:17-21. doi: 10.1016/j.ijcard.2017.02.138. Epub 2017 Mar 2.

PMID:
28274581
35.

Towards a cardiac allocation score: a retrospective calculation for 73 patients from a German transplant center.

Claes S, Berchtold-Herz M, Zhou Q, Trummer G, Bock M, Zirlik A, Beyersdorf F, Bode C, Grundmann S.

J Cardiothorac Surg. 2017 Mar 7;12(1):14. doi: 10.1186/s13019-017-0575-7.

36.

The impact of post-procedural complications on reimbursement, length of stay and mechanical ventilation among patients undergoing transcatheter aortic valve implantation in Germany.

Kaier K, Reinecke H, Naci H, Frankenstein L, Bode M, Vach W, Hehn P, Zirlik A, Zehender M, Reinöhl J.

Eur J Health Econ. 2018 Mar;19(2):223-228. doi: 10.1007/s10198-017-0877-7. Epub 2017 Feb 22.

PMID:
28229254
37.
38.

Inflammation, but not recruitment, of adipose tissue macrophages requires signalling through Mac-1 (CD11b/CD18) in diet-induced obesity (DIO).

Wolf D, Bukosza N, Engel D, Poggi M, Jehle F, Anto Michel N, Chen YC, Colberg C, Hoppe N, Dufner B, Boon L, Blankenbach H, Hilgendorf I, von Zur Muhlen C, Reinöhl J, Sommer B, Marchini T, Febbraio MA, Weber C, Bode C, Peter K, Lutgens E, Zirlik A.

Thromb Haemost. 2017 Jan 26;117(2):325-338. doi: 10.1160/TH16-07-0553. Epub 2016 Nov 17.

PMID:
27853810
39.

Renal denervation reduces office and ambulatory heart rate in patients with uncontrolled hypertension: 12-month outcomes from the global SYMPLICITY registry.

Böhm M, Ukena C, Ewen S, Linz D, Zivanovic I, Hoppe U, Narkiewicz K, Ruilope L, Schlaich M, Negoita M, Schmieder R, Williams B, Zeymer U, Zirlik A, Mancia G, Mahfoud F; Global SYMPLICITY Registry Investigators.

J Hypertens. 2016 Dec;34(12):2480-2486.

PMID:
27755390
40.

Transcatheter Aortic Valve Replacement: The New Standard in Patients With Previous Coronary Bypass Grafting?

Reinöhl J, Kaier K, Reinecke H, Frankenstein L, Zirlik A, Zehender M, von Zur Mühlen C, Bode C, Stachon P.

JACC Cardiovasc Interv. 2016 Oct 24;9(20):2137-2143. doi: 10.1016/j.jcin.2016.07.035.

41.

Extracellular ATP Induces Vascular Inflammation and Atherosclerosis via Purinergic Receptor Y2 in Mice.

Stachon P, Geis S, Peikert A, Heidenreich A, Michel NA, Ünal F, Hoppe N, Dufner B, Schulte L, Marchini T, Cicko S, Ayata K, Zech A, Wolf D, Hilgendorf I, Willecke F, Reinöhl J, von Zur Mühlen C, Bode C, Idzko M, Zirlik A.

Arterioscler Thromb Vasc Biol. 2016 Aug;36(8):1577-86. doi: 10.1161/ATVBAHA.115.307397. Epub 2016 Jun 23.

PMID:
27339459
42.

Acute exposure to air pollution particulate matter aggravates experimental myocardial infarction in mice by potentiating cytokine secretion from lung macrophages.

Marchini T, Wolf D, Michel NA, Mauler M, Dufner B, Hoppe N, Beckert J, Jäckel M, Magnani N, Duerschmied D, Tasat D, Alvarez S, Reinöhl J, von Zur Muhlen C, Idzko M, Bode C, Hilgendorf I, Evelson P, Zirlik A.

Basic Res Cardiol. 2016 Jul;111(4):44. doi: 10.1007/s00395-016-0562-5. Epub 2016 May 30.

43.

Molecular Imaging of Activated Platelets Allows the Detection of Pulmonary Embolism with Magnetic Resonance Imaging.

Heidt T, Ehrismann S, Hövener JB, Neudorfer I, Hilgendorf I, Reisert M, Hagemeyer CE, Zirlik A, Reinöhl J, Bode C, Peter K, von Elverfeldt D, von Zur Muhlen C.

Sci Rep. 2016 May 3;6:25044. doi: 10.1038/srep25044.

44.

Urine proteome analysis as a discovery tool in patients with deep vein thrombosis and pulmonary embolism.

von Zur Mühlen C, Koeck T, Schiffer E, Sackmann C, Zürbig P, Hilgendorf I, Reinöhl J, Rivera J, Zirlik A, Hehrlein C, Mischak H, Bode C, Peter K.

Proteomics Clin Appl. 2016 May;10(5):574-84. doi: 10.1002/prca.201500105. Epub 2016 Apr 4.

PMID:
26898369
45.

Atheroprotection through SYK inhibition fails in established disease when local macrophage proliferation dominates lesion progression.

Lindau A, Härdtner C, Hergeth SP, Blanz KD, Dufner B, Hoppe N, Anto-Michel N, Kornemann J, Zou J, Gerhardt LM, Heidt T, Willecke F, Geis S, Stachon P, Wolf D, Libby P, Swirski FK, Robbins CS, McPheat W, Hawley S, Braddock M, Gilsbach R, Hein L, von zur Mühlen C, Bode C, Zirlik A, Hilgendorf I.

Basic Res Cardiol. 2016 Mar;111(2):20. doi: 10.1007/s00395-016-0535-8. Epub 2016 Feb 18.

46.

Asymptomatic atrial fibrillation and risk of stroke.

Stachon P, Ahrens I, Faber T, Bode C, Zirlik A.

Panminerva Med. 2015 Dec;57(4):211-5. Epub 2016 Jan 12. Review.

47.

Dual pathway therapy in acute coronary syndrome.

Stachon P, Ahrens I, Bode C, Zirlik A.

J Thromb Thrombolysis. 2016 Aug;42(2):254-60. doi: 10.1007/s11239-015-1306-3. Review.

PMID:
26660521
48.

Aortic root volume is associated with contained rupture of the aortic annulus in balloon-expandable transcatheter aortic valve replacement.

Reinöhl J, Psyrakis D, Kaier K, Kodirov S, Siepe M, Gutmann A, von zur Mühlen C, Moser M, Ahrens I, Pache G, Zirlik A, Langer M, Beyersdorf F, Zehender M, Bode C, Blanke P.

Catheter Cardiovasc Interv. 2016 Mar;87(4):807-17. doi: 10.1002/ccd.26260. Epub 2015 Oct 26.

PMID:
26501403
49.

In-hospital resource utilization in surgical and transcatheter aortic valve replacement.

Reinöhl J, Kaier K, Gutmann A, Sorg S, von Zur Mühlen C, Siepe M, Baumbach H, Moser M, Geibel A, Zirlik A, Blanke P, Vach W, Beyersdorf F, Bode C, Zehender M.

BMC Cardiovasc Disord. 2015 Oct 22;15:132. doi: 10.1186/s12872-015-0118-x.

50.

Influence of effective noninvasive positive pressure ventilation on inflammatory and cardiovascular biomarkers in stable hypercapnic COPD patients.

Dreher M, Schulte L, Müller T, Ekkernkamp E, Zirlik A.

Respir Med. 2015 Oct;109(10):1300-4. doi: 10.1016/j.rmed.2015.08.004. Epub 2015 Aug 13.

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