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Items: 24

1.

SMAD signaling promotes melanoma metastasis independently of phenotype switching.

Tuncer E, Calçada RR, Zingg D, Varum S, Cheng P, Freiberger SN, Deng CX, Kleiter I, Levesque MP, Dummer R, Sommer L.

J Clin Invest. 2019 Apr 30;130. pii: 94295. doi: 10.1172/JCI94295.

2.

Yin Yang 1 Orchestrates a Metabolic Program Required for Both Neural Crest Development and Melanoma Formation.

Varum S, Baggiolini A, Zurkirchen L, Atak ZK, Cantù C, Marzorati E, Bossart R, Wouters J, Häusel J, Tuncer E, Zingg D, Veen D, John N, Balz M, Levesque MP, Basler K, Aerts S, Zamboni N, Dummer R, Sommer L.

Cell Stem Cell. 2019 Apr 4;24(4):637-653.e9. doi: 10.1016/j.stem.2019.03.011.

PMID:
30951662
3.

EZH2-Mediated Primary Cilium Deconstruction Drives Metastatic Melanoma Formation.

Zingg D, Debbache J, Peña-Hernández R, Antunes AT, Schaefer SM, Cheng PF, Zimmerli D, Haeusel J, Calçada RR, Tuncer E, Zhang Y, Bossart R, Wong KK, Basler K, Dummer R, Santoro R, Levesque MP, Sommer L.

Cancer Cell. 2018 Jul 9;34(1):69-84.e14. doi: 10.1016/j.ccell.2018.06.001. Epub 2018 Jun 28.

PMID:
30008323
4.

Rare, yet relevant tumor cells - A new twist to melanoma cell plasticity.

Zingg D, Sommer L.

Pigment Cell Melanoma Res. 2018 Jan;31(1):7-9. doi: 10.1111/pcmr.12643. Epub 2017 Oct 3. No abstract available.

PMID:
28898550
5.

The Histone Methyltransferase Ezh2 Controls Mechanisms of Adaptive Resistance to Tumor Immunotherapy.

Zingg D, Arenas-Ramirez N, Sahin D, Rosalia RA, Antunes AT, Haeusel J, Sommer L, Boyman O.

Cell Rep. 2017 Jul 25;20(4):854-867. doi: 10.1016/j.celrep.2017.07.007.

6.

Social and economic burden of recurrent urinary tract infections and quality of life: a patient web-based study (GESPRIT).

Wagenlehner F, Wullt B, Ballarini S, Zingg D, Naber KG.

Expert Rev Pharmacoecon Outcomes Res. 2018 Feb;18(1):107-117. doi: 10.1080/14737167.2017.1359543. Epub 2017 Jul 31.

PMID:
28737469
7.

Epidemiological and Economic Evaluation of Alternative On-Farm Management Scenarios for Ovine Footrot in Switzerland.

Zingg D, Steinbach S, Kuhlgatz C, Rediger M, Schüpbach-Regula G, Aepli M, Grøneng GM, Dürr S.

Front Vet Sci. 2017 May 16;4:70. doi: 10.3389/fvets.2017.00070. eCollection 2017.

8.

Improved cancer immunotherapy by a CD25-mimobody conferring selectivity to human interleukin-2.

Arenas-Ramirez N, Zou C, Popp S, Zingg D, Brannetti B, Wirth E, Calzascia T, Kovarik J, Sommer L, Zenke G, Woytschak J, Regnier CH, Katopodis A, Boyman O.

Sci Transl Med. 2016 Nov 30;8(367):367ra166.

PMID:
27903862
9.

Evidence for Emergency Vaccination Having Played a Crucial Role to Control the 1965/66 Foot-and-Mouth Disease Outbreak in Switzerland.

Zingg D, Häsler S, Schuepbach-Regula G, Schwermer H, Dürr S.

Front Vet Sci. 2015 Dec 14;2:72. doi: 10.3389/fvets.2015.00072. eCollection 2015.

10.

Methylation-dependent SOX9 expression mediates invasion in human melanoma cells and is a negative prognostic factor in advanced melanoma.

Cheng PF, Shakhova O, Widmer DS, Eichhoff OM, Zingg D, Frommel SC, Belloni B, Raaijmakers MI, Goldinger SM, Santoro R, Hemmi S, Sommer L, Dummer R, Levesque MP.

Genome Biol. 2015 Feb 22;16:42. doi: 10.1186/s13059-015-0594-4.

11.

Antagonistic cross-regulation between Sox9 and Sox10 controls an anti-tumorigenic program in melanoma.

