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Items: 1 to 50 of 80

1.

Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 5p15.33 TERT-CLPTM1Ll Region.

Hung RJ, Spitz MR, Houlston RS, Schwartz AG, Field JK, Ying J, Li Y, Han Y, Ji X, Chen W, Wu X, Gorlov IP, Na J, de Andrade M, Liu G, Brhane Y, Diao N, Wenzlaff A, Davies MPA, Liloglou T, Timofeeva M, Muley T, Rennert H, Saliba W, Ryan BM, Bowman E, Barros-Dios JM, Pérez-Ríos M, Morgenstern H, Zienolddiny S, Skaug V, Ugolini D, Bonassi S, van der Heijden EHFM, Tardon A, Bojesen SE, Landi MT, Johansson M, Bickeböller H, Arnold S, Le Marchand L, Melander O, Andrew A, Grankvist K, Caporaso N, Teare MD, Schabath MB, Aldrich MC, Kiemeney LA, Wichmann HE, Lazarus P, Mayordomo J, Neri M, Haugen A, Zhang ZF, Ruano-Raviña A, Brenner H, Harris CC, Orlow I, Rennert G, Risch A, Brennan P, Christiani DC, Amos CI, Yang P, Gorlova OY.

J Thorac Oncol. 2019 Aug;14(8):1360-1369. doi: 10.1016/j.jtho.2019.04.008. Epub 2019 Apr 19.

2.

Genetic interaction analysis among oncogenesis-related genes revealed novel genes and networks in lung cancer development.

Li Y, Xiao X, Bossé Y, Gorlova O, Gorlov I, Han Y, Byun J, Leighl N, Johansen JS, Barnett M, Chen C, Goodman G, Cox A, Taylor F, Woll P, Wichmann HE, Manz J, Muley T, Risch A, Rosenberger A, Han J, Siminovitch K, Arnold SM, Haura EB, Bolca C, Holcatova I, Janout V, Kontic M, Lissowska J, Mukeria A, Ognjanovic S, Orlowski TM, Scelo G, Swiatkowska B, Zaridze D, Bakke P, Skaug V, Zienolddiny S, Duell EJ, Butler LM, Houlston R, Artigas MS, Grankvist K, Johansson M, Shepherd FA, Marcus MW, Brunnström H, Manjer J, Melander O, Muller DC, Overvad K, Trichopoulou A, Tumino R, Liu G, Bojesen SE, Wu X, Le Marchand L, Albanes D, Bickeböller H, Aldrich MC, Bush WS, Tardon A, Rennert G, Teare MD, Field JK, Kiemeney LA, Lazarus P, Haugen A, Lam S, Schabath MB, Andrew AS, Bertazzi PA, Pesatori AC, Christiani DC, Caporaso N, Johansson M, McKay JD, Brennan P, Hung RJ, Amos CI.

Oncotarget. 2019 Mar 5;10(19):1760-1774. doi: 10.18632/oncotarget.26678. eCollection 2019 Mar 5.

3.

Cellulose nanocrystals modulate alveolar macrophage phenotype and phagocytic function.

Samulin Erdem J, Alswady-Hoff M, Ervik TK, Skare Ø, Ellingsen DG, Zienolddiny S.

Biomaterials. 2019 May;203:31-42. doi: 10.1016/j.biomaterials.2019.02.025. Epub 2019 Feb 28.

4.

Mechanisms of Toxicity of Industrially Relevant Silicomanganese Dust on Human 1321N1 Astrocytoma Cells: An In Vitro Study.

Arnoldussen YJ, Kringlen Ervik T, Samulin Erdem J, Kero I, Baarnes Eriksen M, Skaug V, Zienolddiny S.

Int J Mol Sci. 2019 Feb 10;20(3). pii: E740. doi: 10.3390/ijms20030740.

5.

Elevated Platelet Count Appears to Be Causally Associated with Increased Risk of Lung Cancer: A Mendelian Randomization Analysis.

Zhu Y, Wei Y, Zhang R, Dong X, Shen S, Zhao Y, Bai J, Albanes D, Caporaso NE, Landi MT, Zhu B, Chanock SJ, Gu F, Lam S, Tsao MS, Shepherd FA, Tardon A, Fernández-Somoano A, Fernandez-Tardon G, Chen C, Barnett MJ, Doherty J, Bojesen SE, Johansson M, Brennan P, McKay JD, Carreras-Torres R, Muley T, Risch A, Wichmann HE, Bickeboeller H, Rosenberger A, Rennert G, Saliba W, Arnold SM, Field JK, Davies MPA, Marcus MW, Wu X, Ye Y, Le Marchand L, Wilkens LR, Melander O, Manjer J, Brunnström H, Hung RJ, Liu G, Brhane Y, Kachuri L, Andrew AS, Duell EJ, Kiemeney LA, van der Heijden EH, Haugen A, Zienolddiny S, Skaug V, Grankvist K, Johansson M, Woll PJ, Cox A, Taylor F, Teare DM, Lazarus P, Schabath MB, Aldrich MC, Houlston RS, McLaughlin J, Stevens VL, Shen H, Hu Z, Dai J, Amos CI, Han Y, Zhu D, Goodman GE, Chen F, Christiani DC.

