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Items: 8


Unique structural features in an Nramp metal transporter impart substrate-specific proton cotransport and a kinetic bias to favor import.

Bozzi AT, Bane LB, Zimanyi CM, Gaudet R.

J Gen Physiol. 2019 Oct 16. pii: jgp.201912428. doi: 10.1085/jgp.201912428. [Epub ahead of print]


Structures in multiple conformations reveal distinct transition metal and proton pathways in an Nramp transporter.

Bozzi AT, Zimanyi CM, Nicoludis JM, Lee BK, Zhang CH, Gaudet R.

Elife. 2019 Feb 4;8. pii: e41124. doi: 10.7554/eLife.41124.


A widespread family of serine/threonine protein phosphatases shares a common regulatory switch with proteasomal proteases.

Bradshaw N, Levdikov VM, Zimanyi CM, Gaudet R, Wilkinson AJ, Losick R.

Elife. 2017 May 20;6. pii: e26111. doi: 10.7554/eLife.26111.


Novel mutations highlight the key role of the ankyrin repeat domain in TRPV4-mediated neuropathy.

Sullivan JM, Zimanyi CM, Aisenberg W, Bears B, Chen DH, Day JW, Bird TD, Siskind CE, Gaudet R, Sumner CJ.

Neurol Genet. 2015 Oct 22;1(4):e29. doi: 10.1212/NXG.0000000000000029. eCollection 2015 Dec.


Molecular basis for allosteric specificity regulation in class Ia ribonucleotide reductase from Escherichia coli.

Zimanyi CM, Chen PY, Kang G, Funk MA, Drennan CL.

Elife. 2016 Jan 12;5:e07141. doi: 10.7554/eLife.07141.


Tangled up in knots: structures of inactivated forms of E. coli class Ia ribonucleotide reductase.

Zimanyi CM, Ando N, Brignole EJ, Asturias FJ, Stubbe J, Drennan CL.

Structure. 2012 Aug 8;20(8):1374-83. doi: 10.1016/j.str.2012.05.009. Epub 2012 Jun 21.


The prototypic class Ia ribonucleotide reductase from Escherichia coli: still surprising after all these years.

Brignole EJ, Ando N, Zimanyi CM, Drennan CL.

Biochem Soc Trans. 2012 Jun 1;40(3):523-30. doi: 10.1042/BST20120081. Review.


Structural interconversions modulate activity of Escherichia coli ribonucleotide reductase.

Ando N, Brignole EJ, Zimanyi CM, Funk MA, Yokoyama K, Asturias FJ, Stubbe J, Drennan CL.

Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21046-51. doi: 10.1073/pnas.1112715108. Epub 2011 Dec 12.

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