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Items: 1 to 50 of 198

1.

The German National Registry of Primary Immunodeficiencies (2012-2017).

El-Helou SM, Biegner AK, Bode S, Ehl SR, Heeg M, Maccari ME, Ritterbusch H, Speckmann C, Rusch S, Scheible R, Warnatz K, Atschekzei F, Beider R, Ernst D, Gerschmann S, Jablonka A, Mielke G, Schmidt RE, Schürmann G, Sogkas G, Baumann UH, Klemann C, Viemann D, von Bernuth H, Krüger R, Hanitsch LG, Scheibenbogen CM, Wittke K, Albert MH, Eichinger A, Hauck F, Klein C, Rack-Hoch A, Sollinger FM, Avila A, Borte M, Borte S, Fasshauer M, Hauenherm A, Kellner N, Müller AH, Ülzen A, Bader P, Bakhtiar S, Lee JY, Heß U, Schubert R, Wölke S, Zielen S, Ghosh S, Laws HJ, Neubert J, Oommen PT, Hönig M, Schulz A, Steinmann S, Schwarz K, Dückers G, Lamers B, Langemeyer V, Niehues T, Shai S, Graf D, Müglich C, Schmalzing MT, Schwaneck EC, Tony HP, Dirks J, Haase G, Liese JG, Morbach H, Foell D, Hellige A, Wittkowski H, Masjosthusmann K, Mohr M, Geberzahn L, Hedrich CM, Müller C, Rösen-Wolff A, Roesler J, Zimmermann A, Behrends U, Rieber N, Schauer U, Handgretinger R, Holzer U, Henes J, Kanz L, Boesecke C, Rockstroh JK, Schwarze-Zander C, Wasmuth JC, Dilloo D, Hülsmann B, Schönberger S, Schreiber S, Zeuner R, Ankermann T, von Bismarck P, Huppertz HI, Kaiser-Labusch P, Greil J, Jakoby D, Kulozik AE, Metzler M, Naumann-Bartsch N, Sobik B, Graf N, Heine S, Kobbe R, Lehmberg K, Müller I, Herrmann F, Horneff G, Klein A, Peitz J, Schmidt N, Bielack S, Groß-Wieltsch U, Classen CF, Klasen J, Deutz P, Kamitz D, Lassay L, Tenbrock K, Wagner N, Bernbeck B, Brummel B, Lara-Villacanas E, Münstermann E, Schneider DT, Tietsch N, Westkemper M, Weiß M, Kramm C, Kühnle I, Kullmann S, Girschick H, Specker C, Vinnemeier-Laubenthal E, Haenicke H, Schulz C, Schweigerer L, Müller TG, Stiefel M, Belohradsky BH, Soetedjo V, Kindle G, Grimbacher B.

Front Immunol. 2019 Jul 19;10:1272. doi: 10.3389/fimmu.2019.01272. eCollection 2019.

2.

Prospective comparison of a nonmodified and a modified mite extract for immunotherapy in children and adolescents.

Hartmann D, Fischl A, Herrmann E, Schulze J, Schubert R, Zielen S.

Immunotherapy. 2019 Aug;11(12):1015-1029. doi: 10.2217/imt-2019-0015. Epub 2019 Jul 19.

PMID:
31319714
3.

Predictors and reproducibility of exercise-induced bronchoconstriction in cold air.

Dreßler M, Friedrich T, Lasowski N, Herrmann E, Zielen S, Schulze J.

BMC Pulm Med. 2019 May 16;19(1):94. doi: 10.1186/s12890-019-0845-3.

4.

Impact of secondhand smoke on cystic fibrosis: is there a link to fatty acid metabolism?

Zielen S, Fussbroich D.

Thorax. 2019 Jun;74(6):529-530. doi: 10.1136/thoraxjnl-2019-213042. Epub 2019 May 2. No abstract available.

PMID:
31048510
5.

[Lung Function, Lung Clearance Index und Bronchial Inflammation in Children and Adolescents with Bronchiolitis obliterans].