Cancer Epidemiol Biomarkers Prev. 2019 May;28(5):935-942. doi: 10.1158/1055-9965.EPI-18-0356. Epub 2019 Jan 30.

PMID:
30700444
6.

Shared heritability and functional enrichment across six solid cancers.

Jiang X, Finucane HK, Schumacher FR, Schmit SL, Tyrer JP, Han Y, Michailidou K, Lesseur C, Kuchenbaecker KB, Dennis J, Conti DV, Casey G, Gaudet MM, Huyghe JR, Albanes D, Aldrich MC, Andrew AS, Andrulis IL, Anton-Culver H, Antoniou AC, Antonenkova NN, Arnold SM, Aronson KJ, Arun BK, Bandera EV, Barkardottir RB, Barnes DR, Batra J, Beckmann MW, Benitez J, Benlloch S, Berchuck A, Berndt SI, Bickeböller H, Bien SA, Blomqvist C, Boccia S, Bogdanova NV, Bojesen SE, Bolla MK, Brauch H, Brenner H, Brenton JD, Brook MN, Brunet J, Brunnström H, Buchanan DD, Burwinkel B, Butzow R, Cadoni G, Caldés T, Caligo MA, Campbell I, Campbell PT, Cancel-Tassin G, Cannon-Albright L, Campa D, Caporaso N, Carvalho AL, Chan AT, Chang-Claude J, Chanock SJ, Chen C, Christiani DC, Claes KBM, Claessens F, Clements J, Collée JM, Correa MC, Couch FJ, Cox A, Cunningham JM, Cybulski C, Czene K, Daly MB, deFazio A, Devilee P, Diez O, Gago-Dominguez M, Donovan JL, Dörk T, Duell EJ, Dunning AM, Dwek M, Eccles DM, Edlund CK, Edwards DRV, Ellberg C, Evans DG, Fasching PA, Ferris RL, Liloglou T, Figueiredo JC, Fletcher O, Fortner RT, Fostira F, Franceschi S, Friedman E, Gallinger SJ, Ganz PA, Garber J, García-Sáenz JA, Gayther SA, Giles GG, Godwin AK, Goldberg MS, Goldgar DE, Goode EL, Goodman MT, Goodman G, Grankvist K, Greene MH, Gronberg H, Gronwald J, Guénel P, Håkansson N, Hall P, Hamann U, Hamdy FC, Hamilton RJ, Hampe J, Haugen A, Heitz F, Herrero R, Hillemanns P, Hoffmeister M, Høgdall E, Hong YC, Hopper JL, Houlston R, Hulick PJ, Hunter DJ, Huntsman DG, Idos G, Imyanitov EN, Ingles SA, Isaacs C, Jakubowska A, James P, Jenkins MA, Johansson M, Johansson M, John EM, Joshi AD, Kaneva R, Karlan BY, Kelemen LE, Kühl T, Khaw KT, Khusnutdinova E, Kibel AS, Kiemeney LA, Kim J, Kjaer SK, Knight JA, Kogevinas M, Kote-Jarai Z, Koutros S, Kristensen VN, Kupryjanczyk J, Lacko M, Lam S, Lambrechts D, Landi MT, Lazarus P, Le ND, Lee E, Lejbkowicz F, Lenz HJ, Leslie G, Lessel D, Lester J, Levine DA, Li L, Li CI, Lindblom A, Lindor NM, Liu G, Loupakis F, Lubiński J, Maehle L, Maier C, Mannermaa A, Marchand LL, Margolin S, May T, McGuffog L, Meindl A, Middha P, Miller A, Milne RL, MacInnis RJ, Modugno F, Montagna M, Moreno V, Moysich KB, Mucci L, Muir K, Mulligan AM, Nathanson KL, Neal DE, Ness AR, Neuhausen SL, Nevanlinna H, Newcomb PA, Newcomb LF, Nielsen FC, Nikitina-Zake L, Nordestgaard BG, Nussbaum RL, Offit K, Olah E, Olama AAA, Olopade OI, Olshan AF, Olsson H, Osorio A, Pandha H, Park JY, Pashayan N, Parsons MT, Pejovic T, Penney KL, Peters WHM, Phelan CM, Phipps AI, Plaseska-Karanfilska D, Pring M, Prokofyeva D, Radice P, Stefansson K, Ramus SJ, Raskin L, Rennert G, Rennert HS, van Rensburg EJ, Riggan MJ, Risch HA, Risch A, Roobol MJ, Rosenstein BS, Rossing MA, De Ruyck K, Saloustros E, Sandler DP, Sawyer EJ, Schabath MB, Schleutker J, Schmidt MK, Setiawan VW, Shen H, Siegel EM, Sieh W, Singer CF, Slattery ML, Sorensen KD, Southey MC, Spurdle AB, Stanford JL, Stevens VL, Stintzing S, Stone J, Sundfeldt K, Sutphen R, Swerdlow AJ, Tajara EH, Tangen CM, Tardon A, Taylor JA, Teare MD, Teixeira MR, Terry MB, Terry KL, Thibodeau SN, Thomassen M, Bjørge L, Tischkowitz M, Toland AE, Torres D, Townsend PA, Travis RC, Tung N, Tworoger SS, Ulrich CM, Usmani N, Vachon CM, Van Nieuwenhuysen E, Vega A, Aguado-Barrera ME, Wang Q, Webb PM, Weinberg CR, Weinstein S, Weissler MC, Weitzel JN, West CML, White E, Whittemore AS, Wichmann HE, Wiklund F, Winqvist R, Wolk A, Woll P, Woods M, Wu AH, Wu X, Yannoukakos D, Zheng W, Zienolddiny S, Ziogas A, Zorn KK, Lane JM, Saxena R, Thomas D, Hung RJ, Diergaarde B, McKay J, Peters U, Hsu L, García-Closas M, Eeles RA, Chenevix-Trench G, Brennan PJ, Haiman CA, Simard J, Easton DF, Gruber SB, Pharoah PDP, Price AL, Pasaniuc B, Amos CI, Kraft P, Lindström S.

