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Recent Development of Visceral Leishmaniasis Treatments: Successes, Pitfalls, and Perspectives.

Alves F, Bilbe G, Blesson S, Goyal V, Monnerat S, Mowbray C, Muthoni Ouattara G, Pécoul B, Rijal S, Rode J, Solomos A, Strub-Wourgaft N, Wasunna M, Wells S, Zijlstra EE, Arana B, Alvar J.

Clin Microbiol Rev. 2018 Aug 29;31(4). pii: e00048-18. doi: 10.1128/CMR.00048-18. Print 2018 Oct. Review.


Safety and Effectiveness of Short-Course AmBisome in the Treatment of Post-Kala-Azar Dermal Leishmaniasis: A Prospective Cohort Study in Bangladesh.

den Boer M, Das AK, Akhter F, Burza S, Ramesh V, Ahmed BN, Zijlstra EE, Ritmeijer K.

Clin Infect Dis. 2018 Aug 16;67(5):667-675. doi: 10.1093/cid/ciy172.


Para-kala-azar dermal leishmaniasis in a patient in Brazil: a case report.

Lindoso JAL, Moreira CHV, Celeste BJ, Oyafuso LKM, Folegatti PM, Zijlstra EE.

Rev Soc Bras Med Trop. 2018 Jan-Feb;51(1):105-107. doi: 10.1590/0037-8682-0487-2016. Erratum in: Rev Soc Bras Med Trop. 2018 May-Jun;51(3):411.


Post-kala-azar dermal leishmaniasis in the Indian subcontinent: A threat to the South-East Asia Region Kala-azar Elimination Programme.

Zijlstra EE, Alves F, Rijal S, Arana B, Alvar J.

PLoS Negl Trop Dis. 2017 Nov 16;11(11):e0005877. doi: 10.1371/journal.pntd.0005877. eCollection 2017 Nov. Review.


A trial of a 7-valent pneumococcal conjugate vaccine in HIV-infected adults.

French N, Gordon SB, Mwalukomo T, White SA, Mwafulirwa G, Longwe H, Mwaiponya M, Zijlstra EE, Molyneux ME, Gilks CF.

Malawi Med J. 2016 Sep;28(3):115-122.


The immunology of post-kala-azar dermal leishmaniasis (PKDL).

Zijlstra EE.

Parasit Vectors. 2016 Aug 23;9:464. doi: 10.1186/s13071-016-1721-0. Review.


Visceral leishmaniasis: a forgotten epidemic.

Zijlstra EE.

Arch Dis Child. 2016 Jun;101(6):561-567. doi: 10.1136/archdischild-2015-309302. Epub 2016 Feb 19.


Mycetoma: A Long Journey from Neglect.

Zijlstra EE, van de Sande WW, Fahal AH.

PLoS Negl Trop Dis. 2016 Jan 21;10(1):e0004244. doi: 10.1371/journal.pntd.0004244. eCollection 2016 Jan. No abstract available.


Mycetoma: a unique neglected tropical disease.

Zijlstra EE, van de Sande WWJ, Welsh O, Mahgoub ES, Goodfellow M, Fahal AH.

Lancet Infect Dis. 2016 Jan;16(1):100-112. doi: 10.1016/S1473-3099(15)00359-X. Review.


Pharmacokinetics of Antituberculosis Drugs in HIV-Positive and HIV-Negative Adults in Malawi.

van Oosterhout JJ, Dzinjalamala FK, Dimba A, Waterhouse D, Davies G, Zijlstra EE, Molyneux ME, Molyneux EM, Ward S.

Antimicrob Agents Chemother. 2015 Oct;59(10):6175-80. doi: 10.1128/AAC.01193-15. Epub 2015 Jul 27.


PKDL and other dermal lesions in HIV co-infected patients with Leishmaniasis: review of clinical presentation in relation to immune responses.

Zijlstra EE.

PLoS Negl Trop Dis. 2014 Nov 20;8(11):e3258. doi: 10.1371/journal.pntd.0003258. eCollection 2014. Review.


A new model for management of mycetoma in the Sudan.

Fahal A, Mahgoub el S, El Hassan AM, Abdel-Rahman ME, Alshambaty Y, Hashim A, Hago A, Zijlstra EE.

PLoS Negl Trop Dis. 2014 Oct 30;8(10):e3271. doi: 10.1371/journal.pntd.0003271. eCollection 2014 Oct.


Visceral leishmaniasis and HIV coinfection: time for concerted action.

van Griensven J, Zijlstra EE, Hailu A.

PLoS Negl Trop Dis. 2014 Aug 28;8(8):e3023. doi: 10.1371/journal.pntd.0003023. eCollection 2014 Aug. No abstract available.


