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Items: 1 to 50 of 193

1.

Predicting the antistaphylococcal effects of daptomycin-rifampicin combinations in an in vitro dynamic model.

Golikova MV, Strukova EN, Portnoy YA, Zinner SH, Firsov AA.

J Antibiot (Tokyo). 2020 Feb;73(2):101-107. doi: 10.1038/s41429-019-0249-x. Epub 2019 Oct 17.

PMID:
31624338
2.

A novel parameter to predict the effects of antibiotic combinations on the development of Staphylococcus aureus resistance: in vitro model studies at subtherapeutic daptomycin and rifampicin exposures.

Golikova MV, Strukova EN, Portnoy YA, Dovzhenko SA, Kobrin MB, Zinner SH, Firsov AA.

J Chemother. 2019 Jul 17:1-9. doi: 10.1080/1120009X.2019.1640924. [Epub ahead of print]

PMID:
31314704
3.

Resistance studies with Streptococcus pneumoniae using an in vitro dynamic model: amoxicillin versus azithromycin at clinical exposures.

Golikova MV, Strukova EN, Portnoy YA, Dovzhenko SA, Kobrin MB, Zinner SH, Firsov AA.

J Chemother. 2019 Sep;31(5):252-260. doi: 10.1080/1120009X.2019.1623361. Epub 2019 Jun 8.

PMID:
31179907
4.

Profile of a Novel Anionic Fluoroquinolone-Delafloxacin.

Tulkens PM, Van Bambeke F, Zinner SH.

Clin Infect Dis. 2019 Apr 8;68(Supplement_3):S213-S222. doi: 10.1093/cid/ciy1079.

5.

Interrogating the Genetic Determinants of Tourette's Syndrome and Other Tic Disorders Through Genome-Wide Association Studies.

Yu D, Sul JH, Tsetsos F, Nawaz MS, Huang AY, Zelaya I, Illmann C, Osiecki L, Darrow SM, Hirschtritt ME, Greenberg E, Muller-Vahl KR, Stuhrmann M, Dion Y, Rouleau G, Aschauer H, Stamenkovic M, Schlögelhofer M, Sandor P, Barr CL, Grados M, Singer HS, Nöthen MM, Hebebrand J, Hinney A, King RA, Fernandez TV, Barta C, Tarnok Z, Nagy P, Depienne C, Worbe Y, Hartmann A, Budman CL, Rizzo R, Lyon GJ, McMahon WM, Batterson JR, Cath DC, Malaty IA, Okun MS, Berlin C, Woods DW, Lee PC, Jankovic J, Robertson MM, Gilbert DL, Brown LW, Coffey BJ, Dietrich A, Hoekstra PJ, Kuperman S, Zinner SH, Luðvigsson P, Sæmundsen E, Thorarensen Ó, Atzmon G, Barzilai N, Wagner M, Moessner R, Ophoff R, Pato CN, Pato MT, Knowles JA, Roffman JL, Smoller JW, Buckner RL, Willsey AJ, Tischfield JA, Heiman GA, Stefansson H, Stefansson K, Posthuma D, Cox NJ, Pauls DL, Freimer NB, Neale BM, Davis LK, Paschou P, Coppola G, Mathews CA, Scharf JM; Tourette Association of America International Consortium for Genetics, the Gilles de la Tourette GWAS Replication Initiative, the Tourette International Collaborative Genetics Study, and the Psychiatric Genomics Consortium Tourette Syndrome Working Group.

Am J Psychiatry. 2019 Mar 1;176(3):217-227. doi: 10.1176/appi.ajp.2018.18070857.

PMID:
30818990
6.

Concentration-dependent enrichment of resistant Enterococcus faecium exposed to linezolid in an in vitro dynamic model.

Alieva KN, Golikova MV, Portnoy YA, Dovzhenko SA, Kobrin MB, Zinner SH, Firsov AA.

J Chemother. 2018 Oct - Dec;30(6-8):364-370. doi: 10.1080/1120009X.2018.1533267.

PMID:
30663551
7.

Predicting antibiotic combination effects on the selection of resistant Staphylococcus aureus: In vitro model studies with linezolid and gentamicin.

Zinner SH, Golikova MV, Strukova EN, Portnoy YA, Firsov AA.

Int J Antimicrob Agents. 2018 Dec;52(6):854-860. doi: 10.1016/j.ijantimicag.2018.09.005. Epub 2018 Sep 17.

PMID:
30236953
8.

Time inside the mutant selection window as a predictor of staphylococcal resistance to linezolid.