Nat Commun. 2019 Jan 25;10(1):431. doi: 10.1038/s41467-018-08054-4.

7.

Cellular Responses of Industrially Relevant Silica Dust on Human Glial Cells In Vitro.

Arnoldussen YJ, Kringlen Ervik T, Baarnes Eriksen M, Kero I, Skaug V, Zienolddiny S.

Int J Mol Sci. 2019 Jan 16;20(2). pii: E358. doi: 10.3390/ijms20020358.

8.

Systematic analyses of regulatory variants in DNase I hypersensitive sites identified two novel lung cancer susceptibility loci.

Dai J, Li Z, Amos CI, Hung RJ, Tardon A, Andrew AS, Chen C, Christiani DC, Albanes D, van der Heijden EHFM, Duell EJ, Rennert G, Mckay JD, Yuan JM, Field JK, Manjer J, Grankvist K, Le Marchand L, Teare MD, Schabath MB, Aldrich MC, Tsao MS, Lazarus P, Lam S, Bojesen SE, Arnold S, Wu X, Haugen A, Janout V, Johansson M, Brhane Y, Fernandez-Somoano A, Kiemeney LA, Davies MPA, Zienolddiny S, Hu Z, Shen H.

Carcinogenesis. 2019 May 14;40(3):432-440. doi: 10.1093/carcin/bgy187.

PMID:
30590402
9.

Fine mapping of MHC region in lung cancer highlights independent susceptibility loci by ethnicity.

Ferreiro-Iglesias A, Lesseur C, McKay J, Hung RJ, Han Y, Zong X, Christiani D, Johansson M, Xiao X, Li Y, Qian DC, Ji X, Liu G, Caporaso N, Scelo G, Zaridze D, Mukeriya A, Kontic M, Ognjanovic S, Lissowska J, Szołkowska M, Swiatkowska B, Janout V, Holcatova I, Bolca C, Savic M, Ognjanovic M, Bojesen SE, Wu X, Albanes D, Aldrich MC, Tardon A, Fernandez-Somoano A, Fernandez-Tardon G, Le Marchand L, Rennert G, Chen C, Doherty J, Goodman G, Bickeböller H, Wichmann HE, Risch A, Rosenberger A, Shen H, Dai J, Field JK, Davies M, Woll P, Teare MD, Kiemeney LA, van der Heijden EHFM, Yuan JM, Hong YC, Haugen A, Zienolddiny S, Lam S, Tsao MS, Johansson M, Grankvist K, Schabath MB, Andrew A, Duell E, Melander O, Brunnström H, Lazarus P, Arnold S, Slone S, Byun J, Kamal A, Zhu D, Landi MT, Amos CI, Brennan P.

Nat Commun. 2018 Sep 25;9(1):3927. doi: 10.1038/s41467-018-05890-2.

10.

Epigenetic Basis of Circadian Rhythm Disruption in Cancer.

Reszka E, Zienolddiny S.

Methods Mol Biol. 2018;1856:173-201. doi: 10.1007/978-1-4939-8751-1_10. Review. Erratum in: Methods Mol Biol. 2018;1856:C1.

PMID:
30178252
11.

Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk.

