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Systematically Scrutinizing the Impact of Substitution Sites on Thermostability and Detergent Tolerance for Bacillus subtilis Lipase A.

Nutschel C, Fulton A, Zimmermann O, Schwaneberg U, Jaeger KE, Gohlke H.

J Chem Inf Model. 2020 Jan 16. doi: 10.1021/acs.jcim.9b00954. [Epub ahead of print]


Proteotyping of Clostridioides difficile as Alternate Typing Method to Ribotyping Is Able to Distinguish the Ribotypes RT027 and RT176 From Other Ribotypes.

Emele MF, Joppe FM, Riedel T, Overmann J, Rupnik M, Cooper P, Kusumawati RL, Berger FK, Laukien F, Zimmermann O, Bohne W, Groß U, Bader O, Zautner AE.

Front Microbiol. 2019 Sep 10;10:2087. doi: 10.3389/fmicb.2019.02087. eCollection 2019.


Effectiveness of caries-preventing agents on initial carious lesions within the scope of orthodontic therapy.

Park KJ, Kroker T, Groß U, Zimmermann O, Krause F, Haak R, Ziebolz D.

Korean J Orthod. 2019 Jul;49(4):246-253. doi: 10.4041/kjod.2019.49.4.246. Epub 2019 Jul 22.


"First in Man": Case Report of Selective C-Reactive Protein Apheresis in a Patient with Acute ST Segment Elevation Myocardial Infarction.

Ries W, Sheriff A, Heigl F, Zimmermann O, Garlichs CD, Torzewski J.

Case Rep Cardiol. 2018 Nov 6;2018:4767105. doi: 10.1155/2018/4767105. eCollection 2018.


Characterization of a clinical Clostridioides difficile isolate with markedly reduced fidaxomicin susceptibility and a V1143D mutation in rpoB.

Schwanbeck J, Riedel T, Laukien F, Schober I, Oehmig I, Zimmermann O, Overmann J, Groß U, Zautner AE, Bohne W.

J Antimicrob Chemother. 2019 Jan 1;74(1):6-10. doi: 10.1093/jac/dky375.


Prevalence and Strain Characterization of Clostridioides (Clostridium) difficile in Representative Regions of Germany, Ghana, Tanzania and Indonesia - A Comparative Multi-Center Cross-Sectional Study.

Seugendo M, Janssen I, Lang V, Hasibuan I, Bohne W, Cooper P, Daniel R, Gunka K, Kusumawati RL, Mshana SE, von Müller L, Okamo B, Ortlepp JR, Overmann J, Riedel T, Rupnik M, Zimmermann O, Groß U.

Front Microbiol. 2018 Aug 7;9:1843. doi: 10.3389/fmicb.2018.01843. eCollection 2018.


Genomic and phenotypic diversity of Clostridium difficile during long-term sequential recurrences of infection.

Sachsenheimer FE, Yang I, Zimmermann O, Wrede C, Müller LV, Gunka K, Groß U, Suerbaum S.

Int J Med Microbiol. 2018 Apr;308(3):364-377. doi: 10.1016/j.ijmm.2018.02.002. Epub 2018 Feb 21.


Comparative genome and phenotypic analysis of three Clostridioides difficile strains isolated from a single patient provide insight into multiple infection of C. difficile.

Groß U, Brzuszkiewicz E, Gunka K, Starke J, Riedel T, Bunk B, Spröer C, Wetzel D, Poehlein A, Chibani C, Bohne W, Overmann J, Zimmermann O, Daniel R, Liesegang H.

BMC Genomics. 2018 Jan 2;19(1):1. doi: 10.1186/s12864-017-4368-0.


Corynebacterium gottingense sp. nov., isolated from a clinical patient.

Atasayar E, Zimmermann O, Spröer C, Schumann P, Groß U.

