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Items: 1 to 50 of 107

1.
2.

Disruption of pubertal onset by exogenous testosterone and estrogen in two species of rodents.

Pak TR, Lynch GR, Ziegler DM, Lunden JB, Tsai PS.

Am J Physiol Endocrinol Metab. 2003 Jan;284(1):E206-12. Epub 2002 Sep 11.

3.

An overview of the mechanism, substrate specificities, and structure of FMOs.

Ziegler DM.

Drug Metab Rev. 2002 Aug;34(3):503-11. Review.

PMID:
12214662
4.

Improving access to care at community mental health centers.

Ziegler DM, Calladine A, Evans L.

Behav Healthc Tomorrow. 2002 Jun;11(3):20-8. No abstract available.

PMID:
12085432
5.

Redox regulation of yeast flavin-containing monooxygenase.

Suh JK, Poulsen LL, Ziegler DM, Robertus JD.

Arch Biochem Biophys. 2000 Sep 15;381(2):317-22.

PMID:
11032421
6.
7.

Lysine 219 participates in NADPH specificity in a flavin-containing monooxygenase from Saccharomyces cerevisiae.

Suh JK, Poulsen LL, Ziegler DM, Robertus JD.

Arch Biochem Biophys. 1999 Dec 15;372(2):360-6.

PMID:
10600176
8.

Yeast flavin-containing monooxygenase generates oxidizing equivalents that control protein folding in the endoplasmic reticulum.

Suh JK, Poulsen LL, Ziegler DM, Robertus JD.

Proc Natl Acad Sci U S A. 1999 Mar 16;96(6):2687-91.

9.

N-Glycosylation of pig flavin-containing monooxygenase form 1: determination of the site of protein modification by mass spectrometry.

Korsmeyer KK, Guan S, Yang ZC, Falick AM, Ziegler DM, Cashman JR.

Chem Res Toxicol. 1998 Oct;11(10):1145-53.

PMID:
9778310
10.

Cost-effectiveness of clozapine therapy for severe psychosis.

Ghaemi SN, Ziegler DM, Peachey TJ, Goodwin FK.

Psychiatr Serv. 1998 Jun;49(6):829-31.

PMID:
9634167
11.

Molecular cloning and kinetic characterization of a flavin-containing monooxygenase from Saccharomyces cerevisiae.

Suh JK, Poulsen LL, Ziegler DM, Robertus JD.

Arch Biochem Biophys. 1996 Dec 15;336(2):268-74.

PMID:
8954574
12.
13.

Oxidation of aldehydes catalyzed by pig liver flavin-containing monooxygenase.

Chen GP, Poulsen LL, Ziegler DM.

Drug Metab Dispos. 1995 Dec;23(12):1390-3.

PMID:
8689949
14.

Multisubstrate flavin-containing monooxygenases: applications of mechanism to specificity.

Poulsen LL, Ziegler DM.

Chem Biol Interact. 1995 Apr 28;96(1):57-73. Review.

PMID:
7720105
15.

The oxidation of ebselen metabolites to thiol oxidants catalyzed by liver microsomes and perfused rat liver.

Akerboom TP, Sies H, Ziegler DM.

Arch Biochem Biophys. 1995 Jan 10;316(1):220-6.

PMID:
7840620
16.

Estimation of tissue cysteamine by quantitative thin-layer chromatography.

Ziegler DM, Poulsen LL.

Methods Enzymol. 1995;251:294-9. No abstract available.

PMID:
7651208
17.

Liver microsome and flavin-containing monooxygenase catalyzed oxidation of organic selenium compounds.

Chen GP, Ziegler DM.

Arch Biochem Biophys. 1994 Aug 1;312(2):566-72.

PMID:
8037472
18.

The mammalian flavin-containing monooxygenases: molecular characterization and regulation of expression.

Hines RN, Cashman JR, Philpot RM, Williams DE, Ziegler DM.

Toxicol Appl Pharmacol. 1994 Mar;125(1):1-6. Review.

PMID:
8128486
19.

Flavoenzymes inhibited by indomethacin.

Chen GP, Raybuck S, Ziegler DM.

Drug Metabol Drug Interact. 1994;11(2):153-60.

PMID:
12369598
20.

Recent studies on the structure and function of multisubstrate flavin-containing monooxygenases.

Ziegler DM.

Annu Rev Pharmacol Toxicol. 1993;33:179-99. Review. No abstract available.

PMID:
8494339
21.
22.

Use of thiocarbamides as selective substrate probes for isoforms of flavin-containing monooxygenases.

Guo WX, Poulsen LL, Ziegler DM.

Biochem Pharmacol. 1992 Nov 17;44(10):2029-37.

PMID:
1449520
23.

Oxidation of aldose reductase inhibitors ALO-4114 and ALO-3152 catalyzed by liver microsomes.

Kiss AD, Haggard K, Veltman JC, Ziegler DM.

Drug Metab Dispos. 1992 Nov-Dec;20(6):948-53.

PMID:
1362951
24.
25.

Effects of dietary protein-energy interrelationships on Holstein steer performance and ruminal bacterial fermentation in continuous culture.

Chester-Jones H, Stern MD, Metwally HM, Linn JG, Ziegler DM.

J Anim Sci. 1991 Dec;69(12):4956-66.

