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Clinical and genetic analysis of melanomas arising in acral sites.

Zaremba A, Murali R, Jansen P, Möller I, Sucker A, Paschen A, Zimmer L, Livingstone E, Brinker TJ, Hadaschik E, Franklin C, Roesch A, Ugurel S, Schadendorf D, Griewank KG, Cosgarea I.

Eur J Cancer. 2019 Aug 13;119:66-76. doi: 10.1016/j.ejca.2019.07.008. [Epub ahead of print]


18F-F13640 PET imaging of functional receptors in humans.

Colom M, Costes N, Redouté J, Dailler F, Gobert F, Le Bars D, Billard T, Newman-Tancredi A, Zimmer L.

Eur J Nucl Med Mol Imaging. 2019 Aug 14. doi: 10.1007/s00259-019-04473-7. [Epub ahead of print] No abstract available.


Impact of American Joint Committee on Cancer 8th edition classification on staging and survival of patients with melanoma.

Kanaki T, Stang A, Gutzmer R, Zimmer L, Chorti E, Sucker A, Ugurel S, Hadaschik E, Gräger NS, Satzger I, Schadendorf D, Livingstone E.

Eur J Cancer. 2019 Aug 8;119:18-29. doi: 10.1016/j.ejca.2019.06.011. [Epub ahead of print]


Impact of Procalcitonin Levels Combined with Active Intervention on Antimicrobial Stewardship in a Community Hospital.

Newton JA, Robinson S, Ling CLL, Zimmer L, Kuper K, Trivedi KK.

Open Forum Infect Dis. 2019 Aug 10. pii: ofz355. doi: 10.1093/ofid/ofz355. [Epub ahead of print]


Prognostic factors for pulmonary metastasectomy in malignant melanoma: size matters.

Viehof J, Livingstone E, Loscha E, Stockhammer P, Bankfalvi A, Plönes T, Mardanzai K, Zimmer L, Sucker A, Schadendorf D, Hegedüs B, Aigner C.

Eur J Cardiothorac Surg. 2019 Jul 18. pii: ezz211. doi: 10.1093/ejcts/ezz211. [Epub ahead of print]


Evaluation of Myelin Radiotracers in the Lysolecithin Rat Model of Focal Demyelination: Beware of Pitfalls!

Zhang M, Hugon G, Bouillot C, Bolbos R, Langlois JB, Billard T, Bonnefoi F, Li B, Zimmer L, Chauveau F.

Contrast Media Mol Imaging. 2019 May 29;2019:9294586. doi: 10.1155/2019/9294586. eCollection 2019.


Mild traumatic brain injury in the United States: demographics, brain imaging procedures, health-care utilization and costs.

Pavlov V, Thompson-Leduc P, Zimmer L, Wen J, Shea J, Beyhaghi H, Toback S, Kirson N, Miller M.

Brain Inj. 2019;33(9):1151-1157. doi: 10.1080/02699052.2019.1629022. Epub 2019 Jun 26.


Economic and clinical benefits of early identification of acute kidney injury using a urinary biomarker.

Berdugo MA, Kirson NY, Zimmer L, Beyhaghi H, Toback S, Scarpati LM, Stone MN, Dember R, Tseng-Tham J, Wen J, Miller M.

J Med Econ. 2019 Jul 15:1-9. doi: 10.1080/13696998.2019.1636053. [Epub ahead of print]


Tolerability of BRAF/MEK inhibitor combinations: adverse event evaluation and management.

Heinzerling L, Eigentler TK, Fluck M, Hassel JC, Heller-Schenck D, Leipe J, Pauschinger M, Vogel A, Zimmer L, Gutzmer R.

ESMO Open. 2019 May 23;4(3):e000491. doi: 10.1136/esmoopen-2019-000491. eCollection 2019. Review.


Rural and Remote Registered Nurses' Perceptions of Working Beyond Their Legislated Scope of Practice.

MacLeod MLP, Stewart NJ, Kosteniuk JG, Penz KL, Olynick J, Karunanayake CP, Kilpatrick K, Kulig JC, Martin-Misener R, Koren I, Zimmer LV, Pelt LV, Garraway L.

Nurs Leadersh (Tor Ont). 2019 Mar;32(1):20-29. doi: 10.12927/cjnl.2019.25851.


Meta-Analysis in Metastatic Uveal Melanoma to Determine Progression-Free and Overall Survival Benchmarks: an International Rare Cancers Initiative (IRCI) Ocular Melanoma study.

