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Items: 37


Intrathymic AAV gene transfer rapidly restores thymic function and long-term persistence of gene-corrected T cells.

Pouzolles M, Machado A, Guilbaud M, Irla M, Gailhac S, Barennes P, Cesana D, Calabria A, Benedicenti F, Sergé A, Raman I, Li QZ, Montini E, Klatzmann D, Adjali O, Taylor N, Zimmermann VS.

J Allergy Clin Immunol. 2019 Sep 9. pii: S0091-6749(19)31171-6. doi: 10.1016/j.jaci.2019.08.029. [Epub ahead of print]


Single-cell mapping of the thymic stroma identifies IL-25-producing tuft epithelial cells.

Bornstein C, Nevo S, Giladi A, Kadouri N, Pouzolles M, Gerbe F, David E, Machado A, Chuprin A, Tóth B, Goldberg O, Itzkovitz S, Taylor N, Jay P, Zimmermann VS, Abramson J, Amit I.

Nature. 2018 Jul;559(7715):622-626. doi: 10.1038/s41586-018-0346-1. Epub 2018 Jul 18.


Resveratrol stimulates the metabolic reprogramming of human CD4+ T cells to enhance effector function.

Craveiro M, Cretenet G, Mongellaz C, Matias MI, Caron O, de Lima MCP, Zimmermann VS, Solary E, Dardalhon V, Dulić V, Taylor N.

Sci Signal. 2017 Oct 17;10(501). pii: eaal3024. doi: 10.1126/scisignal.aal3024.


Hematopoietic stem cell lineage specification.

Pouzolles M, Oburoglu L, Taylor N, Zimmermann VS.

Curr Opin Hematol. 2016 Jul;23(4):311-7. doi: 10.1097/MOH.0000000000000260. Review.


Intestinal epithelial tuft cells initiate type 2 mucosal immunity to helminth parasites.

Gerbe F, Sidot E, Smyth DJ, Ohmoto M, Matsumoto I, Dardalhon V, Cesses P, Garnier L, Pouzolles M, Brulin B, Bruschi M, Harcus Y, Zimmermann VS, Taylor N, Maizels RM, Jay P.

Nature. 2016 Jan 14;529(7585):226-30. doi: 10.1038/nature16527.


Glucose and glutamine metabolism regulate human hematopoietic stem cell lineage specification.

Oburoglu L, Tardito S, Fritz V, de Barros SC, Merida P, Craveiro M, Mamede J, Cretenet G, Mongellaz C, An X, Klysz D, Touhami J, Boyer-Clavel M, Battini JL, Dardalhon V, Zimmermann VS, Mohandas N, Gottlieb E, Sitbon M, Kinet S, Taylor N.

Cell Stem Cell. 2014 Aug 7;15(2):169-84. doi: 10.1016/j.stem.2014.06.002. Epub 2014 Jun 19. Erratum in: Cell Stem Cell. 2014 Nov 6;15(5):666-8.


Ikaros' suspended flight in the thymus.

Taylor N, Zimmermann VS.

Blood. 2013 Oct 3;122(14):2291-2. doi: 10.1182/blood-2013-08-519835. No abstract available.


Concise review: hematopoietic stem cell transplantation: targeting the thymus.

De Barros SC, Zimmermann VS, Taylor N.

Stem Cells. 2013 Jul;31(7):1245-51. doi: 10.1002/stem.1378. Review.


Intrathymic progenitor cell transplantation across histocompatibility barriers results in the persistence of early thymic progenitors and T-cell differentiation.

de Barros SC, Vicente R, Chebli K, Jacquet C, Zimmermann VS, Taylor N.

Blood. 2013 Mar 14;121(11):2144-53. doi: 10.1182/blood-2012-08-447417. Epub 2013 Jan 10.


Molecular and cellular basis of T cell lineage commitment.

Vicente R, Swainson L, Marty-Grès S, De Barros SC, Kinet S, Zimmermann VS, Taylor N.

Semin Immunol. 2010 Oct;22(5):270-5. doi: 10.1016/j.smim.2010.04.016. Epub 2010 Jul 13. Review.


Intrathymic transplantation of bone marrow-derived progenitors provides long-term thymopoiesis.

Vicente R, Adjali O, Jacquet C, Zimmermann VS, Taylor N.