Ji X, Bossé Y, Landi MT, Gui J, Xiao X, Qian D, Joubert P, Lamontagne M, Li Y, Gorlov I, de Biasi M, Han Y, Gorlova O, Hung RJ, Wu X, McKay J, Zong X, Carreras-Torres R, Christiani DC, Caporaso N, Johansson M, Liu G, Bojesen SE, Le Marchand L, Albanes D, Bickeböller H, Aldrich MC, Bush WS, Tardon A, Rennert G, Chen C, Teare MD, Field JK, Kiemeney LA, Lazarus P, Haugen A, Lam S, Schabath MB, Andrew AS, Shen H, Hong YC, Yuan JM, Bertazzi PA, Pesatori AC, Ye Y, Diao N, Su L, Zhang R, Brhane Y, Leighl N, Johansen JS, Mellemgaard A, Saliba W, Haiman C, Wilkens L, Fernandez-Somoano A, Fernandez-Tardon G, van der Heijden EHFM, Kim JH, Dai J, Hu Z, Davies MPA, Marcus MW, Brunnström H, Manjer J, Melander O, Muller DC, Overvad K, Trichopoulou A, Tumino R, Doherty J, Goodman GE, Cox A, Taylor F, Woll P, Brüske I, Manz J, Muley T, Risch A, Rosenberger A, Grankvist K, Johansson M, Shepherd F, Tsao MS, Arnold SM, Haura EB, Bolca C, Holcatova I, Janout V, Kontic M, Lissowska J, Mukeria A, Ognjanovic S, Orlowski TM, Scelo G, Swiatkowska B, Zaridze D, Bakke P, Skaug V, Zienolddiny S, Duell EJ, Butler LM, Koh WP, Gao YT, Houlston R, McLaughlin J, Stevens V, Nickle DC, Obeidat M, Timens W, Zhu B, Song L, Artigas MS, Tobin MD, Wain LV, Gu F, Byun J, Kamal A, Zhu D, Tyndale RF, Wei WQ, Chanock S, Brennan P, Amos CI.

Nat Commun. 2018 Aug 13;9(1):3221. doi: 10.1038/s41467-018-05074-y.

12.

Mendelian Randomization and mediation analysis of leukocyte telomere length and risk of lung and head and neck cancers.

Kachuri L, Saarela O, Bojesen SE, Davey Smith G, Liu G, Landi MT, Caporaso NE, Christiani DC, Johansson M, Panico S, Overvad K, Trichopoulou A, Vineis P, Scelo G, Zaridze D, Wu X, Albanes D, Diergaarde B, Lagiou P, Macfarlane GJ, Aldrich MC, Tardón A, Rennert G, Olshan AF, Weissler MC, Chen C, Goodman GE, Doherty JA, Ness AR, Bickeböller H, Wichmann HE, Risch A, Field JK, Teare MD, Kiemeney LA, van der Heijden EHFM, Carroll JC, Haugen A, Zienolddiny S, Skaug V, Wünsch-Filho V, Tajara EH, Ayoub Moysés R, Daumas Nunes F, Lam S, Eluf-Neto J, Lacko M, Peters WHM, Le Marchand L, Duell EJ, Andrew AS, Franceschi S, Schabath MB, Manjer J, Arnold S, Lazarus P, Mukeriya A, Swiatkowska B, Janout V, Holcatova I, Stojsic J, Mates D, Lissowska J, Boccia S, Lesseur C, Zong X, McKay JD, Brennan P, Amos CI, Hung RJ.

Int J Epidemiol. 2019 Jun 1;48(3):751-766. doi: 10.1093/ije/dyy140.

13.

Genetic modifiers of radon-induced lung cancer risk: a genome-wide interaction study in former uranium miners.

Rosenberger A, Hung RJ, Christiani DC, Caporaso NE, Liu G, Bojesen SE, Le Marchand L, Haiman CA, Albanes D, Aldrich MC, Tardon A, Fernández-Tardón G, Rennert G, Field JK, Kiemeney B, Lazarus P, Haugen A, Zienolddiny S, Lam S, Schabath MB, Andrew AS, Brunnsstöm H, Goodman GE, Doherty JA, Chen C, Teare MD, Wichmann HE, Manz J, Risch A, Muley TR, Johansson M, Brennan P, Landi MT, Amos CI, Pesch B, Johnen G, Brüning T, Bickeböller H, Gomolka M.

Int Arch Occup Environ Health. 2018 Nov;91(8):937-950. doi: 10.1007/s00420-018-1334-3. Epub 2018 Jul 3.

14.

Inflammation in the pleural cavity following injection of multi-walled carbon nanotubes is dependent on their characteristics and the presence of IL-1 genes.

Arnoldussen YJ, Skaug V, Aleksandersen M, Ropstad E, Anmarkrud KH, Einarsdottir E, Chin-Lin F, Granum Bjørklund C, Kasem M, Eilertsen E, Apte RN, Zienolddiny S.

Nanotoxicology. 2018 Aug;12(6):522-538. doi: 10.1080/17435390.2018.1465139. Epub 2018 May 9.

PMID:
29742950
15.

Criteria for grouping of manufactured nanomaterials to facilitate hazard and risk assessment, a systematic review of expert opinions.

Landvik NE, Skaug V, Mohr B, Verbeek J, Zienolddiny S.

Regul Toxicol Pharmacol. 2018 Jun;95:270-279. doi: 10.1016/j.yrtph.2018.03.027. Epub 2018 Mar 31. Review.