Belachew N, Jerkic S, Michel F, Schubert R, Zielen S, Rosewich M.

Pneumologie. 2019 Jul;73(7):399-406. doi: 10.1055/a-0853-0253. Epub 2019 Mar 20. German.

PMID:
30895589
6.

Correlation of spirometry and body plethysmography during exercise-induced bronchial obstruction.

Schulze J, Smith HJ, Eichhorn C, Salzmann-Manrique E, Dreßler M, Zielen S.

Respir Med. 2019 Mar;148:54-59. doi: 10.1016/j.rmed.2019.01.011. Epub 2019 Jan 29.

PMID:
30827475
7.

Fast up-dosing with a birch allergoid is safe and well tolerated in allergic rhinitis patients with or without asthma.

Zielen S, Plückhahn K, Akboga Y, Rieker-Schwienbacher J, Thieme U, Rosewich M.

Immunotherapy. 2019 Feb;11(3):177-187. doi: 10.2217/imt-2018-0143.

PMID:
30730274
8.

A specific combined long-chain polyunsaturated fatty acid supplementation reverses fatty acid profile alterations in a mouse model of chronic asthma.

Fussbroich D, Zimmermann K, Göpel A, Eickmeier O, Trischler J, Zielen S, Schubert R, Beermann C.

Lipids Health Dis. 2019 Jan 18;18(1):16. doi: 10.1186/s12944-018-0947-6.

9.

AR101 Oral Immunotherapy for Peanut Allergy.

PALISADE Group of Clinical Investigators, Vickery BP, Vereda A, Casale TB, Beyer K, du Toit G, Hourihane JO, Jones SM, Shreffler WG, Marcantonio A, Zawadzki R, Sher L, Carr WW, Fineman S, Greos L, Rachid R, Ibáñez MD, Tilles S, Assa’ad AH, Nilsson C, Rupp N, Welch MJ, Sussman G, Chinthrajah S, Blumchen K, Sher E, Spergel JM, Leickly FE, Zielen S, Wang J, Sanders GM, Wood RA, Cheema A, Bindslev-Jensen C, Leonard S, Kachru R, Johnston DT, Hampel FC Jr, Kim EH, Anagnostou A, Pongracic JA, Ben-Shoshan M, Sharma HP, Stillerman A, Windom HH, Yang WH, Muraro A, Zubeldia JM, Sharma V, Dorsey MJ, Chong HJ, Ohayon J, Bird JA, Carr TF, Siri D, Fernández-Rivas M, Jeong DK, Fleischer DM, Lieberman JA, Dubois AEJ, Tsoumani M, Ciaccio CE, Portnoy JM, Mansfield LE, Fritz SB, Lanser BJ, Matz J, Oude Elberink HNG, Varshney P, Dilly SG, Adelman DC, Burks AW.

N Engl J Med. 2018 Nov 22;379(21):1991-2001. doi: 10.1056/NEJMoa1812856. Epub 2018 Nov 18.

PMID:
30449234
10.

Pre-emptive Allogeneic Hematopoietic Stem Cell Transplantation in Ataxia Telangiectasia.

Bakhtiar S, Woelke S, Huenecke S, Kieslich M, Taylor AM, Schubert R, Zielen S, Bader P.

Front Immunol. 2018 Oct 29;9:2495. doi: 10.3389/fimmu.2018.02495. eCollection 2018. Review.

11.

Ataxia telangiectasia alters the ApoB and reelin pathway.

Canet-Pons J, Schubert R, Duecker RP, Schrewe R, Wölke S, Kieslich M, Schnölzer M, Chiocchetti A, Auburger G, Zielen S, Warnken U.

Neurogenetics. 2018 Dec;19(4):237-255. doi: 10.1007/s10048-018-0557-5. Epub 2018 Oct 21.

PMID:
30343341
12.

Treatment of Granulomas in Patients With Ataxia Telangiectasia.

