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Items: 1 to 50 of 57

1.

Automated classification of cell morphology by coherence-controlled holographic microscopy.

Strbkova L, Zicha D, Vesely P, Chmelik R.

J Biomed Opt. 2017 Aug;22(8):1-9. doi: 10.1117/1.JBO.22.8.086008.

PMID:
28836416
2.

Mitotic catenation is monitored and resolved by a PKCε-regulated pathway.

Brownlow N, Pike T, Zicha D, Collinson L, Parker PJ.

Nat Commun. 2014 Dec 8;5:5685. doi: 10.1038/ncomms6685.

3.

Novel automated tracking analysis of particles subjected to shear flow: kindlin-3 role in B cells.

Willenbrock F, Zicha D, Hoppe A, Hogg N.

Biophys J. 2013 Sep 3;105(5):1110-22. doi: 10.1016/j.bpj.2013.06.051.

4.

Killing of Kras-mutant colon cancer cells via Rac-independent actin remodeling by the βGBP cytokine, a physiological PI3K inhibitor therapeutically effective in vivo.

Mallucci L, Shi DY, Davies D, Jordan P, Nicol A, Lotti L, Mariani-Costantini R, Verginelli F, Wells V, Zicha D.

Mol Cancer Ther. 2012 Sep;11(9):1884-93. doi: 10.1158/1535-7163.MCT-11-1041-T. Epub 2012 Jul 2.

5.

An siRNA screen identifies RSK1 as a key modulator of lung cancer metastasis.

Lara R, Mauri FA, Taylor H, Derua R, Shia A, Gray C, Nicols A, Shiner RJ, Schofield E, Bates PA, Waelkens E, Dallman M, Lamb J, Zicha D, Downward J, Seckl MJ, Pardo OE.

Oncogene. 2011 Aug 11;30(32):3513-21. doi: 10.1038/onc.2011.61. Epub 2011 Mar 21.

PMID:
21423205
6.

Regulation of lymphatic-blood vessel separation by endothelial Rac1.

D'Amico G, Jones DT, Nye E, Sapienza K, Ramjuan AR, Reynolds LE, Robinson SD, Kostourou V, Martinez D, Aubyn D, Grose R, Thomas GJ, Spencer-Dene B, Zicha D, Davies D, Tybulewicz V, Hodivala-Dilke KM.

Development. 2009 Dec;136(23):4043-53. doi: 10.1242/dev.035014. Erratum in: Development. 2010 Jan;137(2):359.

7.

EKV mutant connexin 31 associated cell death is mediated by ER stress.

Tattersall D, Scott CA, Gray C, Zicha D, Kelsell DP.

Hum Mol Genet. 2009 Dec 15;18(24):4734-45. doi: 10.1093/hmg/ddp436. Epub 2009 Sep 14.

8.

Cdc42 and Rac family GTPases regulate mode and speed but not direction of primary fibroblast migration during platelet-derived growth factor-dependent chemotaxis.

Monypenny J, Zicha D, Higashida C, Oceguera-Yanez F, Narumiya S, Watanabe N.

Mol Cell Biol. 2009 May;29(10):2730-47. doi: 10.1128/MCB.01285-08. Epub 2009 Mar 9.

9.

Novel shear flow assay provides evidence for non-linear modulation of cancer invasion.

Hagglund S, Hoppe A, Aubyn D, Cavanna T, Jordan P, Zicha D.

Front Biosci (Landmark Ed). 2009 Jan 1;14:3085-93.

PMID:
19273259
10.

Fluorescence localization after photobleaching (FLAP).

Dunn GA, Holt MR, Soong DY, Gray C, Zicha D.

Curr Protoc Cell Biol. 2004 Oct;Chapter 21:Unit 21.2. doi: 10.1002/0471143030.cb2102s24. Review.

PMID:
18228451
11.

Intermediate-affinity LFA-1 binds alpha-actinin-1 to control migration at the leading edge of the T cell.

Stanley P, Smith A, McDowall A, Nicol A, Zicha D, Hogg N.

EMBO J. 2008 Jan 9;27(1):62-75. Epub 2007 Dec 13.

12.

Biophysical characterization of an integrin-targeted lipopolyplex gene delivery vector.

Mustapa MF, Bell PC, Hurley CA, Nicol A, Guénin E, Sarkar S, Writer MJ, Barker SE, Wong JB, Pilkington-Miksa MA, Papahadjopoulos-Sternberg B, Shamlou PA, Hailes HC, Hart SL, Zicha D, Tabor AB.

Biochemistry. 2007 Nov 13;46(45):12930-44. Epub 2007 Oct 13.

PMID:
17935306
13.

Inhibition of invasion and induction of apoptosis by selenium in human malignant brain tumour cells in vitro.

Rooprai HK, Kyriazis I, Nuttall RK, Edwards DR, Zicha D, Aubyn D, Davies D, Gullan R, Pilkington GJ.

