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Items: 1 to 50 of 363

1.

Drug-induced sarcoidosis-like reaction in adjuvant immunotherapy: Increased rate and mimicker of metastasis.

Chorti E, Kanaki T, Zimmer L, Hadaschik E, Ugurel S, Gratsias E, Roesch A, Bonella F, Wessendorf TE, Wälscher J, Theegarten D, Schadendorf D, Livingstone E.

Eur J Cancer. 2020 Apr 2;131:18-26. doi: 10.1016/j.ejca.2020.02.024. [Epub ahead of print]

PMID:
32248071
2.

Combination immunotherapy with anti-PD-L1 antibody and depletion of regulatory T cells during acute viral infections results in improved virus control but lethal immunopathology.

David P, Drabczyk-Pluta M, Pastille E, Knuschke T, Werner T, Honke N, Megger DA, Akhmetzyanova I, Shaabani N, Eyking-Singer A, Cario E, Kershaw O, Gruber AD, Tenbusch M, Dietze KK, Trilling M, Liu J, Schadendorf D, Streeck H, Lang KS, Xie Y, Zimmer L, Sitek B, Paschen A, Westendorf AM, Dittmer U, Zelinskyy G.

PLoS Pathog. 2020 Mar 30;16(3):e1008340. doi: 10.1371/journal.ppat.1008340. eCollection 2020 Mar.

3.

Combined immunotherapy with nivolumab and ipilimumab with and without local therapy in patients with melanoma brain metastasis: a DeCOG* study in 380 patients.

Amaral T, Kiecker F, Schaefer S, Stege H, Kaehler K, Terheyden P, Gesierich A, Gutzmer R, Haferkamp S, Uttikal J, Berking C, Rafei-Shamsabadi D, Reinhardt L, Meier F, Karoglan A, Posch C, Gambichler T, Pfoehler C, Thoms K, Tietze J, Debus D, Herbst R, Emmert S, Loquai C, Hassel JC, Meiss F, Tueting T, Heinrich V, Eigentler T, Garbe C, Zimmer L; *German Dermatological Cooperative Oncology Group.

J Immunother Cancer. 2020 Mar;8(1). pii: e000333. doi: 10.1136/jitc-2019-000333.

4.

[Malignant melanoma].

Lodde G, Zimmer L, Livingstone E, Schadendorf D, Ugurel S.

Pathologe. 2020 Mar 23. doi: 10.1007/s00292-020-00776-x. [Epub ahead of print] German.

PMID:
32206873
5.

Survival of patients with advanced metastatic melanoma: The impact of MAP kinase pathway inhibition and immune checkpoint inhibition - Update 2019.

Ugurel S, Röhmel J, Ascierto PA, Becker JC, Flaherty KT, Grob JJ, Hauschild A, Larkin J, Livingstone E, Long GV, Lorigan P, McArthur GA, Ribas A, Robert C, Zimmer L, Schadendorf D, Garbe C.

Eur J Cancer. 2020 Mar 13;130:126-138. doi: 10.1016/j.ejca.2020.02.021. [Epub ahead of print]

PMID:
32179447
6.

Extended Anterior Petrosectomy Through the Transcranial Middle Fossa Approach and Extended Endoscopic Transsphenoidal-Transclival Approach: Qualitative and Quantitative Anatomic Analysis.

Hasanbelliu A, Andaluz N, Di Somma A, Keller JT, Zimmer LA, Samy RN, Pensak ML, Zuccarello M.

World Neurosurg. 2020 Mar 4. pii: S1878-8750(20)30402-2. doi: 10.1016/j.wneu.2020.02.127. [Epub ahead of print]

PMID:
32145421
7.

GNAQ and GNA11 mutant non-uveal melanoma, a subtype distinct from both cutaneous and uveal melanoma.

Livingstone E, Zaremba A, Horn S, Ugurel S, Casalini B, Schlaak M, Hassel JC, Herbst R, Utikal JS, Weide B, Gutzmer R, Meier F, Koelsche C, Hadaschik E, Sucker A, Reis H, Merkelbach-Bruse S, Siewert M, Sahm F, von Deimling A, Cosgarea I, Zimmer L, Schadendorf D, Schilling B, Griewank KG.

