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Chronic nicotine administration restores brain region specific up-regulation of oxytocin receptor binding levels in a G72 mouse model of schizophrenia.

Zanos P, Keyworth H, Georgiou P, Kitchen I, Zimmer A, Bailey A.

Eur J Neurosci. 2018 Sep 15. doi: 10.1111/ejn.14155. [Epub ahead of print]


Cannabinoid 1 Receptor Signaling on Hippocampal GABAergic Neurons Influences Microglial Activity.

Ativie F, Komorowska JA, Beins E, Albayram Ö, Zimmer T, Zimmer A, Tejera D, Heneka M, Bilkei-Gorzo A.

Front Mol Neurosci. 2018 Aug 28;11:295. doi: 10.3389/fnmol.2018.00295. eCollection 2018.


Stilbenoid pterostilbene complexed with cyclodextrin preserves left ventricular function after myocardial infarction in rats: possible involvement of thiol proteins and modulation of phosphorylated GSK-3β.

Lacerda D, Ortiz V, Türck P, Campos-Carraro C, Zimmer A, Teixeira R, Bianchi S, de Castro AL, Schenkel PC, Belló-Klein A, Bassani VL, da Rosa Araujo AS.

Free Radic Res. 2018 Sep 11:1-12. doi: 10.1080/10715762.2018.1506115. [Epub ahead of print]


Neph2/Kirrel3 regulates sensory input, motor coordination, and home-cage activity in rodents.

Völker LA, Maar BA, Pulido Guevara BA, Bilkei-Gorzo A, Zimmer A, Brönneke H, Dafinger C, Bertsch S, Wagener JR, Schweizer H, Schermer B, Benzing T, Hoehne M.

Genes Brain Behav. 2018 Aug 22:e12516. doi: 10.1111/gbb.12516. [Epub ahead of print]


Homozygous intronic MITF mutation causes severe Waardenburg syndrome type 2A.

Rauschendorf MA, Zimmer AD, Laut A, Demmer P, Rösler B, Happle R, Sartori S, Fischer J.

Pigment Cell Melanoma Res. 2018 Aug 16. doi: 10.1111/pcmr.12733. [Epub ahead of print] No abstract available.


Cannabinoid 1 receptor signaling on GABAergic neurons influences astrocytes in the ageing brain.

Bilkei-Gorzo A, Albayram O, Ativie F, Chasan S, Zimmer T, Bach K, Zimmer A.

PLoS One. 2018 Aug 16;13(8):e0202566. doi: 10.1371/journal.pone.0202566. eCollection 2018.


The PD-L1- and IL6-mediated dampening of the IL27/STAT1 anticancer responses are prevented by α-PD-L1 or α-IL6 antibodies.

Rolvering C, Zimmer AD, Ginolhac A, Margue C, Kirchmeyer M, Servais F, Hermanns HM, Hergovits S, Nazarov PV, Nicot N, Kreis S, Haan S, Behrmann I, Haan C.

J Leukoc Biol. 2018 Jul 24. doi: 10.1002/JLB.MA1217-495R. [Epub ahead of print]


Mosaicism due to postzygotic mutations in women with focal dermal hypoplasia.

Heinz L, Bourrat E, Vabres P, Thevenon J, Hotz A, Hörer S, Küsel J, Zimmer AD, Alter S, Happle R, Fischer J.

Br J Dermatol. 2018 Jul 19. doi: 10.1111/bjd.17024. [Epub ahead of print]


Involvement of leptin signaling in the development of cannabinoid CB2 receptor-dependent mirror image pain.

Nozaki C, Nent E, Bilkei-Gorzo A, Zimmer A.

Sci Rep. 2018 Jul 17;8(1):10827. doi: 10.1038/s41598-018-28507-6.


Mutation update for CYP4F22 variants associated with autosomal recessive congenital ichthyosis.

Hotz A, Bourrat E, Küsel J, Oji V, Alter S, Hake L, Korbi M, Ott H, Hausser I, Zimmer AD, Fischer J.

Hum Mutat. 2018 Oct;39(10):1305-1313. doi: 10.1002/humu.23594. Epub 2018 Aug 7.


Role of WNT5A receptors FZD5 and RYK in prostate cancer cells.

Thiele S, Zimmer A, Göbel A, Rachner TD, Rother S, Fuessel S, Froehner M, Wirth MP, Muders MH, Baretton GB, Jakob F, Rauner M, Hofbauer LC.

