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Items: 1 to 50 of 102

1.

DLC1 suppresses NF-κB activity in prostate cancer cells due to its stabilizing effect on adherens junctions.

Tripathi V, Popescu NC, Zimonjic DB.

Springerplus. 2014 Jan 14;3:27. doi: 10.1186/2193-1801-3-27. eCollection 2014.

2.

In vitro and in vivo effects of geranylgeranyltransferase I inhibitor P61A6 on non-small cell lung cancer cells.

Zimonjic DB, Chan LN, Tripathi V, Lu J, Kwon O, Popescu NC, Lowy DR, Tamanoi F.

BMC Cancer. 2013 Apr 22;13:198. doi: 10.1186/1471-2407-13-198.

3.

DLC1 induces expression of E-cadherin in prostate cancer cells through Rho pathway and suppresses invasion.

Tripathi V, Popescu NC, Zimonjic DB.

Oncogene. 2014 Feb 6;33(6):724-33. doi: 10.1038/onc.2013.7. Epub 2013 Feb 4.

PMID:
23376848
4.
5.

DLC1 interaction with α-catenin stabilizes adherens junctions and enhances DLC1 antioncogenic activity.

Tripathi V, Popescu NC, Zimonjic DB.

Mol Cell Biol. 2012 Jun;32(11):2145-59. doi: 10.1128/MCB.06580-11. Epub 2012 Apr 2.

6.

DLC1 interaction with S100A10 mediates inhibition of in vitro cell invasion and tumorigenicity of lung cancer cells through a RhoGAP-independent mechanism.

Yang X, Popescu NC, Zimonjic DB.

Cancer Res. 2011 Apr 15;71(8):2916-25. doi: 10.1158/0008-5472.CAN-10-2158. Epub 2011 Mar 3.

7.

Effect of KEPI (Ppp1r14c) deletion on morphine analgesia and tolerance in mice of different genetic backgrounds: when a knockout is near a relevant quantitative trait locus.

Drgonova J, Zimonjic DB, Hall FS, Uhl GR.

Neuroscience. 2010 Feb 3;165(3):882-95. doi: 10.1016/j.neuroscience.2009.10.007. Epub 2009 Oct 9.

8.

Role of SV40 integration site at chromosomal interval 1q21.1 in immortalized CRL2504 cells.

Liu J, Kaur G, Zhawar VK, Zimonjic DB, Popescu NC, Kandpal RP, Athwal RS.

Cancer Res. 2009 Oct 1;69(19):7819-25. doi: 10.1158/0008-5472.CAN-09-1003. Epub 2009 Sep 29.

9.

Acquired genetic and functional alterations associated with transforming growth factor beta type I resistance in Hep3B human hepatocellular carcinoma cell line.

Zimonjic DB, Zhou X, Lee JS, Ullmannova-Benson V, Tripathi V, Thorgeirsson SS, Popescu NC.

J Cell Mol Med. 2009 Sep;13(9B):3985-92. doi: 10.1111/j.1582-4934.2009.00769.x. Epub 2009 May 1.

10.

Recurrent and nonrandom DNA copy number and chromosome alterations in Myc transgenic mouse model for hepatocellular carcinogenesis: implications for human disease.

Zimonjic DB, Ullmannova-Benson V, Factor VM, Thorgeirsson SS, Popescu NC.

Cancer Genet Cytogenet. 2009 May;191(1):17-26. doi: 10.1016/j.cancergencyto.2008.12.014.

11.

DLC1 tumor suppressor gene inhibits migration and invasion of multiple myeloma cells through RhoA GTPase pathway.

Ullmannova-Benson V, Guan M, Zhou X, Tripathi V, Yang XY, Zimonjic DB, Popescu NC.

Leukemia. 2009 Feb;23(2):383-90. doi: 10.1038/leu.2008.285. Epub 2008 Oct 16.

13.