16.

Characterization of the proteome and lipidome profiles of human lung cells after low dose and chronic exposure to multiwalled carbon nanotubes.

Phuyal S, Kasem M, Knittelfelder O, Sharma A, Fonseca DM, Vebraite V, Shaposhnikov S, Slupphaug G, Skaug V, Zienolddiny S.

Nanotoxicology. 2018 Mar;12(2):138-152. doi: 10.1080/17435390.2018.1425500. Epub 2018 Jan 19.

PMID:
29350075
17.

Correction to: Epigenetic Basis of Circadian Rhythm Disruption in Cancer.

Reszka E, Zienolddiny S.

Methods Mol Biol. 2018;1856:C1. doi: 10.1007/978-1-4939-8751-1_18.

PMID:
30850986
18.

Decreased macrophage phagocytic function due to xenobiotic exposures in vitro, difference in sensitivity between various macrophage models.

Berntsen HF, Bølling AK, Bjørklund CG, Zimmer K, Ropstad E, Zienolddiny S, Becher R, Holme JA, Dirven H, Nygaard UC, Bodin J.

Food Chem Toxicol. 2018 Feb;112:86-96. doi: 10.1016/j.fct.2017.12.024. Epub 2017 Dec 16.

PMID:
29258957
19.

Circadian gene methylation in rotating-shift nurses: a cross-sectional study.

Reszka E, Wieczorek E, Przybek M, Jabłońska E, Kałużny P, Bukowska-Damska A, Zienolddiny S, Pepłońska B.

Chronobiol Int. 2018 Jan;35(1):111-121. doi: 10.1080/07420528.2017.1388252. Epub 2017 Nov 16.

PMID:
29144171
20.

Sleep quality and methylation status of selected tumor suppressor genes among nurses and midwives.

Bukowska-Damska A, Reszka E, Kaluzny P, Wieczorek E, Przybek M, Zienolddiny S, Peplonska B.

Chronobiol Int. 2018 Jan;35(1):122-131. doi: 10.1080/07420528.2017.1376219. Epub 2017 Nov 16.

PMID:
29144154
21.

Cellular responses of human astrocytoma cells to dust from the Acheson process: An in vitro study.

Arnoldussen YJ, Ervik TK, Berlinger B, Kero I, Shaposhnikov S, Zienolddiny S.

Neurotoxicology. 2018 Mar;65:241-247. doi: 10.1016/j.neuro.2017.11.001. Epub 2017 Nov 4.

22.

Sleep quality and methylation status of core circadian rhythm genes among nurses and midwives.

Bukowska-Damska A, Reszka E, Kaluzny P, Wieczorek E, Przybek M, Zienolddiny S, Peplonska B.

Chronobiol Int. 2017;34(9):1211-1223. doi: 10.1080/07420528.2017.1358176. Epub 2017 Nov 6.

PMID:
29106308
23.

Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk in Caucasian population.

Li Y, Xiao X, Han Y, Gorlova O, Qian D, Leighl N, Johansen JS, Barnett M, Chen C, Goodman G, Cox A, Taylor F, Woll P, Wichmann HE, Manz J, Muley T, Risch A, Rosenberger A, Arnold SM, Haura EB, Bolca C, Holcatova I, Janout V, Kontic M, Lissowska J, Mukeria A, Ognjanovic S, Orlowski TM, Scelo G, Swiatkowska B, Zaridze D, Bakke P, Skaug V, Zienolddiny S, Duell EJ, Butler LM, Houlston R, Soler Artigas M, Grankvist K, Johansson M, Shepherd FA, Marcus MW, Brunnström H, Manjer J, Melander O, Muller DC, Overvad K, Trichopoulou A, Tumino R, Liu G, Bojesen SE, Wu X, Marchand LL, Albanes D, Bickeböller H, Aldrich MC, Bush WS, Tardon A, Rennert G, Teare MD, Field JK, Kiemeney LA, Lazarus P, Haugen A, Lam S, Schabath MB, Andrew AS, Bertazzi PA, Pesatori AC, Christiani DC, Caporaso N, Johansson M, McKay JD, Brennan P, Hung RJ, Amos CI.

Carcinogenesis. 2018 Mar 8;39(3):336-346. doi: 10.1093/carcin/bgx113.

24.

Mechanisms of Breast Cancer in Shift Workers: DNA Methylation in Five Core Circadian Genes in Nurses Working Night Shifts.

Samulin Erdem J, Skare Ø, Petersen-Øverleir M, Notø HØ, Lie JS, Reszka E, Pepłońska B, Zienolddiny S.

J Cancer. 2017 Aug 24;8(15):2876-2884. doi: 10.7150/jca.21064. eCollection 2017.

25.

Effects on human bronchial epithelial cells following low-dose chronic exposure to nanomaterials: A 6-month transformation study.

Phuyal S, Kasem M, Rubio L, Karlsson HL, Marcos R, Skaug V, Zienolddiny S.