Oncotarget. 2018 Jun 5;9(43):27293-27304. doi: 10.18632/oncotarget.25551. eCollection 2018 Jun 5.


GeNets: a unified web platform for network-based genomic analyses.

Li T, Kim A, Rosenbluh J, Horn H, Greenfeld L, An D, Zimmer A, Liberzon A, Bistline J, Natoli T, Li Y, Tsherniak A, Narayan R, Subramanian A, Liefeld T, Wong B, Thompson D, Calvo S, Carr S, Boehm J, Jaffe J, Mesirov J, Hacohen N, Regev A, Lage K.

Nat Methods. 2018 Jul;15(7):543-546. doi: 10.1038/s41592-018-0039-6. Epub 2018 Jun 18.


Assessing the role of the acid-sensing ion channel ASIC4b in sodium uptake by larval zebrafish.

Zimmer AM, Dymowska AK, Kumai Y, Goss GG, Perry SF, Kwong RWM.

Comp Biochem Physiol A Mol Integr Physiol. 2018 Jun 15;226:1-10. doi: 10.1016/j.cbpa.2018.06.012. [Epub ahead of print]


Cannabinoid Receptor 2-Deficiency Ameliorates Disease Symptoms in a Mouse Model with Alzheimer's Disease-Like Pathology.

Schmöle AC, Lundt R, Toporowski G, Hansen JN, Beins E, Halle A, Zimmer A.

J Alzheimers Dis. 2018;64(2):379-392. doi: 10.3233/JAD-180230.


Elevated levels of 2-arachidonoylglycerol promote atherogenesis in ApoE-/- mice.

Jehle J, Schöne B, Bagheri S, Avraamidou E, Danisch M, Frank I, Pfeifer P, Bindila L, Lutz B, Lütjohann D, Zimmer A, Nickenig G.

PLoS One. 2018 May 29;13(5):e0197751. doi: 10.1371/journal.pone.0197751. eCollection 2018.


Limited fibrosis accompanies triple-negative breast cancer metastasis in multiple model systems and is not a preventive target.

Brooks D, Zimmer A, Wakefield L, Lyle LT, Difilippantonio S, Tucci FC, Illiano S, Annunziata CM, Steeg PS.

Oncotarget. 2018 May 4;9(34):23462-23481. doi: 10.18632/oncotarget.25231. eCollection 2018 May 4.


The PERIOPTER syndrome (periorificial and ptychotropic erythrokeratoderma): a new Mendelian disorder of cornification.

Bursztejn AC, Happle R, Charbit L, Küsel J, Leclerc-Mercier S, Hadj-Rabia S, Fraitag S, Zimmer A, Fischer J.

J Eur Acad Dermatol Venereol. 2018 May 25. doi: 10.1111/jdv.15089. [Epub ahead of print] No abstract available.


Management of placenta percreta with temporary balloon occlusion of the internal iliac arteries.

Rosner-Tenerowicz A, Pomorski M, Fuchs T, Śliwa J, Pilecka K, Zimmer A, Zimmer M.

Eur J Obstet Gynecol Reprod Biol. 2018 Jul;226:71-72. doi: 10.1016/j.ejogrb.2018.05.014. Epub 2018 May 14. No abstract available.


Referred cramping phantom hand pain elicited in the face and eliminated by peripheral nerve block.

Dietrich C, Nehrdich S, Zimmer A, Ritter A, Hofmann GO, Miltner WHR, Weiss T.

Exp Brain Res. 2018 Jun;236(6):1815-1824. doi: 10.1007/s00221-018-5262-y. Epub 2018 Apr 17.


A machine learning model to determine the accuracy of variant calls in capture-based next generation sequencing.

van den Akker J, Mishne G, Zimmer AD, Zhou AY.

BMC Genomics. 2018 Apr 17;19(1):263. doi: 10.1186/s12864-018-4659-0.


Update on PARP Inhibitors in Breast Cancer.

Zimmer AS, Gillard M, Lipkowitz S, Lee JM.

Curr Treat Options Oncol. 2018 Apr 11;19(5):21. doi: 10.1007/s11864-018-0540-2. Review.


SERCA plays a crucial role in the toxicity of a betulinic acid derivative with potential antimalarial activity.