Delayed kinetics of DNA double-strand break processing in normal and pathological aging.

Sedelnikova OA, Horikawa I, Redon C, Nakamura A, Zimonjic DB, Popescu NC, Bonner WM.

Aging Cell. 2008 Jan;7(1):89-100. Epub 2007 Dec 19.

14.

DLC-1:a Rho GTPase-activating protein and tumour suppressor.

Durkin ME, Yuan BZ, Zhou X, Zimonjic DB, Lowy DR, Thorgeirsson SS, Popescu NC.

J Cell Mol Med. 2007 Sep-Oct;11(5):1185-207. Review.

15.

Nonclassic functions of human topoisomerase I: genome-wide and pharmacologic analyses.

Miao ZH, Player A, Shankavaram U, Wang YH, Zimonjic DB, Lorenzi PL, Liao ZY, Liu H, Shimura T, Zhang HL, Meng LH, Zhang YW, Kawasaki ES, Popescu NC, Aladjem MI, Goldstein DJ, Weinstein JN, Pommier Y.

Cancer Res. 2007 Sep 15;67(18):8752-61.

16.

Enrichment of a population of mammary gland cells that form mammospheres and have in vivo repopulating activity.

Liao MJ, Zhang CC, Zhou B, Zimonjic DB, Mani SA, Kaba M, Gifford A, Reinhardt F, Popescu NC, Guo W, Eaton EN, Lodish HF, Weinberg RA.

Cancer Res. 2007 Sep 1;67(17):8131-8.

17.

Selective suppression of lymphomas by functional loss of Hsf1 in a p53-deficient mouse model for spontaneous tumors.

Min JN, Huang L, Zimonjic DB, Moskophidis D, Mivechi NF.

Oncogene. 2007 Aug 2;26(35):5086-97. Epub 2007 Feb 19.

PMID:
17310987
18.

POTE paralogs are induced and differentially expressed in many cancers.

Bera TK, Saint Fleur A, Lee Y, Kydd A, Hahn Y, Popescu NC, Zimonjic DB, Lee B, Pastan I.

Cancer Res. 2006 Jan 1;66(1):52-6.

19.

Androgen inducibility of Fgf8 in Shionogi carcinoma 115 cells correlates with an adjacent t(5;19) translocation.

Erdreich-Epstein A, Ganguly AK, Shi XH, Zimonjic DB, Shackleford GM.

Genes Chromosomes Cancer. 2006 Feb;45(2):169-81.

PMID:
16252261
20.

Chromosomal aberrations in cell lines derived from thyroid tumors spontaneously developed in TRbetaPV/PV mice.

Zimonjic DB, Kato Y, Ying H, Popescu NC, Cheng SY.

Cancer Genet Cytogenet. 2005 Sep;161(2):104-9.

PMID:
16102579
21.

Assignment of murine placental cathepsin R to mouse chromosome bands 13B2-B3 by fluorescence in situ hybridization.

Zimonjic DB, Liu J, Xu WH, Zhou X, Popescu NC, Shi GP.

Cytogenet Genome Res. 2005;111(1):96. No abstract available.

PMID:
16097084
22.

The human AKNA gene expresses multiple transcripts and protein isoforms as a result of alternative promoter usage, splicing, and polyadenylation.

Sims-Mourtada JC, Bruce S, McKeller MR, Rangel R, Guzman-Rojas L, Cain K, Lopez C, Zimonjic DB, Popescu NC, Gordon J, Wilkinson MF, Martinez-Valdez H.

DNA Cell Biol. 2005 May;24(5):325-38.

PMID:
15869410
23.

Functional identification of a BAC clone from 16q24 carrying a senescence gene SEN16 for breast cancer cells.

Kaur GP, Reddy DE, Zimonjic DB, de Riel JK, Athwal RS.

Oncogene. 2005 Jan 6;24(1):47-54.

PMID:
15558027
24.