Woelke S, Valesky E, Bakhtiar S, Pommerening H, Pfeffermann LM, Schubert R, Zielen S.

Front Immunol. 2018 Sep 18;9:2000. doi: 10.3389/fimmu.2018.02000. eCollection 2018.

13.

Real-world benefits of allergen immunotherapy for birch pollen-associated allergic rhinitis and asthma.

Wahn U, Bachert C, Heinrich J, Richter H, Zielen S.

Allergy. 2019 Mar;74(3):594-604. doi: 10.1111/all.13598. Epub 2018 Oct 10.

14.

Cell distribution and cytokine levels in induced sputum from healthy subjects and patients with asthma after using different nebulizer techniques.

Koc-Günel S, Schubert R, Zielen S, Rosewich M.

BMC Pulm Med. 2018 Jul 13;18(1):115. doi: 10.1186/s12890-018-0683-8.

15.

Randomized controlled trials define shape of dose response for Pollinex Quattro Birch allergoid immunotherapy.

Worm M, Higenbottam T, Pfaar O, Mösges R, Aberer W, Gunawardena K, Wessiepe D, Lee D, Kramer MF, Skinner M, Lees B, Zielen S.

Allergy. 2018 Sep;73(9):1812-1822. doi: 10.1111/all.13478. Epub 2018 Jun 19.

16.

Long-term effect of monophosphoryl lipid A adjuvanted specific immunotherapy in patients with grass pollen allergy.

Zielen S, Gabrielpillai J, Herrmann E, Schulze J, Schubert R, Rosewich M.

Immunotherapy. 2018 Jun;10(7):529-536. doi: 10.2217/imt-2018-0004. Epub 2018 Mar 22.

PMID:
29562801
17.

Exhaled NO as a predictor of exercise-induced asthma in cold air.

Dreßler M, Salzmann-Manrique E, Zielen S, Schulze J.

Nitric Oxide. 2018 Jun 1;76:45-52. doi: 10.1016/j.niox.2018.03.004. Epub 2018 Mar 8.

PMID:
29526567
18.

Oxidative stress-driven pulmonary inflammation and fibrosis in a mouse model of human ataxia-telangiectasia.

Duecker R, Baer P, Eickmeier O, Strecker M, Kurz J, Schaible A, Henrich D, Zielen S, Schubert R.

Redox Biol. 2018 Apr;14:645-655. doi: 10.1016/j.redox.2017.11.006. Epub 2017 Nov 10.

19.

Comparison of two different assays and the predictive value of allergen components in house dust mite allergy.

Schulze J, Leberkuehne L, Salzmann-Manrique E, Schubert R, Zielen S, Rosewich M.

Immunotherapy. 2017 Nov;9(15):1253-1262. doi: 10.2217/imt-2017-0084.

PMID:
29130795
20.

Grass pollen sublingual immunotherapy tablets provide long-term relief of grass pollen-associated allergic rhinitis and reduce the risk of asthma: findings from a retrospective, real-world database subanalysis.

Devillier P, Wahn U, Zielen S, Heinrich J.

Expert Rev Clin Immunol. 2017 Dec;13(12):1199-1206. doi: 10.1080/1744666X.2017.1398082. Epub 2017 Nov 6.

PMID:
29072507
21.

Growth hormone treatment in patients with ataxia telangiectasia.

Woelke S, Pommerening H, Kieslich M, Schubert R, Zielen S.

Growth Factors. 2017 Jun;35(2-3):125-130. doi: 10.1080/08977194.2017.1367681.

PMID:
28948852
22.

Omalizumab effectively protects against early and late allergic responses in asthma after 4 weeks.

Trischler J, Lieb A, Arnold M, Schulze J, Rosewich M, Schubert R, Bottoli I, Zielen S.

Allergy. 2017 Dec;72(12):1912-1915. doi: 10.1111/all.13217. Epub 2017 Jun 28.

PMID:
28581121
23.