Shakhova O, Cheng P, Mishra PJ, Zingg D, Schaefer SM, Debbache J, Häusel J, Matter C, Guo T, Davis S, Meltzer P, Mihic-Probst D, Moch H, Wegner M, Merlino G, Levesque MP, Dummer R, Santoro R, Cinelli P, Sommer L.

PLoS Genet. 2015 Jan 28;11(1):e1004877. doi: 10.1371/journal.pgen.1004877. eCollection 2015 Jan.

12.

The epigenetic modifier EZH2 controls melanoma growth and metastasis through silencing of distinct tumour suppressors.

Zingg D, Debbache J, Schaefer SM, Tuncer E, Frommel SC, Cheng P, Arenas-Ramirez N, Haeusel J, Zhang Y, Bonalli M, McCabe MT, Creasy CL, Levesque MP, Boyman O, Santoro R, Shakhova O, Dummer R, Sommer L.

Nat Commun. 2015 Jan 22;6:6051. doi: 10.1038/ncomms7051.

PMID:
25609585
13.

Tenascin-C is required for normal Wnt/β-catenin signaling in the whisker follicle stem cell niche.

Hendaoui I, Tucker RP, Zingg D, Bichet S, Schittny J, Chiquet-Ehrismann R.

Matrix Biol. 2014 Nov;40:46-53. doi: 10.1016/j.matbio.2014.08.017. Epub 2014 Sep 6.

14.

TGF-β-induced differentiation into myofibroblasts involves specific regulation of two MKL1 isoforms.

Scharenberg MA, Pippenger BE, Sack R, Zingg D, Ferralli J, Schenk S, Martin I, Chiquet-Ehrismann R.

J Cell Sci. 2014 Mar 1;127(Pt 5):1079-91. doi: 10.1242/jcs.142075. Epub 2014 Jan 14.

15.

Sox10 promotes the formation and maintenance of giant congenital naevi and melanoma.

Shakhova O, Zingg D, Schaefer SM, Hari L, Civenni G, Blunschi J, Claudinot S, Okoniewski M, Beermann F, Mihic-Probst D, Moch H, Wegner M, Dummer R, Barrandon Y, Cinelli P, Sommer L.

Nat Cell Biol. 2012 Aug;14(8):882-90. doi: 10.1038/ncb2535. Epub 2012 Jul 8.

PMID:
22772081
16.

Sulfate-driven elemental sparing is regulated at the transcriptional and posttranscriptional levels in a filamentous cyanobacterium.

Gutu A, Alvey RM, Bashour S, Zingg D, Kehoe DM.

J Bacteriol. 2011 Mar;193(6):1449-60. doi: 10.1128/JB.00885-10. Epub 2011 Jan 14.

17.

Responsiveness of fibrocytes to toll-like receptor danger signals.

Balmelli C, Alves MP, Steiner E, Zingg D, Peduto N, Ruggli N, Gerber H, McCullough K, Summerfield A.

Immunobiology. 2007;212(9-10):693-9. Epub 2007 Nov 13.

PMID:
18086371
18.

Differential activation of the phosphatidylinositol 3'-kinase/Akt survival pathway by ionizing radiation in tumor and primary endothelial cells.

Zingg D, Riesterer O, Fabbro D, Glanzmann C, Bodis S, Pruschy M.

Cancer Res. 2004 Aug 1;64(15):5398-406.

19.

Abstracts from the 8th Annual Meeting of the Scientific Association of Swiss Radiation Oncology (SASRO).