Int J Syst Evol Microbiol. 2017 Nov;67(11):4494-4499. doi: 10.1099/ijsem.0.002322. Epub 2017 Sep 27.


High metabolic versatility of different toxigenic and non-toxigenic Clostridioides difficile isolates.

Riedel T, Wetzel D, Hofmann JD, Plorin SPEO, Dannheim H, Berges M, Zimmermann O, Bunk B, Schober I, Spröer C, Liesegang H, Jahn D, Overmann J, Groß U, Neumann-Schaal M.

Int J Med Microbiol. 2017 Sep;307(6):311-320. doi: 10.1016/j.ijmm.2017.05.007. Epub 2017 Jun 1.


Prevalence of pregnancy-relevant infections in a rural setting of Ghana.

Völker F, Cooper P, Bader O, Uy A, Zimmermann O, Lugert R, Groß U.

BMC Pregnancy Childbirth. 2017 Jun 6;17(1):172. doi: 10.1186/s12884-017-1351-3.


Steep rise in norovirus cases and emergence of a new recombinant strain GII.P16-GII.2, Germany, winter 2016.

Niendorf S, Jacobsen S, Faber M, Eis-Hübinger AM, Hofmann J, Zimmermann O, Höhne M, Bock CT.

Euro Surveill. 2017 Jan 26;22(4). pii: 30447. doi: 10.2807/1560-7917.ES.2017.22.4.30447.


Backbone Dihedral Angle Prediction.

Zimmermann O.

Methods Mol Biol. 2017;1484:65-82. doi: 10.1007/978-1-4939-6406-2_7.


Cytotoxic potential of IL-15-activated cytokine-induced killer cells against human neuroblastoma cells.

Cappel C, Huenecke S, Suemmerer A, Erben S, Rettinger E, Pfirrmann V, Heinze A, Zimmermann O, Klingebiel T, Ullrich E, Bader P, Bremm M.

Pediatr Blood Cancer. 2016 Dec;63(12):2230-2239. doi: 10.1002/pbc.26147. Epub 2016 Jul 19.


High prevalence of nontoxigenic Clostridium difficile isolated from hospitalized and non-hospitalized individuals in rural Ghana.

Janssen I, Cooper P, Gunka K, Rupnik M, Wetzel D, Zimmermann O, Groß U.

Int J Med Microbiol. 2016 Dec;306(8):652-656. doi: 10.1016/j.ijmm.2016.09.004. Epub 2016 Sep 24.


In-vitro influence of mycophenolate mofetil (MMF) and Ciclosporin A (CsA) on cytokine induced killer (CIK) cell immunotherapy.

Bremm M, Huenecke S, Zimmermann O, Pfirrmann V, Quaiser A, Bonig H, Soerensen J, Klingebiel T, Rettinger E, Bader P, Cappel C.

J Transl Med. 2016 Sep 13;14:264. doi: 10.1186/s12967-016-1024-4.


Effect of fiber insertion depth on antibacterial efficacy of photodynamic therapy against Enterococcus faecalis in rootcanals.

Rödig T, Endres S, Konietschke F, Zimmermann O, Sydow HG, Wiegand A.

Clin Oral Investig. 2017 Jun;21(5):1753-1759. doi: 10.1007/s00784-016-1948-3. Epub 2016 Sep 3.


Natural zeolites in diet or litter of broilers.

Schneider AF, Almeida DS, Yuri FM, Zimmermann OF, Gerber MW, Gewehr CE.

Br Poult Sci. 2016 Apr;57(2):257-63. doi: 10.1080/00071668.2016.1150962.


Discrete-continuous reaction-diffusion model with mobile point-like sources and sinks.

Kondrat S, Zimmermann O, Wiechert W, von Lieres E.

Eur Phys J E Soft Matter. 2016 Jan;39(1):11. doi: 10.1140/epje/i2016-16011-0. Epub 2016 Jan 29.


