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Items: 1 to 50 of 84

1.

Reverse Genetics for Type I Feline Coronavirus Field Isolate To Study the Molecular Pathogenesis of Feline Infectious Peritonitis.

Ehmann R, Kristen-Burmann C, Bank-Wolf B, König M, Herden C, Hain T, Thiel HJ, Ziebuhr J, Tekes G.

MBio. 2018 Jul 31;9(4). pii: e01422-18. doi: 10.1128/mBio.01422-18.

2.

Characterization of a bafinivirus exoribonuclease activity.

Durzynska I, Sauerwald M, Karl N, Madhugiri R, Ziebuhr J.

J Gen Virol. 2018 Sep;99(9):1253-1260. doi: 10.1099/jgv.0.001120. Epub 2018 Jul 30.

PMID:
30058998
3.

A Single-Center Study of Viral Respiratory Tract Infections in Hospitalized Children From the Kurdistan Region of Iraq.

Hassan DA, Rachid SK, Ziebuhr J.

Glob Pediatr Health. 2018 Jul 10;5:2333794X18784996. doi: 10.1177/2333794X18784996. eCollection 2018.

4.

Antiviral activity of K22 against members of the order Nidovirales.

Rappe JCF, de Wilde A, Di H, Müller C, Stalder H, V'kovski P, Snijder E, Brinton MA, Ziebuhr J, Ruggli N, Thiel V.

Virus Res. 2018 Feb 15;246:28-34. doi: 10.1016/j.virusres.2018.01.002. Epub 2018 Jan 11.

5.

Broad-spectrum antiviral activity of the eIF4A inhibitor silvestrol against corona- and picornaviruses.

Müller C, Schulte FW, Lange-Grünweller K, Obermann W, Madhugiri R, Pleschka S, Ziebuhr J, Hartmann RK, Grünweller A.

Antiviral Res. 2018 Feb;150:123-129. doi: 10.1016/j.antiviral.2017.12.010. Epub 2017 Dec 16.

PMID:
29258862
6.

Structural and functional conservation of cis-acting RNA elements in coronavirus 5'-terminal genome regions.

Madhugiri R, Karl N, Petersen D, Lamkiewicz K, Fricke M, Wend U, Scheuer R, Marz M, Ziebuhr J.

Virology. 2018 Apr;517:44-55. doi: 10.1016/j.virol.2017.11.025. Epub 2017 Dec 6.

PMID:
29223446
7.

Inhibition of Cytosolic Phospholipase A2α Impairs an Early Step of Coronavirus Replication in Cell Culture.

Müller C, Hardt M, Schwudke D, Neuman BW, Pleschka S, Ziebuhr J.

J Virol. 2018 Jan 30;92(4). pii: e01463-17. doi: 10.1128/JVI.01463-17. Print 2018 Feb 15.

8.

Identification and characterization of a Golgi retention signal in feline coronavirus accessory protein 7b.

Florek D, Ehmann R, Kristen-Burmann C, Lemmermeyer T, Lochnit G, Ziebuhr J, Thiel HJ, Tekes G.

J Gen Virol. 2017 Aug;98(8):2017-2029. doi: 10.1099/jgv.0.000879. Epub 2017 Jul 31.

PMID:
28758629
9.

The NF-κB-dependent and -independent transcriptome and chromatin landscapes of human coronavirus 229E-infected cells.

Poppe M, Wittig S, Jurida L, Bartkuhn M, Wilhelm J, Müller H, Beuerlein K, Karl N, Bhuju S, Ziebuhr J, Schmitz ML, Kracht M.

PLoS Pathog. 2017 Mar 29;13(3):e1006286. doi: 10.1371/journal.ppat.1006286. eCollection 2017 Mar.

10.

Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication.

Kindler E, Gil-Cruz C, Spanier J, Li Y, Wilhelm J, Rabouw HH, Züst R, Hwang M, V'kovski P, Stalder H, Marti S, Habjan M, Cervantes-Barragan L, Elliot R, Karl N, Gaughan C, van Kuppeveld FJ, Silverman RH, Keller M, Ludewig B, Bergmann CC, Ziebuhr J, Weiss SR, Kalinke U, Thiel V.

PLoS Pathog. 2017 Feb 3;13(2):e1006195. doi: 10.1371/journal.ppat.1006195. eCollection 2017 Feb.

11.

Rational Design of Novel Highly Potent and Selective Phosphatidylinositol 4-Kinase IIIβ (PI4KB) Inhibitors as Broad-Spectrum Antiviral Agents and Tools for Chemical Biology.

Mejdrová I, Chalupská D, Plačková P, Müller C, Šála M, Klíma M, Baumlová A, Hřebabecký H, Procházková E, Dejmek M, Strunin D, Weber J, Lee G, Matoušová M, Mertlíková-Kaiserová H, Ziebuhr J, Birkus G, Boura E, Nencka R.