Frequent downregulation and loss of WWOX gene expression in human hepatocellular carcinoma.

Park SW, Ludes-Meyers J, Zimonjic DB, Durkin ME, Popescu NC, Aldaz CM.

Br J Cancer. 2004 Aug 16;91(4):753-9.

25.

Thirteen-exon-motif signature for vertebrate nuclear and mitochondrial type IB topoisomerases.

Zhang H, Meng LH, Zimonjic DB, Popescu NC, Pommier Y.

Nucleic Acids Res. 2004 Apr 19;32(7):2087-92. Print 2004.

26.

Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks.

Sedelnikova OA, Horikawa I, Zimonjic DB, Popescu NC, Bonner WM, Barrett JC.

Nat Cell Biol. 2004 Feb;6(2):168-70.

PMID:
14755273
27.

SMAD5 gene expression, rearrangements, copy number, and amplification at fragile site FRA5C in human hepatocellular carcinoma.

Zimonjic DB, Durkin ME, Keck-Waggoner CL, Park SW, Thorgeirsson SS, Popescu NC.

Neoplasia. 2003 Sep-Oct;5(5):390-6.

28.

Neutral ceramidase gene: role in regulating ceramide-induced apoptosis.

Choi MS, Anderson MA, Zhang Z, Zimonjic DB, Popescu N, Mukherjee AB.

Gene. 2003 Oct 2;315:113-22.

PMID:
14557071
29.

GCF2: expression and molecular analysis of repression.

Rikiyama T, Curtis J, Oikawa M, Zimonjic DB, Popescu N, Murphy BA, Wilson MA, Johnson AC.

Biochim Biophys Acta. 2003 Oct 1;1629(1-3):15-25.

PMID:
14522076
30.

High-penetrance mouse model of acute promyelocytic leukemia with very low levels of PML-RARalpha expression.

Westervelt P, Lane AA, Pollock JL, Oldfather K, Holt MS, Zimonjic DB, Popescu NC, DiPersio JF, Ley TJ.

Blood. 2003 Sep 1;102(5):1857-65. Epub 2003 May 15.

31.
32.

DLC-1 gene inhibits human breast cancer cell growth and in vivo tumorigenicity.

Yuan BZ, Zhou X, Durkin ME, Zimonjic DB, Gumundsdottir K, Eyfjord JE, Thorgeirsson SS, Popescu NC.

Oncogene. 2003 Jan 23;22(3):445-50.

PMID:
12545165
33.

POTE, a highly homologous gene family located on numerous chromosomes and expressed in prostate, ovary, testis, placenta, and prostate cancer.

Bera TK, Zimonjic DB, Popescu NC, Sathyanarayana BK, Kumar V, Lee B, Pastan I.

Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16975-80. Epub 2002 Dec 10. Erratum in: Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):1462.

34.

Cloning, expression, and chromosomal localization of the mouse gene (Scgb3a1, alias Ugrp2) that encodes a member of the novel uteroglobin-related protein gene family.

Niimi T, Copeland NG, Gilbert DJ, Jenkins NA, Srisodsai A, Zimonjic DB, Keck-Waggoner CL, Popescu NC, Kimura S.

Cytogenet Genome Res. 2002;97(1-2):120-7.

PMID:
12438750
35.
36.

Telomerase contributes to tumorigenesis by a telomere length-independent mechanism.

Stewart SA, Hahn WC, O'Connor BF, Banner EN, Lundberg AS, Modha P, Mizuno H, Brooks MW, Fleming M, Zimonjic DB, Popescu NC, Weinberg RA.

Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):12606-11. Epub 2002 Aug 22.

37.

Chromosome-mediated alterations of the MYC gene in human cancer.

Popescu NC, Zimonjic DB.

J Cell Mol Med. 2002 Apr-Jun;6(2):151-9. Review.

38.

The fragile histidine triad/common chromosome fragile site 3B locus and repair-deficient cancers.