Br J Dermatol. 2020 Feb 16. doi: 10.1111/bjd.18947. [Epub ahead of print]

PMID:
32064597
8.

Preclinical validation of [18F]2FNQ1P as a specific PET radiotracer of 5-HT6 receptors in rat, pig, non-human primate and human brain tissue.

Emery S, Fieux S, Vidal B, Courault P, Bouvard S, Tourvieille C, Iecker T, Billard T, Zimmer L, Lancelot S.

Nucl Med Biol. 2020 Jan 22;82-83:57-63. doi: 10.1016/j.nucmedbio.2020.01.006. [Epub ahead of print]

PMID:
32006785
9.

Mass Spectrometry Evaluation of Biomarkers in the Vitreous Fluid in Gaucher Disease Type 3 with Disease Progression Despite Long-Term Treatment.

Mhanni A, Boutin M, Stockl F, Johnston J, Barnes J, Duerksen D, Zimmer L, Auray-Blais C, Rockman-Greenberg C.

Diagnostics (Basel). 2020 Jan 26;10(2). pii: E69. doi: 10.3390/diagnostics10020069.

10.

Elevated baseline serum PD-1 or PD-L1 predicts poor outcome of PD-1 inhibition therapy in metastatic melanoma.

Ugurel S, Schadendorf D, Horny K, Sucker A, Schramm S, Utikal J, Pföhler C, Herbst R, Schilling B, Blank C, Becker JC, Paschen A, Zimmer L, Livingstone E, Horn PA, Rebmann V.

Ann Oncol. 2020 Jan;31(1):144-152. doi: 10.1016/j.annonc.2019.09.005.

PMID:
31912789
11.

Contrast Media & Molecular Imaging, a Journal at the Crossroads of the Scientific and Medical Disciplines of Biomedical Imaging.

Zimmer L.

Contrast Media Mol Imaging. 2019 Dec 9;2019:7213829. doi: 10.1155/2019/7213829. eCollection 2019. No abstract available.

12.

Supraorbital vs Endo-Orbital Routes to the Lateral Skull Base: A Quantitative and Qualitative Anatomic Study.

Di Somma A, Andaluz N, Cavallo LM, Keller JT, Solari D, Zimmer LA, de Notaris M, Zuccarello M, Cappabianca P.

Oper Neurosurg (Hagerstown). 2018 Nov 1;15(5):567-576. doi: 10.1093/ons/opx256.

PMID:
31860716
13.

[PET imaging for better understanding of normal and pathological neurotransmission].

Zimmer L.

Biol Aujourdhui. 2019;213(3-4):109-120. doi: 10.1051/jbio/2019025. Epub 2019 Dec 12. French.

PMID:
31829931
14.

Endoscopic endonasal treatment of maxillary nerve (V2) painful neuropathy: cadaveric study with clinical correlation.

Lima F, Andaluz N, Zimmer LA.

Acta Neurochir (Wien). 2020 Jan;162(1):223-229. doi: 10.1007/s00701-019-04126-6. Epub 2019 Dec 6.

PMID:
31811464
15.

Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma.

Liu D, Schilling B, Liu D, Sucker A, Livingstone E, Jerby-Amon L, Zimmer L, Gutzmer R, Satzger I, Loquai C, Grabbe S, Vokes N, Margolis CA, Conway J, He MX, Elmarakeby H, Dietlein F, Miao D, Tracy A, Gogas H, Goldinger SM, Utikal J, Blank CU, Rauschenberg R, von Bubnoff D, Krackhardt A, Weide B, Haferkamp S, Kiecker F, Izar B, Garraway L, Regev A, Flaherty K, Paschen A, Van Allen EM, Schadendorf D.

Nat Med. 2019 Dec;25(12):1916-1927. doi: 10.1038/s41591-019-0654-5. Epub 2019 Dec 2.

16.

Pharmacological MRI to investigate the functional selectivity of 5-HT1A receptor biased agonists.

Vidal B, Bolbos R, Redouté J, Langlois JB, Costes N, Newman-Tancredi A, Zimmer L.

Neuropharmacology. 2019 Nov 26:107867. doi: 10.1016/j.neuropharm.2019.107867. [Epub ahead of print]

PMID:
31783063
17.