Khoja L, Atenafu EG, Suciu S, Leyvraz S, Sato T, Marshall E, Keilholz U, Zimmer L, Patel SP, Piperno-Neumann S, Piulats J, Kivelä TT, Pfoehler C, Bhatia S, Huppert P, Van Iersel LBJ, De Vries IJM, Penel N, Vogl T, Cheng T, Fiorentini G, Mouriaux F, Tarhini A, Patel PM, Carvajal R, Joshua AM.

Ann Oncol. 2019 May 31. pii: mdz176. doi: 10.1093/annonc/mdz176. [Epub ahead of print]


Metastatic Merkel cell carcinoma and myasthenia gravis: contraindication for therapy with immune checkpoint inhibitors?

Zaremba A, Chorti E, Jockenhöfer F, Bolz S, Sirin S, Glas M, Becker JC, Ugurel S, Roesch A, Schadendorf D, Livingstone E, Hagenacker T, Zimmer L.

J Immunother Cancer. 2019 May 29;7(1):141. doi: 10.1186/s40425-019-0626-9.


Economic analysis of rapid multiplex polymerase chain reaction testing for meningitis/encephalitis in adult patients.

Duff S, Hasbun R, Balada-Llasat JM, Zimmer L, Bozzette SA, Ginocchio CC.

Infection. 2019 May 20. doi: 10.1007/s15010-019-01320-7. [Epub ahead of print]


MHC class-I downregulation in PD-1/PD-L1 inhibitor refractory Merkel cell carcinoma and its potential reversal by histone deacetylase inhibition: a case series.

Ugurel S, Spassova I, Wohlfarth J, Drusio C, Cherouny A, Melior A, Sucker A, Zimmer L, Ritter C, Schadendorf D, Becker JC.

Cancer Immunol Immunother. 2019 Jun;68(6):983-990. doi: 10.1007/s00262-019-02341-9. Epub 2019 Apr 16.


Checkpoint Inhibitors.

Heinzerling L, de Toni EN, Schett G, Hundorfean G, Zimmer L.

Dtsch Arztebl Int. 2019 Feb 22;116(8):119-126. doi: 10.3238/arztebl.2019.0119.


Treatment in metastatic melanoma-time to re-think.

Schadendorf D, Livingstone E, Zimmer L.

Ann Oncol. 2019 Apr 1;30(4):501-503. doi: 10.1093/annonc/mdz050. No abstract available.


Impact of radiation, systemic therapy and treatment sequencing on survival of patients with melanoma brain metastases.

Rauschenberg R, Bruns J, Brütting J, Daubner D, Lohaus F, Zimmer L, Forschner A, Zips D, Hassel JC, Berking C, Kaehler KC, Utikal J, Gutzmer R, Terheyden P, Meiss F, Rafei-Shamsabadi D, Kiecker F, Debus D, Dabrowski E, Arnold A, Garzarolli M, Kuske M, Beissert S, Löck S, Linn J, Troost EGC, Meier F.

Eur J Cancer. 2019 Mar;110:11-20. doi: 10.1016/j.ejca.2018.12.023. Epub 2019 Feb 7.


Sequence-dependent cross-resistance of combined radiotherapy plus BRAFV600E inhibition in melanoma.

Shannan B, Matschke J, Chauvistré H, Vogel F, Klein D, Meier F, Westphal D, Bruns J, Rauschenberg R, Utikal J, Forschner A, Berking C, Terheyden P, Dabrowski E, Gutzmer R, Rafei-Shamsabadi D, Meiss F, Heinzerling L, Zimmer L, Livingstone E, Váraljai R, Hoewner A, Horn S, Klode J, Stuschke M, Scheffler B, Marchetto A, Sannino G, Grünewald TGP, Schadendorf D, Jendrossek V, Roesch A.

Eur J Cancer. 2019 Mar;109:137-153. doi: 10.1016/j.ejca.2018.12.024. Epub 2019 Feb 2.


Serotonin 5-HT1A Receptor Biased Agonists Induce Different Cerebral Metabolic Responses: A [18F]-Fluorodesoxyglucose Positron Emission Tomography Study in Conscious and Anesthetized Rats.

Levigoureux E, Vidal B, Fieux S, Bouillot C, Emery S, Newman-Tancredi A, Zimmer L.

ACS Chem Neurosci. 2019 Jul 17;10(7):3108-3119. doi: 10.1021/acschemneuro.8b00584. Epub 2019 Jan 7.