PMID:
1667012
27.

The 1990 Bernard B. Brodie Award Lecture. Unique properties of the enzymes of detoxication.

Ziegler DM.

Drug Metab Dispos. 1991 Sep-Oct;19(5):847-52. Review. No abstract available.

PMID:
1686226
28.

Cloning, primary sequence, and chromosomal mapping of a human flavin-containing monooxygenase (FMO1).

Dolphin C, Shephard EA, Povey S, Palmer CN, Ziegler DM, Ayesh R, Smith RL, Phillips IR.

J Biol Chem. 1991 Jul 5;266(19):12379-85.

29.

Bioactivation of xenobiotics by flavin-containing monooxygenases.

Ziegler DM.

Adv Exp Med Biol. 1991;283:41-50. Review. No abstract available.

PMID:
2069015
30.

The enzymes of detoxication.

Jakoby WB, Ziegler DM.

J Biol Chem. 1990 Dec 5;265(34):20715-8. Review. No abstract available.

31.
32.

Flavin-containing monooxygenases: enzymes adapted for multisubstrate specificity.

Ziegler DM.

Trends Pharmacol Sci. 1990 Aug;11(8):321-4. Review.

PMID:
2203193
33.
34.

The flavin-containing monooxygenase expressed in pig liver: primary sequence, distribution, and evidence for a single gene.

Gasser R, Tynes RE, Lawton MP, Korsmeyer KK, Ziegler DM, Philpot RM.

Biochemistry. 1990 Jan 9;29(1):119-24.

PMID:
2322534
35.

Oxygen radicals and drugs: in vitro measurements.

Ziegler DM, Kehrer JP.

Methods Enzymol. 1990;186:621-6. No abstract available.

PMID:
2172719
36.

Nitroglycerin and isosorbide dinitrate stimulation of glutathione disulfide efflux from perfused rat liver.

Hill KE, Ziegler DM, Konz KH, Haap M, Hunt RW Jr, Burk RF.

Biochem Pharmacol. 1989 Nov 1;38(21):3807-10.

PMID:
2512927
37.

The role of flavin-containing monooxygenase in the N-oxidation of the pyrrolizidine alkaloid senecionine.

Williams DE, Reed RL, Kedzierski B, Ziegler DM, Buhler DR.

Drug Metab Dispos. 1989 Jul-Aug;17(4):380-6.

PMID:
2571476
38.

Tissue and biliary glutathione disulfide in the perfused vitamin E-deficient rat liver.

Hill KE, Taylor MA, Ziegler DM, Burk RF.

Res Commun Chem Pathol Pharmacol. 1989 Mar;63(3):373-83.

PMID:
2727389
39.

Stereoselectivity in the N'-oxidation of nicotine isomers by flavin-containing monooxygenase.

Damani LA, Pool WF, Crooks PA, Kaderlik RK, Ziegler DM.

Mol Pharmacol. 1988 Jun;33(6):702-5.

PMID:
3380084
40.

Estimation of lipid concentrations on thin-layer plates by densitometry of transparent copies.

Nagata T, Poulsen LL, Ziegler DM.

Anal Biochem. 1988 Jun;171(2):248-55.

PMID:
2457336
41.

N-methylation: potential mechanism for metabolic activation of carcinogenic primary arylamines.

Ziegler DM, Ansher SS, Nagata T, Kadlubar FF, Jakoby WB.

Proc Natl Acad Sci U S A. 1988 Apr;85(8):2514-7.

42.

Effect of hypoxic perfusion on hepatic concentration and biliary release of glutathione disulfide.

Cummings SW, Hill KE, Burk RF, Ziegler DM.

Biochem Pharmacol. 1988 Mar 1;37(5):967-9. No abstract available.

PMID:
3345206
43.

Flavin-containing monooxygenases: catalytic mechanism and substrate specificities.

Ziegler DM.

Drug Metab Rev. 1988;19(1):1-32. Review. No abstract available.

PMID:
3293953
44.

Mechanisms for the generation of oxygen radicals by drugs.

Ziegler DM.

Basic Life Sci. 1988;49:729-38. Review. No abstract available.

PMID:
3074796
45.
46.

Cysteamine dioxygenase.

Richerson RB, Ziegler DM.

Methods Enzymol. 1987;143:410-5. No abstract available.

PMID:
3657558
47.

Cysteamine and cystamine.

Duffel MW, Logan DJ, Ziegler DM.

Methods Enzymol. 1987;143:149-54. No abstract available.

PMID:
3657527
48.

Cellular protein-mixed disulfides.

Lou MF, Poulsen LL, Ziegler DM.

Methods Enzymol. 1987;143:124-9. No abstract available.

PMID:
3657524
49.

Substrate specificity of the rabbit lung flavin-containing monooxygenase for amines: oxidation products of primary alkylamines.

Poulsen LL, Taylor K, Williams DE, Masters BS, Ziegler DM.

Mol Pharmacol. 1986 Dec;30(6):680-5.

PMID:
3785145
50.

Properties of an N,N-dimethyl-p-aminoazobenzene oxide reductase purified from rat liver cytosol.

Lashmet Johnson PR, Ziegler DM.

J Biochem Toxicol. 1986 Mar;1(1):15-27.

PMID:
3152268

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