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Items: 44

1.

Intestinal Metaproteomics Reveals Host-Microbiota Interactions in Subjects at Risk for Type 1 Diabetes.

Gavin PG, Mullaney JA, Loo D, Cao KL, Gottlieb PA, Hill MM, Zipris D, Hamilton-Williams EE.

Diabetes Care. 2018 Oct;41(10):2178-2186. doi: 10.2337/dc18-0777. Epub 2018 Aug 12.

2.

Involvement of adipose tissue inflammation and dysfunction in virus-induced type 1 diabetes.

Needell JC, Brown MN, Zipris D.

J Endocrinol. 2018 Jul;238(1):61-75. doi: 10.1530/JOE-18-0131. Epub 2018 May 9.

PMID:
29743341
3.

Targeting Innate Immunity for Type 1 Diabetes Prevention.

Needell JC, Zipris D.

Curr Diab Rep. 2017 Sep 27;17(11):113. doi: 10.1007/s11892-017-0930-z. Review.

PMID:
28956297
4.

Maternal treatment with short-chain fatty acids modulates the intestinal microbiota and immunity and ameliorates type 1 diabetes in the offspring.

Needell JC, Ir D, Robertson CE, Kroehl ME, Frank DN, Zipris D.

PLoS One. 2017 Sep 8;12(9):e0183786. doi: 10.1371/journal.pone.0183786. eCollection 2017.

5.

Implication of the intestinal microbiome as a potential surrogate marker of immune responsiveness to experimental therapies in autoimmune diabetes.

Needell JC, Dinarello CA, Ir D, Robertson CE, Ryan SM, Kroehl ME, Frank DN, Zipris D.

PLoS One. 2017 Mar 16;12(3):e0173968. doi: 10.1371/journal.pone.0173968. eCollection 2017.

6.

The Role of the Intestinal Microbiome in Type 1 Diabetes Pathogenesis.

Needell JC, Zipris D.

Curr Diab Rep. 2016 Oct;16(10):89. doi: 10.1007/s11892-016-0781-z. Review.

PMID:
27523648
7.

Response to Comment on Alkanani et al. Alterations in Intestinal Microbiota Correlate With Susceptibility to Type 1 Diabetes. Diabetes 2015;64:3510-3520.

Wagner BD, Frank DN, Zipris D.

Diabetes. 2015 Oct;64(10):e41. doi: 10.2337/dbi15-0009. No abstract available.

8.

Alterations in Intestinal Microbiota Correlate With Susceptibility to Type 1 Diabetes.

Alkanani AK, Hara N, Gottlieb PA, Ir D, Robertson CE, Wagner BD, Frank DN, Zipris D.

Diabetes. 2015 Oct;64(10):3510-20. doi: 10.2337/db14-1847. Epub 2015 Jun 11.

9.

RNase L contributes to experimentally induced type 1 diabetes onset in mice.

Zeng C, Yi X, Zipris D, Liu H, Zhang L, Zheng Q, Malathi K, Jin G, Zhou A.

J Endocrinol. 2014 Dec;223(3):277-87. doi: 10.1530/JOE-14-0509. Epub 2014 Oct 6.

10.

Kilham Rat Virus-induced type 1 diabetes involves beta cell infection and intra-islet JAK-STAT activation prior to insulitis.

Alkanani AK, Hara N, Gianani R, Zipris D.

Virology. 2014 Nov;468-470:19-27. doi: 10.1016/j.virol.2014.07.041. Epub 2014 Aug 16.

11.

α1-Antitrypsin therapy downregulates toll-like receptor-induced IL-1β responses in monocytes and myeloid dendritic cells and may improve islet function in recently diagnosed patients with type 1 diabetes.

Gottlieb PA, Alkanani AK, Michels AW, Lewis EC, Shapiro L, Dinarello CA, Zipris D.

J Clin Endocrinol Metab. 2014 Aug;99(8):E1418-26. doi: 10.1210/jc.2013-3864. Epub 2014 Feb 14.

12.

Induction of diabetes in the RIP-B7.1 mouse model is critically dependent on TLR3 and MyD88 pathways and is associated with alterations in the intestinal microbiome.

Alkanani AK, Hara N, Lien E, Ir D, Kotter CV, Robertson CE, Wagner BD, Frank DN, Zipris D.