Epidemiology of Meningitis and Encephalitis in Infants and Children in the United States, 2011-2014.

Hasbun R, Wootton SH, Rosenthal N, Balada-Llasat JM, Chung J, Duff S, Bozzette S, Zimmer L, Ginocchio CC.

Pediatr Infect Dis J. 2019 Jan;38(1):37-41. doi: 10.1097/INF.0000000000002081.


Myositis and neuromuscular side-effects induced by immune checkpoint inhibitors.

Moreira A, Loquai C, Pföhler C, Kähler KC, Knauss S, Heppt MV, Gutzmer R, Dimitriou F, Meier F, Mitzel-Rink H, Schuler G, Terheyden P, Thoms KM, Türk M, Dummer R, Zimmer L, Schröder R, Heinzerling L.

Eur J Cancer. 2019 Jan;106:12-23. doi: 10.1016/j.ejca.2018.09.033. Epub 2018 Nov 17.


Cost of managing meningitis and encephalitis among infants and children in the United States.

Balada-Llasat JM, Rosenthal N, Hasbun R, Zimmer L, Bozzette S, Duff S, Chung J, Ginocchio CC.

Diagn Microbiol Infect Dis. 2019 Apr;93(4):349-354. doi: 10.1016/j.diagmicrobio.2018.10.012. Epub 2018 Oct 27.


Paclitaxel with or without trametinib or pazopanib in advanced wild-type BRAF melanoma (PACMEL): a multicentre, open-label, randomised, controlled phase II trial.

Urbonas V, Schadendorf D, Zimmer L, Danson S, Marshall E, Corrie P, Wheater M, Plummer E, Mauch C, Scudder C, Goff M, Love SB, Mohammed SB, Middleton MR.

Ann Oncol. 2019 Feb 1;30(2):317-324. doi: 10.1093/annonc/mdy500.


Evaluation of [18 F]2FP3 in pigs and non-human primates.

Hansen HD, Constantinescu CC, Barret O, Herth MM, Magnussen JH, Lehel S, Dyssegaard A, Colomb J, Billard T, Zimmer L, Tamagnan G, Knudsen GM.

J Labelled Comp Radiopharm. 2019 Jan;62(1):34-42. doi: 10.1002/jlcr.3692. Epub 2018 Dec 6.


Clinical experience with combination BRAF/MEK inhibitors for melanoma with brain metastases: a real-life multicenter study.

Drago JZ, Lawrence D, Livingstone E, Zimmer L, Chen T, Giobbie-Hurder A, Amann VC, Mangana J, Siano M, Zippelius A, Dummer R, Goldinger SM, Sullivan RJ.

Melanoma Res. 2019 Feb;29(1):65-69. doi: 10.1097/CMR.0000000000000527.


Anti-PD-1/PD-L1 immunotherapy in patients with solid organ transplant, HIV or hepatitis B/C infection.

Tio M, Rai R, Ezeoke OM, McQuade JL, Zimmer L, Khoo C, Park JJ, Spain L, Turajlic S, Ardolino L, Yip D, Goldinger SM, Cohen JV, Millward M, Atkinson V, Kane AY, Ascierto PA, Garbe C, Gutzmer R, Johnson DB, Rizvi HA, Joshua AM, Hellmann MD, Long GV, Menzies AM.

Eur J Cancer. 2018 Nov;104:137-144. doi: 10.1016/j.ejca.2018.09.017. Epub 2018 Oct 20.


The efficacy of re-challenge with BRAF inhibitors after previous progression to BRAF inhibitors in melanoma: A retrospective multicenter study.

Tietze JK, Forschner A, Loquai C, Mitzel-Rink H, Zimmer L, Meiss F, Rafei-Shamsabadi D, Utikal J, Bergmann M, Meier F, Kreuzberg N, Schlaak M, Weishaupt C, Pföhler C, Ziemer M, Fluck M, Rainer J, Heppt MV, Berking C.

Oncotarget. 2018 Sep 28;9(76):34336-34346. doi: 10.18632/oncotarget.26149. eCollection 2018 Sep 28.


In vivo biased agonism at 5-HT1A receptors: characterisation by simultaneous PET/MR imaging.

Vidal B, Fieux S, Redouté J, Villien M, Bonnefoi F, Le Bars D, Newman-Tancredi A, Costes N, Zimmer L.

Neuropsychopharmacology. 2018 Oct;43(11):2310-2319. doi: 10.1038/s41386-018-0145-2. Epub 2018 Jul 6.


