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CD226 deficiency on regulatory T cells aggravates renal fibrosis via up-regulation of Th2 cytokines through miR-340.

Mu Y, Zhang J, Liu Y, Ma J, Jiang D, Zhang X, Yi X, Cheng K, Shen S, Yang Y, Zhuang R, Zhang Y.

J Leukoc Biol. 2019 Dec 4. doi: 10.1002/JLB.2MA1119-174RR. [Epub ahead of print]


A novel small molecule compound VCP979 improves ventricular remodeling in murine models of myocardial ischemia/reperfusion injury.

Liu J, Meng Q, Liang X, Zhuang R, Yuan D, Ge X, Cao H, Lin F, Gong X, Fan H, Wang B, Zhou X, Liu Z.

Int J Mol Med. 2019 Nov 27. doi: 10.3892/ijmm.2019.4413. [Epub ahead of print]


Osteogenic stimulation of human dental pulp stem cells with self-setting biphasic calcium phosphate cement.

Gu Y, Zhuang R, Xie X, Bai Y.

J Biomed Mater Res B Appl Biomater. 2019 Nov 26. doi: 10.1002/jbm.b.34512. [Epub ahead of print]


Bodyweight-adjusted vaccination dose: a potential strategy against vaccine shortage.

Zhuang RY, Xu HG.

Public Health. 2019 Nov 22. pii: S0033-3506(19)30325-7. doi: 10.1016/j.puhe.2019.10.008. [Epub ahead of print] No abstract available.


Gender-neutral HPV vaccination in developing countries-is it time?

Zhuang RY, Xu HG.

Public Health. 2019 Nov 13;179:66-67. doi: 10.1016/j.puhe.2019.09.014. [Epub ahead of print] No abstract available.


AFC1 Compound Attenuated MI/R-Induced Ventricular Remodeling via Inhibiting PDGFR and STAT Pathway.

Liu J, Zhou X, Meng Q, Huang KW, Liu J, Tie J, Zhuang R, Chen G, Zhang Y, Wei L, Huang L, Li CG, Wang B, Fan H, Liu Z.

Front Pharmacol. 2019 Oct 15;10:1142. doi: 10.3389/fphar.2019.01142. eCollection 2019.


RILP Restricts Insulin Secretion Through Mediating Lysosomal Degradation of Proinsulin.

Zhou Y, Liu Z, Zhang S, Zhuang R, Liu H, Liu X, Qiu X, Zhang M, Zheng Y, Li L, Hong W, Wang T.

Diabetes. 2019 Oct 17. pii: db190086. doi: 10.2337/db19-0086. [Epub ahead of print]


Optimization of clinically applied orthodontic archwire electrothermal treatment conditions by heat tint and mechanical properties: An experimental study.

Gu Y, Zhuang R, Xie X, Zhang D, Bai Y.

Int Orthod. 2019 Sep 13. pii: S1761-7227(19)30109-3. doi: 10.1016/j.ortho.2019.07.004. [Epub ahead of print]


Immunoproteasome-selective inhibitors: An overview of recent developments as potential drugs for hematologic malignancies and autoimmune diseases.

Xi J, Zhuang R, Kong L, He R, Zhu H, Zhang J.

Eur J Med Chem. 2019 Nov 15;182:111646. doi: 10.1016/j.ejmech.2019.111646. Epub 2019 Aug 29. Review.


Circular RNA expression alterations in extracellular vesicles isolated from murine heart post ischemia/reperfusion injury.

Ge X, Meng Q, Zhuang R, Yuan D, Liu J, Lin F, Fan H, Zhou X.

Int J Cardiol. 2019 Dec 1;296:136-140. doi: 10.1016/j.ijcard.2019.08.024. Epub 2019 Aug 14.


Cold-inducible protein RBM3 mediates hypothermic neuroprotection against neurotoxin rotenone via inhibition on MAPK signalling.

Yang HJ, Zhuang RJ, Li YB, Li T, Yuan X, Lei BB, Xie YF, Wang M.

J Cell Mol Med. 2019 Oct;23(10):7010-7020. doi: 10.1111/jcmm.14588. Epub 2019 Aug 22.


Fe-modified Ce-MnOx/ACFN catalysts for selective catalytic reduction of NOx by NH3 at low-middle temperature.