Sublingual immunotherapy provides long-term relief in allergic rhinitis and reduces the risk of asthma: A retrospective, real-world database analysis.

Zielen S, Devillier P, Heinrich J, Richter H, Wahn U.

Allergy. 2018 Jan;73(1):165-177. doi: 10.1111/all.13213. Epub 2017 Aug 10.

24.

Genomic profiling of Acute lymphoblastic leukemia in ataxia telangiectasia patients reveals tight link between ATM mutations and chromothripsis.

Ratnaparkhe M, Hlevnjak M, Kolb T, Jauch A, Maass KK, Devens F, Rode A, Hovestadt V, Korshunov A, Pastorczak A, Mlynarski W, Sungalee S, Korbel J, Hoell J, Fischer U, Milde T, Kramm C, Nathrath M, Chrzanowska K, Tausch E, Takagi M, Taga T, Constantini S, Loeffen J, Meijerink J, Zielen S, Gohring G, Schlegelberger B, Maass E, Siebert R, Kunz J, Kulozik AE, Worst B, Jones DT, Pfister SM, Zapatka M, Lichter P, Ernst A.

Leukemia. 2017 Oct;31(10):2048-2056. doi: 10.1038/leu.2017.55. Epub 2017 Feb 15.

PMID:
28196983
25.

Pro-resolving lipid mediator Resolvin D1 serves as a marker of lung disease in cystic fibrosis.

Eickmeier O, Fussbroich D, Mueller K, Serve F, Smaczny C, Zielen S, Schubert R.

PLoS One. 2017 Feb 3;12(2):e0171249. doi: 10.1371/journal.pone.0171249. eCollection 2017.

26.

Short-Term Variation of Lung Function and Airway Inflammation in Children and Adolescents with Bronchiolitis Obliterans.

Eckrich J, Herrmann E, Voss S, Schubert R, Zielen S, Rosewich M.

Lung. 2016 Aug;194(4):571-9. doi: 10.1007/s00408-016-9907-y. Epub 2016 Jun 20.

PMID:
27325047
27.

Mucolytic Effectiveness of Tyloxapol in Chronic Obstructive Pulmonary Disease - A Double-Blind, Randomized Controlled Trial.

Koppitz M, Eschenburg C, Salzmann E, Rosewich M, Schubert R, Zielen S.

PLoS One. 2016 Jun 16;11(6):e0156999. doi: 10.1371/journal.pone.0156999. eCollection 2016.

28.

Combinations of distinct long-chain polyunsaturated fatty acid species for improved dietary treatment against allergic bronchial asthma.

Beermann C, Neumann S, Fußbroich D, Zielen S, Schubert R.

Nutrition. 2016 Nov-Dec;32(11-12):1165-70. doi: 10.1016/j.nut.2016.04.004. Epub 2016 May 6. Review.

PMID:
27297719
29.

Airway inflammation in mild cystic fibrosis.

Eckrich J, Zissler UM, Serve F, Leutz P, Smaczny C, Schmitt-Grohé S, Fussbroich D, Schubert R, Zielen S, Eickmeier O.

J Cyst Fibros. 2017 Jan;16(1):107-115. doi: 10.1016/j.jcf.2016.05.016. Epub 2016 Jun 11.

30.

Low-dose irradiation prior to bone marrow transplantation results in ATM activation and increased lethality in Atm-deficient mice.

Pietzner J, Merscher BM, Baer PC, Duecker RP, Eickmeier O, Fußbroich D, Bader P, Del Turco D, Henschler R, Zielen S, Schubert R.

Bone Marrow Transplant. 2016 Apr;51(4):619. doi: 10.1038/bmt.2016.22. No abstract available.

PMID:
27050750
31.

Induction of Bronchial Tolerance After 1 Cycle of Monophosphoryl-A-Adjuvanted Specific Immunotherapy in Children With Grass Pollen Allergies.

Rosewich M, Girod K, Zielen S, Schubert R, Schulze J.