Int J Oncol. 2007 May;30(5):1263-71.

PMID:
17390030
14.

Evidence for protein 4.1B acting as a metastasis suppressor.

Cavanna T, Pokorná E, Veselý P, Gray C, Zicha D.

J Cell Sci. 2007 Feb 15;120(Pt 4):606-16. Epub 2007 Jan 30.

15.

Guidance of bidirectional motor complexes by mRNA cargoes through control of dynein number and activity.

Bullock SL, Nicol A, Gross SP, Zicha D.

Curr Biol. 2006 Jul 25;16(14):1447-52.

16.

Elimination of plasma membrane phosphatidylinositol (4,5)-bisphosphate is required for exocytosis from mast cells.

Hammond GR, Dove SK, Nicol A, Pinxteren JA, Zicha D, Schiavo G.

J Cell Sci. 2006 May 15;119(Pt 10):2084-94.

17.

Ephrin-B2 controls cell motility and adhesion during blood-vessel-wall assembly.

Foo SS, Turner CJ, Adams S, Compagni A, Aubyn D, Kogata N, Lindblom P, Shani M, Zicha D, Adams RH.

Cell. 2006 Jan 13;124(1):161-73.

19.

The class II phosphoinositide 3-kinase PI3K-C2beta regulates cell migration by a PtdIns3P dependent mechanism.

Domin J, Harper L, Aubyn D, Wheeler M, Florey O, Haskard D, Yuan M, Zicha D.

J Cell Physiol. 2005 Dec;205(3):452-62.

PMID:
16113997
20.

Connexin interaction patterns in keratinocytes revealed morphologically and by FRET analysis.

Di WL, Gu Y, Common JE, Aasen T, O'Toole EA, Kelsell DP, Zicha D.

J Cell Sci. 2005 Apr 1;118(Pt 7):1505-14. Epub 2005 Mar 15.

21.

Spatially distinct binding of Cdc42 to PAK1 and N-WASP in breast carcinoma cells.

Parsons M, Monypenny J, Ameer-Beg SM, Millard TH, Machesky LM, Peter M, Keppler MD, Schiavo G, Watson R, Chernoff J, Zicha D, Vojnovic B, Ng T.

Mol Cell Biol. 2005 Mar;25(5):1680-95.

22.

PKC controls HGF-dependent c-Met traffic, signalling and cell migration.

Kermorgant S, Zicha D, Parker PJ.

EMBO J. 2004 Oct 1;23(19):3721-34. Epub 2004 Sep 23.

23.
24.

The Drosophila hairy RNA localization signal modulates the kinetics of cytoplasmic mRNA transport.

Bullock SL, Zicha D, Ish-Horowicz D.

EMBO J. 2003 May 15;22(10):2484-94.

25.

Protein kinase C controls microtubule-based traffic but not proteasomal degradation of c-Met.

Kermorgant S, Zicha D, Parker PJ.

J Biol Chem. 2003 Aug 1;278(31):28921-9. Epub 2003 Apr 24.

26.

Rapid actin transport during cell protrusion.

Zicha D, Dobbie IM, Holt MR, Monypenny J, Soong DY, Gray C, Dunn GA.

Science. 2003 Apr 4;300(5616):142-5.

PMID:
12677069
27.

Two dynamic morphotypes of sarcoma cells, asymmetric stellate and triangle with leading lamella, are related to malignancy.

Pokorná E, Zicha D, Chaloupková A, Matousková E, Veselý P.

Folia Biol (Praha). 2003;49(1):33-9.

PMID:
12630666
28.

Localization of DNA polymerases eta and iota to the replication machinery is tightly co-ordinated in human cells.

Kannouche P, Fernández de Henestrosa AR, Coull B, Vidal AE, Gray C, Zicha D, Woodgate R, Lehmann AR.

EMBO J. 2003 Mar 3;22(5):1223-33.

29.

Localization of DNA polymerases eta and iota to the replication machinery is tightly co-ordinated in human cells.

Kannouche P, Fernández de Henestrosa AR, Coull B, Vidal AE, Gray C, Zicha D, Woodgate R, Lehmann AR.

EMBO J. 2002 Nov 15;21(22):6246-56. Corrected and republished in: EMBO J. 2003 Mar 3;22(5):1223-33.

30.

Defective trafficking and cell death is characteristic of skin disease-associated connexin 31 mutations.

Di WL, Monypenny J, Common JE, Kennedy CT, Holland KA, Leigh IM, Rugg EL, Zicha D, Kelsell DP.

Hum Mol Genet. 2002 Aug 15;11(17):2005-14.

PMID:
12165562
31.

Restoration of podosomes and chemotaxis in Wiskott-Aldrich syndrome macrophages following induced expression of WASp.

Jones GE, Zicha D, Dunn GA, Blundell M, Thrasher A.