Alieva KN, Strukova EN, Golikova MV, Portnoy YA, Zinner SH, Firsov AA.

J Antibiot (Tokyo). 2018 May;71(5):514-521. doi: 10.1038/s41429-017-0016-9. Epub 2018 Jan 18.

PMID:
29348530
9.

Testing the mutant selection window hypothesis with Staphylococcus aureus exposed to linezolid in an in vitro dynamic model.

Firsov AA, Alieva KN, Strukova EN, Golikova MV, Portnoy YA, Dovzhenko SA, Kobrin MB, Romanov AV, Edelstein MV, Zinner SH.

J Antimicrob Chemother. 2017 Nov 1;72(11):3100-3107. doi: 10.1093/jac/dkx249.

PMID:
28981793
10.

Species differences in ciprofloxacin resistance among Gram-negative bacteria: can "anti-mutant" ratios of the area under the concentration-time curve to the MIC be achieved clinically?

Strukova EN, Portnoy YA, Zinner SH, Firsov AA.

J Chemother. 2017 Dec;29(6):351-357. doi: 10.1080/1120009X.2017.1335980. Epub 2017 Jun 6.

PMID:
28587559
11.

Burden of antimicrobial resistance in an era of decreasing susceptibility.

Tillotson GS, Zinner SH.

Expert Rev Anti Infect Ther. 2017 Jul;15(7):663-676. doi: 10.1080/14787210.2017.1337508. Epub 2017 Jun 13.

PMID:
28580804
12.

Investigation of previously implicated genetic variants in chronic tic disorders: a transmission disequilibrium test approach.

Abdulkadir M, Londono D, Gordon D, Fernandez TV, Brown LW, Cheon KA, Coffey BJ, Elzerman L, Fremer C, Fründt O, Garcia-Delgar B, Gilbert DL, Grice DE, Hedderly T, Heyman I, Hong HJ, Huyser C, Ibanez-Gomez L, Jakubovski E, Kim YK, Kim YS, Koh YJ, Kook S, Kuperman S, Leventhal B, Ludolph AG, Madruga-Garrido M, Maras A, Mir P, Morer A, Müller-Vahl K, Münchau A, Murphy TL, Plessen KJ, Roessner V, Shin EY, Song DH, Song J, Tübing J, van den Ban E, Visscher F, Wanderer S, Woods M, Zinner SH, King RA, Tischfield JA, Heiman GA, Hoekstra PJ, Dietrich A.

Eur Arch Psychiatry Clin Neurosci. 2018 Apr;268(3):301-316. doi: 10.1007/s00406-017-0808-8. Epub 2017 May 29.

13.

Predicting effects of antibiotic combinations using MICs determined at pharmacokinetically derived concentration ratios: in vitro model studies with linezolid- and rifampicin-exposed Staphylococcus aureus.

Golikova MV, Strukova EN, Portnoy YA, Dovzhenko SA, Kobrin MB, Zinner SH, Firsov AA.

J Chemother. 2017 Oct;29(5):267-273. doi: 10.1080/1120009X.2017.1281093. Epub 2017 Feb 13.

PMID:
28192070
14.

Pharmacokinetically-based prediction of the effects of antibiotic combinations on resistant Staphylococcus aureus mutants: in vitro model studies with linezolid and rifampicin.

Firsov AA, Golikova MV, Strukova EN, Portnoy YA, Dovzhenko SA, Kobrin MB, Zinner SH.

J Chemother. 2017 Aug;29(4):220-226. doi: 10.1080/1120009X.2016.1245174. Epub 2016 Oct 17.

PMID:
27748167
15.

Pre- and perinatal complications in relation to Tourette syndrome and co-occurring obsessive-compulsive disorder and attention-deficit/hyperactivity disorder.

Abdulkadir M, Tischfield JA, King RA, Fernandez TV, Brown LW, Cheon KA, Coffey BJ, de Bruijn SF, Elzerman L, Garcia-Delgar B, Gilbert DL, Grice DE, Hagstrøm J, Hedderly T, Heyman I, Hong HJ, Huyser C, Ibanez-Gomez L, Kim YK, Kim YS, Koh YJ, Kook S, Kuperman S, Lamerz A, Leventhal B, Ludolph AG, Madruga-Garrido M, Maras A, Messchendorp MD, Mir P, Morer A, Münchau A, Murphy TL, Openneer TJ, Plessen KJ, Rath JJ, Roessner V, Fründt O, Shin EY, Sival DA, Song DH, Song J, Stolte AM, Tübing J, van den Ban E, Visscher F, Wanderer S, Woods M, Zinner SH, State MW, Heiman GA, Hoekstra PJ, Dietrich A.