Gu T, Gao F, Tang X, Yi H, Zhao S, Zaharaddeen S, Zhang R, Zhuang R, Ma Y.

Environ Sci Pollut Res Int. 2019 Sep;26(27):27940-27952. doi: 10.1007/s11356-019-05976-4. Epub 2019 Jul 26.


Design, synthesis, and biological evaluation of novel 3-(thiophen-2-ylthio)pyridine derivatives as potential multitarget anticancer agents.

Xi JJ, He RY, Zhang JK, Cai ZB, Zhuang RX, Zhao YM, Shao YD, Pan XW, Shi TT, Dong ZJ, Liu SR, Kong LM.

Arch Pharm (Weinheim). 2019 Aug;352(8):e1900024. doi: 10.1002/ardp.201900024. Epub 2019 Jul 24.


18F-labeled ethisterone derivative for progesterone receptor targeted PET imaging of breast cancer.

Gao F, Peng C, Zhuang R, Guo Z, Liu H, Huang L, Li H, Xu D, Wen X, Fang J, Zhang X.

Nucl Med Biol. 2019 May - Jun;72-73:62-69. doi: 10.1016/j.nucmedbio.2019.07.001. Epub 2019 Jul 12.


The Gut Microbial Metabolite Trimethylamine N-Oxide and Hypertension Risk: A Systematic Review and Dose-Response Meta-analysis.

Ge X, Zheng L, Zhuang R, Yu P, Xu Z, Liu G, Xi X, Zhou X, Fan H.

Adv Nutr. 2019 Jul 3. pii: nmz064. doi: 10.1093/advances/nmz064. [Epub ahead of print]


Overexpression of the peanut CLAVATA1-like leucine-rich repeat receptor-like kinase AhRLK1 confers increased resistance to bacterial wilt in tobacco.

Zhang C, Chen H, Zhuang RR, Chen YT, Deng Y, Cai TC, Wang SY, Liu QZ, Tang RH, Shan SH, Pan RL, Chen LS, Zhuang WJ.

J Exp Bot. 2019 Oct 15;70(19):5407-5421. doi: 10.1093/jxb/erz274.


Linc00423 as a tumor suppressor in retroperitoneal liposarcoma via activing MAPK signaling pathway through destabilizing of NFATC3.

Zhang Y, Tong H, He J, Shao Y, Guo X, Zhuang R, Yang J, Liu J, Ding Y, Liu W, Lu W, Zhou Y.

Cell Death Dis. 2019 Jun 3;10(6):430. doi: 10.1038/s41419-019-1658-2.


Does nab-paclitaxel have a higher incidence of peripheral neuropathy than solvent-based paclitaxel? Evidence from a systematic review and meta-analysis.

Guo X, Sun H, Dong J, Feng Y, Li H, Zhuang R, Wang P, Cai W, Zhou Y.

Crit Rev Oncol Hematol. 2019 Jul;139:16-23. doi: 10.1016/j.critrevonc.2019.04.021. Epub 2019 Apr 29.


Effect of lowering initiation thresholds in a primary care-based buprenorphine treatment program.

Payne BE, Klein JW, Simon CB, James JR, Jackson SL, Merrill JO, Zhuang R, Tsui JI.

Drug Alcohol Depend. 2019 Jul 1;200:71-77. doi: 10.1016/j.drugalcdep.2019.03.009. Epub 2019 May 1.


Machine learning for prediction of sudden cardiac death in heart failure patients with low left ventricular ejection fraction: study protocol for a retroprospective multicentre registry in China.

Meng F, Zhang Z, Hou X, Qian Z, Wang Y, Chen Y, Wang Y, Zhou Y, Chen Z, Zhang X, Yang J, Zhang J, Guo J, Li K, Chen L, Zhuang R, Jiang H, Zhou W, Tang S, Wei Y, Zou J.

BMJ Open. 2019 May 16;9(5):e023724. doi: 10.1136/bmjopen-2018-023724.


The genome of cultivated peanut provides insight into legume karyotypes, polyploid evolution and crop domestication.