J Med Chem. 2017 Jan 12;60(1):100-118. doi: 10.1021/acs.jmedchem.6b01465. Epub 2016 Dec 22.

PMID:
28004945
12.

Preface.

Ziebuhr J.

Adv Virus Res. 2016;96:xiii-xiv. doi: 10.1016/S0065-3527(16)30060-4. No abstract available.

PMID:
27712629
13.

The Nonstructural Proteins Directing Coronavirus RNA Synthesis and Processing.

Snijder EJ, Decroly E, Ziebuhr J.

Adv Virus Res. 2016;96:59-126. doi: 10.1016/bs.aivir.2016.08.008. Epub 2016 Sep 14. Review.

PMID:
27712628
14.

Coronavirus cis-Acting RNA Elements.

Madhugiri R, Fricke M, Marz M, Ziebuhr J.

Adv Virus Res. 2016;96:127-163. doi: 10.1016/bs.aivir.2016.08.007. Epub 2016 Sep 6. Review.

PMID:
27712622
15.

Identification of specific residues in avian influenza A virus NS1 that enhance viral replication and pathogenicity in mammalian systems.

Kanrai P, Mostafa A, Madhugiri R, Lechner M, Wilk E, Schughart K, Ylösmäki L, Saksela K, Ziebuhr J, Pleschka S.

J Gen Virol. 2016 Sep;97(9):2135-48. doi: 10.1099/jgv.0.000542. Epub 2016 Jul 12.

PMID:
27405649
16.

Characterization of the 3rd International Standard for hepatitis B virus surface antigen (HBsAg).

Seiz PL, Mohr C, Wilkinson DE, Ziebuhr J, Schüttler CG, Gerlich WH, Glebe D.

J Clin Virol. 2016 Sep;82:166-172. doi: 10.1016/j.jcv.2016.05.009. Epub 2016 Jun 3.

PMID:
27345250
17.

Proteolytic processing of mesonivirus replicase polyproteins by the viral 3C-like protease.

Blanck S, Ziebuhr J.

J Gen Virol. 2016 Jun;97(6):1439-1445. doi: 10.1099/jgv.0.000458. Epub 2016 Mar 15.

PMID:
26977900
18.

Phylogenetic analysis of human influenza A/H3N2 viruses isolated in 2015 in Germany indicates significant genetic divergence from vaccine strains.

Mostafa A, Abdelwhab el-SM, Slanina H, Hussein MA, Kuznetsova I, Schüttler CG, Ziebuhr J, Pleschka S.

Arch Virol. 2016 Jun;161(6):1505-15. doi: 10.1007/s00705-016-2815-x. Epub 2016 Mar 14.

PMID:
26973232
19.

Characterization of monoclonal antibodies against feline coronavirus accessory protein 7b.

Lemmermeyer T, Lamp B, Schneider R, Ziebuhr J, Tekes G, Thiel HJ.

Vet Microbiol. 2016 Feb 29;184:11-9. doi: 10.1016/j.vetmic.2015.12.009. Epub 2015 Dec 31.

PMID:
26854339
20.

The PB1 segment of an influenza A virus H1N1 2009pdm isolate enhances the replication efficiency of specific influenza vaccine strains in cell culture and embryonated eggs.

Mostafa A, Kanrai P, Ziebuhr J, Pleschka S.

J Gen Virol. 2016 Mar;97(3):620-31. doi: 10.1099/jgv.0.000390. Epub 2016 Jan 7.

PMID:
26743314
21.

Studies of nosocomial outbreaks of hepatitis B in nursing homes in Germany suggest a major role of hepatitis B e antigen expression in disease severity and progression.

Seiz PL, Slanina H, Ziebuhr J, Gerlich WH, Glebe D, Schüttler CG.

Int J Med Microbiol. 2015 Oct;305(7):663-72. doi: 10.1016/j.ijmm.2015.08.016. Epub 2015 Aug 21.

PMID:
26338147
22.

In Silico Prediction and Experimental Confirmation of HA Residues Conferring Enhanced Human Receptor Specificity of H5N1 Influenza A Viruses.

Schmier S, Mostafa A, Haarmann T, Bannert N, Ziebuhr J, Veljkovic V, Dietrich U, Pleschka S.

Sci Rep. 2015 Jun 19;5:11434. doi: 10.1038/srep11434.

23.

Influenza virus-induced caspase-dependent enlargement of nuclear pores promotes nuclear export of viral ribonucleoprotein complexes.

Mühlbauer D, Dzieciolowski J, Hardt M, Hocke A, Schierhorn KL, Mostafa A, Müller C, Wisskirchen C, Herold S, Wolff T, Ziebuhr J, Pleschka S.