Int J Biochem Cell Biol. 2002 Jul;34(7):806-15.

PMID:
11950596
32.

Fluorescence localization after photobleaching (FLAP): a new method for studying protein dynamics in living cells.

Dunn GA, Dobbie IM, Monypenny J, Holt MR, Zicha D.

J Microsc. 2002 Jan;205(Pt 1):109-12.

33.

Ezrin is a downstream effector of trafficking PKC-integrin complexes involved in the control of cell motility.

Ng T, Parsons M, Hughes WE, Monypenny J, Zicha D, Gautreau A, Arpin M, Gschmeissner S, Verveer PJ, Bastiaens PI, Parker PJ.

EMBO J. 2001 Jun 1;20(11):2723-41.

34.

Specific changes to the mechanism of cell locomotion induced by overexpression of beta-actin.

Peckham M, Miller G, Wells C, Zicha D, Dunn GA.

J Cell Sci. 2001 Apr;114(Pt 7):1367-77.

35.

Rho GTPases and cell migration: measurement of macrophage chemotaxis.

Jones GE, Ridley AJ, Zicha D.

Methods Enzymol. 2000;325:449-62. No abstract available.

PMID:
11036626
36.

Effect of pH on proteinase secretion by transformed fibroblast populations.

Chaloupka J, Kucerová H, Váchová L, Krchnáková E, Chaloupková A, Pavlíková L, Zicha D, Veselý P.

Folia Biol (Praha). 1998;44(3):111-6.

PMID:
10730852
37.

Distinct PI(3)Ks mediate mitogenic signalling and cell migration in macrophages.

Vanhaesebroeck B, Jones GE, Allen WE, Zicha D, Hooshmand-Rad R, Sawyer C, Wells C, Waterfield MD, Ridley AJ.

Nat Cell Biol. 1999 May;1(1):69-71. No abstract available.

PMID:
10559867
38.

Using molecular genetics as a tool in understanding crawling cell locomotion in myoblasts.

Peckham M, Wells C, Taylor-Harris P, Coles D, Zicha D, Dunn GA.

Biochem Soc Symp. 1999;65:281-99. Review.

PMID:
10320945
39.

TGFbeta1 induces a cell-cycle-dependent increase in motility of epithelial cells.

Zicha D, Genot E, Dunn GA, Kramer IM.

J Cell Sci. 1999 Feb;112 ( Pt 4):447-54.

40.

Disruption of the talin gene compromises focal adhesion assembly in undifferentiated but not differentiated embryonic stem cells.

Priddle H, Hemmings L, Monkley S, Woods A, Patel B, Sutton D, Dunn GA, Zicha D, Critchley DR.

J Cell Biol. 1998 Aug 24;142(4):1121-33.

41.

Chemotaxis of macrophages is abolished in the Wiskott-Aldrich syndrome.

Zicha D, Allen WE, Brickell PM, Kinnon C, Dunn GA, Jones GE, Thrasher AJ.

Br J Haematol. 1998 Jun;101(4):659-65.

PMID:
9674738
42.

A role for Cdc42 in macrophage chemotaxis.

Allen WE, Zicha D, Ridley AJ, Jones GE.

J Cell Biol. 1998 Jun 1;141(5):1147-57.

43.

Rapid, microtubule-dependent fluctuations of the cell margin.

Dunn GA, Zicha D, Fraylich PE.

J Cell Sci. 1997 Dec;110 ( Pt 24):3091-8.

44.
45.

Analyzing chemotaxis using the Dunn direct-viewing chamber.

Zicha D, Dunn G, Jones G.

Methods Mol Biol. 1997;75:449-57. Review. No abstract available.

PMID:
9276291
46.

Origins of the parasitophorous vacuole membrane of the malaria parasite: surface area of the parasitized red cell.

Dluzewski AR, Zicha D, Dunn GA, Gratzer WB.

Eur J Cell Biol. 1995 Dec;68(4):446-9.

PMID:
8690024
47.

Are growth factors chemotactic agents?

Zicha D, Dunn GA.

Exp Cell Res. 1995 Dec;221(2):526-9.

PMID:
7493653
48.

Dynamics of fibroblast spreading.

Dunn GA, Zicha D.

J Cell Sci. 1995 Mar;108 ( Pt 3):1239-49.

49.

Actin cytoskeleton and motility in rat sarcoma cell populations with different metastatic potential.

Pokorná E, Jordan PW, O'Neill CH, Zicha D, Gilbert CS, Veselý P.

Cell Motil Cytoskeleton. 1994;28(1):25-33.

PMID:
8044847
50.

Long-term chemotaxis of neutrophils in stable gradients: preliminary evidence of periodic behavior.

Dunn GA, Zicha D.

Blood Cells. 1993;19(1):25-39; discussion 39-41.

PMID:
8400310

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