Diedrich D, Wildner AC, Silveira TF, Silva GNS, Santos FD, da Silva EF, do Canto VP, Visioli F, Gosmann G, Bergold AM, Zimmer AR, Netz PA, Gnoatto SCB.

Chem Biol Interact. 2018 May 1;287:70-77. doi: 10.1016/j.cbi.2018.03.014. Epub 2018 Mar 28.


The loss of SMG1 causes defects in quality control pathways in Physcomitrella patens.

Lloyd JPB, Lang D, Zimmer AD, Causier B, Reski R, Davies B.

Nucleic Acids Res. 2018 Jun 20;46(11):5822-5836. doi: 10.1093/nar/gky225.


Influence of cell type and cell culture media on the propagation of foot-and-mouth disease virus with regard to vaccine quality.

Dill V, Hoffmann B, Zimmer A, Beer M, Eschbaumer M.

Virol J. 2018 Mar 16;15(1):46. doi: 10.1186/s12985-018-0956-0.


Exercise training versus T3 and T4 hormones treatment: The differential benefits of thyroid hormones on the parasympathetic drive of infarcted rats.

Teixeira RB, Zimmer A, de Castro AL, Carraro CC, Casali KR, Dias IGM, Godoy AEG, Litvin IE, Belló-Klein A, da Rosa Araujo AS.

Life Sci. 2018 Mar 1;196:93-101. doi: 10.1016/j.lfs.2018.01.018. Epub 2018 Feb 3.


Prexasertib, a cell cycle checkpoint kinase 1 and 2 inhibitor, in BRCA wild-type recurrent high-grade serous ovarian cancer: a first-in-class proof-of-concept phase 2 study.

Lee JM, Nair J, Zimmer A, Lipkowitz S, Annunziata CM, Merino MJ, Swisher EM, Harrell MI, Trepel JB, Lee MJ, Bagheri MH, Botesteanu DA, Steinberg SM, Minasian L, Ekwede I, Kohn EC.

Lancet Oncol. 2018 Feb;19(2):207-215. doi: 10.1016/S1470-2045(18)30009-3. Epub 2018 Jan 18.


Analysis of breast cancer in young women in the Department of Defense (DOD) database.

Zimmer AS, Zhu K, Steeg PS, Wu A, Gatti-Mays ME, Soltani S, Perkins JG, Shao S, Brown D, Georg M, Hu H, Shriver CD, Lipkowitz S.

Breast Cancer Res Treat. 2018 Apr;168(2):501-511. doi: 10.1007/s10549-017-4615-8. Epub 2017 Dec 15.


The Position of Targeted Next-generation Sequencing in Epidermolysis Bullosa Diagnosis.

Has C, Küsel J, Reimer A, Hoffmann J, Schauer F, Zimmer A, Fischer J.

Acta Derm Venereol. 2018 Apr 16;98(4):437-440. doi: 10.2340/00015555-2863.


The Physcomitrella patens chromosome-scale assembly reveals moss genome structure and evolution.

Lang D, Ullrich KK, Murat F, Fuchs J, Jenkins J, Haas FB, Piednoel M, Gundlach H, Van Bel M, Meyberg R, Vives C, Morata J, Symeonidi A, Hiss M, Muchero W, Kamisugi Y, Saleh O, Blanc G, Decker EL, van Gessel N, Grimwood J, Hayes RD, Graham SW, Gunter LE, McDaniel SF, Hoernstein SNW, Larsson A, Li FW, Perroud PF, Phillips J, Ranjan P, Rokshar DS, Rothfels CJ, Schneider L, Shu S, Stevenson DW, Thümmler F, Tillich M, Villarreal Aguilar JC, Widiez T, Wong GK, Wymore A, Zhang Y, Zimmer AD, Quatrano RS, Mayer KFX, Goodstein D, Casacuberta JM, Vandepoele K, Reski R, Cuming AC, Tuskan GA, Maumus F, Salse J, Schmutz J, Rensing SA.

Plant J. 2018 Feb;93(3):515-533. doi: 10.1111/tpj.13801.


Performance indicators for carrier-based DPIs: Carrier surface properties for capsule filling and API properties for in vitro aerosolisation.

Faulhammer E, Zellnitz S, Wutscher T, Stranzinger S, Zimmer A, Paudel A.

Int J Pharm. 2018 Jan 30;536(1):326-335. doi: 10.1016/j.ijpharm.2017.12.004. Epub 2017 Dec 5.