Diabetes. 2014 Feb;63(2):619-31. doi: 10.2337/db13-1007. Epub 2013 Dec 18.

13.

Modulation of virus-induced innate immunity and type 1 diabetes by IL-1 blockade.

Hara N, Alkanani AK, Dinarello CA, Zipris D.

Innate Immun. 2014 Aug;20(6):574-84. doi: 10.1177/1753425913502242. Epub 2013 Sep 23.

PMID:
24062197
14.

Histone deacetylase inhibitor suppresses virus-induced proinflammatory responses and type 1 diabetes.

Hara N, Alkanani AK, Dinarello CA, Zipris D.

J Mol Med (Berl). 2014 Jan;92(1):93-102. doi: 10.1007/s00109-013-1078-1. Epub 2013 Aug 28.

PMID:
23982318
15.

The interplay between the gut microbiota and the immune system in the mechanism of type 1 diabetes.

Zipris D.

Curr Opin Endocrinol Diabetes Obes. 2013 Aug;20(4):265-70. doi: 10.1097/MED.0b013e3283628569. Review.

PMID:
23743644
16.

The role of the intestinal microbiota in type 1 diabetes.

Hara N, Alkanani AK, Ir D, Robertson CE, Wagner BD, Frank DN, Zipris D.

Clin Immunol. 2013 Feb;146(2):112-9. doi: 10.1016/j.clim.2012.12.001. Epub 2012 Dec 11. Review.

PMID:
23314185
17.

Prevention of virus-induced type 1 diabetes with antibiotic therapy.

Hara N, Alkanani AK, Ir D, Robertson CE, Wagner BD, Frank DN, Zipris D.

J Immunol. 2012 Oct 15;189(8):3805-14. doi: 10.4049/jimmunol.1201257. Epub 2012 Sep 17. Erratum in: J Immunol. 2012 Dec 15;189(12):5995.

18.

Dysregulated Toll-like receptor-induced interleukin-1β and interleukin-6 responses in subjects at risk for the development of type 1 diabetes.

Alkanani AK, Rewers M, Dong F, Waugh K, Gottlieb PA, Zipris D.

Diabetes. 2012 Oct;61(10):2525-33. Epub 2012 Jun 29.

19.

Innate immunity in type 1 diabetes.

Zipris D.

Diabetes Metab Res Rev. 2011 Nov;27(8):824-9. doi: 10.1002/dmrr.1256.

PMID:
22069267
20.

Altered Toll-like receptor signaling pathways in human type 1 diabetes.

Meyers AJ, Shah RR, Gottlieb PA, Zipris D.

J Mol Med (Berl). 2010 Dec;88(12):1221-31. doi: 10.1007/s00109-010-0666-6. Epub 2010 Aug 20.

PMID:
20725710
21.

Toll-like receptors and type 1 diabetes.

Zipris D.

Adv Exp Med Biol. 2010;654:585-610. doi: 10.1007/978-90-481-3271-3_25. Review.

PMID:
20217515
22.

Brief dexamethasone treatment during acute infection prevents virus-induced autoimmune diabetes.

Londono P, Komura A, Hara N, Zipris D.

Clin Immunol. 2010 Jun;135(3):401-11. doi: 10.1016/j.clim.2010.01.007. Epub 2010 Feb 18.

PMID:
20167539
23.

DNA microarray analysis for the identification of innate immune pathways implicated in virus-induced autoimmune diabetes.

Wolter TR, Wong R, Sarkar SA, Zipris D.

Clin Immunol. 2009 Jul;132(1):103-15. doi: 10.1016/j.clim.2009.02.007. Epub 2009 Mar 26.

PMID:
19328037
24.

The role of Toll-like receptor pathways in the mechanism of type 1 diabetes.

Lien E, Zipris D.

Curr Mol Med. 2009 Feb;9(1):52-68. Review.

PMID:
19199942
25.

Epidemiology of type 1 diabetes and what animal models teach us about the role of viruses in disease mechanisms.

Zipris D.

Clin Immunol. 2009 Apr;131(1):11-23. doi: 10.1016/j.clim.2008.12.011. Epub 2009 Jan 29. Review.

PMID:
19185542
26.

Innate immune pathways in virus-induced autoimmune diabetes.