Blood. 2010 Mar 11;115(10):1913-20. doi: 10.1182/blood-2009-06-229724. Epub 2009 Dec 29.


Efficient intrathymic gene transfer following in situ administration of a rAAV serotype 8 vector in mice and nonhuman primates.

Moreau A, Vicente R, Dubreil L, Adjali O, Podevin G, Jacquet C, Deschamps JY, Klatzmann D, Cherel Y, Taylor N, Moullier P, Zimmermann VS.

Mol Ther. 2009 Mar;17(3):472-9. doi: 10.1038/mt.2008.272. Epub 2008 Dec 16.


Tumors hamper the immunogenic competence of CD4+ T cell-directed dendritic cell vaccination.

Zimmermann VS, Casati A, Schiering C, Caserta S, Hess Michelini R, Basso V, Mondino A.

J Immunol. 2007 Sep 1;179(5):2899-909.


Requirement for dendritic cells in the establishment of anti-phospholipid antibodies.

Bondanza A, Rovere-Querini P, Zimmermann VS, Balestrieri G, Tincani A, Sabbadini MG, Manfredi AA.

Autoimmunity. 2007 Jun;40(4):302-6.


Intrathymic administration of hematopoietic progenitor cells enhances T cell reconstitution in ZAP-70 severe combined immunodeficiency.

Adjali O, Vicente RR, Ferrand C, Jacquet C, Mongellaz C, Tiberghien P, Chebli K, Zimmermann VS, Taylor N.

Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13586-91. Epub 2005 Sep 7.


Phenotype and homing of CD4 tumor-specific T cells is modulated by tumor bulk.

Benigni F, Zimmermann VS, Hugues S, Caserta S, Basso V, Rivino L, Ingulli E, Malherbe L, Glaichenhaus N, Mondino A.

J Immunol. 2005 Jul 15;175(2):739-48.


Immune surveillance and anti-tumor immune responses: an anatomical perspective.

Zimmermann VS, Benigni F, Mondino A.

Immunol Lett. 2005 Apr 15;98(1):1-8. Review.


The immunogenicity of dendritic cell-based vaccines is not hampered by doxorubicin and melphalan administration.

Casati A, Zimmermann VS, Benigni F, Bertilaccio MT, Bellone M, Mondino A.

J Immunol. 2005 Mar 15;174(6):3317-25.


Inhibition of phosphatidylserine recognition heightens the immunogenicity of irradiated lymphoma cells in vivo.

Bondanza A, Zimmermann VS, Rovere-Querini P, Turnay J, Dumitriu IE, Stach CM, Voll RE, Gaipl US, Bertling W, Pöschl E, Kalden JR, Manfredi AA, Herrmann M.

J Exp Med. 2004 Nov 1;200(9):1157-65. Epub 2004 Oct 25.


Requirement of dying cells and environmental adjuvants for the induction of autoimmunity.

Bondanza A, Zimmermann VS, Dell'Antonio G, Cin ED, Balestrieri G, Tincani A, Amoura Z, Piette JC, Sabbadini MG, Rovere-Querini P, Manfredi AA.

Arthritis Rheum. 2004 May;50(5):1549-60.


TNF-alpha coupled to membrane of apoptotic cells favors the cross-priming to melanoma antigens.

Zimmermann VS, Bondanza A, Monno A, Rovere-Querini P, Corti A, Manfredi AA.

J Immunol. 2004 Feb 15;172(4):2643-50.


Characterisation of functional biotinylated TNF-alpha targeted to the membrane of apoptotic melanoma cells.

Zimmermann VS, Bondanza A, Rovere-Querini P, Colombo B, Sacchi A, Fascio U, Corti A, Manfredi AA.

J Immunol Methods. 2003 May 1;276(1-2):79-87.


Cutting edge: dissociation between autoimmune response and clinical disease after vaccination with dendritic cells.

Bondanza A, Zimmermann VS, Dell'Antonio G, Dal Cin E, Capobianco A, Sabbadini MG, Manfredi AA, Rovere-Querini P.

J Immunol. 2003 Jan 1;170(1):24-7.


Anti-beta2 glycoprotein I antibodies cause inflammation and recruit dendritic cells in platelet clearance.

Bondanza A, Manfredi AA, Zimmermann VS, Iannacone M, Tincani A, Balestrieri G, Sabbadini MG, Querini PR.