Clostridium difficile infections among adults and children in Mwanza/Tanzania: is it an underappreciated pathogen among immunocompromised patients in sub-Saharan Africa?

Seugendo M, Mshana SE, Hokororo A, Okamo B, Mirambo MM, von Müller L, Gunka K, Zimmermann O, Groß U.

New Microbes New Infect. 2015 Oct 9;8:99-102. doi: 10.1016/j.nmni.2015.09.016. eCollection 2015 Nov.


The Reduction in Antibiotic Use in Hospitals.

Scholze K, Wenke M, Schierholz R, Groß U, Bader O, Zimmermann O, Lemmen S, Ortlepp JR.

Dtsch Arztebl Int. 2015 Oct 16;112(42):714-21. doi: 10.3238/arztebl.2015.0714.


Scientific workflow optimization for improved peptide and protein identification.

Holl S, Mohammed Y, Zimmermann O, Palmblad M.

BMC Bioinformatics. 2015 Sep 3;16:284. doi: 10.1186/s12859-015-0714-x.


Large diverticulum of the urinary bladder: A rare cause of deep vein thrombosis with consecutive pulmonary embolism.

Zimmermann O, Torzewski J, Reichenbach-Klinke E, Zenk C.

Can Urol Assoc J. 2015 May-Jun;9(5-6):E321-3. doi: 10.5489/cuaj.2533.


The effect of composition on diffusion of macromolecules in a crowded environment.

Kondrat S, Zimmermann O, Wiechert W, von Lieres E.

Phys Biol. 2015 May 28;12(4):046003. doi: 10.1088/1478-3975/12/4/046003.


Salmonella Typhi meningitis in a 9-year old boy with urinary schistosomiasis: a case report.

Chacha F, Mshana SE, Mirambo MM, Mushi MF, Kabymera R, Gerwing L, Schneiderhan W, Zimmermann O, Groß U.

BMC Res Notes. 2015 Mar 3;8:64. doi: 10.1186/s13104-015-1030-2.


Linezolid resistance in clinical isolates of Staphylococcus epidermidis from German hospitals and characterization of two cfr-carrying plasmids.

Bender J, Strommenger B, Steglich M, Zimmermann O, Fenner I, Lensing C, Dagwadordsch U, Kekulé AS, Werner G, Layer F.

J Antimicrob Chemother. 2015;70(6):1630-8. doi: 10.1093/jac/dkv025. Epub 2015 Mar 3.


Two cases of chronic suppurative otitis media caused by Kerstersia gyiorum in Tanzania: is it an underappreciated pathogen in chronic otitis media?

Mwalutende A, Mshana SE, Mirambo MM, Mushi MF, Chalya PL, Giliyoma JM, Schneiderhan W, Zimmermann O, Groß U.

Int J Infect Dis. 2014 Dec;29:251-3. doi: 10.1016/j.ijid.2014.10.022. Epub 2014 Nov 6.


Comprehensive large-scale assessment of intrinsic protein disorder.

Walsh I, Giollo M, Di Domenico T, Ferrari C, Zimmermann O, Tosatto SC.

Bioinformatics. 2015 Jan 15;31(2):201-8. doi: 10.1093/bioinformatics/btu625. Epub 2014 Sep 21.


Interleukin-2-stimulated natural killer cells are less susceptible to mycophenolate mofetil than non-activated NK cells: possible consequences for immunotherapy.

Brehm C, Huenecke S, Esser R, Kloess S, Quaiser A, Betz S, Zimmermann O, Soerensen J, Passweg JR, Klingebiel T, Schwabe D, Bader P, Koehl U.

Cancer Immunol Immunother. 2014 Aug;63(8):821-33. doi: 10.1007/s00262-014-1556-5. Epub 2014 May 8.


C-reactive protein in human atherogenesis: facts and fiction.

Zimmermann O, Li K, Zaczkiewicz M, Graf M, Liu Z, Torzewski J.