Zhuang W, Chen H, Yang M, Wang J, Pandey MK, Zhang C, Chang WC, Zhang L, Zhang X, Tang R, Garg V, Wang X, Tang H, Chow CN, Wang J, Deng Y, Wang D, Khan AW, Yang Q, Cai T, Bajaj P, Wu K, Guo B, Zhang X, Li J, Liang F, Hu J, Liao B, Liu S, Chitikineni A, Yan H, Zheng Y, Shan S, Liu Q, Xie D, Wang Z, Khan SA, Ali N, Zhao C, Li X, Luo Z, Zhang S, Zhuang R, Peng Z, Wang S, Mamadou G, Zhuang Y, Zhao Z, Yu W, Xiong F, Quan W, Yuan M, Li Y, Zou H, Xia H, Zha L, Fan J, Yu J, Xie W, Yuan J, Chen K, Zhao S, Chu W, Chen Y, Sun P, Meng F, Zhuo T, Zhao Y, Li C, He G, Zhao Y, Wang C, Kavikishor PB, Pan RL, Paterson AH, Wang X, Ming R, Varshney RK.

Nat Genet. 2019 May;51(5):865-876. doi: 10.1038/s41588-019-0402-2. Epub 2019 May 1.


Radioiodinated progesterone derivative for progesterone receptor targeting with enhanced nucleus uptake via phenylboronic acid conjugation.

Gao F, Peng C, Li J, Zhuang R, Guo Z, Xu D, Su X, Zhang X.

J Labelled Comp Radiopharm. 2019 Jun 15;62(7):301-309. doi: 10.1002/jlcr.3741. Epub 2019 Jun 13.


High Expression of Human AugminComplex Submit 3 Indicates Poor Prognosis and Associates with Tumor Progression in Hepatocellular Carcinoma.

Zhang X, Zhuang R, Ye Q, Zhuo J, Chen K, Lu D, Wei X, Xie H, Xu X, Zheng S.

J Cancer. 2019 Feb 23;10(6):1434-1443. doi: 10.7150/jca.28317. eCollection 2019.


Gender-neutral HPV vaccination in Africa.

Zhuang RY, Goyal H, Xu HG.

Lancet Glob Health. 2019 May;7(5):e563. doi: 10.1016/S2214-109X(19)30073-7. No abstract available.


Inhibition of SOX15 Sensitizes Esophageal Squamous Carcinoma Cells to Paclitaxel.

Zhang M, Wang J, Gao T, Chen X, Xu Y, Yu X, Guo X, Zhuang R, Li Z, Wu H, Yu J.

Curr Mol Med. 2019;19(5):349-356. doi: 10.2174/1566524019666190405121139.


[CD226 knockout aggravates radiation-induced liver injury in mice].

Hu W, Zhang D, Zhou G, Zhang J, Yi X, Xie J, Zhang Y, Yang K, Zhuang R.

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2019 Jan;35(1):46-51. Chinese.


Alphalipoic Acid Prevents Oxidative Stress and Peripheral Neuropathy in Nab-Paclitaxel-Treated Rats through the Nrf2 Signalling Pathway.

Sun H, Guo X, Wang Z, Wang P, Zhang Z, Dong J, Zhuang R, Zhou Y, Ma G, Cai W.

Oxid Med Cell Longev. 2019 Feb 10;2019:3142732. doi: 10.1155/2019/3142732. eCollection 2019.


Online decision aids for primary cardiovascular disease prevention: systematic search, evaluation of quality and suitability for low health literacy patients.

Bonner C, Patel P, Fajardo MA, Zhuang R, Trevena L.

BMJ Open. 2019 Mar 13;9(3):e025173. doi: 10.1136/bmjopen-2018-025173.


Gut microbe-generated metabolite trimethylamine N-oxide and the risk of diabetes: A systematic review and dose-response meta-analysis.

Zhuang R, Ge X, Han L, Yu P, Gong X, Meng Q, Zhang Y, Fan H, Zheng L, Liu Z, Zhou X.

Obes Rev. 2019 Jun;20(6):883-894. doi: 10.1111/obr.12843. Epub 2019 Mar 13. Review.


Rational Design and Synthesis of a Deep-Ultraviolet Nonlinear Optical Fluorinated Orthophosphate: BaZn(PO4)F.

Tang XY, Mi JX, Zhuang RC, Wang SH, Wu SF, Pan Y, Huang YX.