[Malignant melanoma].

Lodde G, Zimmer L, Livingstone E, Schadendorf D, Ugurel S.

Hautarzt. 2020 Jan;71(1):63-77. doi: 10.1007/s00105-019-04514-0. German.

PMID:
31773173
18.

Combined immune checkpoint blockade for metastatic uveal melanoma: a retrospective, multi-center study.

Heppt MV, Amaral T, Kähler KC, Heinzerling L, Hassel JC, Meissner M, Kreuzberg N, Loquai C, Reinhardt L, Utikal J, Dabrowski E, Gesierich A, Pföhler C, Terheyden P, Thoms KM, Zimmer L, Eigentler TK, Kirchberger MC, Stege HM, Meier F, Schlaak M, Berking C.

J Immunother Cancer. 2019 Nov 13;7(1):299. doi: 10.1186/s40425-019-0800-0.

19.

Is There a Role for GPCR Agonist Radiotracers in PET Neuroimaging?

Colom M, Vidal B, Zimmer L.

Front Mol Neurosci. 2019 Oct 18;12:255. doi: 10.3389/fnmol.2019.00255. eCollection 2019. Review.

20.

Chronic stress, work-related daily challenges and medicolegal investigations: a cross-sectional study among German general practitioners.

Kersting C, Zimmer L, Thielmann A, Weltermann B.

BMC Fam Pract. 2019 Oct 24;20(1):143. doi: 10.1186/s12875-019-1032-6.

21.

Simultaneous primary cancer occurrence of melanoma and pulmonary adenocarcinoma in leptomeningeal metastases: a case report.

Stoppek AK, Kebir S, Junker A, Keyvani K, Zülow S, Lazaridis L, Schmidt T, Pierscianek D, Stuschke M, Sure U, Kleinschnitz C, Scheffler B, Zimmer L, Glas M.

BMC Cancer. 2019 Oct 23;19(1):995. doi: 10.1186/s12885-019-6183-2.

22.

Targeted Therapy in Advanced Melanoma With Rare BRAF Mutations.

Menzer C, Menzies AM, Carlino MS, Reijers I, Groen EJ, Eigentler T, de Groot JWB, van der Veldt AAM, Johnson DB, Meiss F, Schlaak M, Schilling B, Westgeest HM, Gutzmer R, Pföhler C, Meier F, Zimmer L, Suijkerbuijk KPM, Haalck T, Thoms KM, Herbschleb K, Leichsenring J, Menzer A, Kopp-Schneider A, Long GV, Kefford R, Enk A, Blank CU, Hassel JC.

J Clin Oncol. 2019 Nov 20;37(33):3142-3151. doi: 10.1200/JCO.19.00489. Epub 2019 Oct 3.

PMID:
31580757
23.

[Ensuring safety of patients under antipsychotic drugs: Impact of medical and pharmaceutical collaboration at prison].

Picard C, Lalande L, Bertin C, Abel-Coindoz C, Mauchauffée A, Giret G, Zimmer L, Cabelguenne D.

Encephale. 2019 Dec;45(6):482-487. doi: 10.1016/j.encep.2019.05.008. Epub 2019 Aug 20. French.

PMID:
31443918
24.

Clinical and genetic analysis of melanomas arising in acral sites.

Zaremba A, Murali R, Jansen P, Möller I, Sucker A, Paschen A, Zimmer L, Livingstone E, Brinker TJ, Hadaschik E, Franklin C, Roesch A, Ugurel S, Schadendorf D, Griewank KG, Cosgarea I.

Eur J Cancer. 2019 Sep;119:66-76. doi: 10.1016/j.ejca.2019.07.008. Epub 2019 Aug 14.

PMID:
31419753
25.

18F-F13640 PET imaging of functional receptors in humans.

Colom M, Costes N, Redouté J, Dailler F, Gobert F, Le Bars D, Billard T, Newman-Tancredi A, Zimmer L.

Eur J Nucl Med Mol Imaging. 2020 Jan;47(1):220-221. doi: 10.1007/s00259-019-04473-7. Epub 2019 Aug 14. No abstract available.

PMID:
31414208
26.