A screen-and-treat strategy targeting visceral leishmaniasis in HIV-infected individuals in endemic East African countries: the way forward?

van Griensven J, Diro E, Lopez-Velez R, Ritmeijer K, Boelaert M, Zijlstra EE, Hailu A, Lynen L.

PLoS Negl Trop Dis. 2014 Aug 7;8(8):e3011. doi: 10.1371/journal.pntd.0003011. eCollection 2014 Aug. Review.


Merits and pitfalls of currently used diagnostic tools in mycetoma.

van de Sande WW, Fahal AH, Goodfellow M, Mahgoub el S, Welsh O, Zijlstra EE.

PLoS Negl Trop Dis. 2014 Jul 3;8(7):e2918. doi: 10.1371/journal.pntd.0002918. eCollection 2014 Jul. Review.


Madurella mycetomatis is highly susceptible to ravuconazole.

Ahmed SA, Kloezen W, Duncanson F, Zijlstra EE, de Hoog GS, Fahal AH, van de Sande WW.

PLoS Negl Trop Dis. 2014 Jun 19;8(6):e2942. doi: 10.1371/journal.pntd.0002942. eCollection 2014 Jun.


Novel cyclovirus in human cerebrospinal fluid, Malawi, 2010-2011.

Smits SL, Zijlstra EE, van Hellemond JJ, Schapendonk CM, Bodewes R, Schürch AC, Haagmans BL, Osterhaus AD.

Emerg Infect Dis. 2013;19(9). doi: 10.3201/eid1909.130404.


High mortality amongst adolescents and adults with bacterial meningitis in sub-Saharan Africa: an analysis of 715 cases from Malawi.

Wall EC, Cartwright K, Scarborough M, Ajdukiewicz KM, Goodson P, Mwambene J, Zijlstra EE, Gordon SB, French N, Faragher B, Heyderman RS, Lalloo DG.

PLoS One. 2013 Jul 19;8(7):e69783. doi: 10.1371/journal.pone.0069783. Print 2013.


Report of the Post Kala-azar Dermal Leishmaniasis (PKDL) Consortium Meeting, New Delhi, India, 27-29 June 2012.

Desjeux P, Ghosh RS, Dhalaria P, Strub-Wourgaft N, Zijlstra EE.

Parasit Vectors. 2013 Jul 2;6:196. doi: 10.1186/1756-3305-6-196.


The alveolar microenvironment of patients infected with human immunodeficiency virus does not modify alveolar macrophage interactions with Streptococcus pneumoniae.

Gordon SB, Jagoe RT, Jarman ER, North JC, Pridmore A, Musaya J, French N, Zijlstra EE, Molyneux ME, Read RC.

Clin Vaccine Immunol. 2013 Jun;20(6):882-91. doi: 10.1128/CVI.00582-12. Epub 2013 Apr 10.


Filicide and suicide in a family by paraphenylene diamine poisoning: a mother who committed suicide and poisoned her four children of which one died.

Abdelraheem MB, Elbushra M, Ali el-T, Ellidir RA, Bushara AI, Abdelraheem WB, Zijlstra EE.

Toxicol Ind Health. 2014 Sep;30(8):679-82. doi: 10.1177/0748233712448118. Epub 2012 Dec 6.


Analytical investigations of toxic p-phenylenediamine (PPD) levels in clinical urine samples with special focus on MALDI-MS/MS.

Hooff GP, van Huizen NA, Meesters RJ, Zijlstra EE, Abdelraheem M, Abdelraheem W, Hamdouk M, Lindemans J, Luider TM.

PLoS One. 2011;6(8):e22191. doi: 10.1371/journal.pone.0022191. Epub 2011 Aug 4.


Etiology of suspected pneumonia in adults admitted to a high-dependency unit in Blantyre, Malawi.

Hartung TK, Chimbayo D, van Oosterhout JJ, Chikaonda T, van Doornum GJ, Claas EC, Melchers WJ, Molyneux ME, Zijlstra EE.

Am J Trop Med Hyg. 2011 Jul;85(1):105-12. doi: 10.4269/ajtmh.2011.10-0640. Erratum in: Am J Trop Med Hyg. 2011 Sep;85(3):582.


Blindness following visceral leishmaniasis: a neglected post-kala-azar complication.

Khalil EA, Musa AM, Younis BM, Elfaki ME, Zijlstra EE, Elhassan AM.

Trop Doct. 2011 Jul;41(3):139-40. doi: 10.1258/td.2011.110058. Epub 2011 Jun 15.


Prevalence of diabetic retinopathy, cataract and visual impairment in patients with diabetes in sub-Saharan Africa.