Inorg Chem. 2019 Apr 1;58(7):4508-4514. doi: 10.1021/acs.inorgchem.9b00073. Epub 2019 Mar 13.


MicroRNA-23a depletion promotes apoptosis of ovarian cancer stem cell and inhibits cell migration by targeting DLG2.

Zhuang RJ, Bai XX, Liu W.

Cancer Biol Ther. 2019;20(6):897-911. doi: 10.1080/15384047.2019.1579960. Epub 2019 Mar 12.


Rapid one-step 18F-radiolabeling of biomolecules in aqueous media by organophosphine fluoride acceptors.

Hong H, Zhang L, Xie F, Zhuang R, Jiang D, Liu H, Li J, Yang H, Zhang X, Nie L, Li Z.

Nat Commun. 2019 Mar 1;10(1):989. doi: 10.1038/s41467-019-08953-0.


Dione-thiophene conjugate inhibits proliferation and metastasis of nasopharyngeal carcinoma cells through calcium binding protein-P down-regulation.

Zhang X, Zhuang R.

Eur J Med Chem. 2019 Apr 15;168:199-206. doi: 10.1016/j.ejmech.2019.01.051. Epub 2019 Jan 25.


Structural and functional insights into the role of a cupin superfamily isomerase in the biosynthesis of Choi moiety of aeruginosin.

Qiu X, Zhu W, Wang W, Jin H, Zhu P, Zhuang R, Yan X.

J Struct Biol. 2019 Mar 1;205(3):44-52. doi: 10.1016/j.jsb.2019.01.007. Epub 2019 Feb 10.


CD226 is involved in megakaryocyte activation and early-stage differentiation.

Zhang J, Zhuang R, Zhang X, Hu W, Cheng K, Jiang D, Shen S, Zhang Y, Ding Y, Zhang Y.

Mol Immunol. 2019 Mar;107:123-131. doi: 10.1016/j.molimm.2019.01.013. Epub 2019 Feb 6.


Radioiodinated Portable Albumin Binder as a Versatile Agent for in Vivo Imaging with Single-Photon Emission Computed Tomography.

Wen X, Shi C, Xu D, Zhang P, Li Z, Li J, Su X, Zhuang R, Liu T, Guo Z, Zhang X.

Mol Pharm. 2019 Feb 4;16(2):816-824. doi: 10.1021/acs.molpharmaceut.8b01116. Epub 2019 Jan 15.


Low-intensity pulsed ultrasound attenuates cardiac inflammation of CVB3-induced viral myocarditis via regulation of caveolin-1 and MAPK pathways.

Zheng C, Wu SM, Lian H, Lin YZ, Zhuang R, Thapa S, Chen QZ, Chen YF, Lin JF.

J Cell Mol Med. 2019 Mar;23(3):1963-1975. doi: 10.1111/jcmm.14098. Epub 2018 Dec 27.


Value of plasma SN-38 levels and DPD activity in irinotecan-based individualized chemotherapy for advanced colorectal cancer with heterozygous type UGT1A1*6 or UGT1A1*28.

Tian C, Ying H, Zhuang R, Zhang X, Lu H, Wang H, Wang S, Li Q, Wang C, Cai X.

Cancer Manag Res. 2018 Nov 22;10:6217-6226. doi: 10.2147/CMAR.S176918. eCollection 2018.


Astragaloside IV promotes the proliferation and migration of osteoblast-like cells through the hedgehog signaling pathway.

Guo LH, Cao Y, Zhuang RT, Han Y, Li J.

Int J Mol Med. 2019 Feb;43(2):830-838. doi: 10.3892/ijmm.2018.4013. Epub 2018 Dec 3.


Hypoxia-Inducible Factor 1 alpha (HIF-1╬▒)/Vascular Endothelial Growth Factor (VEGF) Pathway Participates in Angiogenesis of Myocardial Infarction in Muscone-Treated Mice: Preliminary Study.

Du Y, Ge Y, Xu Z, Aa N, Gu X, Meng H, Lin Z, Zhu D, Shi J, Zhuang R, Wu X, Wang X, Yang Z.

Med Sci Monit. 2018 Dec 8;24:8870-8877. doi: 10.12659/MSM.912051.