Adherence to fingolimod in multiple sclerosis: an investigator-initiated, prospective, observational, single-center cohort study.

Zimmer A, Coslovsky M, Abraham I, Décard BF.

Patient Prefer Adherence. 2017 Oct 20;11:1815-1830. doi: 10.2147/PPA.S140293. eCollection 2017.


Dynamic Proteomics of Herpes Simplex Virus Infection.

Drayman N, Karin O, Mayo A, Danon T, Shapira L, Rafael D, Zimmer A, Bren A, Kobiler O, Alon U.

MBio. 2017 Nov 7;8(6). pii: e01612-17. doi: 10.1128/mBio.01612-17.


Ammonia and urea handling by early life stages of fishes.

Zimmer AM, Wright PA, Wood CM.

J Exp Biol. 2017 Nov 1;220(Pt 21):3843-3855. doi: 10.1242/jeb.140210. Review.


Prediction of drug cocktail effects when the number of measurements is limited.

Zimmer A, Tendler A, Katzir I, Mayo A, Alon U.

PLoS Biol. 2017 Oct 26;15(10):e2002518. doi: 10.1371/journal.pbio.2002518. eCollection 2017 Oct.


Solvent Vapor Annealing of Amorphous Carbamazepine Films for Fast Polymorph Screening and Dissolution Alteration.

Schrode B, Bodak B, Riegler H, Zimmer A, Christian P, Werzer O.

ACS Omega. 2017 Sep 30;2(9):5582-5590. doi: 10.1021/acsomega.7b00783. Epub 2017 Sep 7.


Understanding gene functions and disease mechanisms: Phenotyping pipelines in the German Mouse Clinic.

Fuchs H, Aguilar-Pimentel JA, Amarie OV, Becker L, Calzada-Wack J, Cho YL, Garrett L, Hölter SM, Irmler M, Kistler M, Kraiger M, Mayer-Kuckuk P, Moreth K, Rathkolb B, Rozman J, da Silva Buttkus P, Treise I, Zimprich A, Gampe K, Hutterer C, Stöger C, Leuchtenberger S, Maier H, Miller M, Scheideler A, Wu M, Beckers J, Bekeredjian R, Brielmeier M, Busch DH, Klingenspor M, Klopstock T, Ollert M, Schmidt-Weber C, Stöger T, Wolf E, Wurst W, Yildirim AÖ, Zimmer A, Gailus-Durner V, Hrabě de Angelis M.

Behav Brain Res. 2018 Oct 15;352:187-196. doi: 10.1016/j.bbr.2017.09.048. Epub 2017 Sep 29. Review.


Quinalizarin inhibits adipogenesis through down-regulation of transcription factors and microRNA modulation.

Schwind L, Nalbach L, Zimmer AD, Kostelnik KB, Menegatti J, Grässer F, Götz C, Montenarh M.

Biochim Biophys Acta Gen Subj. 2017 Dec;1861(12):3272-3281. doi: 10.1016/j.bbagen.2017.09.018. Epub 2017 Sep 28.


People, planet and profit: Unintended consequences of legacy building materials.

Zimmer AT, Ha H.

J Environ Manage. 2017 Dec 15;204(Pt 1):472-485. doi: 10.1016/j.jenvman.2017.09.026. Review.


Long-term T3 and T4 treatment as an alternative to aerobic exercise training in improving cardiac function post-myocardial infarction.

Teixeira RB, Zimmer A, de Castro AL, de Lima-Seolin BG, Türck P, Siqueira R, Belló-Klein A, Singal PK, da Rosa Araujo AS.

Biomed Pharmacother. 2017 Nov;95:965-973. doi: 10.1016/j.biopha.2017.09.021. Epub 2017 Sep 11.


Combined effect of the Saccharomyces cerevisiae lag phase and the non-Saccharomyces consortium to enhance wine fruitiness and complexity.

Albertin W, Zimmer A, Miot-Sertier C, Bernard M, Coulon J, Moine V, Colonna-Ceccaldi B, Bely M, Marullo P, Masneuf-Pomarede I.

Appl Microbiol Biotechnol. 2017 Oct;101(20):7603-7620. doi: 10.1007/s00253-017-8492-1. Epub 2017 Sep 14.


Identification of mutations in SDR9C7 in six families with autosomal recessive congenital ichthyosis.