Thromb Haemost. 2001 Nov;86(5):1257-63.


Cytokine secretion associated with the clearance of apoptotic bodies in renal cell carcinoma patients.

Bondanza A, Rovere P, Borri A, Caremoli ER, Guidetti A, Citterio G, Consogno G, Zimmermann VS, Rugarli C, Manfredi AA.

Int J Cancer. 2001 Mar 1;91(5):713-7.


The long pentraxin PTX3 binds to apoptotic cells and regulates their clearance by antigen-presenting dendritic cells.

Rovere P, Peri G, Fazzini F, Bottazzi B, Doni A, Bondanza A, Zimmermann VS, Garlanda C, Fascio U, Sabbadini MG, Rugarli C, Mantovani A, Manfredi AA.

Blood. 2000 Dec 15;96(13):4300-6.


Anti-beta2 glycoprotein I antibodies prevent the De-activation of platelets and sustain their phagocytic clearance.

Bondanza A, Sabbadini MG, Pellegatta F, Zimmermann VS, Tincani A, Balestrieri G, Manfredi AA, Rovere P.

J Autoimmun. 2000 Dec;15(4):469-77.


Remnants of suicidal cells fostering systemic autoaggression. Apoptosis in the origin and maintenance of autoimmunity.

Rovere P, Sabbadini MG, Fazzini F, Bondanza A, Zimmermann VS, Rugarli C, Manfredi AA.

Arthritis Rheum. 2000 Aug;43(8):1663-72. Review. No abstract available.


Delayed clearance of apoptotic lymphoma cells allows cross-presentation of intracellular antigens by mature dendritic cells.

Rovere P, Sabbadini MG, Vallinoto C, Fascio U, Zimmermann VS, Bondanza A, Ricciardi-Castagnoli P, Manfredi AA.

J Leukoc Biol. 1999 Aug;66(2):345-9.


Presentation of antigens internalized through the B cell receptor requires newly synthesized MHC class II molecules.

Forquet F, Barois N, Machy P, Trucy J, Zimmermann VS, Leserman L, Davoust J.

J Immunol. 1999 Mar 15;162(6):3408-16.


Engagement of B cell receptor regulates the invariant chain-dependent MHC class II presentation pathway.

Zimmermann VS, Rovere P, Trucy J, Serre K, Machy P, Forquet F, Leserman L, Davoust J.

J Immunol. 1999 Mar 1;162(5):2495-502.


Dendritic cells preferentially internalize apoptotic cells opsonized by anti-beta2-glycoprotein I antibodies.

Rovere P, Manfredi AA, Vallinoto C, Zimmermann VS, Fascio U, Balestrieri G, Ricciardi-Castagnoli P, Rugarli C, Tincani A, Sabbadini MG.

J Autoimmun. 1998 Oct;11(5):403-11.


Dendritic cell maturation and antigen presentation in the absence of invariant chain.

Rovere P, Zimmermann VS, Forquet F, Demandolx D, Trucy J, Ricciardi-Castagnoli P, Davoust J.

Proc Natl Acad Sci U S A. 1998 Feb 3;95(3):1067-72.


Maturation stages of mouse dendritic cells in growth factor-dependent long-term cultures.

Winzler C, Rovere P, Rescigno M, Granucci F, Penna G, Adorini L, Zimmermann VS, Davoust J, Ricciardi-Castagnoli P.

J Exp Med. 1997 Jan 20;185(2):317-28.


Differential mRNA expression in untreated and TNF-alpha elicited murine dendritic cells precursors.

Rovere P, Trucy J, Zimmermann VS, Granjeaud S, Rocha D, Nguyen C, Ricciardi-Castagnoli P, Jordan BR, Davoust J.

Adv Exp Med Biol. 1997;417:467-73.


Dendritic cells from mice lacking the invariant chain express high levels of membrane MHC class II molecules in vivo.

Rovere P, Forquet F, Zimmermann VS, Trucy J, Ricciardi-Castagnoli P, Davoust J.

Adv Exp Med Biol. 1997;417:195-201.


Checkpoints and functional stages in DC maturation.

Winzler C, Rovere P, Zimmermann VS, Davoust J, Rescigno M, Citterio S, Ricciardi-Castagnoli P.

Adv Exp Med Biol. 1997;417:59-64. No abstract available.


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