Allergy Asthma Immunol Res. 2016 May;8(3):257-63. doi: 10.4168/aair.2016.8.3.257.

32.

Impulse Oscillometry as a Predictor of Asthma Exacerbations in Young Children.

Schulze J, Biedebach S, Christmann M, Herrmann E, Voss S, Zielen S.

Respiration. 2016;91(2):107-14. doi: 10.1159/000442448. Epub 2016 Jan 13.

33.

Low-dose irradiation prior to bone marrow transplantation results in ATM activation and increased lethality in Atm-deficient mice.

Pietzner J, Merscher BM, Baer PC, Duecker RP, Eickmeier O, Fußbroich D, Bader P, Del Turco D, Henschler R, Zielen S, Schubert R.

Bone Marrow Transplant. 2016 Apr;51(4):560-7. doi: 10.1038/bmt.2015.334. Epub 2016 Jan 11. Erratum in: Bone Marrow Transplant. 2016 Apr;51(4):619.

PMID:
26752140
34.

Comment on: Treatment of EBV-Associated Nodular Sclerosing Hodgkin Lymphoma in a Patient With Ataxia Telangiectasia With Brentuximab Vedotin and Reduced COPP Plus Rituximab.

Zielen S.

Pediatr Blood Cancer. 2016 May;63(5):946. doi: 10.1002/pbc.25883. Epub 2015 Dec 31. No abstract available.

PMID:
26719151
35.

Body composition, muscle strength and hormonal status in patients with ataxia telangiectasia: a cohort study.

Pommerening H, van Dullemen S, Kieslich M, Schubert R, Zielen S, Voss S.

Orphanet J Rare Dis. 2015 Dec 9;10:155. doi: 10.1186/s13023-015-0373-z.

36.

ERS statement on the multidisciplinary respiratory management of ataxia telangiectasia.

Bhatt JM, Bush A, van Gerven M, Nissenkorn A, Renke M, Yarlett L, Taylor M, Tonia T, Warris A, Zielen S, Zinna S, Merkus PJ; European Respiratory Society.

Eur Respir Rev. 2015 Dec;24(138):565-81. doi: 10.1183/16000617.0066-2015. Review.

37.

Ataxia telangiectasia: why should the ERS care?

Bhatt JM, Bush A, van Gerven M, Nissenkorn A, Renke M, Yarlett L, Taylor M, Tonia T, Warris A, Zielen S, Zinna S, Merkus PJ.

Eur Respir J. 2015 Dec;46(6):1557-60. doi: 10.1183/13993003.01456-2015. No abstract available.

38.

In Vitro Determination of Respimat® Dose Delivery in Children: An Evaluation Based on Inhalation Flow Profiles and Mouth-Throat Models.

Bickmann D, Kamin W, Sharma A, Wachtel H, Moroni-Zentgraf P, Zielen S.

J Aerosol Med Pulm Drug Deliv. 2016 Feb;29(1):76-85. doi: 10.1089/jamp.2014.1166. Epub 2015 Jun 22.

39.

Long-term lung function in postinfectious bronchiolitis obliterans.

Rosewich M, Eckrich J, Zielen S.

Thorax. 2015 Aug;70(8):792. doi: 10.1136/thoraxjnl-2015-206998. Epub 2015 Apr 28. No abstract available.

PMID:
25920327
40.

Is the raised volume rapid thoracic compression technique ready for use in clinical trials in infants with cystic fibrosis?

Matecki S, Kent L, de Boeck K, Le Bourgeois M, Zielen S, Braggion C, Arets HG, Bradley J, Davis S, Sermet I, Reix P; respiratory function group of the European Cystic Fibrosis Society Clinical Trial Network.

J Cyst Fibros. 2016 Jan;15(1):10-20. doi: 10.1016/j.jcf.2015.03.015. Epub 2015 Apr 15. Review.

41.

A Handling Study to Assess Use of the Respimat(®) Soft Mist™ Inhaler in Children Under 5 Years Old.