J Psychiatr Res. 2016 Nov;82:126-35. doi: 10.1016/j.jpsychires.2016.07.017. Epub 2016 Jul 22.

16.

The emerging problem of bacterial resistance in cancer patients; proceedings of a workshop held by MASCC "Neutropenia, Infection and Myelosuppression" Study Group during the MASCC annual meeting held in Berlin on 27-29 June 2013.

Rapoport B, Klastersky J, Raftopoulos H, Freifeld A, Aoun M, Zinner SH, Rolston KV.

Support Care Cancer. 2016 Jul;24(7):2819-26. doi: 10.1007/s00520-016-3183-5. Epub 2016 Apr 20. No abstract available.

PMID:
27098065
17.

Searching for the Optimal Predictor of Ciprofloxacin Resistance in Klebsiella pneumoniae by Using In Vitro Dynamic Models.

Strukova EN, Portnoy YA, Romanov AV, Edelstein MV, Zinner SH, Firsov AA.

Antimicrob Agents Chemother. 2015 Dec 7;60(3):1208-15. doi: 10.1128/AAC.02334-15.

18.

Predictors of bacterial resistance using in vitro dynamic models: area under the concentration-time curve related to either the minimum inhibitory or mutant prevention antibiotic concentration.

Strukova EN, Portnoy YA, Zinner SH, Firsov AA.

J Antimicrob Chemother. 2016 Mar;71(3):678-84. doi: 10.1093/jac/dkv387. Epub 2015 Nov 30.

PMID:
26626718
19.

Dental Homes for Children With Autism: A Longitudinal Analysis of Iowa Medicaid's I-Smile Program.

Chi DL, Momany ET, Mancl LA, Lindgren SD, Zinner SH, Steinman KJ.

Am J Prev Med. 2016 May;50(5):609-615. doi: 10.1016/j.amepre.2015.08.022. Epub 2015 Oct 26.

20.

Bacterial antibiotic resistance studies using in vitro dynamic models: Population analysis vs. susceptibility testing as endpoints of mutant enrichment.

Firsov AA, Strukova EN, Portnoy YA, Shlykova DS, Zinner SH.

Int J Antimicrob Agents. 2015 Sep;46(3):313-8. doi: 10.1016/j.ijantimicag.2015.06.007. Epub 2015 Jul 16.

PMID:
26297633
21.

Antibiotic Development and the Evolving Role of Pharmacodynamics - As Good as It Gets?

Tillotson GS, Zinner SH.

EBioMedicine. 2015 Jun 12;2(7):615-6. doi: 10.1016/j.ebiom.2015.06.010. eCollection 2015 Jul. No abstract available.

22.

Pilot Testing Behavior Therapy for Chronic Tic Disorders in Neurology and Developmental Pediatrics Clinics.

Ricketts EJ, Gilbert DL, Zinner SH, Mink JW, Lipps TD, Wiegand GA, Vierhile AE, Ely LJ, Piacentini J, Walkup JT, Woods DW.

J Child Neurol. 2016 Mar;31(4):444-50. doi: 10.1177/0883073815599257. Epub 2015 Aug 13.

PMID:
26271790
23.

In vitro resistance studies with bacteria that exhibit low mutation frequencies: prediction of "antimutant" linezolid concentrations using a mixed inoculum containing both susceptible and resistant Staphylococcus aureus.

Firsov AA, Golikova MV, Strukova EN, Portnoy YA, Romanov AV, Edelstein MV, Zinner SH.

Antimicrob Agents Chemother. 2015 Feb;59(2):1014-9. doi: 10.1128/AAC.04214-14. Epub 2014 Dec 1.

24.

Predicting bacterial resistance using the time inside the mutant selection window: possibilities and limitations.

Firsov AA, Portnoy YA, Strukova EN, Shlykova DS, Zinner SH.

Int J Antimicrob Agents. 2014 Oct;44(4):301-5. doi: 10.1016/j.ijantimicag.2014.06.013. Epub 2014 Jul 27.

PMID:
25218155
25.

A national profile of Tourette syndrome, 2011-2012.

Bitsko RH, Holbrook JR, Visser SN, Mink JW, Zinner SH, Ghandour RM, Blumberg SJ.

J Dev Behav Pediatr. 2014 Jun;35(5):317-22. doi: 10.1097/DBP.0000000000000065.

