Sort by
Items per page

Send to

Choose Destination

Search results

Items: 28


Analysis of Proline Substitutions Reveals the Plasticity and Sequence Sensitivity of Human IAPP Amyloidogenicity and Toxicity.

Ridgway Z, Eldrid CFS, Zhyvoloup A, Ben-Younis A, Noh D, Thalassinos K, Raleigh DP.

Biochemistry. 2020 Jan 10. doi: 10.1021/acs.biochem.9b01109. [Epub ahead of print]


Analysis of Prairie Vole Amylin Reveals the Importance of the N-Terminus and Residue 22 in Amyloidogenicity and Cytotoxicity.

Lee KH, Noh D, Zhyvoloup A, Raleigh D.

Biochemistry. 2019 Dec 27. doi: 10.1021/acs.biochem.9b00952. [Epub ahead of print]


Amyloidogenicity and cytotoxicity of des-Lys-1 human amylin provides insight into amylin self-assembly and highlights the difficulties of defining amyloidogenicity.

Lee KH, Zhyvoloup A, Raleigh D.

Protein Eng Des Sel. 2019 Dec 13;32(2):87-93. doi: 10.1093/protein/gzz036.


Covalent Aurora A regulation by the metabolic integrator coenzyme A.

Tsuchiya Y, Byrne DP, Burgess SG, Bormann J, Baković J, Huang Y, Zhyvoloup A, Yu BYK, Peak-Chew S, Tran T, Bellany F, Tabor AB, Chan AE, Guruprasad L, Garifulin O, Filonenko V, Vonderach M, Ferries S, Eyers CE, Carroll J, Skehel M, Bayliss R, Eyers PA, Gout I.

Redox Biol. 2020 Jan;28:101318. doi: 10.1016/j.redox.2019.101318. Epub 2019 Sep 5.


Coenzyme A and protein CoAlation levels are regulated in response to oxidative stress and during morphogenesis in Dictyostelium discoideum.

Aloum L, Brimson CA, Zhyvoloup A, Baines R, Baković J, Filonenko V, Thompson CRL, Gout I.

Biochem Biophys Res Commun. 2019 Apr 2;511(2):294-299. doi: 10.1016/j.bbrc.2019.02.031. Epub 2019 Feb 21.


Protein CoAlation and antioxidant function of coenzyme A in prokaryotic cells.

Tsuchiya Y, Zhyvoloup A, Baković J, Thomas N, Yu BYK, Das S, Orengo C, Newell C, Ward J, Saladino G, Comitani F, Gervasio FL, Malanchuk OM, Khoruzhenko AI, Filonenko V, Peak-Chew SY, Skehel M, Gout I.

Biochem J. 2018 Jun 6;475(11):1909-1937. doi: 10.1042/BCJ20180043.


Digoxin reveals a functional connection between HIV-1 integration preference and T-cell activation.

Zhyvoloup A, Melamed A, Anderson I, Planas D, Lee CH, Kriston-Vizi J, Ketteler R, Merritt A, Routy JP, Ancuta P, Bangham CRM, Fassati A.

PLoS Pathog. 2017 Jul 20;13(7):e1006460. doi: 10.1371/journal.ppat.1006460. eCollection 2017 Jul.


Protein CoAlation: a redox-regulated protein modification by coenzyme A in mammalian cells.

Tsuchiya Y, Peak-Chew SY, Newell C, Miller-Aidoo S, Mangal S, Zhyvoloup A, Bakovic J, Malanchuk O, Pereira GC, Kotiadis V, Szabadkai G, Duchen MR, Campbell M, Cuenca SR, Vidal-Puig A, James AM, Murphy MP, Filonenko V, Skehel M, Gout I.

Biochem J. 2017 Jul 11;474(14):2489-2508. doi: 10.1042/BCJ20170129.


Heat shock protein 90 controls HIV-1 reactivation from latency.

Anderson I, Low JS, Weston S, Weinberger M, Zhyvoloup A, Labokha AA, Corazza G, Kitson RA, Moody CJ, Marcello A, Fassati A.

Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):E1528-37. doi: 10.1073/pnas.1320178111. Epub 2014 Mar 31.


EDC4 interacts with and regulates the dephospho-CoA kinase activity of CoA synthase.

Gudkova D, Panasyuk G, Nemazanyy I, Zhyvoloup A, Monteil P, Filonenko V, Gout I.

FEBS Lett. 2012 Oct 19;586(20):3590-5. doi: 10.1016/j.febslet.2012.08.033. Epub 2012 Sep 13.


Identification of novel PTEN-binding partners: PTEN interaction with fatty acid binding protein FABP4.

Gorbenko O, Panayotou G, Zhyvoloup A, Volkova D, Gout I, Filonenko V.

Mol Cell Biochem. 2010 Apr;337(1-2):299-305. doi: 10.1007/s11010-009-0312-1.


mTORbeta splicing isoform promotes cell proliferation and tumorigenesis.

Panasyuk G, Nemazanyy I, Zhyvoloup A, Filonenko V, Davies D, Robson M, Pedley RB, Waterfield M, Gout I.

J Biol Chem. 2009 Nov 6;284(45):30807-14. doi: 10.1074/jbc.M109.056085. Epub 2009 Sep 2.