Toxicol In Vitro. 2017 Oct;44:230-240. doi: 10.1016/j.tiv.2017.07.016. Epub 2017 Jul 23.

PMID:
28746895
26.

Mechanisms of breast cancer risk in shift workers: association of telomere shortening with the duration and intensity of night work.

Samulin Erdem J, Notø HØ, Skare Ø, Lie JS, Petersen-Øverleir M, Reszka E, Pepłońska B, Zienolddiny S.

Cancer Med. 2017 Aug;6(8):1988-1997. doi: 10.1002/cam4.1135. Epub 2017 Jul 14.

27.

Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

McKay JD, Hung RJ, Han Y, Zong X, Carreras-Torres R, Christiani DC, Caporaso NE, Johansson M, Xiao X, Li Y, Byun J, Dunning A, Pooley KA, Qian DC, Ji X, Liu G, Timofeeva MN, Bojesen SE, Wu X, Le Marchand L, Albanes D, Bickeböller H, Aldrich MC, Bush WS, Tardon A, Rennert G, Teare MD, Field JK, Kiemeney LA, Lazarus P, Haugen A, Lam S, Schabath MB, Andrew AS, Shen H, Hong YC, Yuan JM, Bertazzi PA, Pesatori AC, Ye Y, Diao N, Su L, Zhang R, Brhane Y, Leighl N, Johansen JS, Mellemgaard A, Saliba W, Haiman CA, Wilkens LR, Fernandez-Somoano A, Fernandez-Tardon G, van der Heijden HFM, Kim JH, Dai J, Hu Z, Davies MPA, Marcus MW, Brunnström H, Manjer J, Melander O, Muller DC, Overvad K, Trichopoulou A, Tumino R, Doherty JA, Barnett MP, Chen C, Goodman GE, Cox A, Taylor F, Woll P, Brüske I, Wichmann HE, Manz J, Muley TR, Risch A, Rosenberger A, Grankvist K, Johansson M, Shepherd FA, Tsao MS, Arnold SM, Haura EB, Bolca C, Holcatova I, Janout V, Kontic M, Lissowska J, Mukeria A, Ognjanovic S, Orlowski TM, Scelo G, Swiatkowska B, Zaridze D, Bakke P, Skaug V, Zienolddiny S, Duell EJ, Butler LM, Koh WP, Gao YT, Houlston RS, McLaughlin J, Stevens VL, Joubert P, Lamontagne M, Nickle DC, Obeidat M, Timens W, Zhu B, Song L, Kachuri L, Artigas MS, Tobin MD, Wain LV; SpiroMeta Consortium, Rafnar T, Thorgeirsson TE, Reginsson GW, Stefansson K, Hancock DB, Bierut LJ, Spitz MR, Gaddis NC, Lutz SM, Gu F, Johnson EO, Kamal A, Pikielny C, Zhu D, Lindströem S, Jiang X, Tyndale RF, Chenevix-Trench G, Beesley J, Bossé Y, Chanock S, Brennan P, Landi MT, Amos CI.

Nat Genet. 2017 Jul;49(7):1126-1132. doi: 10.1038/ng.3892. Epub 2017 Jun 12.

28.

Rotating night work, lifestyle factors, obesity and promoter methylation in BRCA1 and BRCA2 genes among nurses and midwives.

Peplonska B, Bukowska A, Wieczorek E, Przybek M, Zienolddiny S, Reszka E.

PLoS One. 2017 Jun 8;12(6):e0178792. doi: 10.1371/journal.pone.0178792. eCollection 2017.

29.

Copy number variation, increased gene expression, and molecular mechanisms of neurofascin in lung cancer.

Samulin Erdem J, Arnoldussen YJ, Skaug V, Haugen A, Zienolddiny S.

Mol Carcinog. 2017 Sep;56(9):2076-2085. doi: 10.1002/mc.22664. Epub 2017 May 2.

30.

In vitro genotoxicity testing of four reference metal nanomaterials, titanium dioxide, zinc oxide, cerium oxide and silver: towards reliable hazard assessment.

El Yamani N, Collins AR, Rundén-Pran E, Fjellsbø LM, Shaposhnikov S, Zienolddiny S, Dusinska M.

Mutagenesis. 2017 Jan;32(1):117-126. doi: 10.1093/mutage/gew060. Epub 2016 Nov 12. Erratum in: Mutagenesis. 2017 May 1;32(3):409.

PMID:
27838631
31.

Genetic Risk Can Be Decreased: Quitting Smoking Decreases and Delays Lung Cancer for Smokers With High and Low CHRNA5 Risk Genotypes - A Meta-Analysis.