26.

Bacterial resistance studies using in vitro dynamic models: the predictive power of the mutant prevention and minimum inhibitory antibiotic concentrations.

Firsov AA, Strukova EN, Shlykova DS, Portnoy YA, Kozyreva VK, Edelstein MV, Dovzhenko SA, Kobrin MB, Zinner SH.

Antimicrob Agents Chemother. 2013 Oct;57(10):4956-62. doi: 10.1128/AAC.00578-13. Epub 2013 Jul 29.

27.

Paul Ehrlich, a prescient pioneer in the field of antimicrobial chemotherapy: what did he foresee a century ago?

Tillotson GS, Zinner SH.

Expert Rev Anti Infect Ther. 2013 Feb;11(2):113-5. doi: 10.1586/eri.12.166. No abstract available.

PMID:
23409816
28.

Concentration-resistance relationships with Pseudomonas aeruginosa exposed to doripenem and ciprofloxacin in an in vitro model.

Zinner SH, Gilbert D, Greer K, Portnoy YA, Firsov AA.

J Antimicrob Chemother. 2013 Apr;68(4):881-7. doi: 10.1093/jac/dks463. Epub 2012 Nov 21.

PMID:
23175594
29.

Psychoeducational characteristics of children with hypohidrotic ectodermal dysplasia.

Maxim RA, Zinner SH, Matsuo H, Prosser TM, Fete M, Leet TL, Fete TJ.

ScientificWorldJournal. 2012;2012:532371. doi: 10.1100/2012/532371. Epub 2012 Mar 12.

30.

Comparative pharmacodynamics and antimutant potentials of doripenem and imipenem with ciprofloxacin-resistant Pseudomonas aeruginosa in an in vitro model.

Firsov AA, Gilbert D, Greer K, Portnoy YA, Zinner SH.

Antimicrob Agents Chemother. 2012 Mar;56(3):1223-8. doi: 10.1128/AAC.05964-11. Epub 2011 Dec 27.

31.

The impact of Tourette Syndrome in adults: results from the Tourette Syndrome impact survey.

Conelea CA, Woods DW, Zinner SH, Budman CL, Murphy TK, Scahill LD, Compton SN, Walkup JT.

Community Ment Health J. 2013 Feb;49(1):110-20. doi: 10.1007/s10597-011-9465-y. Epub 2011 Nov 4.

PMID:
22052430
32.

Peer victimization in youth with Tourette syndrome and other chronic tic disorders.

Zinner SH, Conelea CA, Glew GM, Woods DW, Budman CL.

Child Psychiatry Hum Dev. 2012 Feb;43(1):124-36. doi: 10.1007/s10578-011-0249-y.

PMID:
21879319
33.

A phenomenological investigation of women with Tourette or other chronic tic disorders.

Lewin AB, Murphy TK, Storch EA, Conelea CA, Woods DW, Scahill LD, Compton SN, Zinner SH, Budman CL, Walkup JT.

Compr Psychiatry. 2012 Jul;53(5):525-34. doi: 10.1016/j.comppsych.2011.07.004. Epub 2011 Aug 24.

PMID:
21867997
34.

The antistaphylococcal pharmacodynamics of linezolid alone and in combination with doxycycline in an in vitro dynamic model.

Smirnova MV, Strukova EN, Portnoy YA, Dovzhenko SA, Kobrin MB, Zinner SH, Firsov AA.

J Chemother. 2011 Jun;23(3):140-4.

PMID:
21742582
35.

Exploring the impact of chronic tic disorders on youth: results from the Tourette Syndrome Impact Survey.

Conelea CA, Woods DW, Zinner SH, Budman C, Murphy T, Scahill LD, Compton SN, Walkup J.

Child Psychiatry Hum Dev. 2011 Apr;42(2):219-42. doi: 10.1007/s10578-010-0211-4.

PMID:
21046225
36.

The roles of anxiety and depression in connecting tic severity and functional impairment.

Lewin AB, Storch EA, Conelea CA, Woods DW, Zinner SH, Budman CL, Scahill LD, Compton SN, Walkup JT, Murphy TK.

J Anxiety Disord. 2011 Mar;25(2):164-8. doi: 10.1016/j.janxdis.2010.08.016.

PMID:
20889290
37.

Movement disorders ii: chorea, dystonia, myoclonus, and tremor.

Mink JW, Zinner SH.

Pediatr Rev. 2010 Jul;31(7):287-94; quiz 295. doi: 10.1542/pir.31-7-287. No abstract available.