Glover SJ, Burgess PI, Cohen DB, Harding SP, Hofland HW, Zijlstra EE, Allain TJ.

Br J Ophthalmol. 2012 Feb;96(2):156-61. doi: 10.1136/bjo.2010.196071. Epub 2011 Apr 21.


Glycerol adjuvant therapy in adults with bacterial meningitis in a high HIV seroprevalence setting in Malawi: a double-blind, randomised controlled trial.

Ajdukiewicz KM, Cartwright KE, Scarborough M, Mwambene JB, Goodson P, Molyneux ME, Zijlstra EE, French N, Whitty CJ, Lalloo DG.

Lancet Infect Dis. 2011 Apr;11(4):293-300. doi: 10.1016/S1473-3099(10)70317-0. Epub 2011 Feb 18.


The safety and efficacy of itraconazole for the treatment of patients with eumycetoma due to Madurella mycetomatis.

Fahal AH, Rahman IA, El-Hassan AM, Rahman ME, Zijlstra EE.

Trans R Soc Trop Med Hyg. 2011 Mar;105(3):127-32. doi: 10.1016/j.trstmh.2010.11.008. Epub 2011 Jan 17.


A survey of the management, control, and complications of diabetes mellitus in patients attending a diabetes clinic in Blantyre, Malawi, an area of high HIV prevalence.

Cohen DB, Allain TJ, Glover S, Chimbayo D, Dzamalala H, Hofland HW, Banda NP, Zijlstra EE.

Am J Trop Med Hyg. 2010 Sep;83(3):575-81. doi: 10.4269/ajtmh.2010.10-0104.


Diagnosis of cryptococcal and tuberculous meningitis in a resource-limited African setting.

Cohen DB, Zijlstra EE, Mukaka M, Reiss M, Kamphambale S, Scholing M, Waitt PI, Neuhann F.

Trop Med Int Health. 2010 Aug;15(8):910-7. doi: 10.1111/j.1365-3156.2010.02565.x. Epub 2010 Jun 21.


Favourable one-year ART outcomes in adult Malawians with hepatitis B and C co-infection.

Moore E, Beadsworth MB, Chaponda M, Mhango B, Faragher B, Njala J, Hofland HW, Davies J, Hart IJ, Beeching NJ, Zijlstra EE, van Oosterhout JJ.

J Infect. 2010 Jul;61(2):155-63. doi: 10.1016/j.jinf.2010.04.009. Epub 2010 May 12.


The benefit of supplementary feeding for wasted Malawian adults initiating ART.

van Oosterhout JJ, Ndekha M, Moore E, Kumwenda JJ, Zijlstra EE, Manary M.

AIDS Care. 2010 Jun;22(6):737-42. doi: 10.1080/09540120903373581.


Dysregulated humoral immunity to nontyphoidal Salmonella in HIV-infected African adults.

MacLennan CA, Gilchrist JJ, Gordon MA, Cunningham AF, Cobbold M, Goodall M, Kingsley RA, van Oosterhout JJ, Msefula CL, Mandala WL, Leyton DL, Marshall JL, Gondwe EN, Bobat S, López-Macías C, Doffinger R, Henderson IR, Zijlstra EE, Dougan G, Drayson MT, MacLennan IC, Molyneux ME.

Science. 2010 Apr 23;328(5977):508-12. doi: 10.1126/science.1180346.


A trial of a 7-valent pneumococcal conjugate vaccine in HIV-infected adults.

French N, Gordon SB, Mwalukomo T, White SA, Mwafulirwa G, Longwe H, Mwaiponya M, Zijlstra EE, Molyneux ME, Gilks CF.

N Engl J Med. 2010 Mar 4;362(9):812-22. doi: 10.1056/NEJMoa0903029.


Invasive non-typhoid salmonellae establish systemic intracellular infection in HIV-infected adults: an emerging disease pathogenesis.

Gordon MA, Kankwatira AM, Mwafulirwa G, Walsh AL, Hopkins MJ, Parry CM, Faragher EB, Zijlstra EE, Heyderman RS, Molyneux ME.

Clin Infect Dis. 2010 Apr 1;50(7):953-62. doi: 10.1086/651080.


Reliability of rapid testing for hepatitis B in a region of high HIV endemicity.

Davies J, van Oosterhout JJ, Nyirenda M, Bowden J, Moore E, Hart IJ, Zijlstra EE, Chaponda M, Faragher B, Beeching NJ, Beadsworth MB.

Trans R Soc Trop Med Hyg. 2010 Feb;104(2):162-4. doi: 10.1016/j.trstmh.2009.10.010.


[An HIV positive man with skin ulcers in the face. Cryptococcus].

Steketee WH, Zijlstra EE.