J Virol. 2015 Jun;89(11):6009-21. doi: 10.1128/JVI.03531-14. Epub 2015 Mar 25.

24.

RNA structure analysis of alphacoronavirus terminal genome regions.

Madhugiri R, Fricke M, Marz M, Ziebuhr J.

Virus Res. 2014 Dec 19;194:76-89. doi: 10.1016/j.virusres.2014.10.001. Epub 2014 Oct 13. Review.

PMID:
25307890
25.

Characterization of an alphamesonivirus 3C-like protease defines a special group of nidovirus main proteases.

Blanck S, Stinn A, Tsiklauri L, Zirkel F, Junglen S, Ziebuhr J.

J Virol. 2014 Dec;88(23):13747-58. doi: 10.1128/JVI.02040-14. Epub 2014 Sep 17.

26.

Evidence for substrate binding-induced zwitterion formation in the catalytic Cys-His dyad of the SARS-CoV main protease.

Paasche A, Zipper A, Schäfer S, Ziebuhr J, Schirmeister T, Engels B.

Biochemistry. 2014 Sep 23;53(37):5930-46. doi: 10.1021/bi400604t. Epub 2014 Sep 7.

PMID:
25196915
27.

Development and evaluation of reverse transcription loop-mediated isothermal amplification assay for the detection of the fathead minnow nidovirus.

Zhang Q, Standish I, Winters AD, Puzach C, Ulferts R, Ziebuhr J, Faisal M.

J Virol Methods. 2014 Jun;202:39-45. doi: 10.1016/j.jviromet.2014.02.018. Epub 2014 Mar 1.

PMID:
24594288
28.

Sequestration by IFIT1 impairs translation of 2'O-unmethylated capped RNA.

Habjan M, Hubel P, Lacerda L, Benda C, Holze C, Eberl CH, Mann A, Kindler E, Gil-Cruz C, Ziebuhr J, Thiel V, Pichlmair A.

PLoS Pathog. 2013;9(10):e1003663. doi: 10.1371/journal.ppat.1003663. Epub 2013 Oct 3.

29.

Improved dual promotor-driven reverse genetics system for influenza viruses.

Mostafa A, Kanrai P, Ziebuhr J, Pleschka S.

J Virol Methods. 2013 Nov;193(2):603-10. doi: 10.1016/j.jviromet.2013.07.021. Epub 2013 Jul 22.

PMID:
23886561
30.

Middle East respiratory syndrome coronavirus (MERS-CoV): announcement of the Coronavirus Study Group.

de Groot RJ, Baker SC, Baric RS, Brown CS, Drosten C, Enjuanes L, Fouchier RA, Galiano M, Gorbalenya AE, Memish ZA, Perlman S, Poon LL, Snijder EJ, Stephens GM, Woo PC, Zaki AM, Zambon M, Ziebuhr J.

J Virol. 2013 Jul;87(14):7790-2. doi: 10.1128/JVI.01244-13. Epub 2013 May 15. No abstract available.

31.

Epstein-Barr virus-induced secondary high-grade transformation of Sjögren's syndrome-related mucosa-associated lymphoid tissue lymphoma.

Strunk JE, Schüttler C, Ziebuhr J, Stowasser M, Nöhte M, Mayer K, Bräuninger A, Gattenlöhner S.

J Clin Oncol. 2013 Jun 10;31(17):e265-8. doi: 10.1200/JCO.2012.46.8439. Epub 2013 Apr 29. No abstract available.

PMID:
23630202
32.

Identification and characterization of genetically divergent members of the newly established family Mesoniviridae.

Zirkel F, Roth H, Kurth A, Drosten C, Ziebuhr J, Junglen S.

J Virol. 2013 Jun;87(11):6346-58. doi: 10.1128/JVI.00416-13. Epub 2013 Mar 27.

33.

Antagonism of the interferon-induced OAS-RNase L pathway by murine coronavirus ns2 protein is required for virus replication and liver pathology.

Zhao L, Jha BK, Wu A, Elliott R, Ziebuhr J, Gorbalenya AE, Silverman RH, Weiss SR.

Cell Host Microbe. 2012 Jun 14;11(6):607-16. doi: 10.1016/j.chom.2012.04.011.

34.

Mesoniviridae: a proposed new family in the order Nidovirales formed by a single species of mosquito-borne viruses.

Lauber C, Ziebuhr J, Junglen S, Drosten C, Zirkel F, Nga PT, Morita K, Snijder EJ, Gorbalenya AE.

Arch Virol. 2012 Aug;157(8):1623-8. doi: 10.1007/s00705-012-1295-x. Epub 2012 Apr 24.

35.

An insect nidovirus emerging from a primary tropical rainforest.

Zirkel F, Kurth A, Quan PL, Briese T, Ellerbrok H, Pauli G, Leendertz FH, Lipkin WI, Ziebuhr J, Drosten C, Junglen S.