Kamin W, Frank M, Kattenbeck S, Moroni-Zentgraf P, Wachtel H, Zielen S.

J Aerosol Med Pulm Drug Deliv. 2015 Oct;28(5):372-81. doi: 10.1089/jamp.2014.1159. Epub 2015 Apr 6.

42.

Airway inflammation in children and adolescents with bronchiolitis obliterans.

Rosewich M, Zissler UM, Kheiri T, Voss S, Eickmeier O, Schulze J, Herrmann E, Dücker RP, Schubert R, Zielen S.

Cytokine. 2015 May;73(1):156-62. doi: 10.1016/j.cyto.2014.10.026. Epub 2015 Mar 6.

PMID:
25748838
43.

Impact of soyasaponin I on TLR2 and TLR4 induced inflammation in the MUTZ-3-cell model.

Fußbroich D, Schubert R, Schneider P, Zielen S, Beermann C.

Food Funct. 2015 Mar;6(3):1001-10. doi: 10.1039/c4fo01065e.

PMID:
25685945
44.

Genotype alone does not predict the clinical course of SFTPC deficiency in paediatric patients.

Kröner C, Reu S, Teusch V, Schams A, Grimmelt AC, Barker M, Brand J, Gappa M, Kitz R, Kramer BW, Lange L, Lau S, Pfannenstiel C, Proesmans M, Seidenberg J, Sismanlar T, Aslan AT, Werner C, Zielen S, Zarbock R, Brasch F, Lohse P, Griese M.

Eur Respir J. 2015 Jul;46(1):197-206. doi: 10.1183/09031936.00129414. Epub 2015 Feb 5.

45.

Lipopolysaccharide challenge: immunological effects and safety in humans.

Zielen S, Trischler J, Schubert R.

Expert Rev Clin Immunol. 2015 Mar;11(3):409-18. doi: 10.1586/1744666X.2015.1012158. Epub 2015 Feb 6. Review.

PMID:
25655761
46.

Longitudinal measurement of airway inflammation over one year in children and adults with intermittent asthma.

Pedersen F, Holz O, Kanniess F, Zielen S, Schulze J, Gillissen A, von Berg A, Berdel D, Beier J, Beeh K, Schnoor M, Magnussen H.

BMC Res Notes. 2014 Dec 17;7:925. doi: 10.1186/1756-0500-7-925.

47.

Can we predict allergen-induced asthma in patients with allergic rhinitis?

Buslau A, Voss S, Herrmann E, Schubert R, Zielen S, Schulze J.

Clin Exp Allergy. 2014 Dec;44(12):1494-502. doi: 10.1111/cea.12427.

PMID:
25270425
48.

Growth retardation and growth hormone deficiency in patients with Ataxia telangiectasia.

Voss S, Pietzner J, Hoche F, Taylor AM, Last JI, Schubert R, Zielen S.

Growth Factors. 2014 Jun;32(3-4):123-9. doi: 10.3109/08977194.2014.939805.

PMID:
25060036
49.

Altered mucosal immune response after acute lung injury in a murine model of Ataxia Telangiectasia.

Eickmeier O, Kim SY, Herrmann E, Döring C, Duecker R, Voss S, Wehner S, Hölscher C, Pietzner J, Zielen S, Schubert R.

BMC Pulm Med. 2014 May 29;14:93. doi: 10.1186/1471-2466-14-93.

50.

Lung clearance index: evidence for use in clinical trials in cystic fibrosis.

Kent L, Reix P, Innes JA, Zielen S, Le Bourgeois M, Braggion C, Lever S, Arets HG, Brownlee K, Bradley JM, Bayfield K, O'Neill K, Savi D, Bilton D, Lindblad A, Davies JC, Sermet I, De Boeck K; European Cystic Fibrosis Society Clinical Trial Network (ECFS-CTN) Standardisation Committee.

J Cyst Fibros. 2014 Mar;13(2):123-38. doi: 10.1016/j.jcf.2013.09.005. Epub 2013 Dec 5. Review.

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