Turner BC, Ottey M, Zimonjic DB, Potoczek M, Hauck WW, Pequignot E, Keck-Waggoner CL, Sevignani C, Aldaz CM, McCue PA, Palazzo J, Huebner K, Popescu NC.

Cancer Res. 2002 Jul 15;62(14):4054-60.

39.

Characterization of a familial RCC-associated t(2;3)(q33;q21) chromosome translocation.

Podolski J, Byrski T, Zajaczek S, Druck T, Zimonjic DB, Popescu NC, Kata G, Borowka A, Gronwald J, Lubinski J, Huebner K.

J Hum Genet. 2001;46(12):685-93.

PMID:
11776380
40.

Novel genomic imbalances and chromosome translocations involving c-myc gene in Burkitt's lymphoma.

Zimonjic DB, Keck-Waggoner C, Popescu NC.

Leukemia. 2001 Oct;15(10):1582-8.

PMID:
11587216
41.
42.

Human mitochondrial topoisomerase I.

Zhang H, Barceló JM, Lee B, Kohlhagen G, Zimonjic DB, Popescu NC, Pommier Y.

Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10608-13. Epub 2001 Aug 28.

43.

Antiproliferative activity of ecteinascidin 743 is dependent upon transcription-coupled nucleotide-excision repair.

Takebayashi Y, Pourquier P, Zimonjic DB, Nakayama K, Emmert S, Ueda T, Urasaki Y, Kanzaki A, Akiyama SI, Popescu N, Kraemer KH, Pommier Y.

Nat Med. 2001 Aug;7(8):961-6. Erratum in: Nat Med 2001 Nov;7(11):1255.

PMID:
11479630
44.

DNA amplification associated with double minutes originating from chromosome 19 in mouse hepatocellular carcinoma.

Zimonjic DB, Zhang H, Shan Z, Factor V, Trent J, Thorgeirsson SS, Popescu NC.

Cytogenet Cell Genet. 2001;93(1-2):114-6.

PMID:
11474192
45.

Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells.

Elenbaas B, Spirio L, Koerner F, Fleming MD, Zimonjic DB, Donaher JL, Popescu NC, Hahn WC, Weinberg RA.

Genes Dev. 2001 Jan 1;15(1):50-65.

46.

Acquired, nonrandom chromosomal abnormalities associated with the development of acute promyelocytic leukemia in transgenic mice.

Zimonjic DB, Pollock JL, Westervelt P, Popescu NC, Ley TJ.

Proc Natl Acad Sci U S A. 2000 Nov 21;97(24):13306-11.

47.

Assignment of the MDM2 binding protein gene (MTBP) to human chromosome band 8q24 by in situ hybridization.

Boyd MT, Zimonjic DB, Popescu NC, Athwal R, Haines DS.

Cytogenet Cell Genet. 2000;90(1-2):64-5. No abstract available.

PMID:
11060448
48.

Genomic structure and chromosome location of the mouse RelA p65 gene (Rela).

Lemmer ER, Welch JL, Tsai T, Keck-Waggoner CL, Huh C, Zimonjic DB, Popescu NC, Thorgeirsson SS.

Cytogenet Cell Genet. 2000;89(1-2):129-32.

PMID:
10894954
49.

Assignment of WDR7 (alias TRAG, TGF-beta resistance associated gene) to orthologous regions of human chromosome 18q21.1-->q22 and mouse chromosome 18D.1-E.3 by fluorescence in situ hybridization.

Sanders S, Keck-Waggoner CL, Zimonjic DB, Popescu NC, Thorgeirsson SS.

Cytogenet Cell Genet. 2000;88(3-4):324-5. No abstract available.

PMID:
10828621
50.

Characterization of Ly-6M, a novel member of the Ly-6 family of hematopoietic proteins.

Patterson JM, Johnson MH, Zimonjic DB, Graubert TA.

Blood. 2000 May 15;95(10):3125-32.

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