MBio. 2011 Jun 14;2(3):e00077-11. doi: 10.1128/mBio.00077-11. Print 2011.

36.

The ADP-ribose-1''-monophosphatase domains of severe acute respiratory syndrome coronavirus and human coronavirus 229E mediate resistance to antiviral interferon responses.

Kuri T, Eriksson KK, Putics A, Züst R, Snijder EJ, Davidson AD, Siddell SG, Thiel V, Ziebuhr J, Weber F.

J Gen Virol. 2011 Aug;92(Pt 8):1899-905. doi: 10.1099/vir.0.031856-0. Epub 2011 Apr 27.

PMID:
21525212
37.

Nidovirus ribonucleases: Structures and functions in viral replication.

Ulferts R, Ziebuhr J.

RNA Biol. 2011 Mar-Apr;8(2):295-304. Epub 2011 Mar 1. Review.

PMID:
21422822
38.

Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5.

Züst R, Cervantes-Barragan L, Habjan M, Maier R, Neuman BW, Ziebuhr J, Szretter KJ, Baker SC, Barchet W, Diamond MS, Siddell SG, Ludewig B, Thiel V.

Nat Immunol. 2011 Feb;12(2):137-43. doi: 10.1038/ni.1979. Epub 2011 Jan 9.

39.

Characterization of Bafinivirus main protease autoprocessing activities.

Ulferts R, Mettenleiter TC, Ziebuhr J.

J Virol. 2011 Feb;85(3):1348-59. doi: 10.1128/JVI.01716-10. Epub 2010 Nov 10.

40.

Biochemical characterization of arterivirus nonstructural protein 11 reveals the nidovirus-wide conservation of a replicative endoribonuclease.

Nedialkova DD, Ulferts R, van den Born E, Lauber C, Gorbalenya AE, Ziebuhr J, Snijder EJ.

J Virol. 2009 Jun;83(11):5671-82. doi: 10.1128/JVI.00261-09. Epub 2009 Mar 18.

41.

Human coronavirus 229E papain-like proteases have overlapping specificities but distinct functions in viral replication.

Ziebuhr J, Schelle B, Karl N, Minskaia E, Bayer S, Siddell SG, Gorbalenya AE, Thiel V.

J Virol. 2007 Apr;81(8):3922-32. Epub 2007 Jan 24.

42.

ADP-ribose-1"-phosphatase activities of the human coronavirus 229E and SARS coronavirus X domains.

Putics A, Slaby J, Filipowicz W, Gorbalenya AE, Ziebuhr J.

Adv Exp Med Biol. 2006;581:93-6. No abstract available.

PMID:
17037511
43.

Non structural proteins 8 and 9 of human coronavirus 229E.

Ponnusamy R, Mesters JR, Ziebuhr J, Moll R, Hilgenfeld R.

Adv Exp Med Biol. 2006;581:49-54. No abstract available.

PMID:
17037503
44.

The coronavirus replicase: insights into a sophisticated enzyme machinery.

Ziebuhr J.

Adv Exp Med Biol. 2006;581:3-11. Review. No abstract available.

PMID:
17037497
45.

Characterization of White bream virus reveals a novel genetic cluster of nidoviruses.

Schütze H, Ulferts R, Schelle B, Bayer S, Granzow H, Hoffmann B, Mettenleiter TC, Ziebuhr J.

J Virol. 2006 Dec;80(23):11598-609. Epub 2006 Sep 20.

46.

Structural and functional basis for ADP-ribose and poly(ADP-ribose) binding by viral macro domains.

Egloff MP, Malet H, Putics A, Heinonen M, Dutartre H, Frangeul A, Gruez A, Campanacci V, Cambillau C, Ziebuhr J, Ahola T, Canard B.

J Virol. 2006 Sep;80(17):8493-502.

47.

Crystal structure and mechanistic determinants of SARS coronavirus nonstructural protein 15 define an endoribonuclease family.

Ricagno S, Egloff MP, Ulferts R, Coutard B, Nurizzo D, Campanacci V, Cambillau C, Ziebuhr J, Canard B.

Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):11892-7. Epub 2006 Aug 1.

48.

Discovery of an RNA virus 3'->5' exoribonuclease that is critically involved in coronavirus RNA synthesis.

Minskaia E, Hertzig T, Gorbalenya AE, Campanacci V, Cambillau C, Canard B, Ziebuhr J.

Proc Natl Acad Sci U S A. 2006 Mar 28;103(13):5108-13. Epub 2006 Mar 20.

49.

Nidovirales: evolving the largest RNA virus genome.

Gorbalenya AE, Enjuanes L, Ziebuhr J, Snijder EJ.

Virus Res. 2006 Apr;117(1):17-37. Epub 2006 Feb 28. Review.

PMID:
16503362
50.

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