Mediators Inflamm. 2014;2014:561428. doi: 10.1155/2014/561428. Epub 2014 Apr 1. Review.


[Endophthalmitis, liver abscess, and cerebral and pulmonary emboli in a 48-year-old Vietnamese man].

Korsten P, Vasko R, Gross O, Schrempf LE, Zimmermann O, Schulze MH, Müller GA.

Internist (Berl). 2014 Jun;55(6):722-5. doi: 10.1007/s00108-014-3484-z. German.


Effects of easy-to-perform procedures to reduce bacterial colonization with Streptococcus mutans and Staphylococcus aureus on toothbrushes.

Zautner AE, Hage A, Schneider K, Schlösser K, Zimmermann O, Hornecker E, Mausberg RF, Frickmann H, Groß U, Ziebolz D.

Eur J Microbiol Immunol (Bp). 2013 Sep;3(3):204-10. doi: 10.1556/EuJMI.3.2013.3.9. Epub 2013 Sep 23.


Isolated ocular Jarisch-Herxheimer reaction after initiating tuberculostatic therapy in a child.

Neunhöffer H, Gold A, Hoerauf H, Herbort C, Heiligenhaus A, Zimmermann O, Feltgen N.

Int Ophthalmol. 2014 Jun;34(3):675-77.


In-hospital results of transcatheter aortic valve implantation (TAVI) in a district hospital--an approach to treat TAVI patients in rural areas.

Torzewski J, Zimmermann O, Paula J, Fiedermutz M, Li K, Ito W, Karch M, Liu Z, Ruland A, Hüttner I, Osberghaus M, Doll N.

Int J Cardiol. 2013 Oct 12;168(5):4845-6. doi: 10.1016/j.ijcard.2013.07.080. Epub 2013 Aug 7. No abstract available.


Folding of Top7 in unbiased all-atom Monte Carlo simulations.

Mohanty S, Meinke JH, Zimmermann O.

Proteins. 2013 Aug;81(8):1446-56. doi: 10.1002/prot.24295. Epub 2013 Jul 2.


Successful use of mRNA-nucleofection for overexpression of interleukin-10 in murine monocytes/macrophages for anti-inflammatory therapy in a murine model of autoimmune myocarditis.

Zimmermann O, Homann JM, Bangert A, Müller AM, Hristov G, Goeser S, Wiehe JM, Zittrich S, Rottbauer W, Torzewski J, Pfitzer G, Katus HA, Kaya Z.

J Am Heart Assoc. 2012 Dec;1(6):e003293. doi: 10.1161/JAHA.112.003293. Epub 2012 Dec 19.


Rapid discrimination of Salmonella enterica serovar Typhi from other serovars by MALDI-TOF mass spectrometry.

Kuhns M, Zautner AE, Rabsch W, Zimmermann O, Weig M, Bader O, Groß U.

PLoS One. 2012;7(6):e40004. doi: 10.1371/journal.pone.0040004. Epub 2012 Jun 29.


GMP-adapted overexpression of CXCR4 in human mesenchymal stem cells for cardiac repair.

Wiehe JM, Kaya Z, Homann JM, Wöhrle J, Vogt K, Nguyen T, Rottbauer W, Torzewski J, Fekete N, Rojewski M, Schrezenmeier H, Moepps B, Zimmermann O.

Int J Cardiol. 2013 Sep 1;167(5):2073-81. doi: 10.1016/j.ijcard.2012.05.065. Epub 2012 Jun 4.


Surface-associated motility, a common trait of clinical isolates of Acinetobacter baumannii, depends on 1,3-diaminopropane.

Skiebe E, de Berardinis V, Morczinek P, Kerrinnes T, Faber F, Lepka D, Hammer B, Zimmermann O, Ziesing S, Wichelhaus TA, Hunfeld KP, Borgmann S, Gröbner S, Higgins PG, Seifert H, Busse HJ, Witte W, Pfeifer Y, Wilharm G.