Ned Tijdschr Geneeskd. 2009 Apr 4;153(14):677. Dutch. No abstract available.


Effect of recurrent invasive pneumococcal disease on serum anti-pneumolysin IgG titres in HIV infected adults.

Etuwewe OM, Swann N, Hollingshead S, Tolmie H, Zijlstra EE, Faragher B, French N, Gordon SB.

Vaccine. 2009 Jun 12;27(29):3881-4. doi: 10.1016/j.vaccine.2009.04.026. Epub 2009 May 3.


Domestic smoke exposure is associated with alveolar macrophage particulate load.

Fullerton DG, Jere K, Jambo K, Kulkarni NS, Zijlstra EE, Grigg J, French N, Molyneux ME, Gordon SB.

Trop Med Int Health. 2009 Mar;14(3):349-54. doi: 10.1111/j.1365-3156.2009.02230.x.


Simple measures are as effective as invasive techniques in the diagnosis of pulmonary tuberculosis in Malawi.

Bell DJ, Dacombe R, Graham SM, Hicks A, Cohen D, Chikaonda T, French N, Molyneux ME, Zijlstra EE, Squire SB, Gordon SB.

Int J Tuberc Lung Dis. 2009 Jan;13(1):99-104.


Blood culture collection technique and pneumococcal surveillance in Malawi during the four year period 2003-2006: an observational study.

Mtunthama N, Gordon SB, Kusimbwe T, Zijlstra EE, Molyneux ME, French N.

BMC Infect Dis. 2008 Oct 14;8:137. doi: 10.1186/1471-2334-8-137.


Inhaled delivery of 23-valent pneumococcal polysaccharide vaccine does not result in enhanced pulmonary mucosal immunoglobulin responses.

Gordon SB, Malamba R, Mthunthama N, Jarman ER, Jambo K, Jere K, Zijlstra EE, Molyneux ME, Dennis J, French N.

Vaccine. 2008 Oct 3;26(42):5400-6. doi: 10.1016/j.vaccine.2008.07.082. Epub 2008 Aug 15.


Prevalence of infection with hepatitis B and C virus and coinfection with HIV in medical inpatients in Malawi.

Nyirenda M, Beadsworth MB, Stephany P, Hart CA, Hart IJ, Munthali C, Beeching NJ, Zijlstra EE.

J Infect. 2008 Jul;57(1):72-7. doi: 10.1016/j.jinf.2008.05.004. Epub 2008 Jun 13.


[Emigration of physicians from Africa: focus on Malawi].

Zijlstra EE.

Ned Tijdschr Geneeskd. 2008 Apr 26;152(17):1015-9. Dutch.


Epidemics of invasive Salmonella enterica serovar enteritidis and S. enterica Serovar typhimurium infection associated with multidrug resistance among adults and children in Malawi.

Gordon MA, Graham SM, Walsh AL, Wilson L, Phiri A, Molyneux E, Zijlstra EE, Heyderman RS, Hart CA, Molyneux ME.

Clin Infect Dis. 2008 Apr 1;46(7):963-9. doi: 10.1086/529146.


Malawians permit research bronchoscopy due to perceived need for healthcare.

Mtunthama N, Malamba R, French N, Molyneux ME, Zijlstra EE, Gordon SB.

J Med Ethics. 2008 Apr;34(4):303-7. doi: 10.1136/jme.2007.020461.


Hypoadrenalism is not associated with early mortality during tuberculosis treatment in Malawi.

Beadsworth MB, van Oosterhout JJ, Diver MJ, Faragher EB, Shenkin A, Mwandumba HC, Khoo S, O'Dempsey T, Squire SB, Zijlstra EE.

Int J Tuberc Lung Dis. 2008 Mar;12(3):314-8.


Sulfadoxine-pyrimethamine-based combinations for malaria: a randomised blinded trial to compare efficacy, safety and selection of resistance in Malawi.

Bell DJ, Nyirongo SK, Mukaka M, Zijlstra EE, Plowe CV, Molyneux ME, Ward SA, Winstanley PA.

PLoS One. 2008 Feb 13;3(2):e1578. doi: 10.1371/journal.pone.0001578.


Corticosteroids for bacterial meningitis in adults in sub-Saharan Africa.

Scarborough M, Gordon SB, Whitty CJ, French N, Njalale Y, Chitani A, Peto TE, Lalloo DG, Zijlstra EE.

N Engl J Med. 2007 Dec 13;357(24):2441-50.


Primary macrophages from HIV-infected adults show dysregulated cytokine responses to Salmonella, but normal internalization and killing.

Gordon MA, Gordon SB, Musaya L, Zijlstra EE, Molyneux ME, Read RC.

AIDS. 2007 Nov 30;21(18):2399-408.


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