Impact of American Joint Committee on Cancer 8th edition classification on staging and survival of patients with melanoma.

Kanaki T, Stang A, Gutzmer R, Zimmer L, Chorti E, Sucker A, Ugurel S, Hadaschik E, Gräger NS, Satzger I, Schadendorf D, Livingstone E.

Eur J Cancer. 2019 Sep;119:18-29. doi: 10.1016/j.ejca.2019.06.011. Epub 2019 Aug 8.

PMID:
31401470
27.

Impact of Procalcitonin Levels Combined with Active Intervention on Antimicrobial Stewardship in a Community Hospital.

Newton JA, Robinson S, Ling CLL, Zimmer L, Kuper K, Trivedi KK.

Open Forum Infect Dis. 2019 Aug 10. pii: ofz355. doi: 10.1093/ofid/ofz355. [Epub ahead of print]

28.

Prognostic factors for pulmonary metastasectomy in malignant melanoma: size matters.

Viehof J, Livingstone E, Loscha E, Stockhammer P, Bankfalvi A, Plönes T, Mardanzai K, Zimmer L, Sucker A, Schadendorf D, Hegedüs B, Aigner C.

Eur J Cardiothorac Surg. 2019 Dec 1;56(6):1104-1109. doi: 10.1093/ejcts/ezz211.

PMID:
31321422
29.

Evaluation of Myelin Radiotracers in the Lysolecithin Rat Model of Focal Demyelination: Beware of Pitfalls!

Zhang M, Hugon G, Bouillot C, Bolbos R, Langlois JB, Billard T, Bonnefoi F, Li B, Zimmer L, Chauveau F.

Contrast Media Mol Imaging. 2019 May 29;2019:9294586. doi: 10.1155/2019/9294586. eCollection 2019.

30.

Mild traumatic brain injury in the United States: demographics, brain imaging procedures, health-care utilization and costs.

Pavlov V, Thompson-Leduc P, Zimmer L, Wen J, Shea J, Beyhaghi H, Toback S, Kirson N, Miller M.

Brain Inj. 2019;33(9):1151-1157. doi: 10.1080/02699052.2019.1629022. Epub 2019 Jun 26.

PMID:
31241427
31.

Economic and clinical benefits of early identification of acute kidney injury using a urinary biomarker.

Berdugo MA, Kirson NY, Zimmer L, Beyhaghi H, Toback S, Scarpati LM, Stone MN, Dember R, Tseng-Tham J, Wen J, Miller M.

J Med Econ. 2019 Dec;22(12):1281-1289. doi: 10.1080/13696998.2019.1636053. Epub 2019 Jul 15.

PMID:
31234668
32.

Tolerability of BRAF/MEK inhibitor combinations: adverse event evaluation and management.

Heinzerling L, Eigentler TK, Fluck M, Hassel JC, Heller-Schenck D, Leipe J, Pauschinger M, Vogel A, Zimmer L, Gutzmer R.

ESMO Open. 2019 May 23;4(3):e000491. doi: 10.1136/esmoopen-2019-000491. eCollection 2019. Review.

33.

Rural and Remote Registered Nurses' Perceptions of Working Beyond Their Legislated Scope of Practice.

MacLeod MLP, Stewart NJ, Kosteniuk JG, Penz KL, Olynick J, Karunanayake CP, Kilpatrick K, Kulig JC, Martin-Misener R, Koren I, Zimmer LV, Pelt LV, Garraway L.

Nurs Leadersh (Tor Ont). 2019 Mar;32(1):20-29. doi: 10.12927/cjnl.2019.25851.

PMID:
31228342
34.

Meta-analysis in metastatic uveal melanoma to determine progression free and overall survival benchmarks: an international rare cancers initiative (IRCI) ocular melanoma study.

Khoja L, Atenafu EG, Suciu S, Leyvraz S, Sato T, Marshall E, Keilholz U, Zimmer L, Patel SP, Piperno-Neumann S, Piulats J, Kivelä TT, Pfoehler C, Bhatia S, Huppert P, Van Iersel LBJ, De Vries IJM, Penel N, Vogl T, Cheng T, Fiorentini G, Mouriaux F, Tarhini A, Patel PM, Carvajal R, Joshua AM.