In Silico, in Vitro, and in Vivo Evaluation of New Candidates for α-Synuclein PET Imaging.

Verdurand M, Levigoureux E, Zeinyeh W, Berthier L, Mendjel-Herda M, Cadarossanesaib F, Bouillot C, Iecker T, Terreux R, Lancelot S, Chauveau F, Billard T, Zimmer L.

Mol Pharm. 2018 Aug 6;15(8):3153-3166. doi: 10.1021/acs.molpharmaceut.8b00229. Epub 2018 Jul 25.


Patterns of disease control and survival in patients with melanoma brain metastases undergoing immune-checkpoint blockade.

Milsch L, Gesierich A, Kreft S, Livingstone E, Zimmer L, Goebeler M, Schadendorf D, Schilling B.

Eur J Cancer. 2018 Aug;99:58-65. doi: 10.1016/j.ejca.2018.05.012. Epub 2018 Jun 12.


Bioaccessibility of phenolic compounds, lutein, and bioelements of preparations containing Chlorella vulgaris in artificial digestive juices.

Muszyńska B, Krakowska A, Lazur J, Jękot B, Zimmer Ł, Szewczyk A, Sułkowska-Ziaja K, Poleszak E, Opoka W.

J Appl Phycol. 2018;30(3):1629-1640. doi: 10.1007/s10811-017-1357-2. Epub 2017 Dec 6.


Benzodiazepine dose reduction in prisoner patients: 15 years' teamwork between psychiatrists and pharmacists.

Cabelguenne D, Picard C, Lalande L, Jonker J, Sautereau M, Meunier F, Zimmer L.

J Clin Pharm Ther. 2018 Dec;43(6):807-812. doi: 10.1111/jcpt.12709. Epub 2018 May 25.


PET imaging of the influence of physiological and pathological α-synuclein on dopaminergic and serotonergic neurotransmission in mouse models.

Levigoureux E, Bouillot C, Baron T, Zimmer L, Lancelot S.

CNS Neurosci Ther. 2019 Jan;25(1):57-68. doi: 10.1111/cns.12978. Epub 2018 May 20.


18F-F13640 preclinical evaluation in rodent, cat and primate as a 5-HT1A receptor agonist for PET neuroimaging.

Vidal B, Fieux S, Colom M, Billard T, Bouillot C, Barret O, Constantinescu C, Tamagnan G, Newman-Tancredi A, Zimmer L.

Brain Struct Funct. 2018 Jul;223(6):2973-2988. doi: 10.1007/s00429-018-1672-7. Epub 2018 May 5.


Procalcitonin guidance in patients with lower respiratory tract infections: a systematic review and meta-analysis.

Hey J, Thompson-Leduc P, Kirson NY, Zimmer L, Wilkins D, Rice B, Iankova I, Krause A, Schonfeld SA, DeBrase CR, Bozzette S, Schuetz P.

Clin Chem Lab Med. 2018 Jul 26;56(8):1200-1209. doi: 10.1515/cclm-2018-0126.


Cost of managing meningitis and encephalitis among adult patients in the United States of America.

Balada-Llasat JM, Rosenthal N, Hasbun R, Zimmer L, Ginocchio CC, Duff S, Allison J, Bozzette S.

Int J Infect Dis. 2018 Jun;71:117-121. doi: 10.1016/j.ijid.2018.04.799. Epub 2018 Apr 24.


Incidence of epistaxis after endoscopic pituitary surgery: Proposed treatment algorithm.

Zimmer LA, Andaluz N.

Ear Nose Throat J. 2018 Mar;97(3):E44-E48.


Amyloid-Beta Radiotracer [18F]BF-227 Does Not Bind to Cytoplasmic Glial Inclusions of Postmortem Multiple System Atrophy Brain Tissue.

Verdurand M, Levigoureux E, Lancelot S, Zeinyeh W, Billard T, Quadrio I, Perret-Liaudet A, Zimmer L, Chauveau F.

Contrast Media Mol Imaging. 2018 Feb 6;2018:9165458. doi: 10.1155/2018/9165458. eCollection 2018.


[All you need to know about methylphenidate (and dared not ask)].

Zimmer L, Fourneret P.

Arch Pediatr. 2018 Apr;25(3):229-235. doi: 10.1016/j.arcped.2018.01.002. Epub 2018 Mar 12. French.


Ipilimumab in metastatic melanoma patients with pre-existing autoimmune disorders.