PMID:
20595442
38.

Movement disorders I: tics and stereotypies.

Zinner SH, Mink JW.

Pediatr Rev. 2010 Jun;31(6):223-33. doi: 10.1542/pir.31-6-223. Review. No abstract available.

PMID:
20516234
39.

Developmental and behavioral disorders grown up: Tourette's disorder.

Zinner SH, Coffey BJ.

J Dev Behav Pediatr. 2009 Dec;30(6):560-73. doi: 10.1097/DBP.0b013e3181bd7f3e. Review. No abstract available.

PMID:
19996902
40.

The impact of duration of antibiotic exposure on bacterial resistance predictions using in vitro dynamic models.

Smirnova MV, Vostrov SN, Strukova EV, Dovzhenko SA, Kobrin MB, Portnoy YA, Zinner SH, Firsov AA.

J Antimicrob Chemother. 2009 Oct;64(4):815-20. doi: 10.1093/jac/dkp287. Epub 2009 Aug 11.

PMID:
19671586
41.

Coprophenomena in Tourette syndrome.

Freeman RD, Zinner SH, Müller-Vahl KR, Fast DK, Burd LJ, Kano Y, Rothenberger A, Roessner V, Kerbeshian J, Stern JS, Jankovic J, Loughin T, Janik P, Shady G, Robertson MM, Lang AE, Budman C, Magor A, Bruun R, Berlin CM Jr.

Dev Med Child Neurol. 2009 Mar;51(3):218-27. doi: 10.1111/j.1469-8749.2008.03135.x. Epub 2008 Dec 4.

42.

Linezolid pharmacodynamics with Staphylococcus aureus in an in vitro dynamic model.

Strukova EN, Smirnova MV, Vostrov SN, Lubenko IY, Firsov AA, Zinner SH, Portnoy YA.

Int J Antimicrob Agents. 2009 Mar;33(3):251-4. doi: 10.1016/j.ijantimicag.2008.09.006. Epub 2008 Dec 17.

PMID:
19095420
43.

Enrichment of resistant Staphylococcus aureus at ciprofloxacin concentrations simulated within the mutant selection window: bolus versus continuous infusion.

Firsov AA, Smirnova MV, Strukova EN, Vostrov SN, Portnoy YA, Zinner SH.

Int J Antimicrob Agents. 2008 Dec;32(6):488-93. doi: 10.1016/j.ijantimicag.2008.06.031. Epub 2008 Sep 14.

PMID:
18790614
44.

Telavancin and vancomycin pharmacodynamics with Staphylococcus aureus in an in vitro dynamic model.

Lubenko IY, Strukova EV, Smirnova MV, Vostrov SN, Portnoy YA, Zinner SH, Firsov AA.

J Antimicrob Chemother. 2008 Nov;62(5):1065-9. doi: 10.1093/jac/dkn288. Epub 2008 Jul 17.

PMID:
18635520
45.

Enrichment of fluoroquinolone-resistant Staphylococcus aureus: oscillating ciprofloxacin concentrations simulated at the upper and lower portions of the mutant selection window.

Firsov AA, Lubenko IY, Smirnova MV, Strukova EN, Zinner SH.

Antimicrob Agents Chemother. 2008 Jun;52(6):1924-8. doi: 10.1128/AAC.01371-07. Epub 2008 Mar 31.

46.

Selection of linezolid-resistant Enterococcus faecium in an in vitro dynamic model: protective effect of doxycycline.

Zinner SH, Gilbert D, Lubenko IY, Greer K, Firsov AA.

J Antimicrob Chemother. 2008 Mar;61(3):629-35. doi: 10.1093/jac/dkm542. Epub 2008 Feb 1.

PMID:
18245198
47.

Antibiotic use: present and future.

Zinner SH.

New Microbiol. 2007 Jul;30(3):321-5. Review.

48.

Antibiotic pharmacodynamics and bacterial resistance: usefulness of in vitro models.

Zinner SH, Firsov A.

Curr Infect Dis Rep. 2007 May;9(3):175-7. No abstract available.

PMID:
17430696
49.
50.

Testing the mutant selection window hypothesis with Staphylococcus aureus exposed to daptomycin and vancomycin in an in vitro dynamic model.

Firsov AA, Smirnova MV, Lubenko IY, Vostrov SN, Portnoy YA, Zinner SH.

J Antimicrob Chemother. 2006 Dec;58(6):1185-92. Epub 2006 Oct 5.

PMID:
17028094

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