Ann Oncol. 2019 Aug 1;30(8):1370-1380. doi: 10.1093/annonc/mdz176.

PMID:
31150059
35.

Metastatic Merkel cell carcinoma and myasthenia gravis: contraindication for therapy with immune checkpoint inhibitors?

Zaremba A, Chorti E, Jockenhöfer F, Bolz S, Sirin S, Glas M, Becker JC, Ugurel S, Roesch A, Schadendorf D, Livingstone E, Hagenacker T, Zimmer L.

J Immunother Cancer. 2019 May 29;7(1):141. doi: 10.1186/s40425-019-0626-9.

36.

Economic analysis of rapid multiplex polymerase chain reaction testing for meningitis/encephalitis in adult patients.

Duff S, Hasbun R, Balada-Llasat JM, Zimmer L, Bozzette SA, Ginocchio CC.

Infection. 2019 Dec;47(6):945-953. doi: 10.1007/s15010-019-01320-7. Epub 2019 May 20.

PMID:
31111325
37.

MHC class-I downregulation in PD-1/PD-L1 inhibitor refractory Merkel cell carcinoma and its potential reversal by histone deacetylase inhibition: a case series.

Ugurel S, Spassova I, Wohlfarth J, Drusio C, Cherouny A, Melior A, Sucker A, Zimmer L, Ritter C, Schadendorf D, Becker JC.

Cancer Immunol Immunother. 2019 Jun;68(6):983-990. doi: 10.1007/s00262-019-02341-9. Epub 2019 Apr 16.

PMID:
30993371
38.

Checkpoint Inhibitors.

Heinzerling L, de Toni EN, Schett G, Hundorfean G, Zimmer L.

Dtsch Arztebl Int. 2019 Feb 22;116(8):119-126. doi: 10.3238/arztebl.2019.0119.

39.

Treatment in metastatic melanoma-time to re-think.

Schadendorf D, Livingstone E, Zimmer L.

Ann Oncol. 2019 Apr 1;30(4):501-503. doi: 10.1093/annonc/mdz050. No abstract available.

40.

Impact of radiation, systemic therapy and treatment sequencing on survival of patients with melanoma brain metastases.

Rauschenberg R, Bruns J, Brütting J, Daubner D, Lohaus F, Zimmer L, Forschner A, Zips D, Hassel JC, Berking C, Kaehler KC, Utikal J, Gutzmer R, Terheyden P, Meiss F, Rafei-Shamsabadi D, Kiecker F, Debus D, Dabrowski E, Arnold A, Garzarolli M, Kuske M, Beissert S, Löck S, Linn J, Troost EGC, Meier F.

Eur J Cancer. 2019 Mar;110:11-20. doi: 10.1016/j.ejca.2018.12.023. Epub 2019 Feb 7.

41.

Sequence-dependent cross-resistance of combined radiotherapy plus BRAFV600E inhibition in melanoma.

Shannan B, Matschke J, Chauvistré H, Vogel F, Klein D, Meier F, Westphal D, Bruns J, Rauschenberg R, Utikal J, Forschner A, Berking C, Terheyden P, Dabrowski E, Gutzmer R, Rafei-Shamsabadi D, Meiss F, Heinzerling L, Zimmer L, Livingstone E, Váraljai R, Hoewner A, Horn S, Klode J, Stuschke M, Scheffler B, Marchetto A, Sannino G, Grünewald TGP, Schadendorf D, Jendrossek V, Roesch A.

Eur J Cancer. 2019 Mar;109:137-153. doi: 10.1016/j.ejca.2018.12.024. Epub 2019 Feb 2.

PMID:
30721788
42.

Serotonin 5-HT1A Receptor Biased Agonists Induce Different Cerebral Metabolic Responses: A [18F]-Fluorodesoxyglucose Positron Emission Tomography Study in Conscious and Anesthetized Rats.

Levigoureux E, Vidal B, Fieux S, Bouillot C, Emery S, Newman-Tancredi A, Zimmer L.

ACS Chem Neurosci. 2019 Jul 17;10(7):3108-3119. doi: 10.1021/acschemneuro.8b00584. Epub 2019 Jan 7.

PMID:
30576601
43.