Hotz A, Fagerberg C, Vahlquist A, Bygum A, Törmä H, Rauschendorf MA, Zhang H, Heinz L, Bourrat E, Hausser I, Vestergaard V, Dragomir A, Zimmer AD, Fischer J.

Br J Dermatol. 2018 Mar;178(3):e207-e209. doi: 10.1111/bjd.15994. Epub 2018 Jan 21. No abstract available.


Developmental programming of somatic growth, behavior and endocannabinoid metabolism by variation of early postnatal nutrition in a cross-fostering mouse model.

Schreiner F, Ackermann M, Michalik M, Hucklenbruch-Rother E, Bilkei-Gorzo A, Racz I, Bindila L, Lutz B, Dötsch J, Zimmer A, Woelfle J.

PLoS One. 2017 Aug 31;12(8):e0182754. doi: 10.1371/journal.pone.0182754. eCollection 2017.


Designing optimal formulations for hot-melt coating.

Lopes DG, Salar-Behzadi S, Zimmer A.

Int J Pharm. 2017 Nov 30;533(2):357-363. doi: 10.1016/j.ijpharm.2017.08.086. Epub 2017 Aug 24.


Adaption of FMDV Asia-1 to Suspension Culture: Cell Resistance Is Overcome by Virus Capsid Alterations.

Dill V, Hoffmann B, Zimmer A, Beer M, Eschbaumer M.

Viruses. 2017 Aug 18;9(8). pii: E231. doi: 10.3390/v9080231.


Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in mice.

Xie K, Neff F, Markert A, Rozman J, Aguilar-Pimentel JA, Amarie OV, Becker L, Brommage R, Garrett L, Henzel KS, Hölter SM, Janik D, Lehmann I, Moreth K, Pearson BL, Racz I, Rathkolb B, Ryan DP, Schröder S, Treise I, Bekeredjian R, Busch DH, Graw J, Ehninger G, Klingenspor M, Klopstock T, Ollert M, Sandholzer M, Schmidt-Weber C, Weiergräber M, Wolf E, Wurst W, Zimmer A, Gailus-Durner V, Fuchs H, Hrabě de Angelis M, Ehninger D.

Nat Commun. 2017 Jul 24;8(1):155. doi: 10.1038/s41467-017-00178-3.


Fgf9 Y162C Mutation Alters Information Processing and Social Memory in Mice.

Garrett L, Becker L, Rozman J, Puk O, Stoeger T, Yildirim AÖ, Bohla A, Eickelberg O, Hans W, Prehn C, Adamski J, Klopstock T, Rácz I, Zimmer A, Klingenspor M, Fuchs H, Gailus-Durner V, Wurst W, Hrabě de Angelis M, Graw J, Hölter SM.

Mol Neurobiol. 2018 Jun;55(6):4580-4595. doi: 10.1007/s12035-017-0659-3. Epub 2017 Jul 10.


Meis1: effects on motor phenotypes and the sensorimotor system in mice.

Salminen AV, Garrett L, Schormair B, Rozman J, Giesert F, Niedermeier KM, Becker L, Rathkolb B, Rácz I; German Mouse Clinic Consortium, Klingenspor M, Klopstock T, Wolf E, Zimmer A, Gailus-Durner V, Torres M, Fuchs H, Hrabě de Angelis M, Wurst W, Hölter SM, Winkelmann J.

Dis Model Mech. 2017 Aug 1;10(8):981-991. doi: 10.1242/dmm.030080. Epub 2017 Jun 23.


Chemokine CCL17 is expressed by dendritic cells in the CNS during experimental autoimmune encephalomyelitis and promotes pathogenesis of disease.

Ruland C, Renken H, Kuzmanov I, Fattahi Mehr A, Schwarte K, Cerina M, Herrmann A, Otte DM, Zimmer A, Schwab N, Meuth SG, Arolt V, Klotz L, Förster I, Scheu S, Alferink J.

Brain Behav Immun. 2017 Nov;66:382-393. doi: 10.1016/j.bbi.2017.06.010. Epub 2017 Jun 19.


Tick, Diseases, Babesiosis.

Zimmer AJ, Simonsen KA.

StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2018 Jan-.
2017 Feb 7.


ROS production induced by BRAF inhibitor treatment rewires metabolic processes affecting cell growth of melanoma cells.

Cesi G, Walbrecq G, Zimmer A, Kreis S, Haan C.

Mol Cancer. 2017 Jun 8;16(1):102. doi: 10.1186/s12943-017-0667-y.

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