Chen LS, Baker T, Hung RJ, Horton A, Culverhouse R, Hartz S, Saccone N, Cheng I, Deng B, Han Y, Hansen HM, Horsman J, Kim C, Rosenberger A, Aben KK, Andrew AS, Chang SC, Saum KU, Dienemann H, Hatsukami DK, Johnson EO, Pande M, Wrensch MR, McLaughlin J, Skaug V, van der Heijden EH, Wampfler J, Wenzlaff A, Woll P, Zienolddiny S, Bickeböller H, Brenner H, Duell EJ, Haugen A, Brüske I, Kiemeney LA, Lazarus P, Le Marchand L, Liu G, Mayordomo J, Risch A, Schwartz AG, Teare MD, Wu X, Wiencke JK, Yang P, Zhang ZF, Spitz MR, Amos CI, Bierut LJ.

EBioMedicine. 2016 Sep;11:219-226. doi: 10.1016/j.ebiom.2016.08.012. Epub 2016 Aug 10.

32.

Night shift work and other determinants of estradiol, testosterone, and dehydroepiandrosterone sulfate among middle-aged nurses and midwives.

Peplonska B, Bukowska A, Lie JA, Gromadzinska J, Zienolddiny S.

Scand J Work Environ Health. 2016 Sep 1;42(5):435-46. doi: 10.5271/sjweh.3581. Epub 2016 Aug 8.

33.

Effects of carbon nanotubes on intercellular communication and involvement of IL-1 genes.

Arnoldussen YJ, Anmarkrud KH, Skaug V, Apte RN, Haugen A, Zienolddiny S.

J Cell Commun Signal. 2016 Jun;10(2):153-62. doi: 10.1007/s12079-016-0323-0. Epub 2016 Apr 21.

34.

Loss of MKK3 and MK2 Copy Numbers in Non-Small Cell Lung Cancer.

Samulin Erdem J, Skaug V, Haugen A, Zienolddiny S.

J Cancer. 2016 Feb 5;7(5):512-5. doi: 10.7150/jca.13651. eCollection 2016.

35.

A rare missense mutation in CHRNA4 associates with smoking behavior and its consequences.

Thorgeirsson TE, Steinberg S, Reginsson GW, Bjornsdottir G, Rafnar T, Jonsdottir I, Helgadottir A, Gretarsdottir S, Helgadottir H, Jonsson S, Matthiasson SE, Gislason T, Tyrfingsson T, Gudbjartsson T, Isaksson HJ, Hardardottir H, Sigvaldason A, Kiemeney LA, Haugen A, Zienolddiny S, Wolf HJ, Franklin WA, Panadero A, Mayordomo JI, Hall IP, Rönmark E, Lundbäck B, Dirksen A, Ashraf H, Pedersen JH, Masson G, Sulem P, Thorsteinsdottir U, Gudbjartsson DF, Stefansson K.

Mol Psychiatry. 2016 May;21(5):594-600. doi: 10.1038/mp.2016.13. Epub 2016 Mar 8.

36.

Mutations in TP53 increase the risk of SOX2 copy number alterations and silencing of TP53 reduces SOX2 expression in non-small cell lung cancer.

Samulin Erdem J, Skaug V, Bakke P, Gulsvik A, Haugen A, Zienolddiny S.

BMC Cancer. 2016 Jan 19;16:28. doi: 10.1186/s12885-016-2061-3.

37.

Association of the FAM46A gene VNTRs and BAG6 rs3117582 SNP with non small cell lung cancer (NSCLC) in Croatian and Norwegian populations.

Etokebe GE, Zienolddiny S, Kupanovac Z, Enersen M, Balen S, Flego V, Bulat-Kardum L, Radojčić-Badovinac A, Skaug V, Bakke P, Haugen A, Dembic Z.

PLoS One. 2015 Apr 17;10(4):e0122651. doi: 10.1371/journal.pone.0122651. eCollection 2015.

38.

CHRNA5 risk variant predicts delayed smoking cessation and earlier lung cancer diagnosis--a meta-analysis.

Chen LS, Hung RJ, Baker T, Horton A, Culverhouse R, Saccone N, Cheng I, Deng B, Han Y, Hansen HM, Horsman J, Kim C, Lutz S, Rosenberger A, Aben KK, Andrew AS, Breslau N, Chang SC, Dieffenbach AK, Dienemann H, Frederiksen B, Han J, Hatsukami DK, Johnson EO, Pande M, Wrensch MR, McLaughlin J, Skaug V, van der Heijden HF, Wampfler J, Wenzlaff A, Woll P, Zienolddiny S, Bickeböller H, Brenner H, Duell EJ, Haugen A, Heinrich J, Hokanson JE, Hunter DJ, Kiemeney LA, Lazarus P, Le Marchand L, Liu G, Mayordomo J, Risch A, Schwartz AG, Teare D, Wu X, Wiencke JK, Yang P, Zhang ZF, Spitz MR, Kraft P, Amos CI, Bierut LJ.

J Natl Cancer Inst. 2015 Apr 14;107(5). pii: djv100. doi: 10.1093/jnci/djv100. Print 2015 May. Review.

39.

Involvement of IL-1 genes in the cellular responses to carbon nanotube exposure.

Arnoldussen YJ, Skogstad A, Skaug V, Kasem M, Haugen A, Benker N, Weinbruch S, Apte RN, Zienolddiny S.