Prenatal propofol exposure downregulates NMDA receptor expression and causes cognitive and emotional disorders in rats.

Chen D, Qi X, Zhuang R, Cao J, Xu Y, Huang X, Li Y.

Eur J Pharmacol. 2019 Jan 15;843:268-276. doi: 10.1016/j.ejphar.2018.11.032. Epub 2018 Nov 22.


lncRNA DRHC inhibits proliferation and invasion in hepatocellular carcinoma via c-Myb-regulated MEK/ERK signaling.

Zhuang R, Zhang X, Lu D, Wang J, Zhuo J, Wei X, Ling Q, Xie H, Zheng S, Xu X.

Mol Carcinog. 2019 Mar;58(3):366-375. doi: 10.1002/mc.22934. Epub 2018 Nov 25.


Reprogramming Tumor-Associated Macrophages by Nanoparticle-Based Reactive Oxygen Species Photogeneration.

Shi C, Liu T, Guo Z, Zhuang R, Zhang X, Chen X.

Nano Lett. 2018 Nov 14;18(11):7330-7342. doi: 10.1021/acs.nanolett.8b03568. Epub 2018 Oct 24.


An Analysis of Relationship Between RAS Mutations and Prognosis of Primary Tumour Resection for Metastatic Colorectal Cancer Patients.

Liang L, Tian J, Yu Y, Wang Z, Peng K, Liu R, Wang Y, Xu X, Li H, Zhuang R, Cui Y, Zhu C, Liu T.

Cell Physiol Biochem. 2018;50(2):768-782. doi: 10.1159/000494242. Epub 2018 Oct 11.


Silencing LAIR-1 in human THP-1 macrophage increases foam cell formation by modulating PPAR╬│ and M2 polarization.

Yi X, Zhang J, Zhuang R, Wang S, Cheng S, Zhang D, Xie J, Hu W, Liu X, Zhang Y, Ding Y, Zhang Y.

Cytokine. 2018 Nov;111:194-205. doi: 10.1016/j.cyto.2018.08.028. Epub 2018 Aug 31.


Identification of novel N-acetylcysteine derivatives for the treatment of hepatocellular injury.

Liu S, Zhao Y, He R, Kong L, Xi J, Sun J, Shao Y, Pan X, Zhang J, Zhuang R.

Medchemcomm. 2017 Oct 19;8(12):2238-2247. doi: 10.1039/c7md00409e. eCollection 2017 Dec 1.


Discovery of AM-6226: A Potent and Orally Bioavailable GPR40 Full Agonist That Displays Efficacy in Nonhuman Primates.

Brown SP, Dransfield P, Vimolratana M, Zhu L, Luo J, Zhang J, Jiao X, Pattaropong V, Wong S, Zhuang R, Swaminath G, Houze JB, Lin DC.

ACS Med Chem Lett. 2018 Jun 6;9(7):757-760. doi: 10.1021/acsmedchemlett.8b00213. eCollection 2018 Jul 12.


Radioiodinated Pentixather for SPECT Imaging of Expression of the Chemokine Receptor CXCR4 in Rat Myocardial-Infarction-Reperfusion Models.

Li J, Peng C, Guo Z, Shi C, Zhuang R, Hong X, Wang X, Xu D, Zhang P, Zhang D, Liu T, Su X, Zhang X.

Anal Chem. 2018 Aug 7;90(15):9614-9620. doi: 10.1021/acs.analchem.8b02553. Epub 2018 Jul 26.


Body Mass Index Differences in the Gut Microbiota Are Gender Specific.

Gao X, Zhang M, Xue J, Huang J, Zhuang R, Zhou X, Zhang H, Fu Q, Hao Y.

Front Microbiol. 2018 Jun 22;9:1250. doi: 10.3389/fmicb.2018.01250. eCollection 2018.


pH-sensitive radiolabeled and superfluorinated ultra-small palladium nanosheet as a high-performance multimodal platform for tumor theranostics.

Guo Z, Chen M, Peng C, Mo S, Shi C, Fu G, Wen X, Zhuang R, Su X, Liu T, Zheng N, Zhang X.

Biomaterials. 2018 Oct;179:134-143. doi: 10.1016/j.biomaterials.2018.06.040. Epub 2018 Jun 30.


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