Biological properties of potent inhibitors of class I phosphatidylinositide 3-kinases: from PI-103 through PI-540, PI-620 to the oral agent GDC-0941.

Raynaud FI, Eccles SA, Patel S, Alix S, Box G, Chuckowree I, Folkes A, Gowan S, De Haven Brandon A, Di Stefano F, Hayes A, Henley AT, Lensun L, Pergl-Wilson G, Robson A, Saghir N, Zhyvoloup A, McDonald E, Sheldrake P, Shuttleworth S, Valenti M, Wan NC, Clarke PA, Workman P.

Mol Cancer Ther. 2009 Jul;8(7):1725-38. doi: 10.1158/1535-7163.MCT-08-1200. Epub 2009 Jul 7.


The identification of 2-(1H-indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a potent, selective, orally bioavailable inhibitor of class I PI3 kinase for the treatment of cancer .

Folkes AJ, Ahmadi K, Alderton WK, Alix S, Baker SJ, Box G, Chuckowree IS, Clarke PA, Depledge P, Eccles SA, Friedman LS, Hayes A, Hancox TC, Kugendradas A, Lensun L, Moore P, Olivero AG, Pang J, Patel S, Pergl-Wilson GH, Raynaud FI, Robson A, Saghir N, Salphati L, Sohal S, Ultsch MH, Valenti M, Wallweber HJ, Wan NC, Wiesmann C, Workman P, Zhyvoloup A, Zvelebil MJ, Shuttleworth SJ.

J Med Chem. 2008 Sep 25;51(18):5522-32. doi: 10.1021/jm800295d.


Nuclear export of S6K1 II is regulated by protein kinase CK2 phosphorylation at Ser-17.

Panasyuk G, Nemazanyy I, Zhyvoloup A, Bretner M, Litchfield DW, Filonenko V, Gout IT.

J Biol Chem. 2006 Oct 20;281(42):31188-201. Epub 2006 Aug 8.


Identification of a novel CoA synthase isoform, which is primarily expressed in the brain.

Nemazanyy I, Panasyuk G, Breus O, Zhyvoloup A, Filonenko V, Gout IT.

Biochem Biophys Res Commun. 2006 Mar 24;341(4):995-1000. Epub 2006 Jan 24.


Specific interaction between S6K1 and CoA synthase: a potential link between the mTOR/S6K pathway, CoA biosynthesis and energy metabolism.

Nemazanyy I, Panasyuk G, Zhyvoloup A, Panayotou G, Gout IT, Filonenko V.

FEBS Lett. 2004 Dec 17;578(3):357-62.


Identification of a novel binding partners for tumor suppressor PTEN by a yeast two-hybrid approach.

Gorbenko O, Kuznetsov V, Kukharenko O, Zhyvoloup A, Panasyuk G, Nemazanyy I, Filonenko V, Gout I.

Eksp Onkol. 2004 Mar;26(1):15-9.


Large-scale yeast transformation in low-percentage agarose medium.

Panasyuk G, Nemazanyy I, Filonenko V, Zhyvoloup A.

Biotechniques. 2004 Jan;36(1):40-2, 44. No abstract available.


Subcellular localization and regulation of coenzyme A synthase.

Zhyvoloup A, Nemazanyy I, Panasyuk G, Valovka T, Fenton T, Rebholz H, Wang ML, Foxon R, Lyzogubov V, Usenko V, Kyyamova R, Gorbenko O, Matsuka G, Filonenko V, Gout IT.

J Biol Chem. 2003 Dec 12;278(50):50316-21. Epub 2003 Sep 26.


Protein kinase C phosphorylates ribosomal protein S6 kinase betaII and regulates its subcellular localization.

Valovka T, Verdier F, Cramer R, Zhyvoloup A, Fenton T, Rebholz H, Wang ML, Gzhegotsky M, Lutsyk A, Matsuka G, Filonenko V, Wang L, Proud CG, Parker PJ, Gout IT.

Mol Cell Biol. 2003 Feb;23(3):852-63.


Ruk is ubiquitinated but not degraded by the proteasome.

Verdier F, Valovka T, Zhyvoloup A, Drobot LB, Buchman V, Waterfield M, Gout I.

Eur J Biochem. 2002 Jul;269(14):3402-8.


Molecular cloning of CoA Synthase. The missing link in CoA biosynthesis.

Zhyvoloup A, Nemazanyy I, Babich A, Panasyuk G, Pobigailo N, Vudmaska M, Naidenov V, Kukharenko O, Palchevskii S, Savinska L, Ovcharenko G, Verdier F, Valovka T, Fenton T, Rebholz H, Wang ML, Shepherd P, Matsuka G, Filonenko V, Gout IT.

J Biol Chem. 2002 Jun 21;277(25):22107-10. Epub 2002 Apr 29.


The nucleotide sequence of gene rpIJ encoding ribosomal protein L10 of Salmonella typhimurium.

Paton EB, Zolotukhin SB, Woodmaska MI, Kroupskaya IV, Zhyvoloup AN.

Nucleic Acids Res. 1990 May 11;18(9):2824. No abstract available.

Supplemental Content

Loading ...
Support Center