Epidemiology of Meningitis and Encephalitis in Infants and Children in the United States, 2011-2014.

Hasbun R, Wootton SH, Rosenthal N, Balada-Llasat JM, Chung J, Duff S, Bozzette S, Zimmer L, Ginocchio CC.

Pediatr Infect Dis J. 2019 Jan;38(1):37-41. doi: 10.1097/INF.0000000000002081.

PMID:
30531527
44.

Myositis and neuromuscular side-effects induced by immune checkpoint inhibitors.

Moreira A, Loquai C, Pföhler C, Kähler KC, Knauss S, Heppt MV, Gutzmer R, Dimitriou F, Meier F, Mitzel-Rink H, Schuler G, Terheyden P, Thoms KM, Türk M, Dummer R, Zimmer L, Schröder R, Heinzerling L.

Eur J Cancer. 2019 Jan;106:12-23. doi: 10.1016/j.ejca.2018.09.033. Epub 2018 Nov 17.

PMID:
30453170
45.

Cost of managing meningitis and encephalitis among infants and children in the United States.

Balada-Llasat JM, Rosenthal N, Hasbun R, Zimmer L, Bozzette S, Duff S, Chung J, Ginocchio CC.

Diagn Microbiol Infect Dis. 2019 Apr;93(4):349-354. doi: 10.1016/j.diagmicrobio.2018.10.012. Epub 2018 Oct 27.

46.

Paclitaxel with or without trametinib or pazopanib in advanced wild-type BRAF melanoma (PACMEL): a multicentre, open-label, randomised, controlled phase II trial.

Urbonas V, Schadendorf D, Zimmer L, Danson S, Marshall E, Corrie P, Wheater M, Plummer E, Mauch C, Scudder C, Goff M, Love SB, Mohammed SB, Middleton MR.

Ann Oncol. 2019 Feb 1;30(2):317-324. doi: 10.1093/annonc/mdy500.

47.

Evaluation of [18 F]2FP3 in pigs and non-human primates.

Hansen HD, Constantinescu CC, Barret O, Herth MM, Magnussen JH, Lehel S, Dyssegaard A, Colomb J, Billard T, Zimmer L, Tamagnan G, Knudsen GM.

J Labelled Comp Radiopharm. 2019 Jan;62(1):34-42. doi: 10.1002/jlcr.3692. Epub 2018 Dec 6.

PMID:
30414212
48.

Clinical experience with combination BRAF/MEK inhibitors for melanoma with brain metastases: a real-life multicenter study.

Drago JZ, Lawrence D, Livingstone E, Zimmer L, Chen T, Giobbie-Hurder A, Amann VC, Mangana J, Siano M, Zippelius A, Dummer R, Goldinger SM, Sullivan RJ.

Melanoma Res. 2019 Feb;29(1):65-69. doi: 10.1097/CMR.0000000000000527.

PMID:
30376465
49.

Anti-PD-1/PD-L1 immunotherapy in patients with solid organ transplant, HIV or hepatitis B/C infection.

Tio M, Rai R, Ezeoke OM, McQuade JL, Zimmer L, Khoo C, Park JJ, Spain L, Turajlic S, Ardolino L, Yip D, Goldinger SM, Cohen JV, Millward M, Atkinson V, Kane AY, Ascierto PA, Garbe C, Gutzmer R, Johnson DB, Rizvi HA, Joshua AM, Hellmann MD, Long GV, Menzies AM.

Eur J Cancer. 2018 Nov;104:137-144. doi: 10.1016/j.ejca.2018.09.017. Epub 2018 Oct 20.

PMID:
30347289
50.

The efficacy of re-challenge with BRAF inhibitors after previous progression to BRAF inhibitors in melanoma: A retrospective multicenter study.

Tietze JK, Forschner A, Loquai C, Mitzel-Rink H, Zimmer L, Meiss F, Rafei-Shamsabadi D, Utikal J, Bergmann M, Meier F, Kreuzberg N, Schlaak M, Weishaupt C, Pföhler C, Ziemer M, Fluck M, Rainer J, Heppt MV, Berking C.

Oncotarget. 2018 Sep 28;9(76):34336-34346. doi: 10.18632/oncotarget.26149. eCollection 2018 Sep 28.

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