Int J Med Microbiol. 2012 Jul;302(3):117-28. doi: 10.1016/j.ijmm.2012.03.003. Epub 2012 May 3.


Comparison of acoustic radiation force impulse imaging with transient elastography for the detection of complications in patients with cirrhosis.

Vermehren J, Polta A, Zimmermann O, Herrmann E, Poynard T, Hofmann WP, Bojunga J, Sarrazin C, Zeuzem S, Friedrich-Rust M.

Liver Int. 2012 May;32(5):852-8. doi: 10.1111/j.1478-3231.2011.02736.x. Epub 2011 Dec 30.


Atrial fibrillation-induced cardiac shock: first manifestation of a congenitally corrected transposition of the great arteries in a 45-year-old man.

Graf M, Zaczkiewicz M, Torzewski J, Zimmermann O.

Case Rep Cardiol. 2012;2012:126764. doi: 10.1155/2012/126764. Epub 2012 Nov 24.


Bacteremia and antimicrobial drug resistance over time, Ghana.

Gross U, Amuzu SK, de Ciman R, Kassimova I, Gross L, Rabsch W, Rosenberg U, Schulze M, Stich A, Zimmermann O.

Emerg Infect Dis. 2011 Oct;17(10):1879-82. doi: 10.3201/eid1710.110327.


Intravenous zanamivir for patients with pneumonitis due to pandemic (H1N1) 2009 influenza virus.

Härter G, Zimmermann O, Maier L, Schubert A, Mertens T, Kern P, Wöhrle J.

Clin Infect Dis. 2010 May 1;50(9):1249-51. doi: 10.1086/651604.


Interferon beta-1b therapy in chronic viral dilated cardiomyopathy--is there a role for specific therapy?

Zimmermann O, Rodewald C, Radermacher M, Vetter M, Wiehe JM, Bienek-Ziolkowski M, Hombach V, Torzewski J.

J Card Fail. 2010 Apr;16(4):348-56. doi: 10.1016/j.cardfail.2009.12.016. Epub 2010 Feb 7.


Characterization of MRI contrast agent-loaded polymeric nanocapsules as versatile vehicle for targeted imaging.

Sharma S, Paiphansiri U, Hombach V, Mailänder V, Zimmermann O, Landfester K, Rasche V.

Contrast Media Mol Imaging. 2010 Mar-Apr;5(2):59-69. doi: 10.1002/cmmi.364.


Electrocardiographic and cardiac magnetic resonance imaging parameters as predictors of a worse outcome in patients with idiopathic dilated cardiomyopathy.

Hombach V, Merkle N, Torzewski J, Kraus JM, Kunze M, Zimmermann O, Kestler HA, Wöhrle J.

Eur Heart J. 2009 Aug;30(16):2011-8. doi: 10.1093/eurheartj/ehp293. Epub 2009 Jul 24.


Myocardial inflammation and non-ischaemic heart failure: is there a role for C-reactive protein?

Zimmermann O, Bienek-Ziolkowski M, Wolf B, Vetter M, Baur R, Mailänder V, Hombach V, Torzewski J.

Basic Res Cardiol. 2009 Sep;104(5):591-9. doi: 10.1007/s00395-009-0026-2. Epub 2009 Apr 3.


LOCUSTRA: accurate prediction of local protein structure using a two-layer support vector machine approach.

Zimmermann O, Hansmann UH.

J Chem Inf Model. 2008 Sep;48(9):1903-8. doi: 10.1021/ci800178a. Epub 2008 Sep 3.


Clostridium difficile toxinotype V, ribotype 078, in animals and humans.

Rupnik M, Widmer A, Zimmermann O, Eckert C, Barbut F.

J Clin Microbiol. 2008 Jun;46(6):2146. doi: 10.1128/JCM.00598-08. Epub 2008 Apr 16. No abstract available.

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