Allal AS, Ares C, Dulguerov P, Tschanz E, Verdan C, Mhawech P, Riesterer O, Honer M, Vuong V, Jochum W, Zingg D, Bodis S, Ametamey S, Pruschy M, Inteeworn N, Ohlerth S, Höpfl G, Roos M, Wergin M, Rohrer Bley C, Gassmann M, Kaser-Hotz B, Berthou S, Aebersold DM, Ganapathipillai S, Streit B, Stalder D, Gruber G, Greiner RH, Zimmer Y, Lutters G, Krek W, Tenzer A, Hofstetter B, Bonny C, Azria A, Larbouret C, Cunat S, Ozsahin M, Zouhair A, Gourgou S, Martineau P, Evans DB, Romieu G, Pujol P, Pèlegrin A, Heuberger J, Kestenholz P, Taverna Ch, Lardinois D, Jörger M, Schneiter D, Jerman M, Weder W, Stahel R, Bodis S, Vees H, Mach N, Hügli A, Balmer Majno S, Beer KT, Friedrich EE, Ciernik IF, Stanek N, Taverna C, Greiner R, Mahler F, Landmann Ch, Studer G, Bernier J, Gallino A, Juelke PD, Hafner HP, Jamshidi P, Erne P, Resink TJ, Thum P, Notter M, Bargetzi M, Suleiman M, Luthi JC, Bieri S, Curschmann J, Pajic B, Kranzbühler H, Lippold B, Ueltschi G, Bonetti M, Nasi ML, Price KN, Castiglione-Gertsch M, Rudenstam CM, Holmberg SB, Lindtner J, Gol-Ouh R, Collins J, Crivellari D, Carbone A, Thürlimann B, Simoncini E, Fey MF, Gelber RD, Coates AS, Goldhirsch A, Jeanneret Sozzi W, Kramar A, Mirimanoff RO, Azria D, Taussky D, Becker M, Kranzbuehler H, Weitzel M, Bortoluzzi L, Behrensmeier F, Isaak B, Pasche P, Luthi F, Weber DC, Lomax AJ, Rutz HP, Pedroni ES, Verwey J, Goitein G, Timmermann B, Lomax A, Bolsi A, Weber D, Bentzen SM, Khalil AA, Saunders MI, Horiot JC, Van den Bogaert W, Cummings BJ, Dische S, Slosman DO, Kebdani T, Allaoua M, Stadelmann O, Stupp R, Pica A, Dubois JB, Oehler C, Ulmer U, Lütolf UM, Huser M, Burger C, Szekely G, Davis JB, Gervaz P, Gertsch P, Morel P, Roth AD, Zenklusen H, Schott A, Curti G, Schefer H, Kolotas C, Thalmann G, Vetterli D, Kemmerling L, Mini R, Rouzaud M, Nouet P, Mollà M, Escudé L, Miralbell R, Beer K, von Briel C, Jichlinski P, Guillou L, Fogliata A, Nicolini G, Cozzi L, Hafner HP, Hueber P, Szczerba D, Born EJ, Dipasquale G, Jargy C, Munier F, Balmer A, Do HP, Pasche G, Wang H, Moeckli R, Boehringer T, Coray A, Lin S, Pedroni E, Rutz H, Baumert BG, Norton IA, Schoenmaker E, Krayenbühl J, Bründler MA, Allemann K, Laluhovà D, Collen T, Coucke P, Ries G, Rufibach K, Huguenin P, Abdou M, Girardet C, Vees HJ, Bigler R, Özsoy O, Bouville S, Corminboeuf F, Betz M, Matzinger O, Tebeu P, Popowski Y, Verkooijen H, Bouchardy C, Ludicke F, Usel M, Major A, Merçay A, Pache G, Bulling S, Bressan S, Valley JF, Motta M, Presilla S, Richetti A, Franzetti A, Pesce G.

Strahlenther Onkol. 2004 Jun;180 Suppl 1:89-108. doi: 10.1007/BF03356735. No abstract available.

PMID:
27137923
20.

Degradation of PKB/Akt protein by inhibition of the VEGF receptor/mTOR pathway in endothelial cells.

Riesterer O, Zingg D, Hummerjohann J, Bodis S, Pruschy M.

Oncogene. 2004 Jun 3;23(26):4624-35.

PMID:
15064712
21.

Novel radiosensitizers for locally advanced epithelial tumors: inhibition of the PI3K/Akt survival pathway in tumor cells and in tumor-associated endothelial cells as a novel treatment strategy?

Riesterer O, Tenzer A, Zingg D, Hofstetter B, Vuong V, Pruschy M, Bodis S.

Int J Radiat Oncol Biol Phys. 2004 Feb 1;58(2):361-8.

PMID:
14751504
22.

Signal transduction inhibitors as radiosensitizers.

Tenzer A, Zingg D, Riesterer O, Vuong V, Bodis S, Pruschy M.

Curr Med Chem Anticancer Agents. 2002 Nov;2(6):727-42. Review.

PMID:
12678723
23.

The phosphatidylinositide 3'-kinase/Akt survival pathway is a target for the anticancer and radiosensitizing agent PKC412, an inhibitor of protein kinase C.

Tenzer A, Zingg D, Rocha S, Hemmings B, Fabbro D, Glanzmann C, Schubiger PA, Bodis S, Pruschy M.

Cancer Res. 2001 Nov 15;61(22):8203-10.

24.

One of two hemN genes in Bradyrhizobium japonicum is functional during anaerobic growth and in symbiosis.

Fischer HM, Velasco L, Delgado MJ, Bedmar EJ, Schären S, Zingg D, Göttfert M, Hennecke H.

J Bacteriol. 2001 Feb;183(4):1300-11.

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