Cytokine. 2015 May;73(1):128-37. doi: 10.1016/j.cyto.2015.01.032. Epub 2015 Mar 6.

PMID:
25748835
40.

CTCF mediates the TERT enhancer-promoter interactions in lung cancer cells: identification of a novel enhancer region involved in the regulation of TERT gene.

Eldholm V, Haugen A, Zienolddiny S.

Int J Cancer. 2014 May 15;134(10):2305-13. doi: 10.1002/ijc.28570. Epub 2013 Nov 14.

41.

Analysis of polymorphisms in the circadian-related genes and breast cancer risk in Norwegian nurses working night shifts.

Zienolddiny S, Haugen A, Lie JA, Kjuus H, Anmarkrud KH, Kjærheim K.

Breast Cancer Res. 2013;15(4):R53.

42.

Breast cancer among nurses: is the intensity of night work related to hormone receptor status?

Lie JA, Kjuus H, Zienolddiny S, Haugen A, Kjærheim K.

Am J Epidemiol. 2013 Jul 1;178(1):110-7. doi: 10.1093/aje/kws428. Epub 2013 Jun 20.

PMID:
23788666
43.

Informed conditioning on clinical covariates increases power in case-control association studies.

Zaitlen N, Lindström S, Pasaniuc B, Cornelis M, Genovese G, Pollack S, Barton A, Bickeböller H, Bowden DW, Eyre S, Freedman BI, Friedman DJ, Field JK, Groop L, Haugen A, Heinrich J, Henderson BE, Hicks PJ, Hocking LJ, Kolonel LN, Landi MT, Langefeld CD, Le Marchand L, Meister M, Morgan AW, Raji OY, Risch A, Rosenberger A, Scherf D, Steer S, Walshaw M, Waters KM, Wilson AG, Wordsworth P, Zienolddiny S, Tchetgen ET, Haiman C, Hunter DJ, Plenge RM, Worthington J, Christiani DC, Schaumberg DA, Chasman DI, Altshuler D, Voight B, Kraft P, Patterson N, Price AL.

PLoS Genet. 2012;8(11):e1003032. doi: 10.1371/journal.pgen.1003032. Epub 2012 Nov 8.

44.

Functional effect of polymorphisms in 15q25 locus on CHRNA5 mRNA, bulky DNA adducts and TP53 mutations.

Tekpli X, Landvik NE, Skaug V, Gulsvik A, Haugen A, Zienolddiny S.

Int J Cancer. 2013 Apr 15;132(8):1811-20. doi: 10.1002/ijc.27870. Epub 2012 Oct 20. Erratum in: Int J Cancer. 2014 Nov 15;135(10):E12.

45.

Functional analysis of a lung cancer risk haplotype in the IL1B gene regulatory region.

Landvik NE, Hart K, Haugen A, Zienolddiny S.

J Hum Genet. 2012 Nov 26;57(11):747-52. doi: 10.1038/jhg.2012.106. Epub 2012 Sep 6.

PMID:
22951596
46.

DNA methylation at promoter regions of interleukin 1B, interleukin 6, and interleukin 8 in non-small cell lung cancer.

Tekpli X, Landvik NE, Anmarkud KH, Skaug V, Haugen A, Zienolddiny S.

Cancer Immunol Immunother. 2013 Feb;62(2):337-45. doi: 10.1007/s00262-012-1340-3. Epub 2012 Aug 26.

PMID:
22923190
47.

Molecular characterization of a cancer-related single nucleotide polymorphism in the pro-inflammatory interleukin-1B gene.

Landvik NE, Tekpli X, Anmarkrud KH, Haugen A, Zienolddiny S.

Mol Carcinog. 2012 Oct;51 Suppl 1:E168-75. doi: 10.1002/mc.21910. Epub 2012 Mar 29.

PMID:
22467534
48.

DNA methylation of the CYP1A1 enhancer is associated with smoking-induced genetic alterations in human lung.

Tekpli X, Zienolddiny S, Skaug V, Stangeland L, Haugen A, Mollerup S.

Int J Cancer. 2012 Oct 1;131(7):1509-16. doi: 10.1002/ijc.27421. Epub 2012 Feb 28.

49.

Single nucleotide polymorphisms as susceptibility, prognostic, and therapeutic markers of nonsmall cell lung cancer.

Zienolddiny S, Skaug V.

Lung Cancer (Auckl). 2011 Dec 29;3:1-14. doi: 10.2147/LCTT.S13256. eCollection 2012. Review.

50.

Cigarette smoking increases copy number alterations in nonsmall-cell lung cancer.

Huang YT, Lin X, Liu Y, Chirieac LR, McGovern R, Wain J, Heist R, Skaug V, Zienolddiny S, Haugen A, Su L, Fox EA, Wong KK, Christiani DC.

Proc Natl Acad Sci U S A. 2011 Sep 27;108(39):16345-50. doi: 10.1073/pnas.1102769108. Epub 2011 Sep 12.

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