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Items: 15


An apical MRCK-driven morphogenetic pathway controls epithelial polarity.

Zihni C, Vlassaks E, Terry S, Carlton J, Leung TKC, Olson M, Pichaud F, Balda MS, Matter K.

Nat Cell Biol. 2017 Sep;19(9):1049-1060. doi: 10.1038/ncb3592. Epub 2017 Aug 21.


Biallelic Mutation of ARHGEF18, Involved in the Determination of Epithelial Apicobasal Polarity, Causes Adult-Onset Retinal Degeneration.

Arno G, Carss KJ, Hull S, Zihni C, Robson AG, Fiorentino A; UK Inherited Retinal Disease Consortium, Hardcastle AJ, Holder GE, Cheetham ME, Plagnol V; NIHR Bioresource - Rare Diseases Consortium, Moore AT, Raymond FL, Matter K, Balda MS, Webster AR.

Am J Hum Genet. 2017 Feb 2;100(2):334-342. doi: 10.1016/j.ajhg.2016.12.014. Epub 2017 Jan 26.


Tight junctions: from simple barriers to multifunctional molecular gates.

Zihni C, Mills C, Matter K, Balda MS.

Nat Rev Mol Cell Biol. 2016 Sep;17(9):564-80. doi: 10.1038/nrm.2016.80. Epub 2016 Jun 29. Review.


RhoGTPase signalling at epithelial tight junctions: Bridging the GAP between polarity and cancer.

Zihni C, Terry SJ.

Int J Biochem Cell Biol. 2015 Jul;64:120-5. doi: 10.1016/j.biocel.2015.02.020. Epub 2015 Mar 7. Review.


Signalling at tight junctions during epithelial differentiation and microbial pathogenesis.

Zihni C, Balda MS, Matter K.

J Cell Sci. 2014 Aug 15;127(Pt 16):3401-13. doi: 10.1242/jcs.145029. Review.


MarvelD3 couples tight junctions to the MEKK1-JNK pathway to regulate cell behavior and survival.

Steed E, Elbediwy A, Vacca B, Dupasquier S, Hemkemeyer SA, Suddason T, Costa AC, Beaudry JB, Zihni C, Gallagher E, Pierreux CE, Balda MS, Matter K.

J Cell Biol. 2014 Mar 3;204(5):821-38. doi: 10.1083/jcb.201304115. Epub 2014 Feb 24.


Dbl3 drives Cdc42 signaling at the apical margin to regulate junction position and apical differentiation.

Zihni C, Munro PM, Elbediwy A, Keep NH, Terry SJ, Harris J, Balda MS, Matter K.

J Cell Biol. 2014 Jan 6;204(1):111-27. doi: 10.1083/jcb.201304064. Epub 2013 Dec 30.


Stimulation of cortical myosin phosphorylation by p114RhoGEF drives cell migration and tumor cell invasion.

Terry SJ, Elbediwy A, Zihni C, Harris AR, Bailly M, Charras GT, Balda MS, Matter K.

PLoS One. 2012;7(11):e50188. doi: 10.1371/journal.pone.0050188. Epub 2012 Nov 19.


Epithelial junction formation requires confinement of Cdc42 activity by a novel SH3BP1 complex.

Elbediwy A, Zihni C, Terry SJ, Clark P, Matter K, Balda MS.

J Cell Biol. 2012 Aug 20;198(4):677-93. doi: 10.1083/jcb.201202094. Epub 2012 Aug 13.


Spatially restricted activation of RhoA signalling at epithelial junctions by p114RhoGEF drives junction formation and morphogenesis.

Terry SJ, Zihni C, Elbediwy A, Vitiello E, Leefa Chong San IV, Balda MS, Matter K.

Nat Cell Biol. 2011 Feb;13(2):159-66. doi: 10.1038/ncb2156. Epub 2011 Jan 23.


Morphometric analysis of small-bowel mucosa in Turkish children with celiac disease and relationship with the clinical presentation and laboratory findings.

Arikan C, Zihni C, Cakir M, Alkanat M, Aydogdu S.

Dig Dis Sci. 2007 Sep;52(9):2133-9. Epub 2007 Apr 4.


Prostate-derived sterile 20-like kinase 1-alpha induces apoptosis. JNK- and caspase-dependent nuclear localization is a requirement for membrane blebbing.

Zihni C, Mitsopoulos C, Tavares IA, Baum B, Ridley AJ, Morris JD.

J Biol Chem. 2007 Mar 2;282(9):6484-93. Epub 2006 Dec 11.


Prostate-derived sterile 20-like kinase 2 (PSK2) regulates apoptotic morphology via C-Jun N-terminal kinase and Rho kinase-1.

Zihni C, Mitsopoulos C, Tavares IA, Ridley AJ, Morris JD.

J Biol Chem. 2006 Mar 17;281(11):7317-23. Epub 2006 Jan 2.


The prostate-derived sterile 20-like kinase (PSK) regulates microtubule organization and stability.

Mitsopoulos C, Zihni C, Garg R, Ridley AJ, Morris JD.

J Biol Chem. 2003 May 16;278(20):18085-91. Epub 2003 Mar 13.


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