Kähler KC, Eigentler TK, Gesierich A, Heinzerling L, Loquai C, Meier F, Meiss F, Pföhler C, Schlaak M, Terheyden P, Thoms KM, Ziemer M, Zimmer L, Gutzmer R; German Dermatologic Cooperative Oncology Group (DeCOG).

Cancer Immunol Immunother. 2018 May;67(5):825-834. doi: 10.1007/s00262-018-2134-z. Epub 2018 Feb 27.


Ozone Atmospheric Pollution and Alzheimer's Disease: From Epidemiological Facts to Molecular Mechanisms.

Croze ML, Zimmer L.

J Alzheimers Dis. 2018;62(2):503-522. doi: 10.3233/JAD-170857. Review.


Dose-dependent toxicity of ipilimumab in metastatic melanoma.

Olischewsky A, De Schrijver S, Bankfalvi A, Wetter A, Zimmer L, Livingstone E, Schadendorf D, Ugurel S.

Eur J Cancer. 2018 May;95:104-108. doi: 10.1016/j.ejca.2018.01.088. Epub 2018 Feb 21. No abstract available.


Clinical outcome of concomitant vs interrupted BRAF inhibitor therapy during radiotherapy in melanoma patients.

Hecht M, Meier F, Zimmer L, Polat B, Loquai C, Weishaupt C, Forschner A, Gutzmer R, Utikal JS, Goldinger SM, Geier M, Hassel JC, Balermpas P, Kiecker F, Rauschenberg R, Dietrich U, Clemens P, Berking C, Grabenbauer G, Schadendorf D, Grabbe S, Schuler G, Fietkau R, Distel LV, Heinzerling L.

Br J Cancer. 2018 Mar 20;118(6):785-792. doi: 10.1038/bjc.2017.489. Epub 2018 Feb 13.


Economic analysis of rapid multiplex polymerase chain reaction testing for meningitis/encephalitis in pediatric patients.

Duff S, Hasbun R, Ginocchio CC, Balada-Llasat JM, Zimmer L, Bozzette SA.

Future Microbiol. 2018 May;13:617-629. doi: 10.2217/fmb-2017-0238. Epub 2018 Jan 10.


Progression patterns under BRAF inhibitor treatment and treatment beyond progression in patients with metastatic melanoma.

Hassel JC, Buder-Bakhaya K, Bender C, Zimmer L, Weide B, Loquai C, Ugurel S, Slynko A, Gutzmer R; German Dermatooncology Group (DeCOG/ADO).

Cancer Med. 2018 Jan;7(1):95-104. doi: 10.1002/cam4.1267. Epub 2017 Dec 20.


Sebaceous tumours: more than skin deep.

Jockenhöfer F, Schimming TT, Schaller J, Moege J, Livingstone E, Salva KA, Zimmer L, Schadendorf D, Rösch A.

Gut. 2018 Nov;67(11):1957. doi: 10.1136/gutjnl-2017-315472. Epub 2017 Dec 15.


Endoscopic transorbital superior eyelid approach: anatomical study from a neurosurgical perspective.

Di Somma A, Andaluz N, Cavallo LM, de Notaris M, Dallan I, Solari D, Zimmer LA, Keller JT, Zuccarello M, Prats-Galino A, Cappabianca P.

J Neurosurg. 2018 Nov 1;129(5):1203-1216. doi: 10.3171/2017.4.JNS162749.


Refining Operative Strategies for Optic Nerve Decompression: A Morphometric Analysis of Transcranial and Endoscopic Endonasal Techniques Using Clinical Parameters.

Gogela SL, Zimmer LA, Keller JT, Andaluz N.

Oper Neurosurg (Hagerstown). 2018 Mar 1;14(3):295-302. doi: 10.1093/ons/opx093.


The in Vitro Actions of Loxapine on Dopaminergic and Serotonergic Receptors. Time to Consider Atypical Classification of This Antipsychotic Drug?

Ferreri F, Drapier D, Baloche E, Ouzid M, Zimmer L, Llorca PM.

Int J Neuropsychopharmacol. 2018 Apr 1;21(4):355-360. doi: 10.1093/ijnp/pyx102.


Cytomegalovirus reactivation in patients with refractory checkpoint inhibitor-induced colitis.

Franklin C, Rooms I, Fiedler M, Reis H, Milsch L, Herz S, Livingstone E, Zimmer L, Schmid KW, Dittmer U, Schadendorf D, Schilling B.

Eur J Cancer. 2017 Nov;86:248-256. doi: 10.1016/j.ejca.2017.09.019. Epub 2017 Oct 19.


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