Nair A, Wolter TR, Meyers AJ, Zipris D.

Ann N Y Acad Sci. 2008 Dec;1150:139-42. doi: 10.1196/annals.1447.004.

PMID:
19120282
27.

Closing the circle between the bedside and the bench: Toll-like receptors in models of virally induced diabetes.

Bortell R, Pino SC, Greiner DL, Zipris D, Rossini AA.

Ann N Y Acad Sci. 2008 Dec;1150:112-22. doi: 10.1196/annals.1447.025. Review.

28.

Innate immunity and its role in type 1 diabetes.

Zipris D.

Curr Opin Endocrinol Diabetes Obes. 2008 Aug;15(4):326-31. doi: 10.1097/MED.0b013e3283073a46. Review.

PMID:
18594272
29.

TLR9-signaling pathways are involved in Kilham rat virus-induced autoimmune diabetes in the biobreeding diabetes-resistant rat.

Zipris D, Lien E, Nair A, Xie JX, Greiner DL, Mordes JP, Rossini AA.

J Immunol. 2007 Jan 15;178(2):693-701.

30.

Costimulation and autoimmune diabetes in BB rats.

Beaudette-Zlatanova BC, Whalen B, Zipris D, Yagita H, Rozing J, Groen H, Benjamin CD, Hunig T, Drexhage HA, Ansari MJ, Leif J, Mordes JP, Greiner DL, Sayegh MH, Rossini AA.

Am J Transplant. 2006 May;6(5 Pt 1):894-902.

31.

TLR activation synergizes with Kilham rat virus infection to induce diabetes in BBDR rats.

Zipris D, Lien E, Xie JX, Greiner DL, Mordes JP, Rossini AA.

J Immunol. 2005 Jan 1;174(1):131-42.

32.

Infections that induce autoimmune diabetes in BBDR rats modulate CD4+CD25+ T cell populations.

Zipris D, Hillebrands JL, Welsh RM, Rozing J, Xie JX, Mordes JP, Greiner DL, Rossini AA.

J Immunol. 2003 Apr 1;170(7):3592-602.

34.

Fetal thymi from diabetes-prone but not diabetes-resistant BB/Wor rats fail to generate mature ART2+ T-cells in organ culture.

Zipris D, Leif J, Deluca D, Lin MY, Mordes JP, Rossini AA, Greiner DL, Whalen BJ.

Cell Mol Biol (Noisy-le-grand). 2001 Feb;47(1):65-74.

PMID:
11292261
35.

Expression in BALB/c and C57BL/6 mice of Rt6-1 and Rt6-2 ADP-ribosyltransferases that differ in enzymatic activity: C57BL/6 Rt6-1 is a natural transferase knockout.

Kanaitsuka T, Bortell R, Stevens LA, Moss J, Sardinha D, Rajan TV, Zipris D, Mordes JP, Greiner DL, Rossini AA.

J Immunol. 1997 Sep 15;159(6):2741-9.

PMID:
9300695
36.

The BB/Wor rat and the balance hypothesis of autoimmunity.

Mordes JP, Bortell R, Doukas J, Rigby M, Whalen B, Zipris D, Greiner DL, Rossini AA.

Diabetes Metab Rev. 1996 Jul;12(2):103-9. Review. No abstract available.

PMID:
8877279
38.
39.

Protection of mice against mycobacterial infection by lymphoid cell vaccination.

Levy L, Enk CD, Zipris D, Cohen IR.

Isr J Med Sci. 1994 Jan;30(1):22-5.

PMID:
8138393
40.

Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice.

Rapoport MJ, Jaramillo A, Zipris D, Lazarus AH, Serreze DV, Leiter EH, Cyopick P, Danska JS, Delovitch TL.

J Exp Med. 1993 Jul 1;178(1):87-99.

42.

Altered thymic and peripheral T-lymphocyte repertoire preceding onset of diabetes in NOD mice.

Zipris D, Crow AR, Delovitch TL.

Diabetes. 1991 Apr;40(4):429-35.

PMID:
1826279
44.

Interaction of lectins from gonads and haemolymph of the sea hare Aplysia with bacteria.

Zipris D, Gilboa-Garber N, Susswein AJ.

Microbios. 1986;46(188-189):193-8.

PMID:
3091995

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